Abstract:
BACKGROUND:This multicentre, retro-prospective real-world study evaluated the visual, refractive and safety outcomes of a monofocal lens 1 year after implantation in cataract patients with or without pre-existing ocular pathologies. METHODS:Records from 4 centres in Germany and Sweden were reviewed to select eyes with aged-related cataracts, having undergone crystalline lens extraction by phacoemulsification and implantation of a CT ASPHINA 409 IOL. Preoperative, 1-month and 3-month postoperative data was collected retrospectively. In addition, included patients attended a prospective visit 12 months or later after surgery. The examination included: monocular uncorrected (UDVA) and corrected distance visual acuity (CDVA), subjective refraction, slit-lamp examination, optical biometry, intraocular pressure (IOP), endothelial cell count and postoperative complications. RESULTS:282 eyes, including 94 with pre-existing ocular pathologies, were analysed. Twelve months after the surgery, 95% of eyes achieved monocular CDVA equal or better than 0.3 logMAR, mean postoperative CDVA was 0.06 ± 0.17 logMAR, and mean UDVA 0.31 ± 0.29 logMAR. Visual acuity outcomes were better in eyes with no pre-existing ocular pathologies, but both groups showed a statistically significant improvement after surgery compared with preoperative values (p ≤ 0.002). The mean sphere and spherical equivalent values also improved significantly postoperatively (p = 0.003). Overall, 62.1% of eyes had spherical equivalent within ±0.5 D and 80.9% within ±1.0 D. The IOL was stable in the capsular bag as demonstrated by tilt and decentration measurements. IOP, corneal status, and endothelial cell count values were in the normal range. Nd:YAG treatment was performed on 9.9% of the eyes. CONCLUSION:The implantation of the monofocal CT ASPHINA 409 IOL was beneficial to restore vision in eyes with or without concomitant ocular pathology such as macular degeneration, glaucoma, Sicca syndrome, epiretinal membrane, cornea guttata, or amblyopia. Good to excellent long-term visual and refractive outcomes, and a low rate of complications in both healthy and pathological eyes were found 12 months after the surgery. TRIAL REGISTRATION:Trial registered on under the identification NCT03145103 (date of registration 9 May 2017).
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Johansson B,Daniel ACS,Herbers C,Gerl M,Kretz FTAdoi
10.1186/s12886-020-01493-ysubject
Has Abstractpub_date
2020-06-11 00:00:00pages
224issue
1issn
1471-2415pii
10.1186/s12886-020-01493-yjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:To assess the precision and agreement of measurements of higher order aberrations (HOAs) obtained with a ray tracing aberrometer (iTrace) and a Hartmann-Shack aberrometer (Topcon KR-1 W). METHODS:Prospective evaluation of the diagnostic test. Data from the right eyes of 92 normal subjects obtained using the...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0683-8
更新日期:2018-01-27 00:00:00
abstract:BACKGROUND:To report the successful treatment of ocular toxoplasmosis and present the use of multimodal imaging to describe the changes in ocular toxoplasmic lesions subsequent to treatment. CASE PRESENTATION:A 73-year-old female visited the clinic with decreased visual acuity in the left eye. Fundus examination showe...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1209-8
更新日期:2019-09-05 00:00:00
abstract:BACKGROUND:The performance of glaucoma diagnostic systems could be conceivably improved by the integration of functional and structural test measurements that provide relevant and complementary information for reaching a diagnosis. The purpose of this study was to investigate the performance of data fusion methods and ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-20
更新日期:2011-08-04 00:00:00
abstract:BACKGROUND:Patient education materials should be written at a level that is understandable for patients with low health literacy. The aims of this study are (1) to review the literature on readability of ophthalmic patient education materials and (2) to evaluate and revise our institution's patient education materials ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-016-0315-0
更新日期:2016-08-03 00:00:00
abstract:BACKGROUND:To report a case of branch retinal artery occlusion (BRAO) secondary to high-altitude exposure and diabetic retinopathy (DR), and to characterize the retinal changes before and after hyperbaric oxygen (HBO) treatment. CASE PRESENTATION:We present a case of a 42-year-old man with DR who travelled to Tibet (i...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01563-1
更新日期:2020-07-11 00:00:00
abstract:BACKGROUND:Adenovirus (Ad), associated with significant morbidity, has no topical treatment. A leading CTC compound (CTC-96), a Co(III) chelate, was found to have potent in vitro and in vivo antiviral efficacy against herpes viruses. In this study CTC-96 is being tested for possible anti-Adenovirus activity. METHODS:T...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-22
更新日期:2006-06-05 00:00:00
abstract:BACKGROUND:Docetaxel is a chemotherapeutic agent of the taxane class of drugs for the treatment of breast cancer. We present a female patient who noted decreased vision after docetaxel treatment. CASE PRESENTATION:A 45-year-old female patient received docetaxel treatment after resection of a breast carcinoma. Fundusco...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0020-4
更新日期:2015-03-29 00:00:00
abstract:BACKGROUND:Nonarteritic ischemic optic neuropathy affects the anterior portion of the optic nerve and is characterized by sudden, painless visual loss. The affected eye has a relative afferent pupillary defect. The typical funduscopic appearance includes optic disc edema, with associated nerve fiber layer hemorrhage. R...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-32
更新日期:2006-10-11 00:00:00
abstract:BACKGROUND:Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implants and anti-vascular endothelial growth factor (VEGF). The goal of this study is to compare the effec...
journal_title:BMC ophthalmology
pub_type: 杂志文章,meta分析
doi:10.1186/s12886-018-1016-7
更新日期:2019-01-08 00:00:00
abstract:BACKGROUND:To report atypical features on Spectral domain optical coherence tomography (SD-OCT) in a case of non-familial pure adult nanophthalmos. CASE PRESENTATION:A 39 year old male hyperope was found to have biometric and fundus findings typical of nanophthalmos. The additional atypical features included serous pi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-12-12
更新日期:2012-06-06 00:00:00
abstract:BACKGROUND:The eMERGE (electronic MEdical Records and Genomics) network, funded by the National Human Genome Research Institute, is a national consortium formed to develop, disseminate, and apply approaches to research that combine DNA biorepositories with electronic health record (EHR) systems for large-scale, high-th...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-32
更新日期:2011-11-11 00:00:00
abstract:BACKGROUND:To evaluate the retinal function before and soon after an intravitreal injection of an anti-vascular endothelial growth factor (anti-VEGF) agents. METHODS:Seventy-nine eyes of 79 patients that were treated by an intravitreal injection of an anti-VEGF agent for age-related macular degeneration (AMD), diabeti...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1129-7
更新日期:2019-06-17 00:00:00
abstract:BACKGROUND:Since the normative value of the retinal macular thickness is undocumented in the Middle East, the aim of this work is to assess the normative values of the macular thickness in healthy eyes in a Middle Eastern population and its relationship with age, sex, and laterality. METHODS:One hundred sixteen indivi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01391-3
更新日期:2020-04-07 00:00:00
abstract:BACKGROUND:Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine green angiography (IA) has shown anti-vascular endothelial growth factor (VEGF) agents and/or photody...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0952-6
更新日期:2018-11-03 00:00:00
abstract:BACKGROUND:The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS:Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Departme...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0370-6
更新日期:2016-10-29 00:00:00
abstract:BACKGROUND:To screen for visual impairment in Malaysian preschool children. METHODS:Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs ste...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-16
更新日期:2013-04-19 00:00:00
abstract:BACKGROUND:The presence of an intraocular cilium is very rare and the response of the eye to the cilium is variable. We present the case of a patient with a cilium found in the vitreous cavity during vitrectomy for rhegmatogenous retinal detachment 40 years following penetrating eye injury. To our knowledge, this is th...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0010-6
更新日期:2015-03-12 00:00:00
abstract:BACKGROUND:To understand which irregular corneal parameters determine the visual quality in keratoconus subjects. METHODS:The cross-sectional study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Amsler-Krumeich classification. We obtained measurements in two ways: (a) by project...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01737-x
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:To understand the clinical and economic outcomes of treatments for managing complications of ischemic central retinal vein occlusion (iCRVO). METHODS:We conducted a systematic literature review by searching multiple databases and ophthalmology conferences from 2004 to 2015. Studies published in English lang...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-016-0282-5
更新日期:2016-07-11 00:00:00
abstract:BACKGROUND:Suture exposure remains to be a potential problem of transscleral fixated posterior chamber intraocular lens (PCIOL). We report a modified technique to minimize the risk of suture exposure for the transscleral fixation of PCIOL. METHODS:The modified surgical technique is as following: at first, two 3 mm × 4...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0118-8
更新日期:2015-10-02 00:00:00
abstract:BACKGROUND:Classification of optical coherence tomography (OCT) images can be achieved with high accuracy using classical convolution neural networks (CNN), a commonly used deep learning network for computer-aided diagnosis. Classical CNN has often been criticized for suppressing positional relations in a pooling layer...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01382-4
更新日期:2020-03-19 00:00:00
abstract:BACKGROUND:Although the association between metabolic syndrome and intraocular pressure is well known, the relationship between the intraocular pressure and different combination of the components of metabolic syndrome has not been actively researched yet. The study aimed to investigate the relationship between the int...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0263-8
更新日期:2016-06-06 00:00:00
abstract:BACKGROUND:The case describes a rare entity. Most cases of IOL dislocation are associated with surgical trauma or preexisting zonulopathy. This patient presents IOL dislocation following routine exam, suggesting the need of careful evaluation of zonular integrity on pseudopahkic patients. METHODS:Patient is a 65 year ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-1327-3
更新日期:2020-01-30 00:00:00
abstract:BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-15-10
更新日期:2015-01-27 00:00:00
abstract:BACKGROUND:Central Serous Chorioretinopathy (CSC) has been previously reported as an infrequent complication of pregnancy that usually resolves spontaneously after delivery, with minimal or no sequel. We report a case of a severe form of CSC in an uncomplicated pregnancy with extensive subfoveal exudates and severe per...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0169-x
更新日期:2015-12-22 00:00:00
abstract:BACKGROUND:To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand. METHODS:A prospective, multi-centre, observational study was conducted among eight hospitals in their ophthalmology outpatient depart...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12886-019-1086-1
更新日期:2019-03-29 00:00:00
abstract:BACKGROUND:Dolosigranulum pigrum is a commensal inhabitant of the upper respiratory tract suspected to be responsible for ocular infections but no well-described case of D. pigrum corneal infection has been reported. Herein culture and PCR-sequencing-based investigations of corneal scraping specimens confirmed D. pigru...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-31
更新日期:2013-07-10 00:00:00
abstract:BACKGROUND:Goldenhar Syndrome is characterized by malformations of multiple anatomical districts. Between these, bulbar dermoids are common and represent a significant clinical problem as they can affect both ocular function and aesthetic comfort.Histologic characterization of dermoids has been extensively performed; h...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-55
更新日期:2013-10-16 00:00:00
abstract:BACKGROUND:To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy. CASE PRESENTATION:A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. Sh...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1063-8
更新日期:2019-02-14 00:00:00
abstract:BACKGROUND:Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogenic factor of this disease. Proteasome is an intracellular multi-subunit protease complex that degrade...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0987-8
更新日期:2018-12-18 00:00:00