Comparison of sufentanil with sufentanil plus magnesium sulphate for sedation in the intensive care unit using bispectral index.

abstract：:In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest...

journal_title：Critical care (London, England)

authors： Walker PF,Buehner MF,Wood LA,Boyer NL,Driscoll IR,Lundy JB,Cancio LC,Chung KK

更新日期：2015-10-28 00:00:00

abstract：INTRODUCTION:Sepsis, severe sepsis and septic shock are common conditions with high mortality. Their early diagnosis in the Emergency Department (ED) is one of the keys to improving survival. Procalcitonin (PCT) has been used as a biomarker in septic patients but has limited specificity and can be elevated in other sce...

journal_title：Critical care (London, England)

authors： Ulla M,Pizzolato E,Lucchiari M,Loiacono M,Soardo F,Forno D,Morello F,Lupia E,Moiraghi C,Mengozzi G,Battista S

更新日期：2013-07-30 00:00:00

abstract：INTRODUCTION:Ventilator-associated pneumonia (VAP) remains a common hazardous complication in mechanically ventilated patients and is associated with increased morbidity and mortality. We undertook a systematic review and meta-analysis of randomized controlled trials to assess the effect of toothbrushing as a component...

journal_title：Critical care (London, England)

authors： Gu WJ,Gong YZ,Pan L,Ni YX,Liu JC

更新日期：2012-10-12 00:00:00

abstract：INTRODUCTION:The gut is often considered as the motor of critical illness through bacterial translocation, which amplifies the inflammatory response and alters the immune status. However, systemic bacterial translocation was rarely proven and endotoxin measurement only reflects translocation of Gram-negative-derived pr...

journal_title：Critical care (London, England)

authors： Kim OY,Monsel A,Bertrand M,Cavaillon JM,Coriat P,Adib-Conquy M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Circulatory failure during brain death organ donor resuscitation is a problem that compromises recovery of organs. Combined administration of steroid, thyroxine and vasopressin has been proposed to optimize the management of brain deceased donors before recovery of organs. However the single administration...

journal_title：Critical care (London, England)

authors： Pinsard M,Ragot S,Mertes PM,Bleichner JP,Zitouni S,Cook F,Pierrot M,Dube L,Menguy E,Lefèvre LM,Escaravage L,Dequin PF,Vignon P,Pichon N

更新日期：2014-07-23 00:00:00

abstract：:The multicenter study conducted by Lorente and coworkers published in the previous issue of Critical Care demonstrates that matrix metalloproteinase (MMP)-9 and MMP-10 and their inhibitor tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) are promising novel biomarkers to predict severity and outcome of sepsis. I...

journal_title：Critical care (London, England)

authors： Hoffmann U,Brueckmann M,Borggrefe M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Correct bedside measurement of intra-abdominal pressure (IAP) is important. The bladder method is considered as the gold standard for indirect IAP measurement, but the instillation volumes reported in the literature vary substantially. The aim of this study was to evaluate the effect of instillation volume...

journal_title：Critical care (London, England)

authors： Malbrain ML,Deeren DH

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Critical illness is commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycaemia, but not all severely ill develop hyperglycemia and some do even in mild disease. We hypothesised that acute disease only ...

journal_title：Critical care (London, England)

authors： Gornik I,Vujaklija-Brajkovic A,Renar IP,Gasparovic V

更新日期：2010-01-01 00:00:00

abstract：:Venovenous extracorporeal membrane oxygenation (vv-ECMO) has been classically employed as a rescue therapy for patients with respiratory failure not treatable with conventional mechanical ventilation alone. In recent years, however, the timing of ECMO initiation has been readdressed and ECMO is often started earlier i...

journal_title：Critical care (London, England)

authors： Langer T,Santini A,Bottino N,Crotti S,Batchinsky AI,Pesenti A,Gattinoni L

更新日期：2016-06-30 00:00:00

abstract：: ...

journal_title：Critical care (London, England)

authors： Cortegiani A,Shafer SL

更新日期：2018-11-14 00:00:00

abstract：INTRODUCTION:Severe hypoglycemia (blood glucose concentration (BG) < 40 mg/dL) is independently associated with an increased risk of mortality in critically ill patients. The association of milder hypoglycemia (BG < 70 mg/dL) with mortality is less clear. METHODS:Prospectively collected data from two observational coh...

journal_title：Critical care (London, England)

authors： Krinsley JS,Schultz MJ,Spronk PE,Harmsen RE,van Braam Houckgeest F,van der Sluijs JP,Mélot C,Preiser JC

更新日期：2011-07-25 00:00:00

abstract：INTRODUCTION:In the past two decades, healthcare adopted industrial strategies for process measurement and control. In the industry model, care is taken to avoid minimal deviations from a standard. In healthcare there is scarce data to support that a similar strategy can lead to better outcomes. Briefly, when complianc...

journal_title：Critical care (London, England)

authors： Amaral AC,Kure L,Jeffs A

更新日期：2012-05-08 00:00:00

abstract：BACKGROUND:Little is known about the development of acute lung injury outside the intensive care unit. We set out to document the following: the association between predefined clinical conditions and the development of acute lung injury by using the American-European consensus definition; the frequency of lung injury d...

journal_title：Critical care (London, England)

authors： Ferguson ND,Frutos-Vivar F,Esteban A,Gordo F,Honrubia T,Peñuelas O,Algora A,García G,Bustos A,Rodríguez I

更新日期：2007-01-01 00:00:00

abstract：:Severe burn injury remains a major burden on patients and healthcare systems. Following severe burns, the injured tissues mount a local inflammatory response aiming to restore homeostasis. With excessive burn load, the immune response becomes disproportionate and patients may develop an overshooting systemic inflammat...

journal_title：Critical care (London, England)

authors： Flierl MA,Stahel PF,Touban BM,Beauchamp KM,Morgan SJ,Smith WR,Ipaktchi KR

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Neutrophil gelatinase-associated lipocalin (NGAL) is a promising novel biomarker that correlates with the severity and outcome of acute kidney injury (AKI). However, its prognostic utility during the late course of AKI, especially in patients that require renal replacement therapy (RRT) remains unknown. Th...

journal_title：Critical care (London, England)

authors： Kümpers P,Hafer C,Lukasz A,Lichtinghagen R,Brand K,Fliser D,Faulhaber-Walter R,Kielstein JT

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function and the association with microcircula...

journal_title：Critical care (London, England)

authors： Dekker NAM,van Leeuwen ALI,van Strien WWJ,Majolée J,Szulcek R,Vonk ABA,Hordijk PL,Boer C,van den Brom CE

更新日期：2019-04-11 00:00:00

abstract：BACKGROUND:Acute kidney injury and hyperchloremia are commonly present in critically ill septic patients. Our study goal was to evaluate the association of hyperchloremia and acute kidney injury in severe sepsis and septic shock patients. METHODS:In this retrospective cohort study in a provincial tertiary care hospita...

journal_title：Critical care (London, England)

authors： Suetrong B,Pisitsak C,Boyd JH,Russell JA,Walley KR

更新日期：2016-10-06 00:00:00

abstract：INTRODUCTION:Delivery of bronchodilators with a metered-dose inhaler (MDI) and a spacer device in mechanically ventilated patients has become a widespread practice. However, except for the short-acting beta2-agonist salbutamol, the duration of action of other bronchodilators, including long-acting beta2-agonists, deliv...

journal_title：Critical care (London, England)

authors： Malliotakis P,Linardakis M,Gavriilidis G,Georgopoulos D

更新日期：2008-01-01 00:00:00

abstract：:Thromboelastography and thromboelastometry represent viscoelastic diagnostic methodologies with promising application to diseases of altered coagulation. Their use in trauma-induced coagulopathy as a means of assessing the real-time status of the patient's functional coagulation profile in addition to its impact on ef...

journal_title：Critical care (London, England)

authors： Bluth MH,Kashuk JL

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:During septic shock, resistance to the haemodynamic effects of catecholamine vasopressors and inotropes is a well-recognised marker of mortality risk. However, the specific cardiovascular or metabolic response elements that are most closely associated with outcome have not been well defined. The objective ...

journal_title：Critical care (London, England)

authors： Kumar A,Schupp E,Bunnell E,Ali A,Milcarek B,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：:Women are generally under-represented in many academic medical settings. Through a brief commentary on this issue, the present article discusses possible explanations for this under-representation as well as potential solutions. Issues examined include women in leadership positions, attrition out of academic medicine,...

journal_title：Critical care (London, England)

authors： Weinacker A,Stapleton RD

更新日期：2013-01-29 00:00:00

abstract：INTRODUCTION:The overall prognosis of critically ill patients with cancer has improved during the past decade. The aim of this study was to identify early prognostic factors of intensive care unit (ICU) mortality in patients with cancer. METHODS:We designed a prospective, consecutive, observational study over a one-ye...

journal_title：Critical care (London, England)

authors： Mokart D,Sannini A,Brun JP,Faucher M,Blaise D,Blache JL,Faucher C

更新日期：2007-01-01 00:00:00

abstract：:Certain noble gases, though inert, exhibit remarkable biological properties. Notably, xenon and argon provide neuroprotection in animal models of central nervous system injury. In the previous issue of Critical Care, Loetscher and colleagues provided further evidence that argon may have therapeutic properties for neur...

journal_title：Critical care (London, England)

authors： Sanders RD,Ma D,Maze M

更新日期：2010-01-01 00:00:00

abstract：:Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income countries. Barriers to reducing the global burden of sepsis include difficulty quantifying attributable morbidity and mortality, low awareness, poverty and health inequ...

journal_title：Critical care (London, England)

authors： Rudd KE,Kissoon N,Limmathurotsakul D,Bory S,Mutahunga B,Seymour CW,Angus DC,West TE

更新日期：2018-09-23 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) affects a large proportion of the critically ill and is associated with worse patient outcomes. Early identification of AKI can lead to earlier initiation of supportive therapy and better management. In this study, we evaluate the impact of computerized AKI decision support tool int...

journal_title：Critical care (London, England)

authors： Bourdeaux C,Ghosh E,Atallah L,Palanisamy K,Patel P,Thomas M,Gould T,Warburton J,Rivers J,Hadfield J

更新日期：2020-11-23 00:00:00

abstract：INTRODUCTION:Diclofenac, a nonsteroidal antiinflammatory drug, is commonly used as antipyretic therapy in intensive care. The purpose of this study was to investigate the effects of parenteral diclofenac infusion on brain homeostasis, including brain-tissue oxygen tension (PbtO2) and brain metabolism after aneurysmal s...

journal_title：Critical care (London, England)

authors： Schiefecker AJ,Pfausler B,Beer R,Sohm F,Sabo J,Knauseder V,Fischer M,Dietmann A,Hackl WO,Thomé C,Schmutzhard E,Helbok R

更新日期：2013-05-12 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine hospital mortality, long-term mortality, and health service utilization among critically ill patients. We also determined whether these outcomes differed according to demographic and clinical characteristics. METHODS:We conducted a retrospective cohort study of adult...

journal_title：Critical care (London, England)

authors： Hill AD,Fowler RA,Pinto R,Herridge MS,Cuthbertson BH,Scales DC

更新日期：2016-03-31 00:00:00

abstract：INTRODUCTION:There is a need for continuous glucose monitoring in critically ill patients. The objective of this trial was to determine the point accuracy and reliability of a device designed for continuous monitoring of interstitial glucose levels in intensive care unit patients. METHODS:We evaluated point accuracy b...

journal_title：Critical care (London, England)

authors： van Hooijdonk RT,Leopold JH,Winters T,Binnekade JM,Juffermans NP,Horn J,Fischer JC,van Dongen-Lases EC,Schultz MJ

更新日期：2015-02-05 00:00:00

abstract：BACKGROUND:Post-resuscitation hemodynamic instability following out-of-hospital cardiac arrest (OHCA) may occur from myocardial dysfunction underlying cardiogenic shock and/or inflammation-mediated distributive shock. Distinguishing the predominant shock subtype with widely available clinical metrics may have prognosti...

journal_title：Critical care (London, England)

authors： Anderson RJ,Jinadasa SP,Hsu L,Ghafouri TB,Tyagi S,Joshua J,Mueller A,Talmor D,Sell RE,Beitler JR

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:It has been hypothesized that hyperoncotic colloids might contribute to acute kidney injury (AKI). However, the validity of this hypothesis remains unclear. METHODS:A meta-analysis was conducted of randomized controlled trials evaluating AKI after infusion of hyperoncotic albumin and hydroxyethyl starch (...

journal_title：Critical care (London, England)

authors： Wiedermann CJ,Dunzendorfer S,Gaioni LU,Zaraca F,Joannidis M

更新日期：2010-01-01 00:00:00