Abstract:
BACKGROUND:Primary lacrimal sac melanoma is an extremely rare condition with fewer than 50 cases reported so far. Clinically, its symptoms resemble those of dacryocystitis, leading to frequent misdiagnosis. During diagnosis, imaging examination is often performed to differentiate tumors from inflammation. In this report, we present a case of primary lacrimal sac melanoma and summarize the CT and MRI characteristics of lacrimal sac melanoma. CASE PRESENTATION:We report a 50-year-old female patient who had undergone a dacryocystectomy for the left lacrimal sac mass. Postoperative pathological examination confirmed the presence of primary malignant melanoma. Three months later, a lump in the lacrimal sac area was found. The patient underwent CT and MR examinations. CT scan demonstrated a partially well-defined soft mass in the fossa of left lacrimal sac extending into the nasolacrimal duct and anterior ethmoid sinus. MRI revealed an intermediate signal intensity on T1 and iso-or hyper-signal on T2 weighted images. Histopathological examination on biopsy confirmed recurrence of primary lacrimal sac melanoma. DISCUSSION AND CONCLUSIONS:None has described the CT and MR findings of primary lacrimal sac melanoma so far. Typically, MR images show hyperintensity signal on T1-weighted images and hypointense signal on T2-weighted images owing to the paramagnetic properties of melanin. In contrast to previous reports and the present case, most cases do not present these typical signals. Thus, reporting such radiological findings is important to create awareness on variant images of primary lacrimal sac melanoma. This will reduce misdiagnosis and mistreatment.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Shao JW,Yin JH,Xiang ST,He Q,Zhou H,Su Wdoi
10.1186/s12886-020-01356-6subject
Has Abstractpub_date
2020-05-14 00:00:00pages
191issue
1issn
1471-2415pii
10.1186/s12886-020-01356-6journal_volume
20pub_type
杂志文章abstract:BACKGROUND:To understand which irregular corneal parameters determine the visual quality in keratoconus subjects. METHODS:The cross-sectional study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Amsler-Krumeich classification. We obtained measurements in two ways: (a) by project...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01737-x
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the interocular differences in the peripapillary retinal nerve fibre layer (RNFL), peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) in healthy adults with isometropia, using enhanced depth imaging optical coherence tomography (EDI SD-OCT)...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0361-7
更新日期:2016-10-19 00:00:00
abstract:BACKGROUND:Recently, instruments for the measurement of wavefront aberration in the living human eye have been widely available for clinical applications. Despite the extensive background experience on wavefront sensing for research purposes, the information derived from such instrumentation in a clinical setting shoul...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-4-1
更新日期:2004-02-11 00:00:00
abstract:BACKGROUND:A description of the diagnostic features of Miller Fisher syndrome. CASE PRESENTATION:The clinical presentation, investigation, and subsequent progress of our patient with clinical unilateral external ophthalmoplegia. CONCLUSION:Our case demonstrates the presentation of clinical unilateral external ophthal...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-7-7
更新日期:2007-04-17 00:00:00
abstract:BACKGROUND:To analyse the associated factors, diagnosis, clinical manifestations and therapeutic effects of Acanthamoeba keratitis at a tertiary ophthalmic centre in Southern China. METHODS:A retrospective clinical study was performed in fifteen patients who were admitted to Zhongshan Ophthalmic Centre (ZOC) from Janu...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0571-7
更新日期:2017-10-02 00:00:00
abstract:BACKGROUND:To evaluate the efficacy of triple therapy consisting of single-session photodynamic therapy (PDT), intravitreal bevacizumab (IVB) and intravitreal triamcinolone (IVT) as initial pulse therapy followed by repeat intravitreal bevacizumab injections for maintenance treatment in neovascular age-related macular ...
journal_title:BMC ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2415-7-10
更新日期:2007-06-07 00:00:00
abstract:BACKGROUND:This case report describes a patient with chronic unilateral chemosis, likely due to treatment with amlodipine besylate. CASE PRESENTATION:A 52-year-old man visited the clinic with symptoms of foreign body sensation and puffiness in his right eye, which had persisted for 4 months. There were no other sympto...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-124
更新日期:2014-10-21 00:00:00
abstract:BACKGROUND:Bone marrow transplantation retinopathy is a rare condition affecting the posterior pole. The purpose of this case report is to highlight the possible risk factors and clinical features. CASE PRESENTATION:A 19y old male with relapsed and refractory acute lymphoblastic leukaemia was admitted under haematolog...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0855-6
更新日期:2018-09-14 00:00:00
abstract:BACKGROUND:To examine the clinical features of acute acquired comitant esotropia (AACE) and to evaluate the clinical effectiveness of a single injection of botulinum toxin type A (BTXA) on binocular visual function (BVF). METHODS:This retrospective, observational case series study enrolled patients with AACE examined ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01739-9
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:A patient's health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark. METHODS:This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1191-1
更新日期:2019-08-08 00:00:00
abstract:BACKGROUND:Although most patients with visual impairment due to corneal diseases can be treated successfully with surgery, some require visual rehabilitation to restore reading ability. To evaluate the best LVAs especially in terms of reading speed and characterize this specific patient group we performed a prospective...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01436-7
更新日期:2020-05-06 00:00:00
abstract:BACKGROUND:To compare the efficacy of phacoemulsification (PKE) combined with nonpenetrating deep sclerectomy (NPDS) with mitomycin C (MMC) versus XEN® gel stent with MMC. METHODS:In this nonrandomized, retrospective, comparative, single-center pilot study, 105 consecutive eyes of 75 patients with uncontrolled primary...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01492-z
更新日期:2020-06-16 00:00:00
abstract:BACKGROUND:Docetaxel is a chemotherapeutic agent of the taxane class of drugs for the treatment of breast cancer. We present a female patient who noted decreased vision after docetaxel treatment. CASE PRESENTATION:A 45-year-old female patient received docetaxel treatment after resection of a breast carcinoma. Fundusco...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0020-4
更新日期:2015-03-29 00:00:00
abstract:BACKGROUND:The ocular presentation of Castleman's disease (CD)-associated paraneoplastic pemphigus (PNP) has rarely been reported. In this report, we describe a young patient with CD-associated PNP who had recurrent corneal ulceration in addition to cicatrizing conjunctivitis. CASE PRESENTATION:We describe a case of 2...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0280-7
更新日期:2016-07-12 00:00:00
abstract:BACKGROUND:To determine the accuracy of the T2 formula as applied to highly myopic eyes, to compare the T2 formula to the SRK/T and Holladay 1 formulas, and to describe possible ways to improve the estimation of corneal height and prediction error in two settings, the Hadassah Hospital, Ophthalmology Department, Jerusa...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1226-7
更新日期:2019-11-12 00:00:00
abstract:BACKGROUND:Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine green angiography (IA) has shown anti-vascular endothelial growth factor (VEGF) agents and/or photody...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0952-6
更新日期:2018-11-03 00:00:00
abstract:BACKGROUND:Retinal detachment is a disorder of the eye in which sensory retina separates from the retinal pigment epithelium (RPE) due to accumulation of fluid in subretinal space. Pharmacological stimulation of fluid reabsorption from subretinal space to choroid across the RPE has been suggested as a treatment strateg...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-33
更新日期:2011-11-15 00:00:00
abstract:BACKGROUND:To compare the corneal high-order aberrations (HOAs), asphericity and regularity after Q-value guided laser in situ keratomileusis (LASIK) and laser epithelial keratomileusis (LASEK) in high myopic astigmatism. METHODS:In this retrospectively comparative study, we measured the corneal HOAs, asphericity indi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-12-15
更新日期:2012-06-18 00:00:00
abstract:BACKGROUND:The use of capsular tension ring (CTR) implantation to treat cataract patients with weak zonules is still controversial. The aim of this study was to examine the effects of CTR implantation on capsular stability after phacoemulsification in patients with weak zonules, especially patients who have undergone p...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01772-8
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:To evaluate the efficacy and safety of intravitreal conbercept (KH902) as the primary treatment of choroidal neovascularization secondary to punctate inner choroidopathy. METHODS:This study was a retrospective, consecutive, observational case series. We reviewed medical records of 16 eyes (16 patients) with...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0481-8
更新日期:2017-06-12 00:00:00
abstract:BACKGROUND:Ocular coloboma is an excavation of ocular structures that occurs due to abnormal fusion of the embryonic optic fissure. Further, cleft lip/palate (CL/P), a congenital midline abnormality, is caused by a defect in the fusion of the frontonasal, maxillary, and mandibular prominences. No study has reported the...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01696-3
更新日期:2020-10-19 00:00:00
abstract:BACKGROUND:The aim of this study was to compare superior and temporal clear corneal incisions of uneventful phacoemulsification and in-the-bag intraocular lens implantation on intraocular pressure control and the bleb morphology in eyes that have undergone previous successful trabeculectomy. METHODS:In this Prospectiv...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12886-017-0500-9
更新日期:2017-06-26 00:00:00
abstract:BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0161-5
更新日期:2015-12-07 00:00:00
abstract:BACKGROUND:Congenital cataract (CC) is a significant cause of lifelong visual loss, and its genetic diagnosis is challenging due to marked genetic heterogeneity. The purpose of this article is to report the genetic findings in sporadic and familial CC patients. METHODS:Patients (n = 53) who were clinically diagnosed w...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01567-x
更新日期:2020-09-03 00:00:00
abstract:BACKGROUND:The aim of the study is to investigate risk factors for future falls in subject with primary open angle glaucoma (POAG). METHODS:All participants answered the following question at their baseline ophthalmic examination: Have you had any falls in the last year? (Yes/No). All study participants answered the s...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0613-1
更新日期:2017-11-25 00:00:00
abstract:BACKGROUND:To describe the spectral domain optical coherence tomography (SD-OCT) findings of a patient who developed pigmentary retinopathy following high-dose deferoxamine administration. CASE PRESENTATION:A 34-year-old man with thalassemia major complained of nyctalopia and decreased vision following high-dose intra...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-88
更新日期:2014-07-02 00:00:00
abstract:BACKGROUND:Despite the progress in vitreoretinal surgery and the importance of silicone oil as an adjunct for the treatment of complex forms of retinal detachment, controversy still surrounds the issue of selecting the proper oil viscosity for clinical use. Herein, we evaluate the outcomes of retinal detachment (RD) su...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-21
更新日期:2006-05-31 00:00:00
abstract:BACKGROUND:The Heimann-Bielschowsky phenomenon (HBP) is an underrecognized condition characterized by slow, pendular, vertical oscillations of the eye accompanying monocular vision loss. Hypotropic dissociated vertical deviation (DVD) is another rare condition induced by asymmetric visual input. This report documents a...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01502-0
更新日期:2020-06-26 00:00:00
abstract:BACKGROUND:Retinal artery occlusion caused by myxoma is relatively rare. There are several points that should be taken into consideration to avoid overlooking this disorder. CASE PRESENTATION:This case report describes a 43-year-old woman with sudden vision loss in her left eye for 20 days after single sudden syncope....
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-164
更新日期:2014-12-23 00:00:00
abstract:BACKGROUND:Endogenous endophthalmitis could lead to a devastating outcome without a prompt and appropriate management. We report a case of advanced endogenous Klebsiella pneumoniae endophthalmitis with extensive subretinal abscess that was successfully treated with a vitrectomy. CASE PRESENTATION:A systemically well 6...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0908-x
更新日期:2018-09-05 00:00:00