Abstract：
BACKGROUND:This paper presents and tests a comprehensive computerised system of analysis of digital images of posterior capsule opacification (PCO). It updates and expands significantly on a previous presentation to include facilities for selecting user defined central areas and for registering and subsequent merging of images for artefact removal. Also, the program is compiled and thus eliminates the need for specialised additional software. The system is referred to in this paper as the open-access systematic capsule assessment (OSCA). The system is designed to be evidence based, objective and openly available, improving on current systems of analysis. METHODS:Principal features of the OSCA system of analysis are discussed. Flash artefacts are automatically located in two PCO images and the images merged to produce a composite free from these artefacts. For this to be possible the second image has to be manipulated with a registration technique to bring it into alignment with the first. Further image processing and analysis steps use a location-sensitive entropy based texture analysis of PCO. Validity of measuring PCO progression of the whole new system is assessed along with visual significance of scores. Reliability of the system is assessed. RESULTS:Analysis of PCO by the system shows ability to detect early progression of PCO, as well as detection of more visually significant PCO. Images with no clinical PCO produce very low scores in the analysis. Reliability of the system of analysis is demonstrated. CONCLUSION:This system of PCO analysis is evidence-based, objective and clinically useful. It incorporates flash detection and removal as well as location sensitive texture analysis. It provides features and benefits not previously available to most researchers or clinicians. Substantial evidence is provided for this system's validity and reliability.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Aslam TM,Patton N,Rose CJdoi
10.1186/1471-2415-6-30subject
Has Abstractpub_date
2006-08-23 00:00:00pages
30issn
1471-2415pii
1471-2415-6-30journal_volume
6pub_type
杂志文章abstract：BACKGROUND:To understand which irregular corneal parameters determine the visual quality in keratoconus subjects. METHODS:The cross-sectional study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Amsler-Krumeich classification. We obtained measurements in two ways: (a) by project...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01737-x
更新日期：2020-11-26 00:00:00
abstract：BACKGROUND:Refraction change of silicone oil (SO) tamponade in phakic and aphakic eye has been studied thoroughly; however, it is rarely studied in pseudophakic eye. In this paper we aimed to deduce a theoretical formula predicting refractive shift of silicone oil tamponade in pseudophakic eye and compared it with clin...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0243-z
更新日期：2016-08-16 00:00:00
abstract：BACKGROUND:Glaucoma will undoubtedly impact on a person's ability to function as they go about their day-to-day life. The purpose of this study is to investigate the amount of published knowledge in quality of life (QoL) and visual disability studies for glaucoma, and make comparisons with similar research in other chr...
journal_title：BMC ophthalmology
pub_type： 信件
doi：10.1186/1471-2415-11-19
更新日期：2011-08-04 00:00:00
abstract：BACKGROUND:The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS:Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Departme...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0370-6
更新日期：2016-10-29 00:00:00
abstract：BACKGROUND:To investigate the clinical features of diabetic macular edema (DME) in eyes with pachychoroid phenotypes using multimodal retinal imaging. METHODS:We retrospectively reviewed 210 eyes from 210 DME patients and analyzed the clinical and imaging parameters, including visual acuity, central macular thickness ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01663-y
更新日期：2020-10-02 00:00:00
abstract：BACKGROUND:Retinal dystrophies display a considerably wide range of phenotypic variability, which can make diagnosis and clinical staging difficult. The aim of the study is to analyze the contribution of retro-mode imaging (RMI) and fundus autofluorescence (FAF) to the characterization of retinal dystrophies. METHODS:...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-12-8
更新日期：2012-05-15 00:00:00
abstract：BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01768-4
更新日期：2021-01-14 00:00:00
abstract：BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-15-10
更新日期：2015-01-27 00:00:00
abstract：BACKGROUND:Retinal tears complicating the course of a posterior vitreous detachment (PVD) may be unique or multiple, and when multiple they may occur simultaneously or subsequently at different moments in the evolution of a PVD. The purpose of our study was to analyze the prevalence of subsequent retinal tears (SRT) in...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0629-6
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:A 23 year old white male with a history of social and behavioural problems attempted to blind himself chemically, with alcohol, and mechanically, with a razor blade. METHODS:Observational case report of a patient who self-inflicted bilateral scleral lacerations with a razor blade, after losing his job. RES...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-9-14
更新日期：2009-12-10 00:00:00
abstract：BACKGROUND:To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea. METHODS:A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-4
更新日期：2014-01-10 00:00:00
abstract：BACKGROUND:This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. METHODS:In this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0503-6
更新日期：2017-07-04 00:00:00
abstract：BACKGROUND:To evaluate the efficacy and safety of intravitreal conbercept (KH902) as the primary treatment of choroidal neovascularization secondary to punctate inner choroidopathy. METHODS:This study was a retrospective, consecutive, observational case series. We reviewed medical records of 16 eyes (16 patients) with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0481-8
更新日期：2017-06-12 00:00:00
abstract：BACKGROUND:We explore and compare the advantages and disadvantages of different operating methods for a peripheral iridectomy (PI) for phakic posterior chamber implantable contact lens (ICL) implantation in patients with dark-brown irides. METHODS:Forty-six patients completed this prospective comparative study. Neodym...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0229-x
更新日期：2016-05-05 00:00:00
abstract：BACKGROUND:Retinal detachment is a disorder of the eye in which sensory retina separates from the retinal pigment epithelium (RPE) due to accumulation of fluid in subretinal space. Pharmacological stimulation of fluid reabsorption from subretinal space to choroid across the RPE has been suggested as a treatment strateg...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-33
更新日期：2011-11-15 00:00:00
abstract：BACKGROUND:The mechanism by which vitrectomy improves macular edema in patients with branch retinal vein occlusion remains unclear, although intraocular levels of vascular endothelial growth factor have been suggested to influence the visual prognosis and macular edema. METHODS:A series of 54 consecutive patients (54 ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-10-11
更新日期：2010-04-29 00:00:00
abstract：BACKGROUND:To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitre...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0828-9
更新日期：2018-06-27 00:00:00
abstract：BACKGROUND:The use of capsular tension ring (CTR) implantation to treat cataract patients with weak zonules is still controversial. The aim of this study was to examine the effects of CTR implantation on capsular stability after phacoemulsification in patients with weak zonules, especially patients who have undergone p...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01772-8
更新日期：2021-01-07 00:00:00
abstract：BACKGROUND:To report a patient who presented with bluish scleral discoloration, keratoconus, and progressive high myopia. CASE PRESENTATION:A 6-year-old Chinese female patient presented with a significant bluish discoloration of the sclera in both eyes and extreme corneal thinning with anterior corneal protrusion. Gen...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-018-0903-2
更新日期：2018-09-18 00:00:00
abstract：BACKGROUND:Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular pressure (IOP)-lowering medication change rates in patients newly treated with latanoprost or travoprost-...
journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1186/1471-2415-11-13
更新日期：2011-06-13 00:00:00
abstract：BACKGROUND:To investigate the effect of idiopathic epiretinal membrane (ERM) on the retinal-image quality and psychophysical contrast sensitivity function (CSF). METHODS:Forty-four subjects with diagnosis of idiopathic unilateral ERM were enrolled in this cross-sectional observational clinical study. The fellow unaffe...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0957-1
更新日期：2018-11-07 00:00:00
abstract：BACKGROUND:To study the influencing factors for different healing patterns of patients with idiopathic macular holes (IMH) after vitrectomy surgery performed with the internal limiting membrane (ILM) flap technique. METHODS:This study was a retrospective, consecutive, observational case series study. We recruited 52 I...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1265-0
更新日期：2019-12-21 00:00:00
abstract：BACKGROUND:Ocular hypotony results in an increased break down of the blood-aqueous barrier and an increase in inflammatory mediator release. We postulate that this release may lead to an increased risk of trabeculectomy failure through increased bleb scarring. This study was designed to try to address the question if h...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-5-7
更新日期：2005-04-05 00:00:00
abstract：BACKGROUND:The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole [V4c implantable collamer lens (ICL)] under bright and dark lighting conditions by means of the Optical Quality Analysis System™ (OQAS; Visiometrics, Terrassa, Spain). ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01340-0
更新日期：2020-03-04 00:00:00
abstract：BACKGROUND:Currently, various types of toric intraocular lenses (IOL) have been manufactured and can be divided into three types according to the location of correction component; front-toric IOL (correction on anterior IOL surface), back-toric IOL (correction on posterior IOL surface), and bi-toric IOL (correction on ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01439-4
更新日期：2020-04-28 00:00:00
abstract：BACKGROUND:To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy. METHODS:Neonatal C57BL/6 mice were exposed in hyperoxygen and returned to room air to develop oxygen-induced ret...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1292-x
更新日期：2020-01-06 00:00:00
abstract：BACKGROUND:To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS:This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0783-5
更新日期：2018-05-09 00:00:00
abstract：BACKGROUND:Few reports have described the ophthalmic complications that occur after maxillary orthognathic surgery. Since cases of decreased reflex tearing after maxillary orthognathic surgery are extremely rare, we describe 2 cases of loss of reflex tearing after maxillary orthognathic surgery. CASE PRESENTATION:Two ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-37
更新日期：2014-03-28 00:00:00
abstract：BACKGROUND:Dolosigranulum pigrum is a commensal inhabitant of the upper respiratory tract suspected to be responsible for ocular infections but no well-described case of D. pigrum corneal infection has been reported. Herein culture and PCR-sequencing-based investigations of corneal scraping specimens confirmed D. pigru...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-13-31
更新日期：2013-07-10 00:00:00
abstract：BACKGROUND:Nonarteritic ischemic optic neuropathy affects the anterior portion of the optic nerve and is characterized by sudden, painless visual loss. The affected eye has a relative afferent pupillary defect. The typical funduscopic appearance includes optic disc edema, with associated nerve fiber layer hemorrhage. R...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-6-32
更新日期：2006-10-11 00:00:00
