Sizing the lung of mechanically ventilated patients.

abstract：INTRODUCTION:Cardio-renal syndromes are characterized by the impairment of cardiac and renal functions. Plasma and urinary neutrophil gelatinase-associated lipocalin (NGAL), and plasma B-type natriuretic peptide (BNP) are markers of acute kidney injury (AKI) and heart failure (HF), respectively. METHODS:GFR (99mTc-DTP...

journal_title：Critical care (London, England)

authors： Donadio C

更新日期：2014-02-28 00:00:00

abstract：INTRODUCTION:Due to resource limitations, few critical care interventions have been rigorously evaluated with adequately powered randomized clinical trials (RCTs). There is a need to improve the efficiency of RCTs in critical care so that more definitive high quality RCTs can be completed with the available resources. ...

journal_title：Critical care (London, England)

authors： Heyland DK,Muscedere J,Drover J,Jiang X,Day AG,Canadian Critical Care Trials Group.

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Procalcitonin (PCT) and C-reactive protein (CRP) are established markers of infection in the general population. In contrast, several studies reported falsely increased PCT levels in patients receiving T-cell antibodies. We evaluated the validity of these markers in patients scheduled for hemopoietic stem ...

journal_title：Critical care (London, England)

authors： Brodska H,Drabek T,Malickova K,Kazda A,Vitek A,Zima T,Markova M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Lowering of hyperglycemia in the intensive care unit (ICU) is widely practiced. We investigated in which way glucose regulation, defined as mean glucose concentration during admission, is associated with ICU mortality in a medical and a surgical cohort. METHODS:Retrospective database cohort study includin...

journal_title：Critical care (London, England)

authors： Siegelaar SE,Hermanides J,Oudemans-van Straaten HM,van der Voort PH,Bosman RJ,Zandstra DF,DeVries JH

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:It is recognized that administration of insulin with glucose decreases catabolic response in sepsis. The aim of the present study was to compare the effects of two levels of insulinaemia on glucose metabolism and energy expenditure in septic patients and volunteers. METHODS:Glucose uptake, oxidation and s...

journal_title：Critical care (London, England)

authors： Rusavy Z,Sramek V,Lacigova S,Novak I,Tesinsky P,Macdonald IA

更新日期：2004-08-01 00:00:00

abstract：:The diagnosis of patients presenting to the emergency department with acute heart failure (AHF) is challenging due to the similarity of AHF symptoms to other conditions such as chronic obstructive pulmonary disease and pneumonia. Additionally, because AHF is most common in an older population, the presentation of coex...

journal_title：Critical care (London, England)

authors： Peacock WF,Cannon CM,Singer AJ,Hiestand BC

更新日期：2015-11-10 00:00:00

abstract：BACKGROUND:Esophageal pressure (Pes) can provide information to guide mechanical ventilation in acute respiratory failure. However, both relative changes and absolute values of Pes can be affected by inappropriate filling of the esophageal balloon and by the elastance of the esophagus wall. We evaluated the feasibility...

journal_title：Critical care (London, England)

authors： Mojoli F,Iotti GA,Torriglia F,Pozzi M,Volta CA,Bianzina S,Braschi A,Brochard L

更新日期：2016-04-11 00:00:00

abstract：INTRODUCTION:This systematic review looks at the use of noninvasive ventilation (NIV), inclusive of noninvasive positive pressure ventilation (NPPV) and continuous positive pressure ventilation (CPAP), in patients with chest trauma to determine its safety and clinical efficacy in patients with blunt chest trauma who ar...

journal_title：Critical care (London, England)

authors： Duggal A,Perez P,Golan E,Tremblay L,Sinuff T

更新日期：2013-07-22 00:00:00

abstract：BACKGROUND:Sepsis is an important cause of neonatal morbidity and mortality; therefore, the early diagnosis of neonatal sepsis is essential. METHOD:Our aim was to compare the diagnostic accuracy of procalcitonin (PCT), C-reactive protein (CRP), procalcitonin combined with C-reactive protein (PCT + CRP) and presepsin i...

journal_title：Critical care (London, England)

authors： Ruan L,Chen GY,Liu Z,Zhao Y,Xu GY,Li SF,Li CN,Chen LS,Tao Z

更新日期：2018-11-21 00:00:00

abstract：INTRODUCTION:As a result of drug sequestration and increased volume of distribution, the extracorporeal membrane oxygenation (ECMO) procedure might lead to a decrease in drug concentrations during a patient's treatment. The aim of this study was to evaluate sedative, antibiotic and immunosuppressive drug loss in ECMO c...

journal_title：Critical care (London, England)

authors： Lemaitre F,Hasni N,Leprince P,Corvol E,Belhabib G,Fillâtre P,Luyt CE,Leven C,Farinotti R,Fernandez C,Combes A

更新日期：2015-02-12 00:00:00

abstract：:Multiple studies have addressed deep vein thrombosis chemoprophylaxis timing in traumatic brain injuries. However, a precise time for safe and effective chemoprophylaxis is uncertain according to experts. A comprehensive literature review on brain injuries was performed to delineate temporal proportions for 1) spontan...

journal_title：Critical care (London, England)

authors： Abdel-Aziz H,Dunham CM,Malik RJ,Hileman BM

更新日期：2015-03-24 00:00:00

abstract：INTRODUCTION:The present study was conducted to assess the value of serum concentration of lipopolysaccharide-binding protein (LBP) in patients with systemic inflammatory response syndrome (SIRS), sepsis and septic shock with respect to its ability to differentiate between infectious and noninfectious etiologies in SIR...

journal_title：Critical care (London, England)

authors： Prucha M,Herold I,Zazula R,Dubska L,Dostal M,Hildebrand T,Hyanek J

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Mottling around the knee, reflecting a reduced skin blood flow, is predictive of mortality in patients with septic shock. However, the causative pathophysiology of mottling remains unknown. We hypothesized that the cutaneous hypoperfusion observed in the mottled area is related to regional endothelial dysfun...

journal_title：Critical care (London, England)

authors： Bourcier S,Joffre J,Dubée V,Preda G,Baudel JL,Bigé N,Leblanc G,Levy BI,Guidet B,Maury E,Ait-Oufella H

更新日期：2017-06-23 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2020. Further information about the Annual Update in Intensive Care and Emergency Medicine is available ...

journal_title：Critical care (London, England)

authors： Jonkman AH,de Vries HJ,Heunks LMA

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Critical illness following head injury is associated with a hypermetabolic state but there are insufficient epidemiological data describing acute nutrition delivery to this group of patients. Furthermore, there is little information describing relationships between nutrition and clinical outcomes in this pop...

journal_title：Critical care (London, England)

authors： Chapple LA,Chapman MJ,Lange K,Deane AM,Heyland DK

更新日期：2016-01-07 00:00:00

abstract：INTRODUCTION:Sepsis is a serious medical condition that requires rapidly administered, appropriate antibiotic treatment. Conventional methods take three or more days for final pathogen identification and antimicrobial susceptibility testing. We organized a prospective observational multicenter study in three study site...

journal_title：Critical care (London, England)

authors： Yanagihara K,Kitagawa Y,Tomonaga M,Tsukasaki K,Kohno S,Seki M,Sugimoto H,Shimazu T,Tasaki O,Matsushima A,Ikeda Y,Okamoto S,Aikawa N,Hori S,Obara H,Ishizaka A,Hasegawa N,Takeda J,Kamihira S,Sugahara K,Asari S,Mur

更新日期：2010-01-01 00:00:00

abstract：:Characteristic patterns of variation over time, namely rhythms, represent a defining feature of complex systems, one that is synonymous with life. Despite the intrinsic dynamic, interdependent and nonlinear relationships of their parts, complex biological systems exhibit robust systemic stability. Applied to critical ...

journal_title：Critical care (London, England)

authors： Seely AJ,Macklem PT

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The aim of life-support measures in brain-dead donors is to preserve the functional value of their organs. In renal transplantation, serum creatinine level is one of the criteria for graft harvest. The aim of this study was to assess the impact of intensive care on donor renal function through two criteria: ...

journal_title：Critical care (London, England)

authors： Blasco V,Leone M,Bouvenot J,Geissler A,Albanèse J,Martin C

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Prognosis in patients suffering out-of-hospital cardiac arrest is poor. Higher survival rates have been observed only in patients with ventricular fibrillation who were fortunate enough to have basic and advanced life support initiated soon after cardiac arrest. An ability to predict cardiac arrest outcome...

journal_title：Critical care (London, England)

authors： Kolar M,Krizmaric M,Klemen P,Grmec S

更新日期：2008-01-01 00:00:00

abstract：:SARS (severe acute respiratory syndrome) proved an enormous physical and emotional challenge to frontline health care workers throughout the world in late 2002 through to mid 2003. A large percentage of patients (many being health care workers themselves) became critically ill. Unfortunately, clinicians caring for the...

journal_title：Critical care (London, England)

authors： Gomersall CD

更新日期：2004-04-01 00:00:00

abstract：:Considerable progress has been made recently in the understanding of how best to accomplish safe and effective ventilation of patients with acute lung injury. Mechanical and nonmechanical factors contribute to causation of ventilator-associated lung injury. Intervention timing helps determine the therapeutic efficacy ...

journal_title：Critical care (London, England)

authors： Marini JJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Calcium release-activated calcium (CRAC) channel inhibitors stabilize the pulmonary endothelium and block proinflammatory cytokine release, potentially mitigating respiratory complications observed in patients with COVID-19. This study aimed to investigate the safety and efficacy of Auxora, a novel, intraven...

journal_title：Critical care (London, England)

authors： Miller J,Bruen C,Schnaus M,Zhang J,Ali S,Lind A,Stoecker Z,Stauderman K,Hebbar S

更新日期：2020-08-14 00:00:00

abstract：INTRODUCTION:A paucity of literature exists regarding delays in transfer out of the intensive care unit. We sought to analyze the incidence, causes, and costs of delayed transfer from a surgical intensive care unit (SICU). METHODS:An IRB-approved prospective observational study was conducted from January 24, 2010, to ...

journal_title：Critical care (London, England)

authors： Johnson DW,Schmidt UH,Bittner EA,Christensen B,Levi R,Pino RM

更新日期：2013-07-04 00:00:00

abstract：:The pathogenesis of septic acute kidney injury (AKI) is not well understood. In the present issue of Critical Care, the combined clinical and experimental study from Mariano's group provides new insight into the disease. The study shows that plasma from septic burn patients with acute renal failure initiated pro-apopt...

journal_title：Critical care (London, England)

authors： Oudemans-van Straaten HM

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Despite experimental evidence, clinical demonstration of acute state of oxidative stress and inflammation during post-cardiac arrest syndrome is lacking. Plasma level of thioredoxin (TRX), a redox-active protein induced under conditions of oxidative stress and inflammation, is increased in various critical...

journal_title：Critical care (London, England)

authors： Mongardon N,Lemiale V,Borderie D,Burke-Gaffney A,Perbet S,Marin N,Charpentier J,Pène F,Chiche JD,Mira JP,Cariou A

更新日期：2013-01-29 00:00:00

abstract：INTRODUCTION:Prompt diagnosis of candidaemia and invasive candidosis is crucial to the early initiation of antifungal therapy. The poor sensitivity of blood cultures (BCs) has led to the development of fungal glycan tests as a diagnostic adjunct. We analysed the performance of tests for the detection of circulating β-D...

journal_title：Critical care (London, England)

authors： Poissy J,Sendid B,Damiens S,Ichi Ishibashi K,François N,Kauv M,Favory R,Mathieu D,Poulain D

更新日期：2014-06-29 00:00:00

abstract：INTRODUCTION:Between 1 and 31% of patients suffering out-of-hospital cardiac arrest (OHCA) survive to discharge from hospital. International studies have shown that the level of care provided by the admitting hospital determines survival for patients suffering from OHCA. These data may only be partially transferable to...

journal_title：Critical care (London, England)

authors： Wnent J,Seewald S,Heringlake M,Lemke H,Brauer K,Lefering R,Fischer M,Jantzen T,Bein B,Messelken M,Gräsner JT

更新日期：2012-09-12 00:00:00

abstract：:Despite progress in the diagnosis, prevention and therapy for hospital-acquired infections, ventilator-associated pneumonia (VAP) continues to complicate the course of a significant proportion of patients receiving mechanical ventilation. Mortality rates among patients with VAP have been reported to be as high as 72%,...

journal_title：Critical care (London, England)

authors： Rello J

更新日期：2005-06-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) is a technique for providing life support, in case the natural lungs are failing and are not able to maintain a sufficient oxygenation of the body's organ systems. ECMO technique was an adaptation of conventional cardiopulmonary bypass techniques and introduced into treatment...

journal_title：Critical care (London, England)

authors： Lewandowski K

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to evaluate a four-region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care unit. METHODS:Fift...

journal_title：Critical care (London, England)

authors： Enghard P,Rademacher S,Nee J,Hasper D,Engert U,Jörres A,Kruse JM

更新日期：2015-02-06 00:00:00