Reverse shock index multiplied by Glasgow Coma Scale score (rSIG) is a simple measure with high discriminant ability for mortality risk in trauma patients: an analysis of the Japan Trauma Data Bank.

Abstract:

BACKGROUND:The shock index (SI), defined as heart rate (HR) divided by systolic blood pressure (SBP), is reported to be a more sensitive marker of shock than traditional vital signs alone. In previous literature, use of the reverse shock index (rSI), taken as SBP divided by HR, is recommended instead of SI for hospital triage. Among traumatized patients aged > 55 years, SI multiplied by age (SIA) might provide better prediction of early post-injury mortality. Separately, the Glasgow Coma Scale (GCS) score has been shown to be a very strong predictor. When considering these points together, rSI multiplied by GCS score (rSIG) or rSIG divided by age (rSIG/A) could provide even better prediction of in-hospital mortality. METHODS:This retrospective, multicenter study used data from 168,517 patients registered in the Japan Trauma Data Bank for the period 2006-2015. We calculated areas under receiver operating characteristic curves (AUROCs) to measure the discriminant ability by comparing those of SI (or rSI), SIA, rSIG, and rSIG/A for in-hospital mortality and for 24-h blood transfusion. RESULTS:The highest ROC AUC (AUROC), 0.901(0.894-0.908) for in-hospital mortality in younger patients (aged < 55 years), was seen for rSIG. In older patients (aged ≥ 55 years), the AUROC of rSIG/A, 0.845(0.840-0.850), was highest for in-hospital mortality. However, the difference between rSIG and rSIG/A was slight and did not seem to be clinically important. rSIG also had the highest AUROC of 0.745 (0.741-749) for 24-h blood transfusion. CONCLUSIONS:rSIG ((SBP/HR) × GCS score) is easy to calculate without the need for additional information, charts or equipment, and can be a more reliable triage tool for identifying risk levels in trauma patients.

journal_name

Crit Care

authors

Kimura A,Tanaka N

doi

10.1186/s13054-018-2014-0

subject

Has Abstract

pub_date

2018-04-11 00:00:00

pages

87

issue

1

eissn

1364-8535

issn

1466-609X

pii

10.1186/s13054-018-2014-0

journal_volume

22

pub_type

杂志文章,多中心研究
  • Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the "Co-MED study".

    abstract:BACKGROUND:Hypernatraemia is common in inpatients and is associated with substantial morbidity. Its differential diagnosis is challenging, and delayed treatment may have devastating consequences. The most important hormone for the regulation of water homeostasis is arginine vasopressin, and copeptin, the C-terminal por...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s13054-018-1955-7

    authors: Nigro N,Winzeler B,Suter-Widmer I,Schuetz P,Arici B,Bally M,Refardt J,Betz M,Gashi G,Urwyler SA,Burget L,Blum CA,Bock A,Huber A,Müller B,Christ-Crain M

    更新日期:2018-02-09 00:00:00

  • Prediction of ventilation weaning outcome: children are not little adults.

    abstract::Prediction of ventilation weaning outcome in children is important, as unsuccessful extubation increases both morbidity and mortality. Adult weaning criteria are poor predictors of weaning outcome in children for several possible reasons: the length of mechanical ventilation is generally much shorter, and the weaning ...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章

    doi:10.1186/cc3950

    authors: Schindler MB

    更新日期:2005-01-01 00:00:00

  • In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: the Italian RED Study.

    abstract:INTRODUCTION:Our aim was to evaluate the role of B-type natriuretic peptide (BNP) percentage variations at 24 hours and at discharge compared to its value at admission in order to demonstrate its predictive value for outcomes in patients with acute decompensated heart failure (ADHF). METHODS:This was a multicenter Ita...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究

    doi:10.1186/cc9067

    authors: Di Somma S,Magrini L,Pittoni V,Marino R,Mastrantuono A,Ferri E,Ballarino P,Semplicini A,Bertazzoni G,Carpinteri G,Mulè P,Pazzaglia M,Shah K,Maisel A,Clopton P

    更新日期:2010-01-01 00:00:00

  • The top cited clinical research articles on sepsis: a bibliometric analysis.

    abstract:INTRODUCTION:The objective of this study was to identify and characterize the most highly cited clinical research articles published on sepsis. METHODS:A comprehensive list of citation classics in sepsis was generated by searching the database of Web of Science-Expanded (1970 to present) using keywords 'sepsis' or 'se...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc11401

    authors: Tao T,Zhao X,Lou J,Bo L,Wang F,Li J,Deng X

    更新日期:2012-06-26 00:00:00

  • Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis.

    abstract:INTRODUCTION:A major pathophysiologic mechanism in sepsis is impaired host immunity which results in failure to eradicate invading pathogens and increased susceptibility to secondary infections. Although many immunosuppressive mechanisms exist, increased expression of the inhibitory receptor programmed cell death 1 (PD...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc13176

    authors: Chang K,Svabek C,Vazquez-Guillamet C,Sato B,Rasche D,Wilson S,Robbins P,Ulbrandt N,Suzich J,Green J,Patera AC,Blair W,Krishnan S,Hotchkiss R

    更新日期:2014-01-04 00:00:00

  • Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas.

    abstract::The use of extracorporeal cardiopulmonary resuscitation (ECPR) to restore circulation during cardiac arrest is a time-critical, resource-intensive intervention of unproven efficacy. The current COVID-19 pandemic has brought additional complexity and significant barriers to the ongoing provision and implementation of E...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-020-03172-2

    authors: Worku E,Gill D,Brodie D,Lorusso R,Combes A,Shekar K

    更新日期:2020-07-27 00:00:00

  • Short-term outcomes of cadaveric lung transplantation in ventilator-dependent patients.

    abstract:INTRODUCTION:Survival after cadaveric lung transplantation (LTx) in respiratory failure recipients who were already dependent on ventilation support prior to transplantation is poor, with a relatively high rate of surgical mortality and morbidity. In this study, we sought to describe the short-term outcomes of bilatera...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc7989

    authors: Hsu HH,Chen JS,Ko WJ,Huang SC,Kuo SW,Huang PM,Chi NH,Chang CC,Chen RJ,Lee YC

    更新日期:2009-01-01 00:00:00

  • Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia.

    abstract:BACKGROUND:Improving timeliness of pathogen identification is crucial to allow early adaptation of antibiotic therapy and improve prognosis in patients with pneumonia. We evaluated the relevance of a new syndromic rapid multiplex PCR test (rm-PCR) on respiratory samples to guide empirical antimicrobial therapy in adult...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-020-03114-y

    authors: Monard C,Pehlivan J,Auger G,Alviset S,Tran Dinh A,Duquaire P,Gastli N,d'Humières C,Maamar A,Boibieux A,Baldeyrou M,Loubinoux J,Dauwalder O,Cattoir V,Armand-Lefèvre L,Kernéis S,ADAPT study group.

    更新日期:2020-07-14 00:00:00

  • Dynamic hyperinflation and intrinsic positive end-expiratory pressure in ARDS patients.

    abstract:BACKGROUND:In ARDS patients, changes in respiratory mechanical properties and ventilatory settings can cause incomplete lung deflation at end-expiration. Both can promote dynamic hyperinflation and intrinsic positive end-expiratory pressure (PEEP). The aim of this study was to investigate, in a large population of ARDS...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-019-2611-6

    authors: Coppola S,Caccioppola A,Froio S,Ferrari E,Gotti M,Formenti P,Chiumello D

    更新日期:2019-11-27 00:00:00

  • Intraoperative milrinone versus dobutamine in cardiac surgery patients: a retrospective cohort study on mortality.

    abstract:BACKGROUND:Several choices of inotropic therapy are available and used in relation to cardiac surgery. Comparisons are necessary to select optimal therapy. In Denmark, dobutamine and milrinone are the two inotropic agents most commonly used to treat post-bypass low cardiac output syndrome. This study compares all-cause...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-018-1969-1

    authors: Nielsen DV,Torp-Pedersen C,Skals RK,Gerds TA,Karaliunaite Z,Jakobsen CJ

    更新日期:2018-02-26 00:00:00

  • Use of ultrasound guidance to improve the safety of percutaneous dilatational tracheostomy: a literature review.

    abstract::Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审

    doi:10.1186/s13054-015-0942-5

    authors: Alansari M,Alotair H,Al Aseri Z,Elhoseny MA

    更新日期:2015-05-18 00:00:00

  • Succinylcholine versus rocuronium for rapid sequence intubation in intensive care: a prospective, randomized controlled trial.

    abstract:INTRODUCTION:Succinylcholine and rocuronium are widely used to facilitate rapid sequence induction (RSI) intubation in intensive care. Concerns relate to the side effects of succinylcholine and to slower onset and inferior intubation conditions associated with rocuronium. So far, succinylcholine and rocuronium have not...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/cc10367

    authors: Marsch SC,Steiner L,Bucher E,Pargger H,Schumann M,Aebi T,Hunziker PR,Siegemund M

    更新日期:2011-08-16 00:00:00

  • Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial.

    abstract:BACKGROUND:Severe traumatic brain injury (TBI) has been increasing with greater incidence of injuries from traffic or sporting accidents. Although there are a number of animal models of TBI using progesterone for head injury, the effects of progesterone on neurologic outcome of acute TBI patients remain unclear. The ai...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/cc6887

    authors: Xiao G,Wei J,Yan W,Wang W,Lu Z

    更新日期:2008-01-01 00:00:00

  • Identification and characterisation of the high-risk surgical population in the United Kingdom.

    abstract:INTRODUCTION:Little is known about mortality rates following general surgical procedures in the United Kingdom. Deaths are most common in the 'high-risk' surgical population consisting mainly of older patients, with coexisting medical disease, who undergo major surgery. Only limited data are presently available to desc...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc4928

    authors: Pearse RM,Harrison DA,James P,Watson D,Hinds C,Rhodes A,Grounds RM,Bennett ED

    更新日期:2006-01-01 00:00:00

  • Ventilator-induced lung injury and mechanotransduction: why should we care?

    abstract::Mechanotransduction holds the underlying mechanisms of ventilator-induced lung injury. Research on this subject, however, could be difficult for clinicians, especially when results are controversial. A recent study by Li and co-workers is used as an example, to explain how to critically read literatures related to bas...

    journal_title:Critical care (London, England)

    pub_type: 评论,社论

    doi:10.1186/cc6131

    authors: Liu M

    更新日期:2007-01-01 00:00:00

  • Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury.

    abstract:BACKGROUND:Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI). However, evidence regarding the prognostic effect of the platelet-to-lymphocyte ratio (PLR), a novel systemic inflammation marker, among patients with AKI is scarce. In this study, we investigated the value o...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-017-1821-z

    authors: Zheng CF,Liu WY,Zeng FF,Zheng MH,Shi HY,Zhou Y,Pan JY

    更新日期:2017-09-08 00:00:00

  • Translocation of bacterial NOD2 agonist and its link with inflammation.

    abstract:INTRODUCTION:The gut is often considered as the motor of critical illness through bacterial translocation, which amplifies the inflammatory response and alters the immune status. However, systemic bacterial translocation was rarely proven and endotoxin measurement only reflects translocation of Gram-negative-derived pr...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc7980

    authors: Kim OY,Monsel A,Bertrand M,Cavaillon JM,Coriat P,Adib-Conquy M

    更新日期:2009-01-01 00:00:00

  • Bench-to-bedside review: carbon dioxide.

    abstract::Carbon dioxide is a waste product of aerobic cellular respiration in all aerobic life forms. PaCO2 represents the balance between the carbon dioxide produced and that eliminated. Hypocapnia remains a common - and generally underappreciated - component of many disease states, including early asthma, high-altitude pulmo...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审

    doi:10.1186/cc8926

    authors: Curley G,Laffey JG,Kavanagh BP

    更新日期:2010-01-01 00:00:00

  • Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation.

    abstract::This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审

    doi:10.1186/s13054-017-1639-8

    authors: Tagami T,Yasunaga H,Yokota H

    更新日期:2017-03-21 00:00:00

  • Muscle regeneration after sepsis.

    abstract::Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but m...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-016-1308-3

    authors: Bouglé A,Rocheteau P,Sharshar T,Chrétien F

    更新日期:2016-05-19 00:00:00

  • Carbon dioxide monitoring and evidence-based practice - now you see it, now you don't.

    abstract::Carbon dioxide has been monitored in the body using a variety of technologies with a multitude of applications. The monitoring of this common physiologic variable in medicine is an illustrative example of the different levels of evidence that are required before any new health technology should establish itself in cli...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc2916

    authors: Gattas D,Ayer R,Suntharalingam G,Chapman M

    更新日期:2004-08-01 00:00:00

  • Systemic endotoxin activity correlates with clot formation: an observational study in patients with early systemic inflammation and sepsis.

    abstract:INTRODUCTION:Inflammation and coagulation are closely linked, and both can be triggered by endotoxin. Thrombelastometry and impedance aggregometry are of diagnostic and predictive value in critically ill patients. In this observational study we investigated the correlation of endotoxin activity with thrombelasometric a...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc12892

    authors: Koch A,Meesters MI,Scheller B,Boer C,Zacharowski K

    更新日期:2013-09-11 00:00:00

  • Effects of dopexamine on the intestinal microvascular blood flow and leukocyte activation in a sepsis model in rats.

    abstract:INTRODUCTION:The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats. METHODS:This prospective, randomized, controlled laboratory study was conducted in...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc5011

    authors: Birnbaum J,Klotz E,Spies CD,Lorenz B,Stuebs P,Hein OV,Grundling M,Pavlovic D,Usichenko T,Wendt M,Kox WJ,Lehmann C

    更新日期:2006-01-01 00:00:00

  • Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore.

    abstract:BACKGROUND:Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the HLH-2004 criteria and HScore, both of which have been developed in pediatric or adult non-critically ill patients, respectively. Therefore, we aimed...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-020-02941-3

    authors: Knaak C,Nyvlt P,Schuster FS,Spies C,Heeren P,Schenk T,Balzer F,La Rosée P,Janka G,Brunkhorst FM,Keh D,Lachmann G

    更新日期:2020-05-24 00:00:00

  • Strain echocardiography in septic shock - a comparison with systolic and diastolic function parameters, cardiac biomarkers and outcome.

    abstract:INTRODUCTION:Myocardial dysfunction is a well-known complication in septic shock but its characteristics and frequency remains elusive. Here, we evaluate global longitudinal peak strain (GLPS) of the left ventricle as a diagnostic and prognostic tool in septic shock. METHODS:Fifty adult patients with septic shock admi...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-015-0857-1

    authors: De Geer L,Engvall J,Oscarsson A

    更新日期:2015-03-26 00:00:00

  • A practical approach to goal-directed echocardiography in the critical care setting.

    abstract::Urgent cardiac ultrasound examination in the critical care setting is clinically useful. Application of goal-directed echocardiography in this setting is quite distinct from typical exploratory diagnostic comprehensive echocardiography, because the urgent critical care setting mandates a goal-directed approach. Goal-d...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-014-0681-z

    authors: Walley PE,Walley KR,Goodgame B,Punjabi V,Sirounis D

    更新日期:2014-12-01 00:00:00

  • Bending the cost curve in the United States: the role of comparative effectiveness research.

    abstract::Owing to an increasing focus on the rising cost of medical care in the United States, bending the cost curve has become the central tenet of healthcare reform. The exact definition of this phrase, however, remains elusive. In order to affect change in the cost and quality of healthcare, the importance of comparative e...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章

    doi:10.1186/cc9045

    authors: Ghaferi AA

    更新日期:2010-01-01 00:00:00

  • Association between kidney intracapsular pressure and ultrasound elastography.

    abstract:BACKGROUND:Kidney congestion is a common pathophysiologic pathway of acute kidney injury (AKI) in sepsis and heart failure. There is no noninvasive tool to measure kidney intracapsular pressure (KIP) directly. METHODS:We evaluated the correlation of KIP with kidney elasticity measured by ultrasound surface wave elasto...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-017-1847-2

    authors: Kashani KB,Mao SA,Safadi S,Amiot BP,Glorioso JM,Lieske JC,Nyberg SL,Zhang X

    更新日期:2017-10-19 00:00:00

  • Parenteral diclofenac infusion significantly decreases brain-tissue oxygen tension in patients with poor-grade aneurysmal subarachnoid hemorrhage.

    abstract:INTRODUCTION:Diclofenac, a nonsteroidal antiinflammatory drug, is commonly used as antipyretic therapy in intensive care. The purpose of this study was to investigate the effects of parenteral diclofenac infusion on brain homeostasis, including brain-tissue oxygen tension (PbtO2) and brain metabolism after aneurysmal s...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/cc12714

    authors: Schiefecker AJ,Pfausler B,Beer R,Sohm F,Sabo J,Knauseder V,Fischer M,Dietmann A,Hackl WO,Thomé C,Schmutzhard E,Helbok R

    更新日期:2013-05-12 00:00:00

  • Association between hospital mortality and inspiratory airway pressures in mechanically ventilated patients without acute respiratory distress syndrome: a prospective cohort study.

    abstract:BACKGROUND:Higher inspiratory airway pressures are associated with worse outcomes in mechanically ventilated patients with the acute respiratory distress syndrome (ARDS). This relationship, however, has not been well investigated in patients without ARDS. We hypothesized that higher driving pressures (ΔP) and plateau p...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章

    doi:10.1186/s13054-019-2635-y

    authors: Sahetya SK,Mallow C,Sevransky JE,Martin GS,Girard TD,Brower RG,Checkley W,Society of Critical Care Medicine Discovery Network Critical Illness Outcomes Study Investigators.

    更新日期:2019-11-21 00:00:00