Antiepileptic drugs in critically ill patients.

abstract：BACKGROUND:Several choices of inotropic therapy are available and used in relation to cardiac surgery. Comparisons are necessary to select optimal therapy. In Denmark, dobutamine and milrinone are the two inotropic agents most commonly used to treat post-bypass low cardiac output syndrome. This study compares all-cause...

journal_title：Critical care (London, England)

authors： Nielsen DV,Torp-Pedersen C,Skals RK,Gerds TA,Karaliunaite Z,Jakobsen CJ

更新日期：2018-02-26 00:00:00

abstract：:Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income countries. Barriers to reducing the global burden of sepsis include difficulty quantifying attributable morbidity and mortality, low awareness, poverty and health inequ...

journal_title：Critical care (London, England)

authors： Rudd KE,Kissoon N,Limmathurotsakul D,Bory S,Mutahunga B,Seymour CW,Angus DC,West TE

更新日期：2018-09-23 00:00:00

abstract：INTRODUCTION:The study was conducted to validate in vivo the Adequacy Calculator, a Microsoft Excel-based program, designed to assess the prescription and delivery of renal replacement therapy in the critical care setting. METHODS:The design was a prospective cohort study, set in two intensive care units of teaching h...

journal_title：Critical care (London, England)

authors： Ricci Z,Salvatori G,Bonello M,Pisitkun T,Bolgan I,D'Amico G,Dan M,Piccinni P,Ronco C

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:Uncalibrated arterial pulse power analysis has been recently introduced for continuous monitoring of cardiac index (CI). The aim of the present study was to compare the accuracy of arterial pulse power analysis with intermittent transpulmonary thermodilution (TPTD) before and after cardiopulmonary bypass (...

journal_title：Critical care (London, England)

authors： Broch O,Renner J,Höcker J,Gruenewald M,Meybohm P,Schöttler J,Steinfath M,Bein B

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:There has been dramatic improvement in survival for patients with HIV/AIDS; however, some studies on patients with HIV/AIDS and serious illness have reported continued low rates of intensive care. The purpose of this study was to examine patterns of care and outcomes for patients with severe sepsis and HIV...

journal_title：Critical care (London, England)

authors： Mrus JM,Braun L,Yi MS,Linde-Zwirble WT,Johnston JA

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Patients with COVID-19 (COVID) may develop acute respiratory distress syndrome with or without sepsis, coagulopathy and visceral damage. While chest CT scans are routinely performed in the initial assessment of patients with severe pulmonary forms, thymus involvement and reactivation have not been investigat...

journal_title：Critical care (London, England)

authors： Cuvelier P,Roux H,Couëdel-Courteille A,Dutrieux J,Naudin C,Charmeteau de Muylder B,Cheynier R,Squara P,Marullo S

更新日期：2021-01-04 00:00:00

abstract：INTRODUCTION:Although activation of A3 adenosine receptors attenuates reperfusion lung injury and associated apoptosis, the signaling pathway that mediates this protection remains unclear. Adenosine agonists activate mitogen-activated protein kinases, and these kinases have been implicated in ischemia/reperfusion injur...

journal_title：Critical care (London, England)

authors： Matot I,Weiniger CF,Zeira E,Galun E,Joshi BV,Jacobson KA

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Tight glucose control therapy (TGC) has been implemented to control hyperglycemia in ICU patients. TGC may also influence serum potassium concentrations. We therefore investigated the influence of TGC on both serum glucose and serum potassium concentrations and associated mortality. METHOD:We performed a ...

journal_title：Critical care (London, England)

authors： Uijtendaal EV,Zwart-van Rijkom JE,de Lange DW,Lalmohamed A,van Solinge WW,Egberts TC

更新日期：2015-06-22 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. METHODS:A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal...

journal_title：Critical care (London, England)

authors： Bassetti M,Giacobbe DR,Vena A,Trucchi C,Ansaldi F,Antonelli M,Adamkova V,Alicino C,Almyroudi MP,Atchade E,Azzini AM,Carannante N,Carnelutti A,Corcione S,Cortegiani A,Dimopoulos G,Dubler S,García-Garmendia JL,Girardis

更新日期：2019-06-14 00:00:00

abstract：INTRODUCTION:Epidemiologic assessment of critically ill people in Intensive Care Units (ICUs) is needed to ensure the health care system can meet current and future needs. However, few such studies have been published. METHODS:Population-based analysis of all adult ICU care in the Canadian province of Manitoba, 1999 t...

journal_title：Critical care (London, England)

authors： Garland A,Olafson K,Ramsey CD,Yogendran M,Fransoo R

更新日期：2013-09-30 00:00:00

abstract：INTRODUCTION:Neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys-C), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic biomarkers of acute kidney injury (AKI). We aimed to determine the diagnostic properties of these biomarkers for detecting AKI in critically ill...

journal_title：Critical care (London, England)

authors： Dai X,Zeng Z,Fu C,Zhang S,Cai Y,Chen Z

更新日期：2015-05-06 00:00:00

abstract：:Burns are a prevalent and burdensome critical care problem. The priorities of specialized facilities focus on stabilizing the patient, preventing infection, and optimizing functional recovery. Research on burns has generated sustained interest over the past few decades, and several important advancements have resulted...

journal_title：Critical care (London, England)

authors： Rowan MP,Cancio LC,Elster EA,Burmeister DM,Rose LF,Natesan S,Chan RK,Christy RJ,Chung KK

更新日期：2015-06-12 00:00:00

abstract：INTRODUCTION:This study aimed to examine the long-term outcome for patients with end-stage renal failure (ESRF) who survived multiple-organ failure. METHODS:We performed a review of databases from the renal medicine service and intensive care units (ICU) of the participating hospitals within Imperial College Healthcar...

journal_title：Critical care (London, England)

authors： Chapman RJ,Templeton M,Ashworth S,Broomhead R,McLean A,Brett SJ

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:New technology using partial carbon dioxide rebreathing has been developed to measure cardiac output. Because rebreathing increases respiratory effort, we investigated whether a newly developed system with 35 s rebreathing causes a lesser increase in respiratory effort under partial ventilatory support tha...

journal_title：Critical care (London, England)

authors： Tachibana K,Imanaka H,Takeuchi M,Nishida T,Takauchi Y,Nishimura M

更新日期：2005-10-05 00:00:00

abstract：BACKGROUND:Expert systems can help alleviate problems related to the shortage of human resources in critical care, offering expert advice in complex situations. Expert systems use contextual information to provide advice to staff. In mechanical ventilation, it is crucial for an expert system to be able to determine the...

journal_title：Critical care (London, England)

authors： Murias G,Montanyà J,Chacón E,Estruga A,Subirà C,Fernández R,Sales B,de Haro C,López-Aguilar J,Lucangelo U,Villar J,Kacmarek RM,Blanch L

更新日期：2016-08-14 00:00:00

abstract：INTRODUCTION:A major pathophysiologic mechanism in sepsis is impaired host immunity which results in failure to eradicate invading pathogens and increased susceptibility to secondary infections. Although many immunosuppressive mechanisms exist, increased expression of the inhibitory receptor programmed cell death 1 (PD...

journal_title：Critical care (London, England)

authors： Chang K,Svabek C,Vazquez-Guillamet C,Sato B,Rasche D,Wilson S,Robbins P,Ulbrandt N,Suzich J,Green J,Patera AC,Blair W,Krishnan S,Hotchkiss R

更新日期：2014-01-04 00:00:00

abstract：INTRODUCTION:Among critically ill patients with acute kidney injury (AKI) needing continuous renal replacement therapy (CRRT), the effect of convective (via continuous venovenous hemofiltration [CVVH]) versus diffusive (via continuous venovenous hemodialysis [CVVHD]) solute clearance on clinical outcomes is unclear. Ou...

journal_title：Critical care (London, England)

authors： Wald R,Friedrich JO,Bagshaw SM,Burns KE,Garg AX,Hladunewich MA,House AA,Lapinsky S,Klein D,Pannu NI,Pope K,Richardson RM,Thorpe K,Adhikari NK

更新日期：2012-10-24 00:00:00

abstract：:Tight glycaemic control has emerged as a major focus in critical care. However, the struggle to repeat, improve and standardize the results of the initial landmark studies is ongoing. The prospective computerized glycaemic control study by Shulman et al. highlights two emerging and often overlooked aspects of intensiv...

journal_title：Critical care (London, England)

authors： Chase JG,Shaw GM

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:This prospective study aimed to assess whether use of the subxiphoid acoustic window in transthoracic echocardiography (TTE) can be an accurate alternative in the absence of an apical view to assess hemodynamic parameters. METHODS:This prospective study took place in a teaching hospital medical ICU. Over ...

journal_title：Critical care (London, England)

authors： Maizel J,Salhi A,Tribouilloy C,Massy ZA,Choukroun G,Slama M

更新日期：2013-09-03 00:00:00

abstract：INTRODUCTION:Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to evaluate a four-region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care unit. METHODS:Fift...

journal_title：Critical care (London, England)

authors： Enghard P,Rademacher S,Nee J,Hasper D,Engert U,Jörres A,Kruse JM

更新日期：2015-02-06 00:00:00

abstract：INTRODUCTION:There is limited information on whether the incidence of acute kidney injury (AKI) in critically ill patients has changed over time and there is controversy on whether its outcome has improved. METHODS:We interrogated the Australian New Zealand Intensive Care Society Adult Patient Database to obtain data ...

journal_title：Critical care (London, England)

authors： Bagshaw SM,George C,Bellomo R,ANZICS Database Management Committee.

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The diagnostic and prognostic value of arterial blood gas analysis (ABGA) parameters in unselected patients presenting with acute dyspnea to the Emergency Department (ED) is largely unknown. METHODS:We performed a post-hoc analysis of two different prospective studies to investigate the diagnostic and pro...

journal_title：Critical care (London, England)

authors： Burri E,Potocki M,Drexler B,Schuetz P,Mebazaa A,Ahlfeld U,Balmelli C,Heinisch C,Noveanu M,Breidthardt T,Schaub N,Reichlin T,Mueller C

更新日期：2011-01-01 00:00:00

abstract：:Carbon dioxide has been monitored in the body using a variety of technologies with a multitude of applications. The monitoring of this common physiologic variable in medicine is an illustrative example of the different levels of evidence that are required before any new health technology should establish itself in cli...

journal_title：Critical care (London, England)

authors： Gattas D,Ayer R,Suntharalingam G,Chapman M

更新日期：2004-08-01 00:00:00

abstract：:Impairment of the protein C pathway plays a central role in the pathogenesis of sepsis. Administration of recombinant human activated protein C (rhAPC) may correct the dysregulated anticoagulant mechanism and prevent propagation of thrombin generation and formation of microvascular thrombosis. Furthermore, it may simu...

journal_title：Critical care (London, England)

authors： Levi M,van der Poll T

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is a frequent complication after cardiac surgery with cardiopulmonary bypass in infants. Renal near-infrared spectroscopy (NIRS) is used to evaluate regional oximetry in a non-invasive continuous real-time fashion, and reflects tissue perfusion. The aim of this study was to evalua...

journal_title：Critical care (London, England)

authors： Ruf B,Bonelli V,Balling G,Hörer J,Nagdyman N,Braun SL,Ewert P,Reiter K

更新日期：2015-01-29 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors of 14-day and 28-day mortality and develop a model for predicting 14-day and 28-day survival probability among adult hospitalized patients with COVID-19. METHODS:In this multicent...

journal_title：Critical care (London, England)

authors： Zhang S,Guo M,Duan L,Wu F,Hu G,Wang Z,Huang Q,Liao T,Xu J,Ma Y,Lv Z,Xiao W,Zhao Z,Tan X,Meng D,Zhang S,Zhou E,Yin Z,Geng W,Wang X,Zhang J,Chen J,Zhang Y,Jin Y

更新日期：2020-07-16 00:00:00

abstract：INTRODUCTION:Although less invasive than pulmonary artery catheters (PACs), arterial pulse pressure analysis techniques for estimating cardiac output (CO) have not been simultaneously compared to PAC bolus thermodilution CO (COtd) or continuous CO (CCO) devices. METHODS:We compared the accuracy, bias and trending abil...

journal_title：Critical care (London, England)

authors： Hadian M,Kim HK,Severyn DA,Pinsky MR

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Mechanical ventilation with even moderate-sized tidal volumes synergistically increases lung injury in sepsis and has been associated with proinflammatory low-molecular-weight hyaluronan production. High-molecular-weight hyaluronan (HMW HA), in contrast, has been found to be anti-inflammatory. We hypothesi...

journal_title：Critical care (London, England)

authors： Liu YY,Lee CH,Dedaj R,Zhao H,Mrabat H,Sheidlin A,Syrkina O,Huang PM,Garg HG,Hales CA,Quinn DA

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:To investigate the effects of G-CSF or GM-CSF therapy in non-neutropenic patients with sepsis. METHODS:A systematic literature search of Medline, Embase and Cochrane Central Register of Controlled Trials was conducted using specific search terms. A manual review of references was also performed. Eligible ...

journal_title：Critical care (London, England)

authors： Bo L,Wang F,Zhu J,Li J,Deng X

更新日期：2011-01-01 00:00:00

abstract：:The attack on the World Trade Center had the potential to overwhelm New York's health services. Sadly, however, the predicted thousands of treatable patients failed to materialize. Horror and sadness has now been replaced by anger, fear, and the determination to be better prepared next time. This determination not onl...

journal_title：Critical care (London, England)

authors： Tamber PS,Vincent JL

更新日期：2001-12-01 00:00:00