Abstract:
:Malignant stroke occurs in a subgroup of patients suffering from ischemic cerebral infarction and is characterized by neurological deterioration due to progressive edema, raised intracranial pressure, and cerebral herniation. Decompressive craniectomy (DC) is a surgical technique aiming to open the "closed box" represented by the non-expandable skull in cases of refractory intracranial hypertension. It is a valuable modality in the armamentarium to treat patients with malignant stroke: the life-saving effect has been proven for both supratentorial and infratentorial DC in virtually all age groups. This leaves physicians with the difficult task to decide who will require early or preemptive surgery and who might benefit from postponing surgery until clear evidence of deterioration evolves. Together with the patient's relatives, physicians also have to ascertain whether the patient will have acceptable disability and quality of life in his or her presumed perception, based on preoperative predictions. This complex decision-making process can only be managed with interdisciplinary efforts and should be supported by continued research in the age of personalized medicine.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Beez T,Munoz-Bendix C,Steiger HJ,Beseoglu Kdoi
10.1186/s13054-019-2490-xsubject
Has Abstractpub_date
2019-06-07 00:00:00pages
209issue
1eissn
1364-8535issn
1466-609Xpii
10.1186/s13054-019-2490-xjournal_volume
23pub_type
杂志文章,评审相关文献
CRITICAL CARE文献大全abstract:INTRODUCTION:Lowering of hyperglycemia in the intensive care unit (ICU) is widely practiced. We investigated in which way glucose regulation, defined as mean glucose concentration during admission, is associated with ICU mortality in a medical and a surgical cohort. METHODS:Retrospective database cohort study includin...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc9369
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Neutrophil gelatinase-associated lipocalin (NGAL) is a promising novel biomarker that correlates with the severity and outcome of acute kidney injury (AKI). However, its prognostic utility during the late course of AKI, especially in patients that require renal replacement therapy (RRT) remains unknown. Th...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc8861
更新日期:2010-01-01 00:00:00
abstract::Percutaneous dilatation tracheostomy in the intensive care setting presents an increasingly important concept for establishing a large-bore tracheal airway with minimal surgical intervention. Over the last years, different technical solutions have been studied to assess their respective risks and benefits to determine...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc2968
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:Lung protective ventilation requires low tidal volume and suitable positive end-expiratory pressure (PEEP). To date, few methods have been accepted for clinical use to set the appropriate PEEP. The aim of this study was to test the feasibility of PEEP titration guided by ventilation homogeneity using the g...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc8860
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Candidemia is an opportunistic infection associated with high morbidity and mortality in patients hospitalized both inside and outside intensive care units (ICUs). Identification of patients at risk is crucial to ensure prompt antifungal therapy. We sought to assess risk factors for candidemia and death, bot...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-020-2766-1
更新日期:2020-03-18 00:00:00
abstract::Acute kidney injury (AKI) is now well recognized as an independent risk factor for increased morbidity and mortality, particularly when dialysis is needed. The wide variation in dialysis utilization contributes to a lack of consensus on what parameters should guide the decision to start dialysis. While the association...
journal_title:Critical care (London, England)
pub_type: 评论,信件
doi:10.1186/cc8199
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Multiple organ dysfunction syndrome (MODS) is a common complication of sepsis in mechanically ventilated patients with acute respiratory distress syndrome, but the links between mechanical ventilation and MODS are unclear. Our goal was to determine whether a minimally injurious mechanical ventilation strat...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5050
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Respiratory viruses are increasingly recognized as significant etiologies of pneumonia among hospitalized patients. Advanced technologies using multiplex molecular assays and polymerase-chain reaction increase the ability to identify viral pathogens and may ultimately impact antibacterial use. METHOD:This...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-015-1120-5
更新日期:2015-11-18 00:00:00
abstract:BACKGROUND:Atrial fibrillation occurs frequently in patients following cardiac surgery and can be a cause of increased morbidity and mortality. The use of dexmedetomidine to prevent atrial fibrillation is unclear. The present study was designed to evaluate the effect of dexmedetomidine sedation on the incidence of atri...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-016-1480-5
更新日期:2016-09-21 00:00:00
abstract:INTRODUCTION:The main objective was to determine risk factors for presence of multidrug resistant bacteria (MDR) in postoperative peritonitis (PP) and optimal empirical antibiotic therapy (EA) among options proposed by Infectious Disease Society of America and the Surgical Infection Society guidelines. METHODS:One hun...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc8877
更新日期:2010-01-01 00:00:00
abstract::Heart rate variability in the frequency domain can now be obtained at the bedside in the ICU. Promising data suggest that it may help to characterize a patient response to a spontaneous breathing trial. Refinement of the analysis could even help to predict the outcome of extubation or at least help to detect early pat...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc13807
更新日期:2014-03-31 00:00:00
abstract::Venovenous extracorporeal membrane oxygenation (vv-ECMO) has been classically employed as a rescue therapy for patients with respiratory failure not treatable with conventional mechanical ventilation alone. In recent years, however, the timing of ECMO initiation has been readdressed and ECMO is often started earlier i...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-016-1329-y
更新日期:2016-06-30 00:00:00
abstract::Stridor is one of the most frequent causes of early extubation failure. The cuff-leak test may help to identify patients at risk to develop post-extubation laryngeal edema. However the discrimination power of the cuff-leak test is highly variable and can be use, at best, to detect patients at risk to develop edema but...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc3031
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:For patients who survive a critical illness and have their oral endotracheal tube removed, dysphagia is highly prevalent, and without intervention, it may persist far beyond hospital discharge. This pre- and post-intervention study with historical controls tested the effects of a swallowing and oral care (SO...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-019-2623-2
更新日期:2019-11-09 00:00:00
abstract:INTRODUCTION:Sepsis is characterized by systemic microvascular dysfunction. Endothelial progenitor cells (EPCs) are critically involved in maintaining vascular homeostasis under both physiological and pathological conditions. The aim of the present study was to analyze the endothelial progenitor cell system in patients...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10100
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The shock index (SI), defined as heart rate (HR) divided by systolic blood pressure (SBP), is reported to be a more sensitive marker of shock than traditional vital signs alone. In previous literature, use of the reverse shock index (rSI), taken as SBP divided by HR, is recommended instead of SI for hospital...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/s13054-018-2014-0
更新日期:2018-04-11 00:00:00
abstract:INTRODUCTION:The overall prognosis of critically ill patients with cancer has improved during the past decade. The aim of this study was to identify early prognostic factors of intensive care unit (ICU) mortality in patients with cancer. METHODS:We designed a prospective, consecutive, observational study over a one-ye...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5721
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Epidemiological studies have provided inconsistent results on whether intensive care unit (ICU) discharge at night and on weekends is associated with an increased risk of mortality. This systematic review and meta-analysis aimed to determine whether ICU discharge time was associated with hospital mortality. ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s13054-016-1569-x
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Oliguria is one of the leading triggers of fluid loading in patients in the intensive care unit (ICU). The purpose of this study was to assess the predictive value of urine Na(+) (uNa(+)) and other routine urine biomarkers for cardiac fluid responsiveness in oliguric ICU patients. METHODS:We conducted a pro...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/s13054-016-1343-0
更新日期:2016-05-29 00:00:00
abstract:INTRODUCTION:Intensive insulin treatment of critically ill patients was seen as a promising method of treatment, though recent studies showed that reducing the blood glucose level below 6 mmol/l had a detrimental outcome. The mechanisms of the effects of insulin in the critically ill are not completely understood. The ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,随机对照试验
doi:10.1186/cc8202
更新日期:2009-01-01 00:00:00
abstract::There is a paradigm shift happening for sepsis. Sepsis is no longer solely conceptualized as problem of individual patients treated in emergency departments and intensive care units but also as one that is addressed as public health issue with population- and systems-based solutions. We offer a conceptual framework fo...
journal_title:Critical care (London, England)
pub_type: 信件
doi:10.1186/s13054-018-2048-3
更新日期:2018-05-06 00:00:00
abstract::Organ donation offers opportunities for people in critical care units to help save the lives of other patients. It is not always easy, however, to handle the transition from treating a patient to preserving a potential donor, and organ donation consistently provokes ethical questions in critical care units. What do we...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc9379
更新日期:2011-01-24 00:00:00
abstract:INTRODUCTION:Expanding the criteria for deceased organ donors increases the risk of delayed graft function (DGF) and complicates kidney transplant outcome. We studied whether donor neutrophil gelatinase-associated lipocalin (NGAL), a novel biomarker for acute kidney injury, could predict DGF after transplantation. MET...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10220
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Curricular content is often based on the personal opinions of a small number of individuals. Although convenient, such curricula may not meet the needs of the target learner, the program or the institution. Using an objective method to ensure content validity of a curriculum can alleviate this issue. METH...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc7087
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Extracorporeal lung assist, an extreme resource in patients with acute respiratory failure (ARF), is expanding its indications since knowledge about ventilator-induced lung injury has increased and protective ventilation has become the standard in ARF. METHODS:A prospective study on seven adult sheep was ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5082
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The incidence of seizures in intensive care units ranges from 3.3% to 34%. It is therefore often necessary to initiate or continue anticonvulsant drugs in this setting. When a new anticonvulsant is initiated, drug factors, such as onset of action and side effects, and patient factors, such as age, renal, and...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-018-2066-1
更新日期:2018-06-07 00:00:00
abstract::Recent interest in transfusion management of trauma patients has heightened expectation in the role of blood component therapy in improving patient outcome. Optimal transfusion support in supplementation with fibrinogen has not been defined by high-quality evidence. Current evidence comes mainly from case series and u...
journal_title:Critical care (London, England)
pub_type: 评论,社论
doi:10.1186/cc10510
更新日期:2011-01-01 00:00:00
abstract::BACKGROUND: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. RESULTS: A portable, battery-powered blood analyzer was used on patients in life threatening conditions to determine pH, pCO2, pO2, sodium, potassium and ionized c...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc108
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:Recent evidence suggests a link between excess lipid peroxidation and specific organ failures in sepsis. No study has been performed in sepsis by multidrug-resistant (MDR) Gram-negative bacteria. METHODS:Lethal sepsis was induced in rats by the intraperitoneal injection of one MDR isolate of Pseudomonas a...
journal_title:Critical care (London, England)
pub_type: 杂志文章,随机对照试验
doi:10.1186/cc11930
更新日期:2013-01-16 00:00:00
abstract:BACKGROUND:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1855-2
更新日期:2017-10-26 00:00:00