The World Trade Center attack. Lessons for all aspects of health care.

abstract：:Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...

journal_title：Critical care (London, England)

authors： Alansari M,Alotair H,Al Aseri Z,Elhoseny MA

更新日期：2015-05-18 00:00:00

abstract：BACKGROUND:Post-cardiac arrest (CA) patients are at risk of secondary ischemic damage in the case of suboptimal brain oxygenation during an ICU stay. We hypothesized that elevated central venous pressures (CVP) would impair cerebral perfusion and oxygenation (venous cerebral congestion). The aim of the present study wa...

journal_title：Critical care (London, England)

authors： Ameloot K,Genbrugge C,Meex I,Eertmans W,Jans F,De Deyne C,Dens J,Mullens W,Ferdinande B,Dupont M

更新日期：2016-05-15 00:00:00

abstract：INTRODUCTION:Dynamic predictors of fluid responsiveness, namely systolic pressure variation, pulse pressure variation, stroke volume variation and pleth variability index have been shown to be useful to identify in advance patients who will respond to a fluid load by a significant increase in stroke volume and cardiac ...

journal_title：Critical care (London, England)

authors： Benes J,Giglio M,Brienza N,Michard F

更新日期：2014-10-28 00:00:00

abstract：INTRODUCTION:In intensive care unit patients we assessed, using bispectral index (BIS) monitoring, whether the addition of magnesium sulphate infusion could decrease the sufentanil infusion required to maintain sedation. PATIENTS AND METHODS:A total of 30 adult patients who were expected to require mechanical ventilat...

journal_title：Critical care (London, England)

authors： Memiş D,Turan A,Karamanlioglu B,Oguzhan N,Pamukçu Z

更新日期：2003-10-01 00:00:00

abstract：INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

journal_title：Critical care (London, England)

authors： Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

更新日期：2011-01-01 00:00:00

abstract：:Sepsis and septic shock are the leading causes of acute renal failure, multiple organ system dysfunction, and death in the intensive care unit. The pathogenesis of sepsis is complex and comprises a mosaic of interconnected pathways. Several attempts to improve patient outcomes by targeting specific components of this ...

journal_title：Critical care (London, England)

authors： Venkataraman R,Subramanian S,Kellum JA

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Coagulation abnormalities are frequent in sepsis. Conventional coagulation assays, however, have several limitations. A surge of interest exists in the use of point-of-care tests to diagnose hypo- and hypercoagulability in sepsis. METHODS:MEDLINE, EMBASE, and the Cochrane Library were searched from 1 Janu...

journal_title：Critical care (London, England)

authors： Müller MC,Meijers JC,Vroom MB,Juffermans NP

更新日期：2014-02-10 00:00:00

abstract：INTRODUCTION:A lack of data exists in the literature evaluating acidemia on admission as a favorable or negative prognostic factor in patients with acute cardiogenic pulmonary edema (ACPE) treated with non-invasive continuous positive airway pressure (CPAP). The objective of the present study was to investigate the imp...

journal_title：Critical care (London, England)

authors： Aliberti S,Piffer F,Brambilla AM,Bignamini AA,Rosti VD,Maraffi T,Monzani V,Cosentini R

更新日期：2010-01-01 00:00:00

abstract：:Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthe...

journal_title：Critical care (London, England)

authors： Calzia E,Dembinski R

更新日期：2013-11-19 00:00:00

abstract：INTRODUCTION:Mechanical ventilators are increasingly used in critical care units. However, they can cause lung injury, including pulmonary edema. Our previous studies indicated that γ-aminobutyric acid (GABA) receptors are involved in alveolar-fluid homeostasis. The present study investigated the role of GABA receptors...

journal_title：Critical care (London, England)

authors： Chintagari NR,Liu L

更新日期：2012-12-12 00:00:00

abstract：INTRODUCTION:It is unknown whether the reported short-term reduction in cardiac arrests associated with the introduction of the medical emergency team (MET) system can be sustained. METHOD:We conducted a prospective, controlled before-and-after examination of the effect of a MET system on the long-term incidence of ca...

journal_title：Critical care (London, England)

authors： Jones D,Bellomo R,Bates S,Warrillow S,Goldsmith D,Hart G,Opdam H,Gutteridge G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS). METHODS:We prospectively included 20 ICU patients with septic shock...

journal_title：Critical care (London, England)

authors： Harrois A,Grillot N,Figueiredo S,Duranteau J

更新日期：2018-06-15 00:00:00

abstract：:The present review introduces the notion of statistical power and the hazard of under-powered studies. The problem of how to calculate an ideal sample size is also discussed within the context of factors that affect power, and specific methods for the calculation of sample size are presented for two common scenarios, ...

journal_title：Critical care (London, England)

authors： Whitley E,Ball J

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Critical illness following head injury is associated with a hypermetabolic state but there are insufficient epidemiological data describing acute nutrition delivery to this group of patients. Furthermore, there is little information describing relationships between nutrition and clinical outcomes in this pop...

journal_title：Critical care (London, England)

authors： Chapple LA,Chapman MJ,Lange K,Deane AM,Heyland DK

更新日期：2016-01-07 00:00:00

abstract：:High-mobility group box 1 (HMGB1) is a DNA-binding protein that also exhibits proinflammatory cytokine-like activity. HMGB1 is passively released by necrotic cells and also is actively secreted by immunostimulated macrophages, dendritic cells, and enterocytes. Although circulating HMGB1 levels are increased relative t...

journal_title：Critical care (London, England)

authors： Fink MP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow ...

journal_title：Critical care (London, England)

authors： Akin S,Dos Reis Miranda D,Caliskan K,Soliman OI,Guven G,Struijs A,van Thiel RJ,Jewbali LS,Lima A,Gommers D,Zijlstra F,Ince C

更新日期：2017-10-26 00:00:00

abstract：:Even more than in previous disasters, Katrina has proven itself to be a testing ground for a plethora of new technologies. Although not all of these technologies did immediately save lives, in this regard a number of them exhibited considerable potential for the future, and hence there is a need to include them in fut...

journal_title：Critical care (London, England)

authors： Leitl E

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Timely administration of appropriate antibiotic therapy has been shown to improve outcome in hospital-acquired pneumonia (HAP). Empirical treatment guidelines tailored to local ecology have been advocated in antibiotic stewardship programs. We compared a local ecology based algorithm (LEBA) to a surveillan...

journal_title：Critical care (London, England)

authors： De Bus L,Saerens L,Gadeyne B,Boelens J,Claeys G,De Waele JJ,Benoit DD,Decruyenaere J,Depuydt PO

更新日期：2014-07-15 00:00:00

abstract：:Venovenous extracorporeal membrane oxygenation (vv-ECMO) has been classically employed as a rescue therapy for patients with respiratory failure not treatable with conventional mechanical ventilation alone. In recent years, however, the timing of ECMO initiation has been readdressed and ECMO is often started earlier i...

journal_title：Critical care (London, England)

authors： Langer T,Santini A,Bottino N,Crotti S,Batchinsky AI,Pesenti A,Gattinoni L

更新日期：2016-06-30 00:00:00

abstract：INTRODUCTION:Myocardial dysfunction is a well-known complication in septic shock but its characteristics and frequency remains elusive. Here, we evaluate global longitudinal peak strain (GLPS) of the left ventricle as a diagnostic and prognostic tool in septic shock. METHODS:Fifty adult patients with septic shock admi...

journal_title：Critical care (London, England)

authors： De Geer L,Engvall J,Oscarsson A

更新日期：2015-03-26 00:00:00

abstract：INTRODUCTION:Pre-hospital triage is a key element in a trauma system that aims to admit patients to the most suitable trauma center, and may decrease intra-hospital mortality. We evaluated the performance of a pre-hospital procedure in a regional trauma system through measurements of the quality of pre-hospital medical...

journal_title：Critical care (London, England)

authors： Bouzat P,Ageron FX,Brun J,Levrat A,Berthet M,Rancurel E,Thouret JM,Thony F,Arvieux C,Payen JF,TRENAU group.

更新日期：2015-03-18 00:00:00

abstract：BACKGROUND:Hyperbilirubinaemia is a common occurrence in patients who are admitted to intensive care units (ICUs) after major surgery, and it is associated with high mortality. We investigated the incidence of hyperbilirubinaemia after two major types of thoracic surgery: open-heart surgery and oesophagectomy. In order...

journal_title：Critical care (London, England)

authors： Hosotsubo KK,Nishimura M,Nishimura S

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The dysregulated host immune response that defines sepsis varies as a function of both the immune status of the host and the distinct nature of the pathogen. The degree to which immunocompromising comorbidities or immunosuppressive medications affect the immune response to infection is poorly understood beca...

journal_title：Critical care (London, England)

authors： Greenberg JA,Hrusch CL,Jaffery MR,David MZ,Daum RS,Hall JB,Kress JP,Sperling AI,Verhoef PA

更新日期：2018-04-25 00:00:00

abstract：INTRODUCTION:Resuscitation with saline is a standard initial response to hypotension or shock of almost any cause. Saline resuscitation is thought to generate an increase in cardiac output through a preload-dependent (increased end-diastolic volume) augmentation of stroke volume. We sought to confirm this to be the mec...

journal_title：Critical care (London, England)

authors： Kumar A,Anel R,Bunnell E,Zanotti S,Habet K,Haery C,Marshall S,Cheang M,Neumann A,Ali A,Kavinsky C,Parrillo JE

更新日期：2004-06-01 00:00:00

abstract：INTRODUCTION:In the past two decades, healthcare adopted industrial strategies for process measurement and control. In the industry model, care is taken to avoid minimal deviations from a standard. In healthcare there is scarce data to support that a similar strategy can lead to better outcomes. Briefly, when complianc...

journal_title：Critical care (London, England)

authors： Amaral AC,Kure L,Jeffs A

更新日期：2012-05-08 00:00:00

abstract：:Prone ventilation (PV) is a ventilatory strategy that frequently improves oxygenation and lung mechanics in critical illness, yet does not consistently improve survival. While the exact physiologic mechanisms related to these benefits remain unproven, one major theoretical mechanism relates to reducing the abdominal e...

journal_title：Critical care (London, England)

authors： Kirkpatrick AW,Pelosi P,De Waele JJ,Malbrain ML,Ball CG,Meade MO,Stelfox HT,Laupland KB

更新日期：2010-01-01 00:00:00

abstract：:Barriers to the use of selective digestive decontamination include concerns about emergence of resistant organisms, over-estimation of current performance in preventing ventilator-associated pneumonia (VAP), alternative methods of preventing VAP, and misunderstanding of mechanisms of action. A definitive cluster-rando...

journal_title：Critical care (London, England)

authors： Bion J

更新日期：2013-12-19 00:00:00

abstract：:Many prior studies have shown that, in critically ill patients, acute kidney injury (AKI) commonly occurs in association with sepsis and its presence portends an increased likelihood of poor outcomes. In contrast, few studies have focused specifically on the influence of AKI on the long-term risk of developing sepsis....

journal_title：Critical care (London, England)

authors： Clark E,Bagshaw SM

更新日期：2014-01-24 00:00:00

abstract：BACKGROUND:Acute-on-chronic liver failure (ACLF) is characterized by the presence of acute decompensation (AD) of cirrhosis, organ failure, and high short-term mortality rates. Hemodynamic dysfunction and activation of endogenous vasoconstrictor systems are thought to contribute to the pathogenesis of ACLF. We explored...

journal_title：Critical care (London, England)

authors： Kerbert AJC,Verspaget HW,Navarro ÀA,Jalan R,Solà E,Benten D,Durand F,Ginès P,van der Reijden JJ,van Hoek B,Coenraad MJ,CANONIC Study Investigators of the EASL-CLIF Consortium.

更新日期：2017-12-21 00:00:00

abstract：:The definition of what constitutes a 'normal' adrenal response to critical illness is unclear. Consequently, published studies have used a variety of biochemical criteria to define 'adrenal insufficiency'. These criteria have been based on the baseline cortisol level or the increment in cortisol following corticotropi...

journal_title：Critical care (London, England)

authors： Marik PE

更新日期：2006-01-01 00:00:00