Abstract:
BACKGROUND:Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in a chronic case of unexplained scotoma that developed after femoral fracture. The patient exhibited normal fluorescein angiography (FA) findings and a normal retinal appearance. CASE PRESENTATION:A 42-year-old Japanese man with a history of bilateral, unexplained paracentral scotoma that developed after femoral fracture and pulmonary fat embolism due to a car accident 20 years ago was referred to our outpatient clinic. Initial ophthalmological examination revealed unremarkable retinal findings. Goldmann perimetry, FA, and full field electroretinography showed no pathological changes. Although fat embolism in the retinal vasculature was suspected, psychosomatic visual field defects could not be ruled out. We performed OCTA, which clearly delineated capillary dropout in the deep retinal capillary plexus. A final diagnosis of paracentral acute middle maculopathy secondary to Purtscher's retinopathy was made on the basis of this finding. CONCLUSIONS:Our findings suggest that OCTA clearly and noninvasively delineates the deep retinal capillary plexus and the superficial capillary plexus. Because conventional FA provides limited depth resolution, capillary dropout restricted within the deep capillary plexus cannot be detected, particularly when the superficial capillary plexus is well preserved. Thus, OCTA can be a useful tool for the detection of capillary dropout in the deep retinal capillary plexus.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Tokimitsu M,Murata M,Toriyama Y,Hirano T,Iesato Y,Murata Tdoi
10.1186/s12886-016-0298-xsubject
Has Abstractpub_date
2016-07-19 00:00:00pages
113issn
1471-2415pii
10.1186/s12886-016-0298-xjournal_volume
16pub_type
杂志文章abstract:BACKGROUND:To determine the rate of glaucoma following congenital cataract surgery at Moorfields Eye Hospital (MEH), and to investigate potential risk factors for glaucoma in our case series. METHODS:A retrospective case notes review was undertaken of all congenital cataract lensectomies performed at MEH between 1994 ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-7-13
更新日期:2007-09-11 00:00:00
abstract:BACKGROUND:To explore the molecular genetic cause of a four-generation autosomal dominant congenital cataract family in China. METHODS:Targeted region sequencing was performed to screen for the potential mutation, and Sanger sequencing was used to confirm the mutation. The homology model was constructed to identify th...
journal_title:BMC ophthalmology
pub_type: 杂志文章
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更新日期:2020-11-20 00:00:00
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更新日期:2019-02-26 00:00:00
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更新日期:2017-12-19 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
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更新日期:2011-11-15 00:00:00
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更新日期:2020-06-16 00:00:00
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更新日期:2011-08-04 00:00:00
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更新日期:2015-01-24 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12886-016-0243-z
更新日期:2016-08-16 00:00:00
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doi:10.1186/s12886-018-0968-y
更新日期:2018-12-07 00:00:00
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doi:10.1186/s12886-019-1262-3
更新日期:2019-12-12 00:00:00
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pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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更新日期:2020-08-28 00:00:00
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doi:10.1186/1471-2415-3-9
更新日期:2003-07-28 00:00:00
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pub_type: 杂志文章
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更新日期:2018-12-18 00:00:00
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doi:10.1186/1471-2415-14-11
更新日期:2014-01-30 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2016-08-03 00:00:00
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更新日期:2019-05-24 00:00:00
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pub_type: 杂志文章
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更新日期:2015-09-29 00:00:00
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pub_type: 杂志文章
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更新日期:2020-11-26 00:00:00
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更新日期:2018-06-27 00:00:00
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更新日期:2016-03-08 00:00:00
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更新日期:2016-11-08 00:00:00