Abstract：
BACKGROUND:Artificial iris anterior chamber implants were originally developed for therapeutic purposes but have been used recently for the cosmetic alteration of eye colour. There is a growing body of evidence surrounding their associated risks. We report a case presenting with complications secondary to bilateral NewColorIris® implants, including the first report of pressure-induced stromal keratopathy in this context. CASE PRESENTATION:A thirty-eight year old South American man presented as an emergency in the UK with best corrected visual acuities of 1/60 OD and 6/18 OS, bilateral corneal decompensation, lens opacities and raised intraocular pressures 4 years following bilateral NewColorIris® implantation in Panama. Anterior segment optical coherence tomography demonstrated the direct apposition of the implant with the iris and iridocorneal angle, together with pressure-induced stromal keratopathy with a fluid interface between the corneal stroma and previous laser-assisted in situ keratomileusis flaps. We describe the successful combined medical and surgical management in this case to yield a final visual acuity 6/12 in both eyes. CONCLUSION:Artificial iris anterior chamber implants are associated with sight-threatening complications that can present years after their implantation. We caution against their use for the cosmetic alteration of eye colour.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Shweikh Y,Ameen S,Mearza Adoi
10.1186/s12886-015-0084-1subject
Has Abstractpub_date
2015-08-08 00:00:00pages
97issn
1471-2415pii
10.1186/s12886-015-0084-1journal_volume
15pub_type
杂志文章abstract：PURPOSE:Outcome measurements currently used in chronic uveitis care fail to cover the full patient perspective. The aim of this study is to develop a conceptual model of the factors that adult patients with chronic uveitis consider to be important when evaluating the impact of their disease and treatment. METHODS:A qu...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01388-y
更新日期：2020-03-30 00:00:00
abstract：BACKGROUND:Retinopathy of Prematurity (ROP) is one of the most common causes of childhood blindness worldwide. Comparisons of anti-VEGF and laser treatments in ROP are relatively lacking, and the data are scattered and limited. The objective of this meta-analysis is to compare the efficacy of both treatments in type-1 ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1186/s12886-018-0685-6
更新日期：2018-01-30 00:00:00
abstract：BACKGROUND:This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. METHODS:In this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0503-6
更新日期：2017-07-04 00:00:00
abstract：BACKGROUND:To evaluate the efficacy and safety of intravitreal conbercept (KH902) as the primary treatment of choroidal neovascularization secondary to punctate inner choroidopathy. METHODS:This study was a retrospective, consecutive, observational case series. We reviewed medical records of 16 eyes (16 patients) with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0481-8
更新日期：2017-06-12 00:00:00
abstract：BACKGROUND:To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery. METHODS:Nonrandomized clinical trial. Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to Septe...
journal_title：BMC ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1186/s12886-019-1068-3
更新日期：2019-02-21 00:00:00
abstract：BACKGROUND:In this analysis, we aimed to systematically compare the complications which were associated with femtosecond laser-assisted cataract surgery (FLACS) versus the conventional phacoemulsification surgery (CPE). METHODS:Commonly used search databases, specifically MEDLINE, Cochrane Central, EMBASE, and http://...
journal_title：BMC ophthalmology
pub_type： 杂志文章,meta分析
doi：10.1186/s12886-019-1190-2
更新日期：2019-08-09 00:00:00
abstract：BACKGROUND:To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play an important role in the pathophysiology of this case. CASE PRESENTATION:A 9 year-old male with ac...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-30
更新日期：2011-11-02 00:00:00
abstract：BACKGROUND:Stress-induced activation of the sympathetic nervous system leads to a cascade of metabolic reactions. Emotional stress is a more specific form of stress in which the stressor is a psychological response to a situation subjectively perceived as traumatic. Stress hormones can have a wide range of effects on t...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1075-4
更新日期：2019-03-08 00:00:00
abstract：BACKGROUND:Congenital cataract is the most frequent cause of blindness during infancy or early childhood. To date, more than 40 loci associated with congenital cataract have been identified, including at least 26 genes on different chromosomes associated with inherited cataract. This present study aimed to identify the...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0476-5
更新日期：2017-05-19 00:00:00
abstract：BACKGROUND:To evaluate the prognosis of Chinese patients with lacrimal gland adenoid cystic carcinoma treated with eye-sparing surgery and adjuvant multimodal therapy. METHODS:The study included 24 consecutive patients with lacrimal gland adenoid cystic carcinoma treated at the Ninth People's Hospital of Shanghai from...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1110-5
更新日期：2019-06-08 00:00:00
abstract：BACKGROUND:To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up. METHODS:The study included 62 eyes that underwent successful PPV with SF6 t...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1120-3
更新日期：2019-05-24 00:00:00
abstract：BACKGROUND:To understand which irregular corneal parameters determine the visual quality in keratoconus subjects. METHODS:The cross-sectional study examined the eyes of 44 subjects, graded from the first to third keratoconus stages by Amsler-Krumeich classification. We obtained measurements in two ways: (a) by project...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01737-x
更新日期：2020-11-26 00:00:00
abstract：BACKGROUND:This multicentre, retro-prospective real-world study evaluated the visual, refractive and safety outcomes of a monofocal lens 1 year after implantation in cataract patients with or without pre-existing ocular pathologies. METHODS:Records from 4 centres in Germany and Sweden were reviewed to select eyes with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01493-y
更新日期：2020-06-11 00:00:00
abstract：BACKGROUND:To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS:This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0783-5
更新日期：2018-05-09 00:00:00
abstract：BACKGROUND:P66Shc is partially localised within the mitochondrial fraction. It is primarily related to the generation of mitochondrial reactive oxygen species and apoptosis. Based on previous studies, we hypothesize that in the retina, p66Shc may exist and affect the development of diabetic retinopathy. The purpose of ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0724-3
更新日期：2018-02-27 00:00:00
abstract：BACKGROUND:To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. METHODS:This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. I...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0719-0
更新日期：2018-02-20 00:00:00
abstract：BACKGROUND:To present the follow-up outcomes of a modified technique of transscleral suture fixation of posterior chamber intraocular lens (PCIOL) in eyes with inadequate capsule support. METHODS:A retrospective chart review of 21 patients underwent transscleral suture fixation of a foldable 3-looped haptics one-piece...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1113-2
更新日期：2019-05-09 00:00:00
abstract：BACKGROUND:Highly aggressive Burkitt lymphoma (BL) with rapidly progressive painful proptosis of the right eye is rarely encountered. CASE PRESENTATION:A 31-year-old Caucasian female presented with rapidly progressive painful proptosis of the right eye and poor visual acuity. Diagnostic Computer tomography, magnetic r...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-109
更新日期：2014-09-08 00:00:00
abstract：BACKGROUND:To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy. METHODS:Neonatal C57BL/6 mice were exposed in hyperoxygen and returned to room air to develop oxygen-induced ret...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1292-x
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abstract：BACKGROUND:To report a patient who presented with bluish scleral discoloration, keratoconus, and progressive high myopia. CASE PRESENTATION:A 6-year-old Chinese female patient presented with a significant bluish discoloration of the sclera in both eyes and extreme corneal thinning with anterior corneal protrusion. Gen...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-018-0903-2
更新日期：2018-09-18 00:00:00
abstract：BACKGROUND:The presence of an intraocular cilium is very rare and the response of the eye to the cilium is variable. We present the case of a patient with a cilium found in the vitreous cavity during vitrectomy for rhegmatogenous retinal detachment 40 years following penetrating eye injury. To our knowledge, this is th...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-015-0010-6
更新日期：2015-03-12 00:00:00
abstract：BACKGROUND:The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. METHODS:The present study was a retros...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0271-8
更新日期：2016-07-08 00:00:00
abstract：BACKGROUND:To assess the efficacy of the intravitreal (IVT) injection of Triamcinolone Acetonide (TA) as compared to posterior subtenon (SBT) capsule injection for the treatment of cystoid diabetic macular edema. METHODS:Fourteen patients with type II diabetes mellitus and on insulin treatment, presenting diffuse cyst...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-8-5
更新日期：2008-03-17 00:00:00
abstract：BACKGROUND:The signaling pathway of epithelial to mesenchymal transition (EMT) is regulated by c-Src kinase in many cells. The purpose of this study was to investigate the effects of c-Src kinase on EMT of human lens epithelial cells in vivo stimulated by different factors. METHODS:Human lens epithelial cells, HLE-B3,...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1229-4
更新日期：2019-11-08 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-12-2
更新日期：2012-01-24 00:00:00
abstract：BACKGROUND:This study aimed to investigate patient adherence to face-down positioning (FDP) and non-supine positioning (NSP) following vitrectomy with gas tamponade for treating macular holes (MHs). METHODS:Nursing records of 92 patients who underwent vitrectomy with gas tamponade for small-diameter (diameter < 400 μm...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0979-8
更新日期：2018-12-14 00:00:00
abstract：BACKGROUND:Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0298-x
更新日期：2016-07-19 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1129-7
更新日期：2019-06-17 00:00:00
abstract：BACKGROUND:A few case reports have described accidental eye injuries caused by fish hooks. The severity of ocular injuries is dependent on the involved ocular structures. Severe ocular injuries due to fish hooks are rare. We describe open globe and penetrating eyelid injuries from fish hooks at the Baltic Sea. METHODS...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1040-2
更新日期：2019-01-21 00:00:00
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journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-14
更新日期：2011-06-14 00:00:00
