Prehospital point of care testing of blood gases and electrolytes - an evaluation of IRMA.

abstract：:The pathogenesis of sepsis-induced multiple organ failure may crucially depend on the development of mitochondrial dysfunction and consequent cellular energetic failure. According to this hypothesis, interventions aimed at preventing or reversing mitochondrial damage may have major clinical relevance, although the tim...

journal_title：Critical care (London, England)

authors： Protti A,Singer M

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess the volume of gas being poorly ventilated or non-ventilated within the lungs of patients treated with mechanical ventilation and suffering from acute respiratory distress syndrome (ARDS). METHODS:A prospective, descriptive study was performed of 25 sedated and paralysed...

journal_title：Critical care (London, England)

authors： Rylander C,Tylén U,Rossi-Norrlund R,Herrmann P,Quintel M,Bake B

更新日期：2005-04-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) has a substantial mortality rate and annually affects more than 140,000 people in the USA alone. Standard management includes lung protective ventilation but this impairs carbon dioxide clearance and may lead to right heart dysfunction or increased intracranial pressure. Extr...

journal_title：Critical care (London, England)

authors： Cove ME,MacLaren G,Federspiel WJ,Kellum JA

更新日期：2012-09-21 00:00:00

abstract：BACKGROUND:Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the HLH-2004 criteria and HScore, both of which have been developed in pediatric or adult non-critically ill patients, respectively. Therefore, we aimed...

journal_title：Critical care (London, England)

authors： Knaak C,Nyvlt P,Schuster FS,Spies C,Heeren P,Schenk T,Balzer F,La Rosée P,Janka G,Brunkhorst FM,Keh D,Lachmann G

更新日期：2020-05-24 00:00:00

abstract：:The advent of biologic agents has provided a more specific and targeted approach to the treatment of various hematological malignancies and other autoimmune disorders. Such biologic agents have been relatively well tolerated with fewer adverse events reported as compared with many other chemotherapeutic agents. Rituxi...

journal_title：Critical care (London, England)

authors： Kasi PM,Tawbi HA,Oddis CV,Kulkarni HS

更新日期：2012-08-31 00:00:00

abstract：:Sepsis is characterized by a dysregulated immune response to infection leading to life-threatening organ dysfunction. Sepsis-induced liver injury is recognized as a powerful independent predictor of mortality in the intensive care unit. During systemic infections, the liver regulates immune defenses via bacterial clea...

journal_title：Critical care (London, England)

authors： Sun J,Zhang J,Wang X,Ji F,Ronco C,Tian J,Yin Y

更新日期：2020-10-19 00:00:00

abstract：:During the past 50 years, caring for the critically ill has become increasingly complex and the need for an intensivist has become more evident. Management by intensivists has become a quality indicator for many ICUs. Numerous small studies have demonstrated the beneficial effect of intensivists on outcomes in the cri...

journal_title：Critical care (London, England)

authors： Levy MM

更新日期：2013-10-14 00:00:00

abstract：:The burden of chronic obstructive pulmonary disease on intensive care is heavy, but newer modalities of treatment are now available to improve outcomes. Cardiac-based research continues to generate new drugs and tests to better outcome and aid in early diagnosis. And how do various intensive care interventions compare...

journal_title：Critical care (London, England)

authors： Bandarupalli UM,Williams GD

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Angiopoietin-2 (ang-2), an angiogenic peptide released by endothelial cell Weibel-Palade bodies (WPBs), increases endothelial activation and vascular permeability. Ang-2 is raised in severe sepsis but the mechanisms underlying this are not known. Nitric oxide (NO) inhibits WPB exocytosis, and bioavailabili...

journal_title：Critical care (London, England)

authors： Davis JS,Yeo TW,Piera KA,Woodberry T,Celermajer DS,Stephens DP,Anstey NM

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Sepsis is characterized by systemic microvascular dysfunction. Endothelial progenitor cells (EPCs) are critically involved in maintaining vascular homeostasis under both physiological and pathological conditions. The aim of the present study was to analyze the endothelial progenitor cell system in patients...

journal_title：Critical care (London, England)

authors： Patschan SA,Patschan D,Temme J,Korsten P,Wessels JT,Koziolek M,Henze E,Müller GA

更新日期：2011-01-01 00:00:00

abstract：:Sepsis and septic shock are the leading causes of acute renal failure, multiple organ system dysfunction, and death in the intensive care unit. The pathogenesis of sepsis is complex and comprises a mosaic of interconnected pathways. Several attempts to improve patient outcomes by targeting specific components of this ...

journal_title：Critical care (London, England)

authors： Venkataraman R,Subramanian S,Kellum JA

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Correct bedside measurement of intra-abdominal pressure (IAP) is important. The bladder method is considered as the gold standard for indirect IAP measurement, but the instillation volumes reported in the literature vary substantially. The aim of this study was to evaluate the effect of instillation volume...

journal_title：Critical care (London, England)

authors： Malbrain ML,Deeren DH

更新日期：2006-01-01 00:00:00

abstract：:Providing effective analgesia and adequate sedation is a generally accepted goal of intensive care medicine. Due to its rapid, organ independent and predictable metabolism the short acting opioid remifentanil might be particularly useful for analgesia-based sedation in the intensive care unit (ICU). This hypothesis wa...

journal_title：Critical care (London, England)

authors： Kuhlen R,Putensen C

更新日期：2004-02-01 00:00:00

abstract：INTRODUCTION:Identifying patients who need damage control resuscitation (DCR) early after trauma is pivotal for adequate management of their critical condition. Several trauma-scoring systems have been developed to identify such patients, but most of them are not simple enough to be used in prehospital settings in the ...

journal_title：Critical care (London, England)

authors： Tonglet ML,Minon JM,Seidel L,Poplavsky JL,Vergnion M

更新日期：2014-11-26 00:00:00

abstract：:Prone ventilation (PV) is a ventilatory strategy that frequently improves oxygenation and lung mechanics in critical illness, yet does not consistently improve survival. While the exact physiologic mechanisms related to these benefits remain unproven, one major theoretical mechanism relates to reducing the abdominal e...

journal_title：Critical care (London, England)

authors： Kirkpatrick AW,Pelosi P,De Waele JJ,Malbrain ML,Ball CG,Meade MO,Stelfox HT,Laupland KB

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:This prospective study aimed to assess whether use of the subxiphoid acoustic window in transthoracic echocardiography (TTE) can be an accurate alternative in the absence of an apical view to assess hemodynamic parameters. METHODS:This prospective study took place in a teaching hospital medical ICU. Over ...

journal_title：Critical care (London, England)

authors： Maizel J,Salhi A,Tribouilloy C,Massy ZA,Choukroun G,Slama M

更新日期：2013-09-03 00:00:00

abstract：INTRODUCTION:The effect of sepsis on epidermal wound healing has not been previously studied. It was hypothesised that epidermal wound healing is disturbed in severe sepsis. METHODS:Blister wounds were induced in 35 patients with severe sepsis and in 15 healthy controls. The healing of the wounds was followed up by me...

journal_title：Critical care (London, England)

authors： Koskela M,Gäddnäs F,Ala-Kokko TI,Laurila JJ,Saarnio J,Oikarinen A,Koivukangas V

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Following trauma and systemic inflammatory response syndrome (SIRS), the typical response is an elevation of the total complete blood count (CBC) and a reduction of the lymphocyte count. This leukocytosis typically returns to normal within 48 hours. The persistence of a leukocytosis following trauma is ass...

journal_title：Critical care (London, England)

authors： Heffernan DS,Monaghan SF,Thakkar RK,Machan JT,Cioffi WG,Ayala A

更新日期：2012-01-20 00:00:00

abstract：INTRODUCTION:Functional assessment of arterial load by dynamic arterial elastance (Eadyn), defined as the ratio between pulse pressure variation (PPV) and stroke volume variation (SVV), has recently been shown to predict the arterial pressure response to volume expansion (VE) in hypotensive, preload-dependent patients....

journal_title：Critical care (London, England)

authors： García MI,Romero MG,Cano AG,Aya HD,Rhodes A,Grounds RM,Cecconi M

更新日期：2014-11-19 00:00:00

abstract：:Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, i...

journal_title：Critical care (London, England)

authors： Berger D,Takala J

更新日期：2016-06-09 00:00:00

abstract：:The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basic scientists and clinicians to share recent findings. Apart from the large number of free communications, several sessions of the congress were dedicated to state-of-the-art tutorials given by established speakers. The areas...

journal_title：Critical care (London, England)

authors： Preiser JC

更新日期：2001-12-01 00:00:00

abstract：INTRODUCTION:Enteral nutrition (EN) with eicosapentaenoic acid (EPA)/γ-linolenic acid (GLA) is recommended for mechanically ventilated patients with severe lung injury. EPA/GLA has anti-inflammatory benefits, as evidenced by its association with reduction in pulmonary inflammation, improvement in oxygenation and improv...

journal_title：Critical care (London, England)

authors： Pontes-Arruda A,Martins LF,de Lima SM,Isola AM,Toledo D,Rezende E,Maia M,Magnan GB,Investigating Nutritional Therapy with EPA, GLA and Antioxidants Role in Sepsis Treatment (INTERSEPT) Study Group.

更新日期：2011-06-09 00:00:00

abstract：INTRODUCTION:Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis. METHODS:Eleven anesthetized dogs were hemorrhaged to a mean arterial press...

journal_title：Critical care (London, England)

authors： Bruegger D,Kemming GI,Jacob M,Meisner FG,Wojtczyk CJ,Packert KB,Keipert PE,Faithfull NS,Habler OP,Becker BF,Rehm M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Epidemiological studies have provided inconsistent results on whether intensive care unit (ICU) discharge at night and on weekends is associated with an increased risk of mortality. This systematic review and meta-analysis aimed to determine whether ICU discharge time was associated with hospital mortality. ...

journal_title：Critical care (London, England)

authors： Yang S,Wang Z,Liu Z,Wang J,Ma L

更新日期：2016-12-01 00:00:00

abstract：:Carbon dioxide has been monitored in the body using a variety of technologies with a multitude of applications. The monitoring of this common physiologic variable in medicine is an illustrative example of the different levels of evidence that are required before any new health technology should establish itself in cli...

journal_title：Critical care (London, England)

authors： Gattas D,Ayer R,Suntharalingam G,Chapman M

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats. METHODS:This prospective, randomized, controlled laboratory study was conducted in...

journal_title：Critical care (London, England)

authors： Birnbaum J,Klotz E,Spies CD,Lorenz B,Stuebs P,Hein OV,Grundling M,Pavlovic D,Usichenko T,Wendt M,Kox WJ,Lehmann C

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The mortality benefit of whole-body computed tomography (CT) in early trauma management remains controversial and poorly understood. The objective of this study was to assess the impact of whole-body CT compared with selective CT on mortality and management of patients with severe blunt trauma. METHODS:Th...

journal_title：Critical care (London, England)

authors： Yeguiayan JM,Yap A,Freysz M,Garrigue D,Jacquot C,Martin C,Binquet C,Riou B,Bonithon-Kopp C,FIRST Study Group.

更新日期：2012-06-11 00:00:00

abstract：PURPOSE:The histopathology of sepsis-associated acute kidney injury (AKI) in critically ill patients remains an understudied area. Previous studies have identified that acute tubular necrosis (ATN) is not the only driver of sepsis-AKI. The focus of this study was to identify additional candidate processes that may driv...

journal_title：Critical care (London, England)

authors： Aslan A,van den Heuvel MC,Stegeman CA,Popa ER,Leliveld AM,Molema G,Zijlstra JG,Moser J,van Meurs M

更新日期：2018-12-27 00:00:00

abstract：:With imprecise definitions, inexact measurement tools, and flawed study execution, our clinical science often lags behind bedside experience and simply documents what appear to be the apparent faults or validity of ongoing practices. These impressions are later confirmed, modified, or overturned by the results of the ...

journal_title：Critical care (London, England)

authors： Marini JJ,De Backer D,Ince C,Singer M,Van Haren F,Westphal M,Wischmeyer P

更新日期：2017-12-28 00:00:00

abstract：INTRODUCTION:Transthoracic echocardiography (TTE) is a useful tool for minimally invasive hemodynamic monitoring in the ICU. Dynamic indices (such as the inferior vena cava distensibility index (dIVC)) can be used to predict fluid responsiveness in mechanically ventilated patients. Although quantitative use of the dIVC...

journal_title：Critical care (London, England)

authors： Duwat A,Zogheib E,Guinot P,Levy F,Trojette F,Diouf M,Slama M,Dupont H

更新日期：2014-01-14 00:00:00