Abstract:
BACKGROUND:To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS:A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS:Twenty-one patients (33 eyes) were diagnosed as syphilitic uveitis. Posterior segment involvement was found in 32 eyes (97.0%). Vitreous haze, neuroretinitis, and posterior placoid chorioretinitis were mainly found in patients with a relatively short duration of the disease, while diffuse chorioretinitis, pseudoretinitis pigmentosa, cystoid macular edema, and epiretinal membrane were found in patients with relatively long duration of ocular involvement. A low best-corrected visual acuity (P = 0.022) and a delay of syphilis treatment (P < 0.001) were associated with a significantly worse visual outcome. CONCLUSIONS:Syphilitic uveitis should be included in the differential diagnosis of any form of posterior ocular inflammation. The pattern of ocular involvement may change with the disease progression.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Zhang X,Du Q,Ma F,Lu Y,Wang M,Li Xdoi
10.1186/s12886-017-0491-6subject
Has Abstractpub_date
2017-06-19 00:00:00pages
95issue
1issn
1471-2415pii
10.1186/s12886-017-0491-6journal_volume
17pub_type
杂志文章abstract:BACKGROUND:To examine the clinical features of acute acquired comitant esotropia (AACE) and to evaluate the clinical effectiveness of a single injection of botulinum toxin type A (BTXA) on binocular visual function (BVF). METHODS:This retrospective, observational case series study enrolled patients with AACE examined ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01739-9
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:Differences in the increase in matrix metalloproteinase (MMP) and decrease in tissue inhibitor of metalloproteinase (TIMP) activity may contribute to the different characteristics observed clinically on decreased intraocular pressure in patients with glaucoma or ocular hypertension. The purpose of this study...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0202-8
更新日期:2016-03-08 00:00:00
abstract:BACKGROUND:The purpose of this study was to identify the genetic cause and describe the clinical phenotype of Schnyder corneal dystrophy (SCD) in six unrelated probands. METHODS:We identified two white Czech, two white British and two South Asian families with a clinical diagnosis of SCD. Ophthalmic assessment include...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0918-8
更新日期:2018-09-17 00:00:00
abstract:BACKGROUND:Immune responses play a key role in the pathogenesis and progression of polypoidal choroidal vasculopath (PCV) and age-related macular degeneration (AMD). In this study, we determined the Th cell-associated immune responses by measuring the cytokine expression of peripheral blood mononuclear cells (PBMC) in ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0251-z
更新日期:2016-06-07 00:00:00
abstract:BACKGROUND:To investigate the accommodative loads change needed to maintain binocular fusion in patients with intermittent exotropia (IXT). METHODS:Seventeen consecutive patients with basic IXT and 15 normal controls were recruited. The WAM-5500 autorefractor (GrandSeiko, Fukuyama, Japan) was used to measure refractiv...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0260-y
更新日期:2016-06-07 00:00:00
abstract:BACKGROUND:Central corneal thickness (CCT) measurement has become an important test in the diagnosis and management of glaucoma. Currently, ultrasound corneal thickness measurement (pachymetry) is the most frequently used clinical technique and the gold standard to assess CCT. Newer instruments are currently available ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0116-x
更新日期:2015-09-29 00:00:00
abstract:BACKGROUND:This study aimed to investigate patient adherence to face-down positioning (FDP) and non-supine positioning (NSP) following vitrectomy with gas tamponade for treating macular holes (MHs). METHODS:Nursing records of 92 patients who underwent vitrectomy with gas tamponade for small-diameter (diameter < 400 μm...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0979-8
更新日期:2018-12-14 00:00:00
abstract:BACKGROUND:To evaluate the differences between the predicted and achieved lenticule thickness (ΔLT) after small incision lenticule extraction (SMILE) surgery and investigate relationships between ΔLT and predicted lenticule thickness in SMILE. METHODS:A total of 184 eyes from 184 consecutive patients who underwent SMI...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01374-4
更新日期:2020-03-17 00:00:00
abstract:BACKGROUND:Acute acquired comitant esotropia (AACE) is a type of strabismus characterized by a sudden onset of large angle esotropia with diplopia, which often occurs in children after infancy, teenagers, and young adolescents. However, studies on the surgical outcomes of only adults are rare. The purpose of this artic...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01793-3
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening hematological condition associated with deficiency in ADAMTS13. Ocular manifestations associated with TTP are uncommon. CASE PRESENTATION:Here we report a case where a 44 year old female patient with a history of symptomatic anemia and cotton w...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01719-z
更新日期:2020-11-19 00:00:00
abstract:BACKGROUND:Retinopathy of Prematurity (ROP) is one of the most common causes of childhood blindness worldwide. Comparisons of anti-VEGF and laser treatments in ROP are relatively lacking, and the data are scattered and limited. The objective of this meta-analysis is to compare the efficacy of both treatments in type-1 ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12886-018-0685-6
更新日期:2018-01-30 00:00:00
abstract:BACKGROUND:Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist called cryosim-3 (C3, 1-diisopropylphosphorylnonane) which selectively activates TRPM8 (linked to co...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12886-017-0495-2
更新日期:2017-06-26 00:00:00
abstract:BACKGROUND:To assess the precision and agreement of measurements of higher order aberrations (HOAs) obtained with a ray tracing aberrometer (iTrace) and a Hartmann-Shack aberrometer (Topcon KR-1 W). METHODS:Prospective evaluation of the diagnostic test. Data from the right eyes of 92 normal subjects obtained using the...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0683-8
更新日期:2018-01-27 00:00:00
abstract:BACKGROUND:Patients with primary angle closure/glaucoma (PAC/PACG) with extensive peripheral anterior synechiae (PAS), and coexisting cataract, increasingly have been treated with phacoemulsification combined with goniosynechialysis (Phaco-GSL). Since the mechanisms of acute and chronic PAC/PACG may differ, the treatme...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1070-9
更新日期:2019-03-04 00:00:00
abstract:BACKGROUND:Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0883-2
更新日期:2018-09-03 00:00:00
abstract:BACKGROUND:To screen for visual impairment in Malaysian preschool children. METHODS:Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs ste...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-16
更新日期:2013-04-19 00:00:00
abstract:BACKGROUND:Although the association between metabolic syndrome and intraocular pressure is well known, the relationship between the intraocular pressure and different combination of the components of metabolic syndrome has not been actively researched yet. The study aimed to investigate the relationship between the int...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0263-8
更新日期:2016-06-06 00:00:00
abstract:BACKGROUND:To evaluate the efficacy of triple therapy consisting of single-session photodynamic therapy (PDT), intravitreal bevacizumab (IVB) and intravitreal triamcinolone (IVT) as initial pulse therapy followed by repeat intravitreal bevacizumab injections for maintenance treatment in neovascular age-related macular ...
journal_title:BMC ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2415-7-10
更新日期:2007-06-07 00:00:00
abstract:BACKGROUND:To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world settings. METHODS:In this retrospective, observational, multicentre study in Slovenia, medical reco...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12886-018-1005-x
更新日期:2018-12-20 00:00:00
abstract:BACKGROUND:Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular pressure (IOP)-lowering medication change rates in patients newly treated with latanoprost or travoprost-...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2415-11-13
更新日期:2011-06-13 00:00:00
abstract:BACKGROUND:The aim of this study was to compare superior and temporal clear corneal incisions of uneventful phacoemulsification and in-the-bag intraocular lens implantation on intraocular pressure control and the bleb morphology in eyes that have undergone previous successful trabeculectomy. METHODS:In this Prospectiv...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12886-017-0500-9
更新日期:2017-06-26 00:00:00
abstract:BACKGROUND:Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes. Our present study was to measure the cone IZ area by optical coherence tomography (OCT),...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0862-7
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:The presence of an intraocular cilium is very rare and the response of the eye to the cilium is variable. We present the case of a patient with a cilium found in the vitreous cavity during vitrectomy for rhegmatogenous retinal detachment 40 years following penetrating eye injury. To our knowledge, this is th...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0010-6
更新日期:2015-03-12 00:00:00
abstract:BACKGROUND:Glial heterotopias are rare, benign, congenital, midline, non-teratomatous extracranial glial tissue. They may masquerade as encephalocoele or dermoid cyst and mostly present in nose. Herein, we present an unusual case of glial heterotopia of the orbit with unilateral blindness. CASE PRESENTATION:A 6 year-o...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-34
更新日期:2011-11-16 00:00:00
abstract:BACKGROUND:To investigate the corneal biomechanical changes in primary open angle glaucoma (POAG) patients treated with long-term prostaglandin analogue (PGA). METHODS:One hundred eleven newly diagnosed POAG patients, including 43 high tension glaucoma (HTG) and 68 normal tension glaucoma (NTG), were measured by Corvi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01693-6
更新日期:2020-10-20 00:00:00
abstract:BACKGROUND:To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma. CASE PRESENTATION:We present a case of a 94-year-old male with choroidal melanoma of the right eye imaged with MRI and ocular ultrasound to aid in the detection of extrascleral exte...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0990-0
更新日期:2018-12-12 00:00:00
abstract:BACKGROUND:Cavernous carotid aneurysm (CCA) represents 2-9% of all intracranial aneurysms and 15% of internal carotid artery (ICA) aneurysms; additionally, giant aneurysms are those aneurysms that are > 25 mm in size. Bilateral CCAs account for 11-29% of patients and are commonly associated with structural weaknesses i...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0687-4
更新日期:2018-02-02 00:00:00
abstract:BACKGROUND:To understand which irregular corneal parameters determine the visual quality in keratoconus subjects. METHODS:The cross-sectional study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Amsler-Krumeich classification. We obtained measurements in two ways: (a) by project...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01737-x
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:Adenovirus (Ad), associated with significant morbidity, has no topical treatment. A leading CTC compound (CTC-96), a Co(III) chelate, was found to have potent in vitro and in vivo antiviral efficacy against herpes viruses. In this study CTC-96 is being tested for possible anti-Adenovirus activity. METHODS:T...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-22
更新日期:2006-06-05 00:00:00
abstract:BACKGROUND:To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. METHODS:This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. I...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0719-0
更新日期:2018-02-20 00:00:00