Abstract：
BACKGROUND:To study the value and safety of aqueous humor polymerase chain reaction (PCR) analysis for Herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus and Toxoplasma gondii in patients with uveitis. METHODS:Records of 45 consecutive patients with anterior and posterior uveitis who underwent AC paracentesis with PCR were reviewed. The main outcome measure was frequency of PCR positivity. Secondary outcomes were alteration of treatment, safety of paracentesis, and correlation of keratitic precipitates with PCR positivity, RESULTS: The overall PCR positivity was 48.9 % (22/45). Therapy was changed because of the PCR results in 14/45 patients (37.7 %). One patient experienced a paracentesis related complication (1/45, 2.2 %) without long-term sequelae. CONCLUSION:Aqueous PCR altered the diagnosis and treatment in over a third of our patients and was relatively safe. Aqueous PCR should be considered for uveitis of atypical clinical appearance, recurrent severe uveitis of uncertain etiology, and therapy refractory cases.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Chronopoulos A,Roquelaure D,Souteyrand G,Seebach JD,Schutz JS,Thumann Gdoi
10.1186/s12886-016-0369-zsubject
Has Abstractpub_date
2016-10-28 00:00:00pages
189issue
1issn
1471-2415pii
10.1186/s12886-016-0369-zjournal_volume
16pub_type
杂志文章abstract：BACKGROUND:To assess the efficacy of the intravitreal (IVT) injection of Triamcinolone Acetonide (TA) as compared to posterior subtenon (SBT) capsule injection for the treatment of cystoid diabetic macular edema. METHODS:Fourteen patients with type II diabetes mellitus and on insulin treatment, presenting diffuse cyst...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-8-5
更新日期：2008-03-17 00:00:00
abstract：BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01768-4
更新日期：2021-01-14 00:00:00
abstract：BACKGROUND:The purpose of this study was to identify the genetic cause and describe the clinical phenotype of Schnyder corneal dystrophy (SCD) in six unrelated probands. METHODS:We identified two white Czech, two white British and two South Asian families with a clinical diagnosis of SCD. Ophthalmic assessment include...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0918-8
更新日期：2018-09-17 00:00:00
abstract：BACKGROUND:A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, cornea...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01375-3
更新日期：2020-03-23 00:00:00
abstract：BACKGROUND:To assess the reliability of the measurements obtained with the PalmScan, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods. METHODS:Transversal, descriptive, and comparative study. We recorded the axial length (AL), anterior...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-10-8
更新日期：2010-03-24 00:00:00
abstract：BACKGROUND:To evaluate the relationships between Reichert Ocular Response Analyzer (ORA) parameters corneal hysteresis (CH) and corneal response factor (CRF) and ocular dimensions, age and intraocular pressure. METHODS:Two hundred and twelve eyes of 212 participants with no ocular pathology had CH and CRF measured wit...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-11
更新日期：2014-01-30 00:00:00
abstract：BACKGROUND:Despite the progress in vitreoretinal surgery and the importance of silicone oil as an adjunct for the treatment of complex forms of retinal detachment, controversy still surrounds the issue of selecting the proper oil viscosity for clinical use. Herein, we evaluate the outcomes of retinal detachment (RD) su...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-6-21
更新日期：2006-05-31 00:00:00
abstract：BACKGROUND:To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation. CASE PRESENTATION:A 56-year-old male patient presented at our outpatient clinic after becoming aware of dec...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0654-5
更新日期：2017-12-19 00:00:00
abstract：BACKGROUND:Stress-induced activation of the sympathetic nervous system leads to a cascade of metabolic reactions. Emotional stress is a more specific form of stress in which the stressor is a psychological response to a situation subjectively perceived as traumatic. Stress hormones can have a wide range of effects on t...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1075-4
更新日期：2019-03-08 00:00:00
abstract：BACKGROUND:Silicone oil tamponade has become a mainstay in treatment of advanced retinal detachment due to multiple etiologies. The aim of this study is to assess the characteristics, fates and complications of long-term silicone oil tamponade after par plana vitrectomy (PPV), and to compare the outcomes of different s...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01608-5
更新日期：2020-08-17 00:00:00
abstract：BACKGROUND:Bullous keratopathy (BK), a severe sight-threatening disorder can have a variety of etiologies such as prophylactic laser iridotomy, intraocular surgery, trauma, and other ocular disorders. However, there are cases of unknown origins, among which a unique clinical entity namely pseudoexfoliation syndrome (PE...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-12-17
更新日期：2012-06-22 00:00:00
abstract：BACKGROUND:Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection. CASE PRESENTATION:A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 we...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0400-z
更新日期：2017-01-18 00:00:00
abstract：BACKGROUND:There is no generally accepted medical or surgical treatment to stop the progressive course of retinitis pigmentosa. Previous studies have suggested lutein as a potential treatment with positive effects on macular pigment density. The objective of this study was to examine the effect of lutein supplementatio...
journal_title：BMC ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1186/1471-2415-6-23
更新日期：2006-06-07 00:00:00
abstract：BACKGROUND:To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea. METHODS:A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-4
更新日期：2014-01-10 00:00:00
abstract：BACKGROUND:To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play an important role in the pathophysiology of this case. CASE PRESENTATION:A 9 year-old male with ac...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-30
更新日期：2011-11-02 00:00:00
abstract：BACKGROUND:The aim of this study was to determine the interocular differences in the peripapillary retinal nerve fibre layer (RNFL), peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) in healthy adults with isometropia, using enhanced depth imaging optical coherence tomography (EDI SD-OCT)...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0361-7
更新日期：2016-10-19 00:00:00
abstract：BACKGROUND:To investigate the clinical features of diabetic macular edema (DME) in eyes with pachychoroid phenotypes using multimodal retinal imaging. METHODS:We retrospectively reviewed 210 eyes from 210 DME patients and analyzed the clinical and imaging parameters, including visual acuity, central macular thickness ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01663-y
更新日期：2020-10-02 00:00:00
abstract：BACKGROUND:To investigate the effect of idiopathic epiretinal membrane (ERM) on the retinal-image quality and psychophysical contrast sensitivity function (CSF). METHODS:Forty-four subjects with diagnosis of idiopathic unilateral ERM were enrolled in this cross-sectional observational clinical study. The fellow unaffe...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0957-1
更新日期：2018-11-07 00:00:00
abstract：BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-15-10
更新日期：2015-01-27 00:00:00
abstract：BACKGROUND:To report a case series in which a modified technique was used to remove retained submacular perfluorocarbon liquid (PFCL) secondary to vitreoretinal surgery for rhegmatogenous retinal detachment. CASE PRESENTATION:Four patients who had undergone pars plana vitrectomy for rhegmatogenous retinal detachment w...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0798-y
更新日期：2018-06-04 00:00:00
abstract：BACKGROUND:Graves' disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves' Ophthalmopathy. Not all patients respond well to the standard therapy of systemic glucocorticoid admini...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0718-1
更新日期：2018-02-27 00:00:00
abstract：BACKGROUND:In this analysis, we aimed to systematically compare the complications which were associated with femtosecond laser-assisted cataract surgery (FLACS) versus the conventional phacoemulsification surgery (CPE). METHODS:Commonly used search databases, specifically MEDLINE, Cochrane Central, EMBASE, and http://...
journal_title：BMC ophthalmology
pub_type： 杂志文章,meta分析
doi：10.1186/s12886-019-1190-2
更新日期：2019-08-09 00:00:00
abstract：BACKGROUND:Reports of central corneal thickness (CCT) among glaucoma patients, particularly for pseudoexfoliative glaucoma (PXG) and Primary Angle Closure Glaucoma (PACG) are scarce in the Sub-Saharan African (SSA) population. The aim of this study is to evaluate CCT in black patients with newly diagnosed glaucoma and ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0334-x
更新日期：2016-08-31 00:00:00
abstract：BACKGROUND:Sclopetaria is a rare ophthalmic finding in trauma CASE PRESENTATION:This is a report of a patient who developed macular holes from sclopetaria induced by indirect trauma. A 22-year-old male, suffered a gunshot wound that passed behind his eyes, resulting in bilateral macular hole formation CONCLUSION:To o...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-10-6
更新日期：2010-03-19 00:00:00
abstract：BACKGROUND:To report atypical features on Spectral domain optical coherence tomography (SD-OCT) in a case of non-familial pure adult nanophthalmos. CASE PRESENTATION:A 39 year old male hyperope was found to have biometric and fundus findings typical of nanophthalmos. The additional atypical features included serous pi...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-12-12
更新日期：2012-06-06 00:00:00
abstract：BACKGROUND:To report a case of multiple evanescent white dot syndrome (MEWDS) following simultaneous rabies vaccination. CASE PRESENTATION:Review of the clinical, laboratory, photographic, optical coherence tomographic (OCT), fundus autofluorescent, angiographic, electrophysiologic, and perimetric records of a patient...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0968-y
更新日期：2018-12-07 00:00:00
abstract：BACKGROUND:Orbital exenteration is a disfiguring procedure that aims to achieve local control. It is commonly a part of the management of malignant orbital tumor which is a life-threatening condition. It is necessary to determine predictive factors associated with overall survival (OS) following orbital exenteration. ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0850-y
更新日期：2018-07-28 00:00:00
abstract：BACKGROUND:To report the prevalence of ocular abnormalities and investigate visual acuity in a large cohort of retinitis pigmentosa (RP) patients in Western China. METHODS:The medical records and ophthalmic examination reports of 2127 eyes of 1065 RP patients at one eye hospital were retrospectively reviewed to determ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01797-z
更新日期：2021-01-18 00:00:00
abstract：BACKGROUND:The Heimann-Bielschowsky phenomenon (HBP) is an underrecognized condition characterized by slow, pendular, vertical oscillations of the eye accompanying monocular vision loss. Hypotropic dissociated vertical deviation (DVD) is another rare condition induced by asymmetric visual input. This report documents a...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01502-0
更新日期：2020-06-26 00:00:00
abstract：BACKGROUND:To compare the efficacy of phacoemulsification (PKE) combined with nonpenetrating deep sclerectomy (NPDS) with mitomycin C (MMC) versus XEN® gel stent with MMC. METHODS:In this nonrandomized, retrospective, comparative, single-center pilot study, 105 consecutive eyes of 75 patients with uncontrolled primary...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01492-z
更新日期：2020-06-16 00:00:00
