Abstract：
BACKGROUND:Goldenhar Syndrome is characterized by malformations of multiple anatomical districts. Between these, bulbar dermoids are common and represent a significant clinical problem as they can affect both ocular function and aesthetic comfort.Histologic characterization of dermoids has been extensively performed; however, no reports exist describing in vivo confocal microscopy (IVCM) of these lesions. We aimed to (i) describe the in vivo confocal morphology of limbal dermoids in Goldenhar syndrome and (ii) compare these findings with standard light microscopy. CASE PRESENTATION:A 15-year-old Caucasian female affected by Goldenhar Syndrome showed a left, infero-temporal, limbal neoformation, with extension to the left orbital region. Prior to surgical removal, IVCM was performed with the Heidelberg Retina Tomograph II, Cornea Module, using the "section" modality. The IVCM sections showed structures resembling corneal epithelium and vascular structures. Surgical removal of the lesion was decided as it caused poor eyelid closure. After surgical removal, sectioning and standard optical microscopy were performed. The comparison between IVCM imaging and standard microscopy sections were highly correlated in the detection of the pilar and vascular structures. CONCLUSIONS:This study showed that IVCM may be a useful technique to study limbal dermoids, given its ability to detect typical microscopic features and its comparability to optical microscopy, which is the current standard.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Triolo G,Ferrari G,Doglioni C,Rama Pdoi
10.1186/1471-2415-13-55subject
Has Abstractpub_date
2013-10-16 00:00:00pages
55issn
1471-2415pii
1471-2415-13-55journal_volume
13pub_type
杂志文章abstract：BACKGROUND:Ocular coloboma is an excavation of ocular structures that occurs due to abnormal fusion of the embryonic optic fissure. Further, cleft lip/palate (CL/P), a congenital midline abnormality, is caused by a defect in the fusion of the frontonasal, maxillary, and mandibular prominences. No study has reported the...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01696-3
更新日期：2020-10-19 00:00:00
abstract：BACKGROUND:Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS:Six focus group sessions were conducted at t...
journal_title：BMC ophthalmology
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更新日期：2018-01-16 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the changes in corneal epithelial thickness along the principle meridians of astigmatic corneas after six months of overnight spherical myopic orthokeratology (OK) lens wear. METHODS:This is a prospective study. Fifty-seven subjects with up to 1.50 diopters (D) of co...
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doi：10.1186/s12886-020-01477-y
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abstract：BACKGROUND:The aim of this study was to compare superior and temporal clear corneal incisions of uneventful phacoemulsification and in-the-bag intraocular lens implantation on intraocular pressure control and the bleb morphology in eyes that have undergone previous successful trabeculectomy. METHODS:In this Prospectiv...
journal_title：BMC ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12886-017-0500-9
更新日期：2017-06-26 00:00:00
abstract：BACKGROUND:To evaluate the safety and effectiveness of the Visian Implantable Collamer Lens (ICL) implantation in high myopic patients with inactive Graves' ophthalmopathy (GO) by observing the changes of choroidal thickness (CT). METHODS:Eight patients (16 eyes) with high myopia accompanied with inactive GO were sele...
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更新日期：2020-08-25 00:00:00
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journal_title：BMC ophthalmology
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doi：10.1186/s12886-015-0118-8
更新日期：2015-10-02 00:00:00
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pub_type： 杂志文章,评审
doi：10.1186/s12886-016-0282-5
更新日期：2016-07-11 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via the original article. ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,已发布勘误
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更新日期：2021-01-06 00:00:00
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pub_type： 杂志文章
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更新日期：2018-08-23 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-13-16
更新日期：2013-04-19 00:00:00
abstract：BACKGROUND:Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic until now. Acetaldehyde dehydrogenase 2 (ALDH2), a major enzyme involved in aldehyde detoxification, h...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-1330-8
更新日期：2020-02-18 00:00:00
abstract：BACKGROUND:Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist called cryosim-3 (C3, 1-diisopropylphosphorylnonane) which selectively activates TRPM8 (linked to co...
journal_title：BMC ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12886-017-0495-2
更新日期：2017-06-26 00:00:00
abstract：BACKGROUND:To evaluate the 6-month clinical outcomes of Flexivue Microlens refractive corneal inlay in emmetropic patients in Asia for the surgical compensation of presbyopia. METHODS:In this retrospective study, corneal inlay implantation was done using a femtosecond laser. The follow-up period was 6 months. Near/int...
journal_title：BMC ophthalmology
pub_type： 杂志文章
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更新日期：2019-03-05 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12886-016-0358-2
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journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1186/1471-2415-11-13
更新日期：2011-06-13 00:00:00
abstract：BACKGROUND:Graves' disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves' Ophthalmopathy. Not all patients respond well to the standard therapy of systemic glucocorticoid admini...
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pub_type： 杂志文章
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pub_type： 杂志文章,meta分析
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2020-07-11 00:00:00
abstract：BACKGROUND:To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea. METHODS:A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-4
更新日期：2014-01-10 00:00:00
abstract：BACKGROUND:Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0298-x
更新日期：2016-07-19 00:00:00
abstract：BACKGROUND:Currently, various types of toric intraocular lenses (IOL) have been manufactured and can be divided into three types according to the location of correction component; front-toric IOL (correction on anterior IOL surface), back-toric IOL (correction on posterior IOL surface), and bi-toric IOL (correction on ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01439-4
更新日期：2020-04-28 00:00:00
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pub_type： 杂志文章
doi：10.1186/1471-2415-14-165
更新日期：2014-12-23 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0571-7
更新日期：2017-10-02 00:00:00
abstract：BACKGROUND:Surgery for trichiasis is one of the pillars of the World Health Organization's strategy for global elimination of trachoma as a public health problem. A high incidence of post-operative trichiasis or other poor surgical outcomes could jeopardize these efforts. In this review, we aimed to summarize the repor...
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pub_type： 杂志文章
doi：10.1186/s12886-020-01564-0
更新日期：2020-11-17 00:00:00
abstract：BACKGROUND:The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it's not the same as regards the active compounds themselves. The purpose of our study was to compare Ocular Surface Disease (OSD) signs and symptoms of Tafluprost 0.0015% versu...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0534-z
更新日期：2017-08-03 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-015-0109-9
更新日期：2015-09-11 00:00:00
