Abstract:
BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening hematological condition associated with deficiency in ADAMTS13. Ocular manifestations associated with TTP are uncommon. CASE PRESENTATION:Here we report a case where a 44 year old female patient with a history of symptomatic anemia and cotton wool appearance in retina during ophthalmological examination and subsequently, she was diagnosed to have TTP. The proper management with Therapeutic Plasma Exchange (TPE) and IV methylprednisolone improved the condition of the patient markedly. CONCLUSION:It concludes that even though the presence of cotton wool appearance in retina is a nonspecific sign it needs to be properly evaluated as there can be underlying serious illnesses as in our patient. Cotton wool spots can be an early sign of underlying retinal compromise and it should be identified early.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Bandara AGNMK,Matthias ATdoi
10.1186/s12886-020-01719-zsubject
Has Abstractpub_date
2020-11-19 00:00:00pages
456issue
1issn
1471-2415pii
10.1186/s12886-020-01719-zjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:To evaluate the correlation between visual acuity improvement and vision-related QOL after ranibizumab treatment in Japanese patients with AMD. METHODS:In this one-year prospective, interventional, open-label, multicenter study involving four sites, patients with neovascular AMD were enrolled and observed f...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-021-01816-7
更新日期:2021-01-23 00:00:00
abstract:BACKGROUND:Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine green angiography (IA) has shown anti-vascular endothelial growth factor (VEGF) agents and/or photody...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0952-6
更新日期:2018-11-03 00:00:00
abstract:BACKGROUND:To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery. METHODS:A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) aft...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0749-7
更新日期:2018-03-23 00:00:00
abstract:BACKGROUND:Older drivers have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all age groups. Contrast sensitivity impairment is common in older adults. The purpose of this study is to examine whether parameters from the photopic and mesopic contrast sensitivity functions (CSF) ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12886-020-1331-7
更新日期:2020-02-04 00:00:00
abstract:BACKGROUND:To report a case of branch retinal artery occlusion (BRAO) secondary to high-altitude exposure and diabetic retinopathy (DR), and to characterize the retinal changes before and after hyperbaric oxygen (HBO) treatment. CASE PRESENTATION:We present a case of a 42-year-old man with DR who travelled to Tibet (i...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01563-1
更新日期:2020-07-11 00:00:00
abstract:BACKGROUND:To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy. CASE PRESENTATION:A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. Sh...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1063-8
更新日期:2019-02-14 00:00:00
abstract:BACKGROUND:This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. METHODS:In this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0503-6
更新日期:2017-07-04 00:00:00
abstract:BACKGROUND:The aim of the study is to investigate risk factors for future falls in subject with primary open angle glaucoma (POAG). METHODS:All participants answered the following question at their baseline ophthalmic examination: Have you had any falls in the last year? (Yes/No). All study participants answered the s...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0613-1
更新日期:2017-11-25 00:00:00
abstract:BACKGROUND:Previous analyses of real-life data indicated that injection frequency and health care costs did not differ for anti-VEGF treatment with aflibercept and ranibizumab. The objective of this study was to investigate whether this finding persisted when analysing a longer time period after licensing. METHODS:Ret...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0617-x
更新日期:2017-12-04 00:00:00
abstract:BACKGROUND:To evaluate the prognosis of Chinese patients with lacrimal gland adenoid cystic carcinoma treated with eye-sparing surgery and adjuvant multimodal therapy. METHODS:The study included 24 consecutive patients with lacrimal gland adenoid cystic carcinoma treated at the Ninth People's Hospital of Shanghai from...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1110-5
更新日期:2019-06-08 00:00:00
abstract:BACKGROUND:To understand the clinical and economic outcomes of treatments for managing complications of ischemic central retinal vein occlusion (iCRVO). METHODS:We conducted a systematic literature review by searching multiple databases and ophthalmology conferences from 2004 to 2015. Studies published in English lang...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-016-0282-5
更新日期:2016-07-11 00:00:00
abstract:BACKGROUND:Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is to identify association between socioeconomic status and the visual impairments caused by primary glaucoma in Korea. METHODS:This study is based on a ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0551-y
更新日期:2017-08-23 00:00:00
abstract:BACKGROUND:The eMERGE (electronic MEdical Records and Genomics) network, funded by the National Human Genome Research Institute, is a national consortium formed to develop, disseminate, and apply approaches to research that combine DNA biorepositories with electronic health record (EHR) systems for large-scale, high-th...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-32
更新日期:2011-11-11 00:00:00
abstract:BACKGROUND:To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. METHODS:This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. I...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0719-0
更新日期:2018-02-20 00:00:00
abstract:BACKGROUND:Despite the progress in vitreoretinal surgery and the importance of silicone oil as an adjunct for the treatment of complex forms of retinal detachment, controversy still surrounds the issue of selecting the proper oil viscosity for clinical use. Herein, we evaluate the outcomes of retinal detachment (RD) su...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-21
更新日期:2006-05-31 00:00:00
abstract:BACKGROUND:Iridoschisis is a rare condition that is characterized by the separation of the iris stroma into layers, with portions of the anterior layer floating freely in the aqueous humour. Here, we report three cases of iridoschisis that were complicated by either a cataract or glaucoma. Based on these cases, we spec...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-017-0418-2
更新日期:2017-03-14 00:00:00
abstract:BACKGROUND:Uncorrected refractive errors contribute enormously to the burden of avoidable visual impairment worldwide. There is a huge disparity in different parts of the globe in context to spectacle coverage for distance vision. This study was undertaken with objectives of determining prevalence of spectacle coverage...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1262-3
更新日期:2019-12-12 00:00:00
abstract:BACKGROUND:To investigate the 3-month postoperative performance and safety after implantation of a trifocal intraocular lens (IOL) in a Korean population. METHODS:This was a clinical, prospective, multicenter, single-arm study. Forty-four subjects (88 eyes) with bilateral cataract with expected postoperative corneal a...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01549-z
更新日期:2020-07-15 00:00:00
abstract:PURPOSE:Outcome measurements currently used in chronic uveitis care fail to cover the full patient perspective. The aim of this study is to develop a conceptual model of the factors that adult patients with chronic uveitis consider to be important when evaluating the impact of their disease and treatment. METHODS:A qu...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01388-y
更新日期:2020-03-30 00:00:00
abstract:BACKGROUND:we conducted our meta-analysis of published studies to assess existing evidence about the efficacy and safety of vitrectomy with ILM peeling vs. that of vitrectomy with no ILM peeling for Macular hole-induced retinal detachment. METHODS:Databases, including Pubmed, Cochrane Library, Ovid, Web of Science, Wa...
journal_title:BMC ophthalmology
pub_type: 杂志文章,meta分析
doi:10.1186/s12886-015-0048-5
更新日期:2015-06-20 00:00:00
abstract:BACKGROUND:The aim of this study was to compare superior and temporal clear corneal incisions of uneventful phacoemulsification and in-the-bag intraocular lens implantation on intraocular pressure control and the bleb morphology in eyes that have undergone previous successful trabeculectomy. METHODS:In this Prospectiv...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12886-017-0500-9
更新日期:2017-06-26 00:00:00
abstract:BACKGROUND:Central Serous Chorioretinopathy (CSC) has been previously reported as an infrequent complication of pregnancy that usually resolves spontaneously after delivery, with minimal or no sequel. We report a case of a severe form of CSC in an uncomplicated pregnancy with extensive subfoveal exudates and severe per...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0169-x
更新日期:2015-12-22 00:00:00
abstract:BACKGROUND:To compare the efficacy of phacoemulsification (PKE) combined with nonpenetrating deep sclerectomy (NPDS) with mitomycin C (MMC) versus XEN® gel stent with MMC. METHODS:In this nonrandomized, retrospective, comparative, single-center pilot study, 105 consecutive eyes of 75 patients with uncontrolled primary...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01492-z
更新日期:2020-06-16 00:00:00
abstract:BACKGROUND:Retinal artery occlusion caused by myxoma is relatively rare. There are several points that should be taken into consideration to avoid overlooking this disorder. CASE PRESENTATION:This case report describes a 43-year-old woman with sudden vision loss in her left eye for 20 days after single sudden syncope....
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-164
更新日期:2014-12-23 00:00:00
abstract:BACKGROUND:Cavernous carotid aneurysm (CCA) represents 2-9% of all intracranial aneurysms and 15% of internal carotid artery (ICA) aneurysms; additionally, giant aneurysms are those aneurysms that are > 25 mm in size. Bilateral CCAs account for 11-29% of patients and are commonly associated with structural weaknesses i...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0687-4
更新日期:2018-02-02 00:00:00
abstract:BACKGROUND:To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play an important role in the pathophysiology of this case. CASE PRESENTATION:A 9 year-old male with ac...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-30
更新日期:2011-11-02 00:00:00
abstract:BACKGROUND:Ocular signs of Fabry disease can be seen in the first decade of life. METHODS:We examined the occurrence of ocular signs in 232 paediatric patients in the Fabry Outcome Survey (FOS) international registry and looked for relationships between the presence of eye findings and disease severity as measured by ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0374-2
更新日期:2016-11-16 00:00:00
abstract:BACKGROUND:Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0883-2
更新日期:2018-09-03 00:00:00
abstract:BACKGROUND:The present study sought to introduce clinical characteristics and stepwise surgical strategies of isolated complete cryptophthalmos, a rare, congenital ocular anomaly. CASE PRESENTATION:Retrospective, noncomparative, clinical study. Six patients with isolated complete cryptophthalmos were diagnosed at the ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1170-6
更新日期:2019-07-31 00:00:00
abstract:BACKGROUND:This multicentre, retro-prospective real-world study evaluated the visual, refractive and safety outcomes of a monofocal lens 1 year after implantation in cataract patients with or without pre-existing ocular pathologies. METHODS:Records from 4 centres in Germany and Sweden were reviewed to select eyes with...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01493-y
更新日期:2020-06-11 00:00:00