Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes.

abstract：BACKGROUND:To present a case report of a patient with a mixed choroidal neovascular membrane (CNV) with an asymmetric response to ranibizumab diagnosed on optical coherence tomography angiography (OCTa). CASE PRESENTATION:A 61-year-old male was referred to our department in September 2017 due to decreased vision in hi...

journal_title：BMC ophthalmology

authors： Pencak M,Veith M

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND:To investigate the differences in refraction, accommodative factors, visual parameters, and subjective symptoms after using two types of virtual reality (VR) content with different depths of perception. METHODS:Twenty-three volunteers, who played VR games in two modes (immersive and non-immersive) for 30 mi...

journal_title：BMC ophthalmology

authors： Yoon HJ,Kim J,Park SW,Heo H

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes...

journal_title：BMC ophthalmology

authors： Song WP,Zheng S,Yao HJ,Zhou XF,Li R,Zhang CY,Zhao JY,Wang LW,Shao RG,Li L

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Patients' feedback is of great importance in health care policy decisions. The Consumer Quality Index Cataract Questionnaire (CQI Cataract) was used to measure patients' experiences with quality of care after a cataract operation. This study aims to evaluate the reliability and the dimensional structure of t...

journal_title：BMC ophthalmology

authors： Stubbe JH,Brouwer W,Delnoij DM

更新日期：2007-09-19 00:00:00

abstract：BACKGROUND:To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma. CASE PRESENTATION:We present a case of a 94-year-old male with choroidal melanoma of the right eye imaged with MRI and ocular ultrasound to aid in the detection of extrascleral exte...

journal_title：BMC ophthalmology

authors： Jacobsen BH,Ricks C,Harrie RP

更新日期：2018-12-12 00:00:00

abstract：BACKGROUND:An eye injury that causes no light perception (NLP) typically carries an unfavorable prognosis, and NLP because of trauma is a common indication for enucleation. With advances in vitreoretinal surgical techniques, however, the indication for enucleation is no longer determined by posttrauma NLP vision alone....

journal_title：BMC ophthalmology

authors： Agrawal R,Wei HS,Teoh S

更新日期：2012-06-19 00:00:00

abstract：BACKGROUND:To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world settings. METHODS:In this retrospective, observational, multicentre study in Slovenia, medical reco...

journal_title：BMC ophthalmology

authors： Jaki Mekjavić P,Gregorčič B,Oberč C,Podgoršek S

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:P66Shc is partially localised within the mitochondrial fraction. It is primarily related to the generation of mitochondrial reactive oxygen species and apoptosis. Based on previous studies, we hypothesize that in the retina, p66Shc may exist and affect the development of diabetic retinopathy. The purpose of ...

journal_title：BMC ophthalmology

authors： Zhao MH,Hu J,Li S,Wu Q,Lu P

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the genetic cause and describe the clinical phenotype of Schnyder corneal dystrophy (SCD) in six unrelated probands. METHODS:We identified two white Czech, two white British and two South Asian families with a clinical diagnosis of SCD. Ophthalmic assessment include...

journal_title：BMC ophthalmology

authors： Evans CJ,Dudakova L,Skalicka P,Mahelkova G,Horinek A,Hardcastle AJ,Tuft SJ,Liskova P

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:To predict the effectiveness of topical glaucoma medications based on initial uniocular and binocular treatment. To test a traditional hypothesis that effectiveness following a uniocular trial is associated with the change in IOP in the initially treated eye minus the change in the initially untreated eye. T...

journal_title：BMC ophthalmology

authors： Leffler CT,Amini L

更新日期：2007-10-05 00:00:00

abstract：BACKGROUND:Epidemic keratoconjunctivitis (EKC) is one of the most common eye infections worldwide. The analysis of clinical manifestations in different age groups help better know the disease. This study aims to provide more detailed analysis of 272 cases of EKC in 8 years, describe the differences of the clinical feat...

journal_title：BMC ophthalmology

authors： Hou W,Sun X,Feng J,Zhang Y,Wang Z

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:Bone marrow transplantation retinopathy is a rare condition affecting the posterior pole. The purpose of this case report is to highlight the possible risk factors and clinical features. CASE PRESENTATION:A 19y old male with relapsed and refractory acute lymphoblastic leukaemia was admitted under haematolog...

journal_title：BMC ophthalmology

authors： Butt F,McKibbin M

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND:Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes. Our present study was to measure the cone IZ area by optical coherence tomography (OCT),...

journal_title：BMC ophthalmology

authors： Gu R,Deng G,Jiang Y,Jiang C,Xu G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, cornea...

journal_title：BMC ophthalmology

authors： Bair H,Lin CJ,Lai CT,Hsia NY,Tsai YY

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:The eMERGE (electronic MEdical Records and Genomics) network, funded by the National Human Genome Research Institute, is a national consortium formed to develop, disseminate, and apply approaches to research that combine DNA biorepositories with electronic health record (EHR) systems for large-scale, high-th...

journal_title：BMC ophthalmology

authors： Waudby CJ,Berg RL,Linneman JG,Rasmussen LV,Peissig PL,Chen L,McCarty CA

更新日期：2011-11-11 00:00:00

abstract：BACKGROUND:To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitre...

journal_title：BMC ophthalmology

authors： Liu J,Chen Y,Wang S,Zhang X,Zhao P

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:Graves' disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves' Ophthalmopathy. Not all patients respond well to the standard therapy of systemic glucocorticoid admini...

journal_title：BMC ophthalmology

authors： Rau A,Klopfer M,Rommel N,Rau-Fornefeld M,Kolk A

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:Although most patients with visual impairment due to corneal diseases can be treated successfully with surgery, some require visual rehabilitation to restore reading ability. To evaluate the best LVAs especially in terms of reading speed and characterize this specific patient group we performed a prospective...

journal_title：BMC ophthalmology

authors： Oeverhaus M,Dekowski D,Hirche H,Esser J,Schaperdoth-Gerlings B,Eckstein A

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:Acute acquired comitant esotropia (AACE) is a type of strabismus characterized by a sudden onset of large angle esotropia with diplopia, which often occurs in children after infancy, teenagers, and young adolescents. However, studies on the surgical outcomes of only adults are rare. The purpose of this artic...

journal_title：BMC ophthalmology

authors： Kim DH,Noh HJ

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:To report patients with age-related macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributable to geographic atrophy (GA) or RPE-tears with overlying preserved photoreceptor layers. METHODS:Multimodal imaging case-series evaluating the course of atypical RPE- defects...

journal_title：BMC ophthalmology

authors： Giannakaki-Zimmermann H,Querques G,Munch IC,Shroff D,Sarraf D,Chen X,Cunha-Souza E,Mrejen S,Capuano V,Rodrigues MW,Gupta C,Ebneter A,Zinkernagel MS,Munk MR

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation. CASE PRESENTATION:A 56-year-old male patient presented at our outpatient clinic after becoming aware of dec...

journal_title：BMC ophthalmology

authors： Kohmoto R,Kobayashi T,Sato T,Kimura D,Fukumoto M,Tajiri K,Kida T,Ikeda T

更新日期：2017-12-19 00:00:00

abstract：PURPOSE:Outcome measurements currently used in chronic uveitis care fail to cover the full patient perspective. The aim of this study is to develop a conceptual model of the factors that adult patients with chronic uveitis consider to be important when evaluating the impact of their disease and treatment. METHODS:A qu...

journal_title：BMC ophthalmology

authors： Stolk-Vos AC,Kasigar H,Nijmeijer KJ,Missotten TO,Busschbach JJ,van de Klundert JJ,Kranenburg LW

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:Artificial iris anterior chamber implants were originally developed for therapeutic purposes but have been used recently for the cosmetic alteration of eye colour. There is a growing body of evidence surrounding their associated risks. We report a case presenting with complications secondary to bilateral New...

journal_title：BMC ophthalmology

authors： Shweikh Y,Ameen S,Mearza A

更新日期：2015-08-08 00:00:00

abstract：BACKGROUND:Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. METHODS:PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically ...

journal_title：BMC ophthalmology

authors： Meng B,Zhao L,Yin Y,Li H,Wang X,Yang X,You R,Wang J,Zhang Y,Wang H,Du R,Wang N,Zhan S,Wang Y

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery. METHODS:A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) aft...

journal_title：BMC ophthalmology

authors： Chen H,Wu Z,Chen Y,He M,Wang J

更新日期：2018-03-23 00:00:00

abstract：BACKGROUND:To assess the efficacy of the intravitreal (IVT) injection of Triamcinolone Acetonide (TA) as compared to posterior subtenon (SBT) capsule injection for the treatment of cystoid diabetic macular edema. METHODS:Fourteen patients with type II diabetes mellitus and on insulin treatment, presenting diffuse cyst...

journal_title：BMC ophthalmology

authors： Cellini M,Pazzaglia A,Zamparini E,Leonetti P,Campos EC

更新日期：2008-03-17 00:00:00

abstract：:Although the mechanism of dry eye disease is not clearly understood, it is certain that inflammation and the immune response play a major role in determining the health of the ocular surface in dry eye patients. Accurate ocular surface characterization during the early stages of dry eye disease is critical for success...

journal_title：BMC ophthalmology

authors： Na KS,Hwang KY,Lee HS,Chung SH,Mok JW,Joo CK

更新日期：2015-12-17 00:00:00

abstract：BACKGROUND:Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular pressure (IOP)-lowering medication change rates in patients newly treated with latanoprost or travoprost-...

journal_title：BMC ophthalmology

authors： Fain JM,Kotak S,Mardekian J,Bacharach J,Edward DP,Rauchman S,Brevetti T,Fox JL,Lovelace C

更新日期：2011-06-13 00:00:00

abstract：BACKGROUND:To understand the clinical and economic outcomes of treatments for managing complications of ischemic central retinal vein occlusion (iCRVO). METHODS:We conducted a systematic literature review by searching multiple databases and ophthalmology conferences from 2004 to 2015. Studies published in English lang...

journal_title：BMC ophthalmology

authors： Bradshaw SE,Gala S,Nanavaty M,Shah A,Mwamburi M,Kefalas P

更新日期：2016-07-11 00:00:00

abstract：BACKGROUND:The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it's not the same as regards the active compounds themselves. The purpose of our study was to compare Ocular Surface Disease (OSD) signs and symptoms of Tafluprost 0.0015% versu...

journal_title：BMC ophthalmology

authors： Rolle T,Spinetta R,Nuzzi R

更新日期：2017-08-03 00:00:00