Ocular surface mucins and local inflammation--studies in genetically modified mouse lines.

abstract：BACKGROUND:Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, reviewing the results of our patients who had surgical correction with relaxed muscle positioning techniqu...

journal_title：BMC ophthalmology

authors： Sarici AM,Mergen B,Oguz V,Dogan C

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:We report a case of Meige's syndrome induced by an atypical antipsychotic (blonanserin) that presented with refractory dry eye disease. CASE PRESENTATION:A 37-year-old woman with a 6-month history of foreign body sensation in the eyes and difficulty in opening her eyes was treated at a local clinic for dry ...

journal_title：BMC ophthalmology

authors： Kim JE,Jung JW

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR). METHODS:Fifty eyes of 28 consecutive patients with DR were examined in this prospective observational study. A total of 46 eyes, 2...

journal_title：BMC ophthalmology

authors： Hirano T,Imai A,Kasamatsu H,Kakihara S,Toriyama Y,Murata T

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:To report a case of late closure of idiopathic full-thickness macular hole (FTMH) after vitrectomy with the inverted internal limiting membrane (ILM) technique. CASE PRESENTATION:A 68-year-old lady with a stage IV FTMH underwent pars plana vitrectomy with 25 gauge plus transconjunctival system, ILM peeling ...

journal_title：BMC ophthalmology

authors： Chung CY,Wong DS,Li KK

更新日期：2015-08-26 00:00:00

abstract：BACKGROUND:To evaluate the efficacy and safety of intravitreal conbercept (KH902) as the primary treatment of choroidal neovascularization secondary to punctate inner choroidopathy. METHODS:This study was a retrospective, consecutive, observational case series. We reviewed medical records of 16 eyes (16 patients) with...

journal_title：BMC ophthalmology

authors： Peng Y,Zhang X,Mi L,Liu B,Zuo C,Li M,Wen F

更新日期：2017-06-12 00:00:00

abstract：BACKGROUND:The present study sought to introduce clinical characteristics and stepwise surgical strategies of isolated complete cryptophthalmos, a rare, congenital ocular anomaly. CASE PRESENTATION:Retrospective, noncomparative, clinical study. Six patients with isolated complete cryptophthalmos were diagnosed at the ...

journal_title：BMC ophthalmology

authors： Liu Z,Xie B,Li Y,Ding J,Li D

更新日期：2019-07-31 00:00:00

abstract：BACKGROUND:Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic until now. Acetaldehyde dehydrogenase 2 (ALDH2), a major enzyme involved in aldehyde detoxification, h...

journal_title：BMC ophthalmology

authors： Yan W,Long P,Wei D,Yan W,Zheng X,Chen G,Wang J,Zhang Z,Chen T,Chen M

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...

journal_title：BMC ophthalmology

authors： Wang YZ,Zhang Y,Huang DS,Shi JT,Ma JM,Li B,Xu XL,Zhou Y,Gu HL

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS:Six focus group sessions were conducted at t...

journal_title：BMC ophthalmology

authors： Yeo S,Tong L

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Raised intraocular pressure (IOP) is the only causal risk factor for glaucoma that can be therapeutically manipulated to change the course of the disease process. Though Goldman applanation tonometry (GAT) is the "gold standard" for IOP measurement, readings of IOP with GAT are affected by central corneal th...

journal_title：BMC ophthalmology

authors： Gelaw Y

更新日期：2012-11-27 00:00:00

abstract：BACKGROUND:Previous analyses of real-life data indicated that injection frequency and health care costs did not differ for anti-VEGF treatment with aflibercept and ranibizumab. The objective of this study was to investigate whether this finding persisted when analysing a longer time period after licensing. METHODS:Ret...

journal_title：BMC ophthalmology

authors： Reich O,Schmid MK,Rapold R,Bachmann LM,Blozik E

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:The gold standard treatments in amblyopia are penalizing therapies, such as patching or blurring vision with atropine that are aimed at forcing the use of the amblyopic eye. However, in the last years, new therapies are being developed and validated, such as dichoptic visual training, aimed at stimulating th...

journal_title：BMC ophthalmology

authors： Žiak P,Holm A,Halička J,Mojžiš P,Piñero DP

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:To evaluate the prognosis of Chinese patients with lacrimal gland adenoid cystic carcinoma treated with eye-sparing surgery and adjuvant multimodal therapy. METHODS:The study included 24 consecutive patients with lacrimal gland adenoid cystic carcinoma treated at the Ninth People's Hospital of Shanghai from...

journal_title：BMC ophthalmology

authors： Yang J,Zhou C,Wang Y,Fan X,Jia R

更新日期：2019-06-08 00:00:00

abstract：BACKGROUND:Patients' feedback is of great importance in health care policy decisions. The Consumer Quality Index Cataract Questionnaire (CQI Cataract) was used to measure patients' experiences with quality of care after a cataract operation. This study aims to evaluate the reliability and the dimensional structure of t...

journal_title：BMC ophthalmology

authors： Stubbe JH,Brouwer W,Delnoij DM

更新日期：2007-09-19 00:00:00

abstract：BACKGROUND:Reports of central corneal thickness (CCT) among glaucoma patients, particularly for pseudoexfoliative glaucoma (PXG) and Primary Angle Closure Glaucoma (PACG) are scarce in the Sub-Saharan African (SSA) population. The aim of this study is to evaluate CCT in black patients with newly diagnosed glaucoma and ...

journal_title：BMC ophthalmology

authors： Tolesa K,Gessesse GW

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:Congenital cataract (CC) is a significant cause of lifelong visual loss, and its genetic diagnosis is challenging due to marked genetic heterogeneity. The purpose of this article is to report the genetic findings in sporadic and familial CC patients. METHODS:Patients (n = 53) who were clinically diagnosed w...

journal_title：BMC ophthalmology

authors： Fan F,Luo Y,Wu J,Gao C,Liu X,Mei H,Zhou X

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:Immune responses play a key role in the pathogenesis and progression of polypoidal choroidal vasculopath (PCV) and age-related macular degeneration (AMD). In this study, we determined the Th cell-associated immune responses by measuring the cytokine expression of peripheral blood mononuclear cells (PBMC) in ...

journal_title：BMC ophthalmology

authors： Yu Y,Ren XR,Wen F,Chen H,Su SB

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:The ocular presentation of Castleman's disease (CD)-associated paraneoplastic pemphigus (PNP) has rarely been reported. In this report, we describe a young patient with CD-associated PNP who had recurrent corneal ulceration in addition to cicatrizing conjunctivitis. CASE PRESENTATION:We describe a case of 2...

journal_title：BMC ophthalmology

authors： Gong H,Zhou S,Hu Y,Lan Y,Zeng H,Wang L,Liu Q,Wang M

更新日期：2016-07-12 00:00:00

abstract：BACKGROUND:Despite growing number of intraocular lens power calculation formulas, there is no evidence that these formulas have good predictive accuracy in pediatric, whose eyes are still undergoing rapid growth and refractive changes. This study is intended to compare the prediction error and the accuracy of predictab...

journal_title：BMC ophthalmology

authors： Jasman AA,Shaharuddin B,Noor RA,Ismail S,Ghani ZA,Embong Z

更新日期：2010-08-25 00:00:00

abstract：BACKGROUND:Docetaxel is a chemotherapeutic agent of the taxane class of drugs for the treatment of breast cancer. We present a female patient who noted decreased vision after docetaxel treatment. CASE PRESENTATION:A 45-year-old female patient received docetaxel treatment after resection of a breast carcinoma. Fundusco...

journal_title：BMC ophthalmology

authors： Enzsoly A,Kammerer K,Nemeth J,Schneider M

更新日期：2015-03-29 00:00:00

abstract：BACKGROUND:Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. METHODS:PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically ...

journal_title：BMC ophthalmology

authors： Meng B,Zhao L,Yin Y,Li H,Wang X,Yang X,You R,Wang J,Zhang Y,Wang H,Du R,Wang N,Zhan S,Wang Y

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:The tear film breakup time (tBUT) is a clinical evaluation of evaporative dry eye disease assessed by instilling topical fluorescein into the eyes. In the present study, we introduce a new diagnostic test, blinking tolerance time (BTT), for self-evaluation of tear-film stability. We compared the results with...

journal_title：BMC ophthalmology

authors： Hwang HB,Ku YH,Kim EC,Kim HS,Kim MS,Hwang HS

更新日期：2020-11-04 00:00:00

abstract：BACKGROUND:Tibetan Plateau is a highland area with special geographical location, time zone, and ethnic composition. We herein report the rationale, methodology and baseline data of the school-based childhood cohort study named Lhasa Childhood Eye Study (LCES), with the primary objective to pursue a comprehensive under...

journal_title：BMC ophthalmology

authors： Chen W,Fu J,Meng Z,Li L,Su H,Dai W,Yao Y

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:Retinal tears complicating the course of a posterior vitreous detachment (PVD) may be unique or multiple, and when multiple they may occur simultaneously or subsequently at different moments in the evolution of a PVD. The purpose of our study was to analyze the prevalence of subsequent retinal tears (SRT) in...

journal_title：BMC ophthalmology

authors： Crim N,Esposito E,Monti R,Correa LJ,Serra HM,Urrets-Zavalia JA

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, cornea...

journal_title：BMC ophthalmology

authors： Bair H,Lin CJ,Lai CT,Hsia NY,Tsai YY

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:Epidemic keratoconjunctivitis (EKC) is one of the most common eye infections worldwide. The analysis of clinical manifestations in different age groups help better know the disease. This study aims to provide more detailed analysis of 272 cases of EKC in 8 years, describe the differences of the clinical feat...

journal_title：BMC ophthalmology

authors： Hou W,Sun X,Feng J,Zhang Y,Wang Z

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:To report six cases of CD34+ fibroblastic mesenchymal tumours, which are uncommon neoplasms in the orbit. CASE PRESENTATION:Six patients presenting with proptosis and palpable mass who were later diagnosed with fibrous solitary tumours, fibrous histocytoma or haemangiopericytoma in the orbit were included. ...

journal_title：BMC ophthalmology

authors： Jung SK,Paik JS,Park GS,Yang SW

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. METHODS:This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having...

journal_title：BMC ophthalmology

authors： Ho YJ,Sun CC,Chen HC

更新日期：2018-04-23 00:00:00

abstract：BACKGROUND:While pars plana vitrectomy (PPV) has become the third most commonly performed surgery in the world, it can also induce multiple post complications easily. Among them, cataract progression is the most frequent one that can lead to blindness eventually. METHODS:To understand the underlying mechanisms of post...

journal_title：BMC ophthalmology

authors： Ji Y,Rong X,Lu Y

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:To report a patient who presented with bluish scleral discoloration, keratoconus, and progressive high myopia. CASE PRESENTATION:A 6-year-old Chinese female patient presented with a significant bluish discoloration of the sclera in both eyes and extreme corneal thinning with anterior corneal protrusion. Gen...

journal_title：BMC ophthalmology

authors： Wan Q,Tang J,Han Y,Xiao Q,Deng Y

更新日期：2018-09-18 00:00:00