Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study).

abstract：BACKGROUND:Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. METHODS:PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically ...

journal_title：BMC ophthalmology

authors： Meng B,Zhao L,Yin Y,Li H,Wang X,Yang X,You R,Wang J,Zhang Y,Wang H,Du R,Wang N,Zhan S,Wang Y

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:To screen for visual impairment in Malaysian preschool children. METHODS:Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs ste...

journal_title：BMC ophthalmology

authors： Premsenthil M,Manju R,Thanaraj A,Rahman SA,Kah TA

更新日期：2013-04-19 00:00:00

abstract：BACKGROUND:To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS:This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from ...

journal_title：BMC ophthalmology

authors： Zhang X,Chen X,Wang X,Yuan F,Zhou X

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening hematological condition associated with deficiency in ADAMTS13. Ocular manifestations associated with TTP are uncommon. CASE PRESENTATION:Here we report a case where a 44 year old female patient with a history of symptomatic anemia and cotton w...

journal_title：BMC ophthalmology

authors： Bandara AGNMK,Matthias AT

更新日期：2020-11-19 00:00:00

abstract：PURPOSE:To investigate the dynamic changes of hyperreflective foci (HF) in diabetic macular edema (DME) patients during the intravitreal Conbercept treatment in China. METHODS:DME Patients receiving intravitreal Conbercept (IVC) injections during the year 2016-2017 were retrospectively investigated. Thirteen patients ...

journal_title：BMC ophthalmology

authors： Liu S,Wang D,Chen F,Zhang X

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular pressure (IOP)-lowering medication change rates in patients newly treated with latanoprost or travoprost-...

journal_title：BMC ophthalmology

authors： Fain JM,Kotak S,Mardekian J,Bacharach J,Edward DP,Rauchman S,Brevetti T,Fox JL,Lovelace C

更新日期：2011-06-13 00:00:00

abstract：BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...

journal_title：BMC ophthalmology

authors： El-Assal K,Foulds J,Dobson S,Sanders R

更新日期：2015-12-07 00:00:00

abstract：BACKGROUND:Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogenic factor of this disease. Proteasome is an intracellular multi-subunit protease complex that degrade...

journal_title：BMC ophthalmology

authors： Aletras AJ,Trilivas I,Christopoulou ME,Drakouli S,Georgakopoulos CD,Pharmakakis N

更新日期：2018-12-18 00:00:00

abstract：BACKGROUND:To report the prevalence of ocular abnormalities and investigate visual acuity in a large cohort of retinitis pigmentosa (RP) patients in Western China. METHODS:The medical records and ophthalmic examination reports of 2127 eyes of 1065 RP patients at one eye hospital were retrospectively reviewed to determ...

journal_title：BMC ophthalmology

authors： Tan L,Long Y,Li Z,Ying X,Ren J,Sun C,Meng X,Li S

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:To report a case of multiple evanescent white dot syndrome (MEWDS) following simultaneous rabies vaccination. CASE PRESENTATION:Review of the clinical, laboratory, photographic, optical coherence tomographic (OCT), fundus autofluorescent, angiographic, electrophysiologic, and perimetric records of a patient...

journal_title：BMC ophthalmology

authors： Yang JS,Chen CL,Hu YZ,Zeng R

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:To report a rare case of bilateral Purtscher-like retinopathy in a Chinese female patient with dermatomyositis. CASE PRESENTATION:An 18-year-old woman with lower extremity muscle weakness was admitted due to decreased vision of both eyes for two weeks. Ophthalmic examination revealed violaceous eruption on ...

journal_title：BMC ophthalmology

authors： Yan Y,Shen X

更新日期：2013-07-24 00:00:00

abstract：BACKGROUND:Bone marrow transplantation retinopathy is a rare condition affecting the posterior pole. The purpose of this case report is to highlight the possible risk factors and clinical features. CASE PRESENTATION:A 19y old male with relapsed and refractory acute lymphoblastic leukaemia was admitted under haematolog...

journal_title：BMC ophthalmology

authors： Butt F,McKibbin M

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND:Previous studies described cases of Ocriplasmin injections in patients with vitreo-macular traction and reduced central visual acuity. We describe the first case of a patient with 20/20 visual acuity and vitreo-macular traction treated with Ocriplasmin, and, for the first time in literature, we evaluated the...

journal_title：BMC ophthalmology

authors： Rossi S,Orrico A,Melillo P,Testa F,Simonelli F,Della Corte M

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist called cryosim-3 (C3, 1-diisopropylphosphorylnonane) which selectively activates TRPM8 (linked to co...

journal_title：BMC ophthalmology

authors： Yang JM,Li F,Liu Q,Rüedi M,Wei ET,Lentsman M,Lee HS,Choi W,Kim SJ,Yoon KC

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:To evaluate the relationships between Reichert Ocular Response Analyzer (ORA) parameters corneal hysteresis (CH) and corneal response factor (CRF) and ocular dimensions, age and intraocular pressure. METHODS:Two hundred and twelve eyes of 212 participants with no ocular pathology had CH and CRF measured wit...

journal_title：BMC ophthalmology

authors： Kotecha A,Russell RA,Sinapis A,Pourjavan S,Sinapis D,Garway-Heath DF

更新日期：2014-01-30 00:00:00

abstract：BACKGROUND:We report the enhanced depth imaging optical coherence tomography (EDI-OCT) characteristics and variations in a patient with subretinal fluid secondary to a carotid cavernous fistula. CASE PRESENTATION:A 59-year-old man presented with blurred vision in his right eye. Venous congestion of the epiescleral and...

journal_title：BMC ophthalmology

authors： Rey A,Castillo L,Dyrda A,Maseras X,Jürgens I

更新日期：2016-05-26 00:00:00

abstract：BACKGROUND:To explore the molecular genetic cause of a four-generation autosomal dominant congenital cataract family in China. METHODS:Targeted region sequencing was performed to screen for the potential mutation, and Sanger sequencing was used to confirm the mutation. The homology model was constructed to identify th...

journal_title：BMC ophthalmology

authors： Li D,Xu C,Huang D,Guo R,Ji J,Liu W

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:There is no generally accepted medical or surgical treatment to stop the progressive course of retinitis pigmentosa. Previous studies have suggested lutein as a potential treatment with positive effects on macular pigment density. The objective of this study was to examine the effect of lutein supplementatio...

journal_title：BMC ophthalmology

authors： Bahrami H,Melia M,Dagnelie G

更新日期：2006-06-07 00:00:00

abstract：BACKGROUND:We present a case of post-traumatic endophthalmitis with relatively good prognosis caused by Gordonia sputi, which, to our knowledge is the first case in the literature. CASE PRESENTATION:A 24 year old man, who underwent an intraocular foreign body extraction half a month before presentation in the left eye...

journal_title：BMC ophthalmology

authors： Fang W,Li J,Cui HS,Jin X,Zhai J,Dai Y,Li Y

更新日期：2017-10-11 00:00:00

abstract：:Ophthalmologists and researchers in ophthalmology understand what a rapidly evolving field ophthalmology is, and that to conduct good research it is essential to use the latest and best methods. In outcomes research, one modern initiative has been to conduct holistic measurement of outcomes inclusive of the patient's ...

journal_title：BMC ophthalmology

authors： Pesudovs K

更新日期：2006-06-15 00:00:00

abstract：BACKGROUND:Ocular signs of Fabry disease can be seen in the first decade of life. METHODS:We examined the occurrence of ocular signs in 232 paediatric patients in the Fabry Outcome Survey (FOS) international registry and looked for relationships between the presence of eye findings and disease severity as measured by ...

journal_title：BMC ophthalmology

authors： Kalkum G,Pitz S,Karabul N,Beck M,Pintos-Morell G,Parini R,Rohrbach M,Bizjajeva S,Ramaswami U

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:With the diabetes mellitus (DM) prevalence increasing annually, the human grading of retinal images to evaluate DR has posed a substantial burden worldwide. SmartEye is a recently developed fundus image processing and analysis system with lesion quantification function for DR screening. It is sensitive to th...

journal_title：BMC ophthalmology

authors： Xu Y,Wang Y,Liu B,Tang L,Lv L,Ke X,Ling S,Lu L,Zou H

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:Retinal detachment is a disorder of the eye in which sensory retina separates from the retinal pigment epithelium (RPE) due to accumulation of fluid in subretinal space. Pharmacological stimulation of fluid reabsorption from subretinal space to choroid across the RPE has been suggested as a treatment strateg...

journal_title：BMC ophthalmology

authors： Iserovich P,Qin Q,Petrukhin K

更新日期：2011-11-15 00:00:00

abstract：BACKGROUND:Primary lacrimal sac melanoma is an extremely rare condition with fewer than 50 cases reported so far. Clinically, its symptoms resemble those of dacryocystitis, leading to frequent misdiagnosis. During diagnosis, imaging examination is often performed to differentiate tumors from inflammation. In this repor...

journal_title：BMC ophthalmology

authors： Shao JW,Yin JH,Xiang ST,He Q,Zhou H,Su W

更新日期：2020-05-14 00:00:00

abstract：BACKGROUND:Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS:Six focus group sessions were conducted at t...

journal_title：BMC ophthalmology

authors： Yeo S,Tong L

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Adenovirus (Ad), associated with significant morbidity, has no topical treatment. A leading CTC compound (CTC-96), a Co(III) chelate, was found to have potent in vitro and in vivo antiviral efficacy against herpes viruses. In this study CTC-96 is being tested for possible anti-Adenovirus activity. METHODS:T...

journal_title：BMC ophthalmology

authors： Epstein SP,Pashinsky YY,Gershon D,Winicov I,Srivilasa C,Kristic KJ,Asbell PA

更新日期：2006-06-05 00:00:00

abstract：BACKGROUND:Monocular infantile blindness may be associated with bilateral horizontal nystagmus, a subtype of fusion maldevelopment nystagmus syndrome (FMNS). Patients often adopt a significant anomalous head posture (AHP) towards the fixing eye in order to dampen the nystagmus. This clinical entity has also been report...

journal_title：BMC ophthalmology

authors： Sturm V,Hejcmanova M,Landau K

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...

journal_title：BMC ophthalmology

authors： Fraccaro P,Nicolo M,Bonetto M,Giacomini M,Weller P,Traverso CE,Prosperi M,OSullivan D

更新日期：2015-01-27 00:00:00

abstract：BACKGROUND:To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model. METHODS:Pharmacokinetic analyses determined the corticosteroid con...

journal_title：BMC ophthalmology

authors： Araki-Sasaki K,Katsuta O,Mano H,Nagano T,Nakamura M

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Cataract surgery in diabetics is more technically challenging due to a number of factors including poor intraoperative pupil dilation and a higher risk of vision threatening complications. This study evaluates the safety and efficacy of an intracameral combination of 2 mydriatics and 1 anesthetic (ICMA, Mydr...

journal_title：BMC ophthalmology

authors： Labetoulle M,Behndig A,Tassignon MJ,Nuijts R,Mencucci R,Güell JL,Pleyer U,Szaflik J,Rosen P,Bérard A,Chiambaretta F,Cochener-Lamard B,Intracameral Mydrane (ICMA), Ethics Group.

更新日期：2020-03-03 00:00:00