Abstract：
BACKGROUND:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening conditions that initially affect the skin and mucous membranes. The aim of this study was to compare the acute ocular manifestations between SJS and TEN. METHODS:The initial presenting ophthalmic records of patients with either SJS (<30% body surface area involvement) or TEN (> = 30% involvement), who were treated at one tertiary burn center in Hong Kong between 1999 and 2014, were retrospectively analyzed and compared. RESULTS:A total of 20 SJS and 12 TEN cases were included. All were drug-induced. The patient demographics and treatment received were comparable. Overall, 40% of SJS and 75% of TEN patients had acute ocular surface inflammation. When comparing the two groups, there was a significant difference in the number of cases with mild involvement (5% in SJS, 42% in TEN, p = 0.01), while no statistically significant differences were found (p > 0.05) comparing between the moderate (15% in SJS, 0% in TEN) and severe groups (20% in SJS, 33% in TEN). CONCLUSIONS:Ocular surface inflammation was common during the acute phase in both SJS and TEN. TEN had a significantly higher number of cases with mild ocular involvement when compared with SJS, but no significant difference between the number of moderate and severe cases between the two groups.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Chow LLW,Shih KC,Chan JCY,Lai JSM,Ng ALKdoi
10.1186/s12886-017-0464-9subject
Has Abstractpub_date
2017-05-12 00:00:00pages
65issue
1issn
1471-2415pii
10.1186/s12886-017-0464-9journal_volume
17pub_type
杂志文章abstract：BACKGROUND:Glial heterotopias are rare, benign, congenital, midline, non-teratomatous extracranial glial tissue. They may masquerade as encephalocoele or dermoid cyst and mostly present in nose. Herein, we present an unusual case of glial heterotopia of the orbit with unilateral blindness. CASE PRESENTATION:A 6 year-o...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-34
更新日期：2011-11-16 00:00:00
abstract：BACKGROUND:Proliferative retinopathy is an uncommon feature of Vogt Koyanagi Harada (VKH) disease which might indicate poor uveitis control in these patients. We aim to describe the clinical features and outcome of management of proliferative retinopathy in 2 patients with VKH. CASE PRESENTATION:19 and 33 years old fe...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01736-y
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Patient education materials should be written at a level that is understandable for patients with low health literacy. The aims of this study are (1) to review the literature on readability of ophthalmic patient education materials and (2) to evaluate and revise our institution's patient education materials ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-016-0315-0
更新日期：2016-08-03 00:00:00
abstract：BACKGROUND:To evaluate the efficacy, complications, and clinical characteristics, including the ocular toxicity, of intravitreal melphalan(IVM) treatment for vitreous seeding in Chinese retinoblastoma patients. METHODS:This was a retrospective, non-comparative analysis including 30 consecutive eyes of 23 patients with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1059-4
更新日期：2019-02-26 00:00:00
abstract：PURPOSE:Outcome measurements currently used in chronic uveitis care fail to cover the full patient perspective. The aim of this study is to develop a conceptual model of the factors that adult patients with chronic uveitis consider to be important when evaluating the impact of their disease and treatment. METHODS:A qu...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01388-y
更新日期：2020-03-30 00:00:00
abstract：BACKGROUND:Uncorrected refractive errors contribute enormously to the burden of avoidable visual impairment worldwide. There is a huge disparity in different parts of the globe in context to spectacle coverage for distance vision. This study was undertaken with objectives of determining prevalence of spectacle coverage...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1262-3
更新日期：2019-12-12 00:00:00
abstract：BACKGROUND:Acute acquired comitant esotropia (AACE) is a type of strabismus characterized by a sudden onset of large angle esotropia with diplopia, which often occurs in children after infancy, teenagers, and young adolescents. However, studies on the surgical outcomes of only adults are rare. The purpose of this artic...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01793-3
更新日期：2021-01-18 00:00:00
abstract：BACKGROUND:To investigate the accommodative loads change needed to maintain binocular fusion in patients with intermittent exotropia (IXT). METHODS:Seventeen consecutive patients with basic IXT and 15 normal controls were recruited. The WAM-5500 autorefractor (GrandSeiko, Fukuyama, Japan) was used to measure refractiv...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0260-y
更新日期：2016-06-07 00:00:00
abstract：BACKGROUND:This study sought to identify factors associated with retinal detachment and retreatment of aggressive posterior retinopathy of prematurity (APROP) initially treated with intravitreal ranibizumab (IVR) injection as well as the efficacy of IVR treatment. METHODS:This was a retrospective study. A total of 83 ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0815-1
更新日期：2018-06-26 00:00:00
abstract：BACKGROUND:This case report describes a patient with chronic unilateral chemosis, likely due to treatment with amlodipine besylate. CASE PRESENTATION:A 52-year-old man visited the clinic with symptoms of foreign body sensation and puffiness in his right eye, which had persisted for 4 months. There were no other sympto...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-124
更新日期：2014-10-21 00:00:00
abstract：BACKGROUND:To understand the clinical and economic outcomes of treatments for managing complications of ischemic central retinal vein occlusion (iCRVO). METHODS:We conducted a systematic literature review by searching multiple databases and ophthalmology conferences from 2004 to 2015. Studies published in English lang...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-016-0282-5
更新日期：2016-07-11 00:00:00
abstract：BACKGROUND:The gold standard treatments in amblyopia are penalizing therapies, such as patching or blurring vision with atropine that are aimed at forcing the use of the amblyopic eye. However, in the last years, new therapies are being developed and validated, such as dichoptic visual training, aimed at stimulating th...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0501-8
更新日期：2017-06-28 00:00:00
abstract：BACKGROUND:P66Shc is partially localised within the mitochondrial fraction. It is primarily related to the generation of mitochondrial reactive oxygen species and apoptosis. Based on previous studies, we hypothesize that in the retina, p66Shc may exist and affect the development of diabetic retinopathy. The purpose of ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0724-3
更新日期：2018-02-27 00:00:00
abstract：BACKGROUND:Adolescent KC is a special segment of the general KC population because an adolescents's eyes are still susceptible to blurred vision and optical defocus during the sensitive period of ocular and visual development. In the present study, we evaluated the ocular dimensions of 53 KC adolescents. METHODS:One h...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0713-6
更新日期：2018-02-13 00:00:00
abstract：BACKGROUND:This study compared the postoperative outcomes of 27-gauge (G) and 25-G vitrectomy performed for the treatment of idiopathic epiretinal membrane (ERM). METHODS:The study design was single center, retrospective, interventional case series. Two hundred consecutive eyes that underwent primary vitrectomy for ER...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0585-1
更新日期：2017-10-10 00:00:00
abstract：BACKGROUND:To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery. METHODS:A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) aft...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0749-7
更新日期：2018-03-23 00:00:00
abstract：BACKGROUND:To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play an important role in the pathophysiology of this case. CASE PRESENTATION:A 9 year-old male with ac...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-30
更新日期：2011-11-02 00:00:00
abstract：BACKGROUND:We explore and compare the advantages and disadvantages of different operating methods for a peripheral iridectomy (PI) for phakic posterior chamber implantable contact lens (ICL) implantation in patients with dark-brown irides. METHODS:Forty-six patients completed this prospective comparative study. Neodym...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0229-x
更新日期：2016-05-05 00:00:00
abstract：BACKGROUND:Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0883-2
更新日期：2018-09-03 00:00:00
abstract：BACKGROUND:This is the third reported case of a steatocystoma simplex in the lacrimal caruncle. CASE PRESENTATION:A 60-year-old male presented with a history of a slowly progressing mass in the right lacrimal caruncle since several years before his initial visit. At the first examination, a yellowish, relatively smoot...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0358-2
更新日期：2016-10-19 00:00:00
abstract：BACKGROUND:To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up. METHODS:The study included 62 eyes that underwent successful PPV with SF6 t...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1120-3
更新日期：2019-05-24 00:00:00
abstract：:Although the mechanism of dry eye disease is not clearly understood, it is certain that inflammation and the immune response play a major role in determining the health of the ocular surface in dry eye patients. Accurate ocular surface characterization during the early stages of dry eye disease is critical for success...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-015-0133-9
更新日期：2015-12-17 00:00:00
abstract：BACKGROUND:To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma. CASE PRESENTATION:We present a case of a 94-year-old male with choroidal melanoma of the right eye imaged with MRI and ocular ultrasound to aid in the detection of extrascleral exte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0990-0
更新日期：2018-12-12 00:00:00
abstract：BACKGROUND:To understand which irregular corneal parameters determine the visual quality in keratoconus subjects. METHODS:The cross-sectional study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Amsler-Krumeich classification. We obtained measurements in two ways: (a) by project...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01737-x
更新日期：2020-11-26 00:00:00
abstract：BACKGROUND:Reports of central corneal thickness (CCT) among glaucoma patients, particularly for pseudoexfoliative glaucoma (PXG) and Primary Angle Closure Glaucoma (PACG) are scarce in the Sub-Saharan African (SSA) population. The aim of this study is to evaluate CCT in black patients with newly diagnosed glaucoma and ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0334-x
更新日期：2016-08-31 00:00:00
abstract：BACKGROUND:The short-term effects of intravitreal ranibizumab (IVR) on diabetic macular edema (DME) remains unclear. We assessed the short-term effects of IVR on DME. METHODS:Eighteen eyes of 14 patients with DME were enrolled in this prospective interventional case series. After intravitreal ranibizumab was injected ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12886-017-0420-8
更新日期：2017-03-14 00:00:00
abstract：BACKGROUND:Glaucoma will undoubtedly impact on a person's ability to function as they go about their day-to-day life. The purpose of this study is to investigate the amount of published knowledge in quality of life (QoL) and visual disability studies for glaucoma, and make comparisons with similar research in other chr...
journal_title：BMC ophthalmology
pub_type： 信件
doi：10.1186/1471-2415-11-19
更新日期：2011-08-04 00:00:00
abstract：BACKGROUND:To assess the efficacy of the intravitreal (IVT) injection of Triamcinolone Acetonide (TA) as compared to posterior subtenon (SBT) capsule injection for the treatment of cystoid diabetic macular edema. METHODS:Fourteen patients with type II diabetes mellitus and on insulin treatment, presenting diffuse cyst...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-8-5
更新日期：2008-03-17 00:00:00
abstract：BACKGROUND:Currently, various types of toric intraocular lenses (IOL) have been manufactured and can be divided into three types according to the location of correction component; front-toric IOL (correction on anterior IOL surface), back-toric IOL (correction on posterior IOL surface), and bi-toric IOL (correction on ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01439-4
更新日期：2020-04-28 00:00:00
abstract：BACKGROUND:To report a rare case of bilateral Purtscher-like retinopathy in a Chinese female patient with dermatomyositis. CASE PRESENTATION:An 18-year-old woman with lower extremity muscle weakness was admitted due to decreased vision of both eyes for two weeks. Ophthalmic examination revealed violaceous eruption on ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-13-36
更新日期：2013-07-24 00:00:00
