Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.

abstract：BACKGROUND:Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implants and anti-vascular endothelial growth factor (VEGF). The goal of this study is to compare the effec...

journal_title：BMC ophthalmology

authors： Gao L,Zhou L,Tian C,Li N,Shao W,Peng X,Shi Q

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:To investigate the 3-month postoperative performance and safety after implantation of a trifocal intraocular lens (IOL) in a Korean population. METHODS:This was a clinical, prospective, multicenter, single-arm study. Forty-four subjects (88 eyes) with bilateral cataract with expected postoperative corneal a...

journal_title：BMC ophthalmology

authors： Kim TI,Chung TY,Kim MJ,Lee K,Hyon JY

更新日期：2020-07-15 00:00:00

abstract：BACKGROUND:Fungal keratitis is difficult to treat that can result in corneal blindness requiring penetrating keratoplasty and in fungal endothalmitis. We report a case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton. CASE PRESENTATION:A 77-year old male presented with ocular pain, conjunc...

journal_title：BMC ophthalmology

authors： Jin KW,Jeon HS,Hyon JY,Wee WR,Suh W,Shin YJ

更新日期：2014-07-11 00:00:00

abstract：BACKGROUND:The performance of glaucoma diagnostic systems could be conceivably improved by the integration of functional and structural test measurements that provide relevant and complementary information for reaching a diagnosis. The purpose of this study was to investigate the performance of data fusion methods and ...

journal_title：BMC ophthalmology

authors： Bizios D,Heijl A,Bengtsson B

更新日期：2011-08-04 00:00:00

abstract：BACKGROUND:A patient's health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark. METHODS:This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determ...

journal_title：BMC ophthalmology

authors： Jandorf S,Krogh Nielsen M,Sørensen K,Sørensen TL

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation. CASE PRESENTATION:A 56-year-old male patient presented at our outpatient clinic after becoming aware of dec...

journal_title：BMC ophthalmology

authors： Kohmoto R,Kobayashi T,Sato T,Kimura D,Fukumoto M,Tajiri K,Kida T,Ikeda T

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Retinal dystrophies display a considerably wide range of phenotypic variability, which can make diagnosis and clinical staging difficult. The aim of the study is to analyze the contribution of retro-mode imaging (RMI) and fundus autofluorescence (FAF) to the characterization of retinal dystrophies. METHODS:...

journal_title：BMC ophthalmology

authors： Maurizio BP,Pierluigi I,Stelios K,Stefano V,Marialucia C,Ilaria Z,Francesco B

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:To study the healing processes of partial thickness wounds in the adult rabbit cornea after grafting a porous collagen-glycosaminoglycan copolymer matrix (CG). METHODS:In this study, the regeneration of surgically-induced rabbit corneal defect implanted with CG was investigated. The corneal partial thicknes...

journal_title：BMC ophthalmology

authors： Wu SY,Pan CY,Shen EP,Tzeng IS,Hsu WC

更新日期：2018-10-25 00:00:00

abstract：PURPOSE:More than 3 million cataract extractions are undertaken in India annually. Almost 60% of these operations are intracapsular Cataract Extractions. The subsequent optical correction is provided by aphakic spectacles. The aim of this study is to assess visual outcome and perceived benefits of post-operative use of...

journal_title：BMC ophthalmology

authors： Gupta SK,Murthy GV,Sharma N

更新日期：2003-07-28 00:00:00

abstract：BACKGROUND:Adenovirus (Ad), associated with significant morbidity, has no topical treatment. A leading CTC compound (CTC-96), a Co(III) chelate, was found to have potent in vitro and in vivo antiviral efficacy against herpes viruses. In this study CTC-96 is being tested for possible anti-Adenovirus activity. METHODS:T...

journal_title：BMC ophthalmology

authors： Epstein SP,Pashinsky YY,Gershon D,Winicov I,Srivilasa C,Kristic KJ,Asbell PA

更新日期：2006-06-05 00:00:00

abstract：BACKGROUND:We present a case of post-traumatic endophthalmitis with relatively good prognosis caused by Gordonia sputi, which, to our knowledge is the first case in the literature. CASE PRESENTATION:A 24 year old man, who underwent an intraocular foreign body extraction half a month before presentation in the left eye...

journal_title：BMC ophthalmology

authors： Fang W,Li J,Cui HS,Jin X,Zhai J,Dai Y,Li Y

更新日期：2017-10-11 00:00:00

abstract：:Conjunctival and subconjunctival fibrogenesis and inflammation are sight compromising side effects that can occur subsequent to glaucoma filtration surgery. Despite initial declines in intraocular pressure resulting from increasing aqueous outflow, one of the activated responses includes marshalling of proinflammatory...

journal_title：BMC ophthalmology

authors： Yamanaka O,Kitano-Izutani A,Tomoyose K,Reinach PS

更新日期：2015-12-17 00:00:00

abstract：BACKGROUND:To assess the reliability of the measurements obtained with the PalmScan, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods. METHODS:Transversal, descriptive, and comparative study. We recorded the axial length (AL), anterior...

journal_title：BMC ophthalmology

authors： Velez-Montoya R,Shusterman EM,López-Miranda MJ,Mayorquin-Ruiz M,Salcedo-Villanueva G,Quiroz-Mercado H,Morales-Cantón V

更新日期：2010-03-24 00:00:00

abstract：BACKGROUND:Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in ...

journal_title：BMC ophthalmology

authors： Tokimitsu M,Murata M,Toriyama Y,Hirano T,Iesato Y,Murata T

更新日期：2016-07-19 00:00:00

abstract：BACKGROUND:To screen for visual impairment in Malaysian preschool children. METHODS:Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs ste...

journal_title：BMC ophthalmology

authors： Premsenthil M,Manju R,Thanaraj A,Rahman SA,Kah TA

更新日期：2013-04-19 00:00:00

abstract：BACKGROUND:Graves' disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves' Ophthalmopathy. Not all patients respond well to the standard therapy of systemic glucocorticoid admini...

journal_title：BMC ophthalmology

authors： Rau A,Klopfer M,Rommel N,Rau-Fornefeld M,Kolk A

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:Older drivers aged ≥70 years old have among the highest rates of motor vehicle collisions (MVC) compared to other age groups. Driving is a highly visual task, and older adults have a high prevalence of vision impairment compared to other ages. Most studies addressing visual risk factors for MVCs by older dri...

journal_title：BMC ophthalmology

authors： Owsley C,McGwin G Jr,Antin JF,Wood JM,Elgin J

更新日期：2018-02-07 00:00:00

abstract：BACKGROUND:To explore the molecular genetic cause of a four-generation autosomal dominant congenital cataract family in China. METHODS:Targeted region sequencing was performed to screen for the potential mutation, and Sanger sequencing was used to confirm the mutation. The homology model was constructed to identify th...

journal_title：BMC ophthalmology

authors： Li D,Xu C,Huang D,Guo R,Ji J,Liu W

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Retinal artery occlusion caused by myxoma is relatively rare. There are several points that should be taken into consideration to avoid overlooking this disorder. CASE PRESENTATION:This case report describes a 43-year-old woman with sudden vision loss in her left eye for 20 days after single sudden syncope....

journal_title：BMC ophthalmology

authors： Yu Y,Zhu Y,Dong A,Su Z

更新日期：2014-12-23 00:00:00

abstract：BACKGROUND:To gain more insight into genetic causes of cerebral visual impairment (CVI) in children and to compare ophthalmological findings between genetic and acquired forms of CVI. METHODS:The clinical data of 309 individuals (mainly children) with CVI, and a visual acuity ≤ 0.3 were analyzed for etiology and ocula...

journal_title：BMC ophthalmology

authors： Bosch DG,Boonstra FN,Willemsen MA,Cremers FP,de Vries BB

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:To report six cases of CD34+ fibroblastic mesenchymal tumours, which are uncommon neoplasms in the orbit. CASE PRESENTATION:Six patients presenting with proptosis and palpable mass who were later diagnosed with fibrous solitary tumours, fibrous histocytoma or haemangiopericytoma in the orbit were included. ...

journal_title：BMC ophthalmology

authors： Jung SK,Paik JS,Park GS,Yang SW

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery. METHODS:Nonrandomized clinical trial. Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to Septe...

journal_title：BMC ophthalmology

authors： Li S,Hu Y,Guo R,Shao Y,Zhao J,Zhang J,Wang J

更新日期：2019-02-21 00:00:00

abstract：BACKGROUND:Retinopathy of Prematurity (ROP) is one of the most common causes of childhood blindness worldwide. Comparisons of anti-VEGF and laser treatments in ROP are relatively lacking, and the data are scattered and limited. The objective of this meta-analysis is to compare the efficacy of both treatments in type-1 ...

journal_title：BMC ophthalmology

authors： Li Z,Zhang Y,Liao Y,Zeng R,Zeng P,Lan Y

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND:Uncorrected refractive errors contribute enormously to the burden of avoidable visual impairment worldwide. There is a huge disparity in different parts of the globe in context to spectacle coverage for distance vision. This study was undertaken with objectives of determining prevalence of spectacle coverage...

journal_title：BMC ophthalmology

authors： Malhotra S,Kalaivani M,Rath R,Prasad M,Vashist P,Gupta N,Senjam SS,Gupta SK

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular pressure (IOP)-lowering medication change rates in patients newly treated with latanoprost or travoprost-...

journal_title：BMC ophthalmology

authors： Fain JM,Kotak S,Mardekian J,Bacharach J,Edward DP,Rauchman S,Brevetti T,Fox JL,Lovelace C

更新日期：2011-06-13 00:00:00

abstract：BACKGROUND:To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION:A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and...

journal_title：BMC ophthalmology

authors： Ong SJ,Jung SM,Lin HC

更新日期：2017-07-27 00:00:00

abstract：BACKGROUND:The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. METHODS:The present study was a retros...

journal_title：BMC ophthalmology

authors： Karabela Y,Eliacik M,Kaya F

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model. METHODS:Pharmacokinetic analyses determined the corticosteroid con...

journal_title：BMC ophthalmology

authors： Araki-Sasaki K,Katsuta O,Mano H,Nagano T,Nakamura M

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:The Heimann-Bielschowsky phenomenon (HBP) is an underrecognized condition characterized by slow, pendular, vertical oscillations of the eye accompanying monocular vision loss. Hypotropic dissociated vertical deviation (DVD) is another rare condition induced by asymmetric visual input. This report documents a...

journal_title：BMC ophthalmology

authors： Choi HJ,Chun BY

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:This objective of the review and analysis is to demonstrate that acyclovir (ACV) 3% ophthalmic ointment is superior to idoxuridine (IDU) in treating herpetic keratitis (HK) presenting as dendritic and geographic ulcer sub-types. METHODS: DATA SOURCES:Publications in human subjects were identified by search...

journal_title：BMC ophthalmology

authors： Balderson DE,Cai G,Fries MA,Kleinman DM,McLaughlin MM,Trivedi TM,Wurzelmann JI,Young SB

更新日期：2015-04-17 00:00:00