Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases.

abstract：BACKGROUND:The aim of this study was to investigate the changes in corneal epithelial thickness along the principle meridians of astigmatic corneas after six months of overnight spherical myopic orthokeratology (OK) lens wear. METHODS:This is a prospective study. Fifty-seven subjects with up to 1.50 diopters (D) of co...

journal_title：BMC ophthalmology

authors： Zhou J,Xue F,Zhou X,Naidu RK,Qian Y

更新日期：2020-06-19 00:00:00

abstract：BACKGROUND:Tibetan Plateau is a highland area with special geographical location, time zone, and ethnic composition. We herein report the rationale, methodology and baseline data of the school-based childhood cohort study named Lhasa Childhood Eye Study (LCES), with the primary objective to pursue a comprehensive under...

journal_title：BMC ophthalmology

authors： Chen W,Fu J,Meng Z,Li L,Su H,Dai W,Yao Y

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:While pars plana vitrectomy (PPV) has become the third most commonly performed surgery in the world, it can also induce multiple post complications easily. Among them, cataract progression is the most frequent one that can lead to blindness eventually. METHODS:To understand the underlying mechanisms of post...

journal_title：BMC ophthalmology

authors： Ji Y,Rong X,Lu Y

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:The use of capsular tension ring (CTR) implantation to treat cataract patients with weak zonules is still controversial. The aim of this study was to examine the effects of CTR implantation on capsular stability after phacoemulsification in patients with weak zonules, especially patients who have undergone p...

journal_title：BMC ophthalmology

authors： Yang S,Jiang H,Nie K,Feng L,Fan W

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes. Our present study was to measure the cone IZ area by optical coherence tomography (OCT),...

journal_title：BMC ophthalmology

authors： Gu R,Deng G,Jiang Y,Jiang C,Xu G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:This paper presents and tests a comprehensive computerised system of analysis of digital images of posterior capsule opacification (PCO). It updates and expands significantly on a previous presentation to include facilities for selecting user defined central areas and for registering and subsequent merging o...

journal_title：BMC ophthalmology

authors： Aslam TM,Patton N,Rose CJ

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation. CASE PRESENTATION:A 56-year-old male patient presented at our outpatient clinic after becoming aware of dec...

journal_title：BMC ophthalmology

authors： Kohmoto R,Kobayashi T,Sato T,Kimura D,Fukumoto M,Tajiri K,Kida T,Ikeda T

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:The Heimann-Bielschowsky phenomenon (HBP) is an underrecognized condition characterized by slow, pendular, vertical oscillations of the eye accompanying monocular vision loss. Hypotropic dissociated vertical deviation (DVD) is another rare condition induced by asymmetric visual input. This report documents a...

journal_title：BMC ophthalmology

authors： Choi HJ,Chun BY

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Raised intraocular pressure (IOP) is the only causal risk factor for glaucoma that can be therapeutically manipulated to change the course of the disease process. Though Goldman applanation tonometry (GAT) is the "gold standard" for IOP measurement, readings of IOP with GAT are affected by central corneal th...

journal_title：BMC ophthalmology

authors： Gelaw Y

更新日期：2012-11-27 00:00:00

abstract：BACKGROUND:To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world settings. METHODS:In this retrospective, observational, multicentre study in Slovenia, medical reco...

journal_title：BMC ophthalmology

authors： Jaki Mekjavić P,Gregorčič B,Oberč C,Podgoršek S

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:There is a huge need for the availability of transplantable donor corneas worldwide to reduce the burden of corneal blindness due to corneal opacity. Voluntary eye donation depends on the awareness levels of various stakeholders in the community. This study aimed to assess the awareness level regarding eye d...

journal_title：BMC ophthalmology

authors： Ronanki VR,Sheeladevi S,Ramachandran BP,Jalbert I

更新日期：2014-03-06 00:00:00

abstract：BACKGROUND:To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitre...

journal_title：BMC ophthalmology

authors： Liu J,Chen Y,Wang S,Zhang X,Zhao P

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:To study the influencing factors for different healing patterns of patients with idiopathic macular holes (IMH) after vitrectomy surgery performed with the internal limiting membrane (ILM) flap technique. METHODS:This study was a retrospective, consecutive, observational case series study. We recruited 52 I...

journal_title：BMC ophthalmology

authors： Liu Y,Wu C,Wang Y,Dong Y,Liang D,Xiao B,Han Q,Chu Y

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Ocular signs of Fabry disease can be seen in the first decade of life. METHODS:We examined the occurrence of ocular signs in 232 paediatric patients in the Fabry Outcome Survey (FOS) international registry and looked for relationships between the presence of eye findings and disease severity as measured by ...

journal_title：BMC ophthalmology

authors： Kalkum G,Pitz S,Karabul N,Beck M,Pintos-Morell G,Parini R,Rohrbach M,Bizjajeva S,Ramaswami U

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. METHODS:The present study was a retros...

journal_title：BMC ophthalmology

authors： Karabela Y,Eliacik M,Kaya F

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:A patient's health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark. METHODS:This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determ...

journal_title：BMC ophthalmology

authors： Jandorf S,Krogh Nielsen M,Sørensen K,Sørensen TL

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening conditions that initially affect the skin and mucous membranes. The aim of this study was to compare the acute ocular manifestations between SJS and TEN. METHODS:The initial presenting ophthalmic records of pat...

journal_title：BMC ophthalmology

authors： Chow LLW,Shih KC,Chan JCY,Lai JSM,Ng ALK

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:To evaluate the long-term outcomes of Argon laser photocoagulation compared to surgical direct cyclopexy in small-size cyclodialysis cleft patients. METHODS:This is a retrospective study. Small-size cyclodialysis cleft patients who underwent Argon laser photocoagulation and surgical direct cyclopexy were re...

journal_title：BMC ophthalmology

authors： Han JC,Kwun YK,Cho SH,Kee C

更新日期：2015-09-24 00:00:00

abstract：:Meibomian gland dysfunction (MGD) is the major cause of evaporative dry eye disease (EDED) and dysfunction is widely thought to mechanistically involve ductal hyperkeratinization, plugging and obstruction. This review re-evaluates the role of hyperkeratinization in MGD based on more recent findings from mouse models. ...

journal_title：BMC ophthalmology

authors： Jester JV,Parfitt GJ,Brown DJ

更新日期：2015-12-17 00:00:00

abstract：BACKGROUND:Nonarteritic ischemic optic neuropathy affects the anterior portion of the optic nerve and is characterized by sudden, painless visual loss. The affected eye has a relative afferent pupillary defect. The typical funduscopic appearance includes optic disc edema, with associated nerve fiber layer hemorrhage. R...

journal_title：BMC ophthalmology

authors： Sadaba LM,Garcia-Layana A,Maldonado MJ,Berian JM

更新日期：2006-10-11 00:00:00

abstract：BACKGROUND:To evaluate the 6-month clinical outcomes of Flexivue Microlens refractive corneal inlay in emmetropic patients in Asia for the surgical compensation of presbyopia. METHODS:In this retrospective study, corneal inlay implantation was done using a femtosecond laser. The follow-up period was 6 months. Near/int...

journal_title：BMC ophthalmology

authors： Han G,Lim DH,Yang CM,Park GH,Park DY,Moon HS,Lee JM,Lee JH,Chung TY

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:A few case reports have described accidental eye injuries caused by fish hooks. The severity of ocular injuries is dependent on the involved ocular structures. Severe ocular injuries due to fish hooks are rare. We describe open globe and penetrating eyelid injuries from fish hooks at the Baltic Sea. METHODS...

journal_title：BMC ophthalmology

authors： Purtskhvanidze K,Saeger M,Treumer F,Nölle B,Roider J

更新日期：2019-01-21 00:00:00

abstract：BACKGROUND:Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in ...

journal_title：BMC ophthalmology

authors： Tokimitsu M,Murata M,Toriyama Y,Hirano T,Iesato Y,Murata T

更新日期：2016-07-19 00:00:00

abstract：BACKGROUND:The mechanism by which vitrectomy improves macular edema in patients with branch retinal vein occlusion remains unclear, although intraocular levels of vascular endothelial growth factor have been suggested to influence the visual prognosis and macular edema. METHODS:A series of 54 consecutive patients (54 ...

journal_title：BMC ophthalmology

authors： Noma H,Funatsu H,Mimura T,Eguchi S,Shimada K

更新日期：2010-04-29 00:00:00

abstract：BACKGROUND:Blank cartridge guns are generally regarded as being harmless and relative safe. However recent published articles demonstrated that the gas pressure from the exploding propellant of blank cartridge is powerful enough to penetrate the thoracic wall, abdominal muscle, small intestine and the skull. And there ...

journal_title：BMC ophthalmology

authors： Moon S,Lim SH

更新日期：2014-03-03 00:00:00

abstract：BACKGROUND:To report a rare case of bilateral Purtscher-like retinopathy in a Chinese female patient with dermatomyositis. CASE PRESENTATION:An 18-year-old woman with lower extremity muscle weakness was admitted due to decreased vision of both eyes for two weeks. Ophthalmic examination revealed violaceous eruption on ...

journal_title：BMC ophthalmology

authors： Yan Y,Shen X

更新日期：2013-07-24 00:00:00

abstract：PURPOSE:More than 3 million cataract extractions are undertaken in India annually. Almost 60% of these operations are intracapsular Cataract Extractions. The subsequent optical correction is provided by aphakic spectacles. The aim of this study is to assess visual outcome and perceived benefits of post-operative use of...

journal_title：BMC ophthalmology

authors： Gupta SK,Murthy GV,Sharma N

更新日期：2003-07-28 00:00:00

abstract：BACKGROUND:To develop a side-view imaging technique for observing the dynamic behavior of posterior chamber structures (PCSs) in porcine eyes which mimics closed-eye cataract surgery in humans. METHODS:Enucleated porcine eyes were placed into liquid nitrogen for 5 seconds and immediately bisected at about a 45-degree ...

journal_title：BMC ophthalmology

authors： Tasaka Y,Minami N,Suzuki T,Kawasaki S,Zheng X,Shiraishi A,Uno T,Miyake K,Ohashi Y

更新日期：2013-09-23 00:00:00

abstract：:Ophthalmologists and researchers in ophthalmology understand what a rapidly evolving field ophthalmology is, and that to conduct good research it is essential to use the latest and best methods. In outcomes research, one modern initiative has been to conduct holistic measurement of outcomes inclusive of the patient's ...

journal_title：BMC ophthalmology

authors： Pesudovs K

更新日期：2006-06-15 00:00:00

abstract：BACKGROUND:The aim of the study is to investigate risk factors for future falls in subject with primary open angle glaucoma (POAG). METHODS:All participants answered the following question at their baseline ophthalmic examination: Have you had any falls in the last year? (Yes/No). All study participants answered the s...

journal_title：BMC ophthalmology

authors： Adachi S,Yuki K,Awano-Tanabe S,Ono T,Murata H,Asaoka R,Tsubota K

更新日期：2017-11-25 00:00:00