Impact of post-traumatic stress symptoms on the health-related quality of life in a cohort study with chronically critically ill patients and their partners: age matters.

abstract：INTRODUCTION:Fractalkine is a chemokine implicated as a mediator in a variety of inflammatory conditions. Knowledge of fractalkine release in patients presenting with infection to the Intensive Care Unit (ICU) is highly limited. The primary objective of this study was to establish whether plasma fractalkine levels are ...

journal_title：Critical care (London, England)

authors： Hoogendijk AJ,Wiewel MA,van Vught LA,Scicluna BP,Belkasim-Bohoudi H,Horn J,Zwinderman AH,Klein Klouwenberg PM,Cremer OL,Bonten MJ,Schultz MJ,van der Poll T,MARS consortium.

更新日期：2015-11-25 00:00:00

abstract：: ...

journal_title：Critical care (London, England)

authors： Honore PM,De Bels D,Kugener L,Redant S,Attou R,Gallerani A,Spapen HD

更新日期：2019-01-09 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. METHODS:A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal...

journal_title：Critical care (London, England)

authors： Bassetti M,Giacobbe DR,Vena A,Trucchi C,Ansaldi F,Antonelli M,Adamkova V,Alicino C,Almyroudi MP,Atchade E,Azzini AM,Carannante N,Carnelutti A,Corcione S,Cortegiani A,Dimopoulos G,Dubler S,García-Garmendia JL,Girardis

更新日期：2019-06-14 00:00:00

abstract：INTRODUCTION:There are few data related to the effects of different sources of infection on outcome. We used the Sepsis Occurrence in Acutely ill Patients (SOAP) database to investigate differences in the impact of respiratory tract and abdominal sites of infection on organ failure and survival. METHODS:The SOAP study...

journal_title：Critical care (London, England)

authors： Volakli E,Spies C,Michalopoulos A,Groeneveld AB,Sakr Y,Vincent JL

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Following trauma, patients may suffer an overwhelming pro-inflammatory response and immune paralysis resulting in infection and multiple organ failure (MOF). Various potentially immunomodulative interventions have been tested. The objective of this study is to systematically review the randomized controlle...

journal_title：Critical care (London, England)

authors： Spruijt NE,Visser T,Leenen LP

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Severe hypoglycemia (blood glucose concentration (BG) < 40 mg/dL) is independently associated with an increased risk of mortality in critically ill patients. The association of milder hypoglycemia (BG < 70 mg/dL) with mortality is less clear. METHODS:Prospectively collected data from two observational coh...

journal_title：Critical care (London, England)

authors： Krinsley JS,Schultz MJ,Spronk PE,Harmsen RE,van Braam Houckgeest F,van der Sluijs JP,Mélot C,Preiser JC

更新日期：2011-07-25 00:00:00

abstract：INTRODUCTION:During septic shock, resistance to the haemodynamic effects of catecholamine vasopressors and inotropes is a well-recognised marker of mortality risk. However, the specific cardiovascular or metabolic response elements that are most closely associated with outcome have not been well defined. The objective ...

journal_title：Critical care (London, England)

authors： Kumar A,Schupp E,Bunnell E,Ali A,Milcarek B,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Simvastatin therapy for patients with acute respiratory distress syndrome (ARDS) has been shown to be safe and associated with minimal adverse effects, but it does not improve clinical outcomes. The aim of this research was to report on mortality and cost-effectiveness of simvastatin in patients with ARDS at...

journal_title：Critical care (London, England)

authors： Agus A,Hulme C,Verghis RM,McDowell C,Jackson C,O'Kane CM,Laffey JG,McAuley DF

更新日期：2017-05-17 00:00:00

abstract：BACKGROUND:Septic shock (SS) and cardiogenic shock (CS) are two types of circulatory shock with a different etiology. Several studies have described the molecular alterations in SS patients, whereas the molecular factors involved in CS have been poorly investigated. We aimed to assess in the whole blood of CS and SS pa...

journal_title：Critical care (London, England)

authors： Braga D,Barcella M,Herpain A,Aletti F,Kistler EB,Bollen Pinto B,Bendjelid K,Barlassina C

更新日期：2019-12-19 00:00:00

abstract：INTRODUCTION:Metformin-associated lactic acidosis (MALA) is a classic side effect of metformin and is known to be a severe disease with a high mortality rate. The treatment of MALA with dialysis is controversial and is the subject of many case reports in the literature. We aimed to assess the prevalence of MALA in a 16...

journal_title：Critical care (London, England)

authors： Peters N,Jay N,Barraud D,Cravoisy A,Nace L,Bollaert PE,Gibot S

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Intensive care medicine is a relatively young discipline that has rapidly grown into a full-fledged medical subspecialty. Intensivists are responsible for managing an ever-increasing number of patients with complex, life-threatening diseases. Several factors may influence their performance, including age, tr...

journal_title：Critical care (London, England)

authors： Castro R,Nin N,Ríos F,Alegría L,Estenssoro E,Murias G,Friedman G,Jibaja M,Ospina-Tascon G,Hurtado J,Marín MDC,Machado FR,Cavalcanti AB,Dubin A,Azevedo L,Cecconi M,Bakker J,Hernandez G,Latin-American Intensive Care Net

更新日期：2018-02-21 00:00:00

abstract：INTRODUCTION:This study hypothesised that a reduction of sound during the night using earplugs could be beneficial in the prevention of intensive care delirium. Two research questions were formulated. First, does the use of earplugs during the night reduce the onset of delirium or confusion in the ICU? Second, does the...

journal_title：Critical care (London, England)

authors： Van Rompaey B,Elseviers MM,Van Drom W,Fromont V,Jorens PG

更新日期：2012-05-04 00:00:00

abstract：INTRODUCTION:Currently, little is known about the immunological characteristics of patients with avian influenza A (H7N9) virus infection. METHODS:The numbers and percentages of peripheral blood immune cells were measured in 27 patients with laboratory-confirmed H7N9 virus infection and 30 healthy controls (HCs). The ...

journal_title：Critical care (London, England)

authors： Wu W,Shi Y,Gao H,Liang W,Sheng J,Li L

更新日期：2014-03-24 00:00:00

abstract：:Malignant stroke occurs in a subgroup of patients suffering from ischemic cerebral infarction and is characterized by neurological deterioration due to progressive edema, raised intracranial pressure, and cerebral herniation. Decompressive craniectomy (DC) is a surgical technique aiming to open the "closed box" repres...

journal_title：Critical care (London, England)

authors： Beez T,Munoz-Bendix C,Steiger HJ,Beseoglu K

更新日期：2019-06-07 00:00:00

abstract：:Sepsis is characterized by a dysregulated immune response to infection leading to life-threatening organ dysfunction. Sepsis-induced liver injury is recognized as a powerful independent predictor of mortality in the intensive care unit. During systemic infections, the liver regulates immune defenses via bacterial clea...

journal_title：Critical care (London, England)

authors： Sun J,Zhang J,Wang X,Ji F,Ronco C,Tian J,Yin Y

更新日期：2020-10-19 00:00:00

abstract：INTRODUCTION:Lung protective ventilation requires low tidal volume and suitable positive end-expiratory pressure (PEEP). To date, few methods have been accepted for clinical use to set the appropriate PEEP. The aim of this study was to test the feasibility of PEEP titration guided by ventilation homogeneity using the g...

journal_title：Critical care (London, England)

authors： Zhao Z,Steinmann D,Frerichs I,Guttmann J,Möller K

更新日期：2010-01-01 00:00:00

abstract：:Sepsis, despite recent therapeutic progress, still carries unacceptably high mortality rates. The adrenergic system, a key modulator of organ function and cardiovascular homeostasis, could be an interesting new therapeutic target for septic shock. Beta-adrenergic regulation of the immune function in sepsis is complex ...

journal_title：Critical care (London, England)

authors： de Montmollin E,Aboab J,Mansart A,Annane D

更新日期：2009-01-01 00:00:00

abstract：:There is a paradigm shift happening for sepsis. Sepsis is no longer solely conceptualized as problem of individual patients treated in emergency departments and intensive care units but also as one that is addressed as public health issue with population- and systems-based solutions. We offer a conceptual framework fo...

journal_title：Critical care (London, England)

authors： Kempker JA,Wang HE,Martin GS

更新日期：2018-05-06 00:00:00

abstract：:Bacterial sepsis and septic shock are complex inflammatory disorders associated with a systemic inflammatory response syndrome. In the most severe cases of infection, an overzealous release of pro-inflammatory cytokines and inflammatory mediators by activated leukocytes, epithelial cells and endothelial cells, known a...

journal_title：Critical care (London, England)

authors： Souza-Fonseca-Guimaraes F,Cavaillon JM,Adib-Conquy M

更新日期：2013-08-27 00:00:00

abstract：INTRODUCTION:To investigate whether respiratory variation of inferior vena cava diameter (cIVC) predict fluid responsiveness in spontaneously breathing patients with acute circulatory failure (ACF). METHODS:Forty patients with ACF and spontaneous breathing were included. Response to fluid challenge was defined as a 15...

journal_title：Critical care (London, England)

authors： Muller L,Bobbia X,Toumi M,Louart G,Molinari N,Ragonnet B,Quintard H,Leone M,Zoric L,Lefrant JY,AzuRea group.

更新日期：2012-10-08 00:00:00

abstract：BACKGROUND:Intensive care unit (ICU) delirium is a frequent secondary neurological complication in critically ill patients undergoing prolonged mechanical ventilation. Quantitative pupillometry is an emerging modality for the neuromonitoring of primary acute brain injury, but its potential utility in patients at risk o...

journal_title：Critical care (London, England)

authors： Favre E,Bernini A,Morelli P,Pasquier J,Miroz JP,Abed-Maillard S,Ben-Hamouda N,Oddo M

更新日期：2020-02-24 00:00:00

abstract：:The rationale for the provision of nitrogen from proteins given via the enteral route or from intravenous amino acids is to boost the synthesis of muscle proteins, and thereby to limit the severity of intensive care unit-acquired weakness by the prevention of muscle loss. However, the optimal timing for supplemental n...

journal_title：Critical care (London, England)

authors： Preiser JC

更新日期：2018-10-25 00:00:00

abstract：INTRODUCTION:The aim of the present study was to investigate the relationship between the blood IL-6 level, the blood glucose level, and glucose control in septic patients. METHODS:This retrospective observational study in a general ICU of a university hospital included a total of 153 patients with sepsis, severe seps...

journal_title：Critical care (London, England)

authors： Nakamura M,Oda S,Sadahiro T,Watanabe E,Abe R,Nakada TA,Morita Y,Hirasawa H

更新日期：2012-12-12 00:00:00

abstract：INTRODUCTION:Management of daily activities in ICUs is challenging. ICU shift leaders, charge nurses and intensivists have to make several immediate ad hoc decisions to enable the fluent flow of ICU activities. Even though the management of ICU activities is quite well delineated by international consensus guidelines, ...

journal_title：Critical care (London, England)

authors： Lundgrén-Laine H,Kontio E,Perttilä J,Korvenranta H,Forsström J,Salanterä S

更新日期：2011-08-08 00:00:00

abstract：:Postoperative outcome is mainly influenced by ventricular function. Tests designed to identify myocardial ischemia alone will fail to detect cardiac failure and are thus inadequate as a screening test for identification of cardiac risk in noncardiac surgical patients. We find that the degree of cardiac failure is the ...

journal_title：Critical care (London, England)

authors： Older P,Hall A

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:In patients with severe sepsis and septic shock as cause of Intensive Care Unit (ICU) admission, we analyze the impact on mortality of adequate antimicrobial therapy initiated before ICU admission. METHODS:We conducted a prospective observational study enrolling patients admitted to the ICU with severe se...

journal_title：Critical care (London, England)

authors： Garnacho-Montero J,Gutiérrez-Pizarraya A,Escoresca-Ortega A,Fernández-Delgado E,López-Sánchez JM

更新日期：2015-08-27 00:00:00

abstract：:Considerable progress has been made in the past few years in the development of therapeutic interventions that can reduce mortality in sepsis. However, encouraging physicians to put the results of new studies into practice is not always simple. A roundtable was thus convened to provide guidance for clinicians on the i...

journal_title：Critical care (London, England)

authors： Vincent JL,Abraham E,Annane D,Bernard G,Rivers E,Van den Berghe G

更新日期：2002-12-01 00:00:00

abstract：:There has been a lot of debate about the concept of relative adrenocortical insufficiency (often defined as a reduced response to corticotropin) as a pathophysiological explanation of steroid effects in septic shock. Less is known about the prevalence of absolute adrenocortical insufficiency based on more usual defini...

journal_title：Critical care (London, England)

authors： Bollaert PE

更新日期：2008-01-01 00:00:00

abstract：:Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...

journal_title：Critical care (London, England)

authors： Schneider AG,Journois D,Rimmelé T

更新日期：2017-11-19 00:00:00

abstract：BACKGROUND:In order to improve assessment and outcome prediction in patients suffering from traumatic brain injury (TBI), cerebral protein levels in serum have been suggested as biomarkers of injury. However, despite much investigation, biomarkers have yet to reach broad clinical utility in TBI. This study is a 9-year ...

journal_title：Critical care (London, England)

authors： Thelin EP,Jeppsson E,Frostell A,Svensson M,Mondello S,Bellander BM,Nelson DW

更新日期：2016-09-08 00:00:00