Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review.

abstract：:An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global pandemic. Both SARS-CoV-2 and SARS-CoV enter host cells via the angiotensin-converting enzyme 2 (ACE2) receptor, which is expressed in various human organ...

journal_title：Critical care (London, England)

authors： Ni W,Yang X,Yang D,Bao J,Li R,Xiao Y,Hou C,Wang H,Liu J,Yang D,Xu Y,Cao Z,Gao Z

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:We sought to determine the effects of alternative resuscitation strategies on microcirculatory perfusion and examine any association between microcirculatory perfusion and mortality in sepsis. METHODS:This was a prospective, formally designed substudy of participants in the Protocolized Care in Early Septic...

journal_title：Critical care (London, England)

authors： Massey MJ,Hou PC,Filbin M,Wang H,Ngo L,Huang DT,Aird WC,Novack V,Trzeciak S,Yealy DM,Kellum JA,Angus DC,Shapiro NI,ProCESS investigators.

更新日期：2018-11-20 00:00:00

abstract：INTRODUCTION:Neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys-C), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic biomarkers of acute kidney injury (AKI). We aimed to determine the diagnostic properties of these biomarkers for detecting AKI in critically ill...

journal_title：Critical care (London, England)

authors： Dai X,Zeng Z,Fu C,Zhang S,Cai Y,Chen Z

更新日期：2015-05-06 00:00:00

abstract：INTRODUCTION:Recent data have suggested that patient admission during intensive care unit (ICU) morning bedside rounds is associated with less favorable outcome. We undertook the present study to explore the association between morning round-time ICU admissions and hospital mortality in a large Canadian health region. ...

journal_title：Critical care (London, England)

authors： de Souza IA,Karvellas CJ,Gibney RT,Bagshaw SM

更新日期：2012-05-03 00:00:00

abstract：:Severe sepsis and septic shock are among the leading causes of mortality in the intensive care unit. Over a decade ago, early goal-directed therapy (EGDT) emerged as a novel approach for reducing sepsis mortality and was incorporated into guidelines published by the international Surviving Sepsis Campaign. In addition...

journal_title：Critical care (London, England)

authors： Gupta RG,Hartigan SM,Kashiouris MG,Sessler CN,Bearman GM

更新日期：2015-08-28 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is a common complication in intensive care unit (ICU) patients and is associated with increased morbidity and mortality. We compared long-term outcome and quality of life (QOL) in ICU patients with AKI treated with renal replacement therapy (RRT) with matched non-AKI-RRT patients....

journal_title：Critical care (London, England)

authors： Oeyen S,De Corte W,Benoit D,Annemans L,Dhondt A,Vanholder R,Decruyenaere J,Hoste E

更新日期：2015-08-06 00:00:00

abstract：INTRODUCTION:Severe hypoglycemia (blood glucose concentration (BG) < 40 mg/dL) is independently associated with an increased risk of mortality in critically ill patients. The association of milder hypoglycemia (BG < 70 mg/dL) with mortality is less clear. METHODS:Prospectively collected data from two observational coh...

journal_title：Critical care (London, England)

authors： Krinsley JS,Schultz MJ,Spronk PE,Harmsen RE,van Braam Houckgeest F,van der Sluijs JP,Mélot C,Preiser JC

更新日期：2011-07-25 00:00:00

abstract：BACKGROUND:The present study was designed to (1) establish current sedation practice in UK critical care to inform evidence synthesis and potential future primary research and (2) to compare practice reported via a survey with actual practice assessed in a point prevalence study (PPS). METHODS:UK adult general critica...

journal_title：Critical care (London, England)

authors： Richards-Belle A,Canter RR,Power GS,Robinson EJ,Reschreiter H,Wunsch H,Harvey SE

更新日期：2016-10-27 00:00:00

abstract：INTRODUCTION:Prophylactic steroid therapy to reduce the occurrence of postextubation laryngeal edema is controversial. Only a limited number of prospective trials involve adults in an intensive care unit. The purpose of this study was to ascertain whether administration of multiple doses of dexamethasone to critically ...

journal_title：Critical care (London, England)

authors： Lee CH,Peng MJ,Wu CL

更新日期：2007-01-01 00:00:00

abstract：:The past 15 years have seen major advances in our understanding of severity assessment in community-acquired pneumonia (CAP). Prognostic tools have been promoted to guide all major management decisions in CAP, including admission to the critical care unit. Several recent studies, including the study by Renaud and coll...

journal_title：Critical care (London, England)

authors： Chalmers JD

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess the volume of gas being poorly ventilated or non-ventilated within the lungs of patients treated with mechanical ventilation and suffering from acute respiratory distress syndrome (ARDS). METHODS:A prospective, descriptive study was performed of 25 sedated and paralysed...

journal_title：Critical care (London, England)

authors： Rylander C,Tylén U,Rossi-Norrlund R,Herrmann P,Quintel M,Bake B

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Economic evaluations of interventions in the hospital setting often rely on the estimated long-term impact on patient survival. Estimates of mortality rates and long-term outcomes among patients discharged alive from the intensive care unit (ICU) are lacking from lower- and middle-income countries. This st...

journal_title：Critical care (London, England)

authors： Luangasanatip N,Hongsuwan M,Lubell Y,Limmathurotsakul D,Teparrukkul P,Chaowarat S,Day NP,Graves N,Cooper BS

更新日期：2013-10-03 00:00:00

abstract：INTRODUCTION:To investigate the effects of G-CSF or GM-CSF therapy in non-neutropenic patients with sepsis. METHODS:A systematic literature search of Medline, Embase and Cochrane Central Register of Controlled Trials was conducted using specific search terms. A manual review of references was also performed. Eligible ...

journal_title：Critical care (London, England)

authors： Bo L,Wang F,Zhu J,Li J,Deng X

更新日期：2011-01-01 00:00:00

abstract：:The rate of oxygen consumption by certain tissues is impaired when mice or rats are injected with lipopolysaccharide. A similar change in the rate of oxygen consumption is observed when Caco-2 human enterocyte-like cells are incubated in vitro with cytomix, a cocktail of cytokines containing tumor necrosis factor, IL-...

journal_title：Critical care (London, England)

authors： Fink MP

更新日期：2002-12-01 00:00:00

abstract：:Impairment of the protein C pathway plays a central role in the pathogenesis of sepsis. Administration of recombinant human activated protein C (rhAPC) may correct the dysregulated anticoagulant mechanism and prevent propagation of thrombin generation and formation of microvascular thrombosis. Furthermore, it may simu...

journal_title：Critical care (London, England)

authors： Levi M,van der Poll T

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Deregulated apoptosis and overshooting neutrophil functions contribute to immune and organ dysfunction in sepsis and multiple organ failure (MOF). In the present study, we determined the role of soluble Fas (sFas) in the regulation of posttraumatic neutrophil extrinsic apoptosis and the development of seps...

journal_title：Critical care (London, England)

authors： Paunel-Görgülü A,Flohé S,Scholz M,Windolf J,Lögters T

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Tight glucose control therapy (TGC) has been implemented to control hyperglycemia in ICU patients. TGC may also influence serum potassium concentrations. We therefore investigated the influence of TGC on both serum glucose and serum potassium concentrations and associated mortality. METHOD:We performed a ...

journal_title：Critical care (London, England)

authors： Uijtendaal EV,Zwart-van Rijkom JE,de Lange DW,Lalmohamed A,van Solinge WW,Egberts TC

更新日期：2015-06-22 00:00:00

abstract：INTRODUCTION:Recombinant human activated protein C (rhAPC) is the first drug for which a reduction of mortality in severe sepsis has been demonstrated. However, the mechanism by which this reduction in mortality is achieved is still not clearly defined. The aim of the present study was to evaluate the dynamics of the a...

journal_title：Critical care (London, England)

authors： de Pont AC,Bakhtiari K,Hutten BA,de Jonge E,Vroom MB,Meijers JC,Büller HR,Levi M

更新日期：2005-10-05 00:00:00

abstract：:The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The promise of extracorporeal liver replacement therapy and noninvasive ventilation were other areas of interest. Ethical issues als...

journal_title：Critical care (London, England)

authors： Ball J,Venn R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Coagulation can be visualised using whole blood coagulation analyses such as thromboelastometry and platelet aggregation tests; however, the role of temperature in the analyses is ambiguous. The aim was to examine whether temperature influences the whole blood coagulation tests. METHODS:We included 40 patie...

journal_title：Critical care (London, England)

authors： Jeppesen AN,Kirkegaard H,Ilkjær S,Hvas AM

更新日期：2016-04-30 00:00:00

abstract：INTRODUCTION:Respiratory viruses are increasingly recognized as significant etiologies of pneumonia among hospitalized patients. Advanced technologies using multiplex molecular assays and polymerase-chain reaction increase the ability to identify viral pathogens and may ultimately impact antibacterial use. METHOD:This...

journal_title：Critical care (London, England)

authors： Crotty MP,Meyers S,Hampton N,Bledsoe S,Ritchie DJ,Buller RS,Storch GA,Kollef MH,Micek ST

更新日期：2015-11-18 00:00:00

abstract：BACKGROUND:Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the HLH-2004 criteria and HScore, both of which have been developed in pediatric or adult non-critically ill patients, respectively. Therefore, we aimed...

journal_title：Critical care (London, England)

authors： Knaak C,Nyvlt P,Schuster FS,Spies C,Heeren P,Schenk T,Balzer F,La Rosée P,Janka G,Brunkhorst FM,Keh D,Lachmann G

更新日期：2020-05-24 00:00:00

abstract：:Large numbers of patients who survive critical illness are left with significant new cognitive impairments that are often severe and remain years after hospital discharge. In the previous issue of Critical Care, Guerra and colleagues assessed risk factors for the development of dementia after an intensive care unit (I...

journal_title：Critical care (London, England)

authors： Hopkins RO

更新日期：2013-02-06 00:00:00

abstract：BACKGROUND:Atherosclerotic intracranial arterial stenosis is an important cause of stroke that is increasingly being treated with percutaneous transluminal angioplasty and stenting (PTAS) to prevent recurrent stroke. However, PTAS has not been compared with medical management in a randomized trial. METHODS:Objective: ...

journal_title：Critical care (London, England)

authors： Al Hasan M,Murugan R

更新日期：2012-05-09 00:00:00

abstract：BACKGROUND:Severe traumatic brain injury (TBI) has been increasing with greater incidence of injuries from traffic or sporting accidents. Although there are a number of animal models of TBI using progesterone for head injury, the effects of progesterone on neurologic outcome of acute TBI patients remain unclear. The ai...

journal_title：Critical care (London, England)

authors： Xiao G,Wei J,Yan W,Wang W,Lu Z

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Diabetes mellitus (DM) is one of the most common chronic co-morbid medical conditions in the USA and is frequently present in patients with sepsis. Previous studies reported that people with DM and severe sepsis are less likely to develop acute lung injury (ALI). We sought to determine whether organ dysfun...

journal_title：Critical care (London, England)

authors： Esper AM,Moss M,Martin GS

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to investigate whether common variants across the nuclear factor erythroid 2-like 2 (NFE2L2) gene contribute to the development of the acute respiratory distress syndrome (ARDS) in patients with severe sepsis. NFE2L2 is involved in the response to oxidative stress, and it has ...

journal_title：Critical care (London, England)

authors： Acosta-Herrera M,Pino-Yanes M,Blanco J,Ballesteros JC,Ambrós A,Corrales A,Gandía F,Subirá C,Domínguez D,Baluja A,Añón JM,Adalia R,Pérez-Méndez L,Flores C,Villar J,GRECIA and GEN-SEP networks.

更新日期：2015-06-16 00:00:00

abstract：BACKGROUND:Oliguria is one of the leading triggers of fluid loading in patients in the intensive care unit (ICU). The purpose of this study was to assess the predictive value of urine Na(+) (uNa(+)) and other routine urine biomarkers for cardiac fluid responsiveness in oliguric ICU patients. METHODS:We conducted a pro...

journal_title：Critical care (London, England)

authors： Legrand M,Le Cam B,Perbet S,Roger C,Darmon M,Guerci P,Ferry A,Maurel V,Soussi S,Constantin JM,Gayat E,Lefrant JY,Leone M,support of the AZUREA network.

更新日期：2016-05-29 00:00:00

abstract：BACKGROUND:Despite quick implementation of reperfusion therapies, a few patients with high-risk, acute, massive, pulmonary embolism (PE) remain highly hemodynamically unstable. Others have absolute contraindication to receive reperfusion therapies. Venoarterial-extracorporeal membrane oxygenation (VA-ECMO) might lower ...

journal_title：Critical care (London, England)

authors： Corsi F,Lebreton G,Bréchot N,Hekimian G,Nieszkowska A,Trouillet JL,Luyt CE,Leprince P,Chastre J,Combes A,Schmidt M

更新日期：2017-03-28 00:00:00

abstract：:Controversy exists on the role of hyperoxia in major trauma with brain injury. Hyperoxia on arterial blood gas has been associated with acute lung injury and pulmonary complications, impacting clinical outcome. The hyperoxia could be reflective of the physiological interventions following major systemic trauma. Despit...

journal_title：Critical care (London, England)

authors： Narotam PK

更新日期：2013-10-16 00:00:00