Advances in the support of respiratory failure: putting all the evidence together.

abstract：BACKGROUND:Oliguria is one of the leading triggers of fluid loading in patients in the intensive care unit (ICU). The purpose of this study was to assess the predictive value of urine Na(+) (uNa(+)) and other routine urine biomarkers for cardiac fluid responsiveness in oliguric ICU patients. METHODS:We conducted a pro...

journal_title：Critical care (London, England)

authors： Legrand M,Le Cam B,Perbet S,Roger C,Darmon M,Guerci P,Ferry A,Maurel V,Soussi S,Constantin JM,Gayat E,Lefrant JY,Leone M,support of the AZUREA network.

更新日期：2016-05-29 00:00:00

abstract：BACKGROUND:The incidence of seizures in intensive care units ranges from 3.3% to 34%. It is therefore often necessary to initiate or continue anticonvulsant drugs in this setting. When a new anticonvulsant is initiated, drug factors, such as onset of action and side effects, and patient factors, such as age, renal, and...

journal_title：Critical care (London, England)

authors： Farrokh S,Tahsili-Fahadan P,Ritzl EK,Lewin JJ 3rd,Mirski MA

更新日期：2018-06-07 00:00:00

abstract：:The great majority of infections caused by the pandemic variant of the influenza virus (nvH1N1) are self-limited, but a small percentage of patients develop severe symptoms requiring hospitalization. Bermejo-Martin and colleagues have presented a pilot study describing the differences in the early immune response for ...

journal_title：Critical care (London, England)

authors： de Castro IF,Guzmán-Fulgencio M,García-Alvarez M,Resino S

更新日期：2010-01-01 00:00:00

abstract：:Valproic acid (VPA) is a broad-spectrum antiepileptic drug and is usually well tolerated, but rare serious complications may occur in some patients receiving VPA chronically, including haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (V...

journal_title：Critical care (London, England)

authors： Lheureux PE,Penaloza A,Zahir S,Gris M

更新日期：2005-10-05 00:00:00

abstract：INTRODUCTION:Mechanical ventilators are increasingly used in critical care units. However, they can cause lung injury, including pulmonary edema. Our previous studies indicated that γ-aminobutyric acid (GABA) receptors are involved in alveolar-fluid homeostasis. The present study investigated the role of GABA receptors...

journal_title：Critical care (London, England)

authors： Chintagari NR,Liu L

更新日期：2012-12-12 00:00:00

abstract：:Lobar atelectasis is a common problem caused by a variety of mechanisms including resorption atelectasis due to airway obstruction, passive atelectasis from hypoventilation, compressive atelectsis from abdominal distension and adhesive atelectasis due to increased surface tension. However, evidence-based studies on th...

journal_title：Critical care (London, England)

authors： Schindler MB

更新日期：2005-08-01 00:00:00

abstract：INTRODUCTION:During septic shock, resistance to the haemodynamic effects of catecholamine vasopressors and inotropes is a well-recognised marker of mortality risk. However, the specific cardiovascular or metabolic response elements that are most closely associated with outcome have not been well defined. The objective ...

journal_title：Critical care (London, England)

authors： Kumar A,Schupp E,Bunnell E,Ali A,Milcarek B,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Patients admitted to intensive care following surgery for faecal peritonitis present particular challenges in terms of clinical management and risk assessment. Collaborating surgical and intensive care teams need shared perspectives on prognosis. We aimed to determine the relationship between dynamic asses...

journal_title：Critical care (London, England)

authors： Tridente A,Clarke GM,Walden A,Gordon AC,Hutton P,Chiche JD,Holloway PA,Mills GH,Bion J,Stüber F,Garrard C,Hinds C,GenOSept Investigators.

更新日期：2015-05-05 00:00:00

abstract：INTRODUCTION:Despite experimental evidence, clinical demonstration of acute state of oxidative stress and inflammation during post-cardiac arrest syndrome is lacking. Plasma level of thioredoxin (TRX), a redox-active protein induced under conditions of oxidative stress and inflammation, is increased in various critical...

journal_title：Critical care (London, England)

authors： Mongardon N,Lemiale V,Borderie D,Burke-Gaffney A,Perbet S,Marin N,Charpentier J,Pène F,Chiche JD,Mira JP,Cariou A

更新日期：2013-01-29 00:00:00

abstract：INTRODUCTION:Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to evaluate a four-region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care unit. METHODS:Fift...

journal_title：Critical care (London, England)

authors： Enghard P,Rademacher S,Nee J,Hasper D,Engert U,Jörres A,Kruse JM

更新日期：2015-02-06 00:00:00

abstract：:The use of corticosteroids in septic shock remains controversial. It has been demonstrated that high doses of steroids (30 mg/kg methylprednisolone) for short periods of time are not beneficial. More recent studies using smaller doses (200-300 mg/day hydrocortisone) for longer periods of time have shown beneficial eff...

journal_title：Critical care (London, England)

authors： Goodman S,Sprung CL,International Sepsis Forum.

更新日期：2002-10-01 00:00:00

abstract：:Tracheal reintubation is a common event in critical care. Elmer and colleagues provide the first comparison of complication rates of initial and subsequent reintubation(s) during the same hospitalization. Their work shows an increased risk of complications associated with reintubation, in particular hypoxemia and hypo...

journal_title：Critical care (London, England)

authors： Parotto M,Cooper RM

更新日期：2015-03-27 00:00:00

abstract：:The use of controlled mechanical ventilation (CMV) in patients who experience weaning failure after a spontaneous breathing trial or after extubation is a strategy based on the premise that respiratory muscle fatigue (requiring rest to recover) is the cause of weaning failure. Recent evidence, however, does not suppor...

journal_title：Critical care (London, England)

authors： Vassilakopoulos T,Zakynthinos S,Roussos C

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Our objective was to evaluate the impact of gastric versus post-pyloric feeding on the incidence of pneumonia, caloric intake, intensive care unit (ICU) length of stay (LOS), and mortality in critically ill and injured ICU patients. METHOD:Data sources were Medline, Embase, Healthstar, citation review of re...

journal_title：Critical care (London, England)

authors： Marik PE,Zaloga GP

更新日期：2003-06-01 00:00:00

abstract：:Providing effective analgesia and adequate sedation is a generally accepted goal of intensive care medicine. Due to its rapid, organ independent and predictable metabolism the short acting opioid remifentanil might be particularly useful for analgesia-based sedation in the intensive care unit (ICU). This hypothesis wa...

journal_title：Critical care (London, England)

authors： Kuhlen R,Putensen C

更新日期：2004-02-01 00:00:00

abstract：:In this month's issue of Critical Care, Determann and colleagues report the results of a randomized controlled trial comparing the effects of mechanical ventilation (MV) with two tidal volumes (6 versus 10 ml/kg predicted body weight) on cytokine levels in lung lavage fluid and plasma as a surrogate for early identifi...

journal_title：Critical care (London, England)

authors： Villar J,Slutsky AS

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Delayed patient admission to the intensive care unit (ICU) due to lack of bed availability is a common problem, but the effect on patient outcome is not fully known. METHODS:A retrospective study was performed using departmental computerised records to determine the effect of delayed ICU admission and tem...

journal_title：Critical care (London, England)

authors： O'Callaghan DJ,Jayia P,Vaughan-Huxley E,Gribbon M,Templeton M,Skipworth JR,Gordon AC

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:Sedation overuse is frequent and possibly associated with poor outcomes in the intensive care unit (ICU) patients. However, the association of early oversedation with clinical outcomes has not been thoroughly evaluated. The aim of this study was to assess the association of early sedation strategies with o...

journal_title：Critical care (London, England)

authors： Tanaka LM,Azevedo LC,Park M,Schettino G,Nassar AP,Réa-Neto A,Tannous L,de Souza-Dantas VC,Torelly A,Lisboa T,Piras C,Carvalho FB,Maia Mde O,Giannini FP,Machado FR,Dal-Pizzol F,de Carvalho AG,dos Santos RB,Tierno PF,

更新日期：2014-07-21 00:00:00

abstract：INTRODUCTION:Patients with acute-on-chronic liver failure show an aggravated hyperdynamic circulation. We evaluated, in a controlled manner, potential changes in systemic haemodynamics induced by the molecular adsorbent recirculating system (MARS) and the Prometheus system liver detoxification devices in a group of pat...

journal_title：Critical care (London, England)

authors： Laleman W,Wilmer A,Evenepoel P,Elst IV,Zeegers M,Zaman Z,Verslype C,Fevery J,Nevens F

更新日期：2006-01-01 00:00:00

abstract：:Mechanical ventilation associated lung injury (VALI) negatively impacts the outcomes of critically ill patients. Research during the past two decades has led to a better understanding of key physiologic mechanisms of injury, yet uncertainty over the topographical distribution of these mechanisms continues to fuel cont...

journal_title：Critical care (London, England)

authors： Oeckler RA,Hubmayr RD

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Neurocritical illness is a growing healthcare problem with profound socioeconomic effects. We assessed differences in healthcare costs and long-term outcome for different forms of neurocritical illnesses treated in the intensive care unit (ICU). METHODS:We used the prospective Finnish Intensive Care Consort...

journal_title：Critical care (London, England)

authors： Raj R,Bendel S,Reinikainen M,Hoppu S,Laitio R,Ala-Kokko T,Curtze S,Skrifvars MB

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:Survivors of an acute critical illness with continuing organ dysfunction and uncontrolled inflammatory responses are prone to become chronically critically ill. As mental sequelae, a post-traumatic stress disorder and an associated decrease in the health-related quality of life (QoL) may occur, not only in t...

journal_title：Critical care (London, England)

authors： Wintermann GB,Petrowski K,Weidner K,Strauß B,Rosendahl J

更新日期：2019-02-08 00:00:00

abstract：:Investigations on the relationship between sepsis, brain dysfunction, and cerebral perfusion are methodologically very difficult to perform. It is important to interpret the results of such studies in view of our limited ability to diagnose and quantify brain dysfunction and to consider our limited understanding of th...

journal_title：Critical care (London, England)

authors： Steiner LA

更新日期：2008-01-01 00:00:00

abstract：:Even more than in previous disasters, Katrina has proven itself to be a testing ground for a plethora of new technologies. Although not all of these technologies did immediately save lives, in this regard a number of them exhibited considerable potential for the future, and hence there is a need to include them in fut...

journal_title：Critical care (London, England)

authors： Leitl E

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Admission blood glucose (BG) level is a predictor of mortality in patients with ST-segment elevation myocardial infarction (STEMI). However, limited data are available relating admission BG to mortality in patients with STEMI complicated by cardiogenic shock, and it is not known whether diabetic status has...

journal_title：Critical care (London, England)

authors： Yang JH,Song PS,Song YB,Hahn JY,Choi SH,Choi JH,Lee SH,Jeong MH,Kim YJ,Gwon HC

更新日期：2013-10-03 00:00:00

abstract：BACKGROUND:Higher inspiratory airway pressures are associated with worse outcomes in mechanically ventilated patients with the acute respiratory distress syndrome (ARDS). This relationship, however, has not been well investigated in patients without ARDS. We hypothesized that higher driving pressures (ΔP) and plateau p...

journal_title：Critical care (London, England)

authors： Sahetya SK,Mallow C,Sevransky JE,Martin GS,Girard TD,Brower RG,Checkley W,Society of Critical Care Medicine Discovery Network Critical Illness Outcomes Study Investigators.

更新日期：2019-11-21 00:00:00

abstract：:The early recognition and management of sepsis remain the greatest challenges in the field of critical care medicine. Endothelial injury is one of the hallmarks of sepsis, leading to capillary leak, microcirculatory dysfunction, organ failure, and eventual death in many critically ill patients. The angiogenic growth f...

journal_title：Critical care (London, England)

authors： Giuliano JS Jr,Wheeler DS

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Expert systems can help alleviate problems related to the shortage of human resources in critical care, offering expert advice in complex situations. Expert systems use contextual information to provide advice to staff. In mechanical ventilation, it is crucial for an expert system to be able to determine the...

journal_title：Critical care (London, England)

authors： Murias G,Montanyà J,Chacón E,Estruga A,Subirà C,Fernández R,Sales B,de Haro C,López-Aguilar J,Lucangelo U,Villar J,Kacmarek RM,Blanch L

更新日期：2016-08-14 00:00:00

abstract：:The first part of this review addresses the diagnosis and differential diagnosis of the primary vasculitides Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa. Prompt diagnosis and treatment of these conditions ensures an optimal prognosis. The development of assays fo...

journal_title：Critical care (London, England)

authors： Semple D,Keogh J,Forni L,Venn R

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Among critically ill patients with acute kidney injury (AKI) needing continuous renal replacement therapy (CRRT), the effect of convective (via continuous venovenous hemofiltration [CVVH]) versus diffusive (via continuous venovenous hemodialysis [CVVHD]) solute clearance on clinical outcomes is unclear. Ou...

journal_title：Critical care (London, England)

authors： Wald R,Friedrich JO,Bagshaw SM,Burns KE,Garg AX,Hladunewich MA,House AA,Lapinsky S,Klein D,Pannu NI,Pope K,Richardson RM,Thorpe K,Adhikari NK

更新日期：2012-10-24 00:00:00