Abstract：
BACKGROUND:We report a case of Meige's syndrome induced by an atypical antipsychotic (blonanserin) that presented with refractory dry eye disease. CASE PRESENTATION:A 37-year-old woman with a 6-month history of foreign body sensation in the eyes and difficulty in opening her eyes was treated at a local clinic for dry eye disease. Despite this treatment, her symptoms did not improve and she was transferred to our attention. Our assessment revealed involuntary movements of her eyelids accompanied by repetitive pursing of her lips. She had been undergoing treatment with blonanserin for 5 years for schizophrenia. She was diagnosed with drug-induced Meige's syndrome after a psychiatric and neurological consultation. After a 2-month gradual dose reduction and discontinuing blonanserin, involuntary movements of the eyelids with oromandibular dystonia were resolved. Three months after discontinuing blonanserin, there was no recurrence of symptoms, and she had no exacerbation of psychotic symptoms. CONCLUSIONS:In patients with refractory dry eye disease, especially those with involuntary movements of the eyelids with oromandibular dystonia, it is important to ask about their psychotropic medications and to consider the possibility of drug-induced Meige's syndrome and discontinuation of medications, if possible.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Kim JE,Jung JWdoi
10.1186/s12886-020-01738-wsubject
Has Abstractpub_date
2020-12-02 00:00:00pages
474issue
1issn
1471-2415pii
10.1186/s12886-020-01738-wjournal_volume
20pub_type
杂志文章abstract：BACKGROUND:To report a rare case of bilateral Purtscher-like retinopathy in a Chinese female patient with dermatomyositis. CASE PRESENTATION:An 18-year-old woman with lower extremity muscle weakness was admitted due to decreased vision of both eyes for two weeks. Ophthalmic examination revealed violaceous eruption on ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2018-11-03 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
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更新日期：2012-11-27 00:00:00
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pub_type： 社论,评审
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pub_type： 杂志文章
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更新日期：2015-09-29 00:00:00
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