Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients with sepsis-associated acute kidney injury.

abstract：BACKGROUND:The first FDA-approved test to assess risk for acute kidney injury (AKI), [TIMP-2]•[IGFBP7], is clinically available in many parts of the world, including the USA and Europe. We sought to understand how the test is currently being used clinically. METHODS:We invited a group of experts knowledgeable on the u...

journal_title：Critical care (London, England)

authors： Guzzi LM,Bergler T,Binnall B,Engelman DT,Forni L,Germain MJ,Gluck E,Göcze I,Joannidis M,Koyner JL,Reddy VS,Rimmelé T,Ronco C,Textoris J,Zarbock A,Kellum JA

更新日期：2019-06-20 00:00:00

abstract：:Sepsis and septic shock are the leading causes of acute renal failure, multiple organ system dysfunction, and death in the intensive care unit. The pathogenesis of sepsis is complex and comprises a mosaic of interconnected pathways. Several attempts to improve patient outcomes by targeting specific components of this ...

journal_title：Critical care (London, England)

authors： Venkataraman R,Subramanian S,Kellum JA

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Stimulation of beta2-adrenergic receptors (beta2-ARs) inhibits tumor necrosis factor-alpha (TNF-alpha) release in monocytes. In septic shock, endogenous catecholamines induce beta2-AR downregulation, leading to an increased TNF-alpha release. The aims of this study were to analyze the molecular mechanisms ...

journal_title：Critical care (London, England)

authors： Link A,Selejan S,Maack C,Lenz M,Böhm M

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

journal_title：Critical care (London, England)

authors： Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

更新日期：2011-01-01 00:00:00

abstract：:In this month's issue of Critical Care, Determann and colleagues report the results of a randomized controlled trial comparing the effects of mechanical ventilation (MV) with two tidal volumes (6 versus 10 ml/kg predicted body weight) on cytokine levels in lung lavage fluid and plasma as a surrogate for early identifi...

journal_title：Critical care (London, England)

authors： Villar J,Slutsky AS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Temperature management is used with increased frequency as a tool to mitigate neurological injury. Although frequently used, little is known about the optimal cooling methods for inducing and maintaining controlled normo- and hypothermia in the intensive care unit (ICU). In this study we compared the efficac...

journal_title：Critical care (London, England)

authors： Hoedemaekers CW,Ezzahti M,Gerritsen A,van der Hoeven JG

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:In the past two decades, healthcare adopted industrial strategies for process measurement and control. In the industry model, care is taken to avoid minimal deviations from a standard. In healthcare there is scarce data to support that a similar strategy can lead to better outcomes. Briefly, when complianc...

journal_title：Critical care (London, England)

authors： Amaral AC,Kure L,Jeffs A

更新日期：2012-05-08 00:00:00

abstract：:BACKGROUND: The present study was undertaken to examine the feasibility of venous oxygen measurements in the inferior vena cava (IVC) via a catheter through the umbilical vein. This may serve as a proxy for mixed venous oxygenation and the complications of right atrial cannulation can be avoided at the same time. It h...

journal_title：Critical care (London, England)

authors： Plötz FB,van Lingen RA,Bos AP

更新日期：1998-01-01 00:00:00

abstract：:Acute pancreatitis is an inflammatory disease process which may present with clinical manifestations ranging from benign self-limited disease to overwhelming sepsis. The ability to predict outcome would be helpful in developing treatment plans, and possibly in stratifying patients for clinical trials. ...

journal_title：Critical care (London, England)

authors： Rotstein OD

更新日期：2014-10-20 00:00:00

abstract：:BACKGROUND: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. RESULTS: A portable, battery-powered blood analyzer was used on patients in life threatening conditions to determine pH, pCO2, pO2, sodium, potassium and ionized c...

journal_title：Critical care (London, England)

authors： Prause G,Ratzenhofer-Komenda B,Offner A,Lauda P,Voit H,Pojer H

更新日期：1997-01-01 00:00:00

abstract：:Disagreements between the perceptions of nurses and physicians regarding end-of-life (EOL) decisions are frequent. In a survey carried out in 13 Brazilian ICUs, Fumis and Deheinzelin reported that the majority of nurses, physicians and family members are in favor of limiting life-sustaining therapies in terminally ill...

journal_title：Critical care (London, England)

authors： Soares M

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:To systematically review studies evaluating the performance of Sequential Organ Failure Assessment (SOFA)-based models for predicting mortality in patients in the intensive care unit (ICU). METHODS:Medline, EMBASE and other databases were searched for English-language articles with the major objective of ...

journal_title：Critical care (London, England)

authors： Minne L,Abu-Hanna A,de Jonge E

更新日期：2008-01-01 00:00:00

abstract：:BACKGROUND: In recent years, rural hospitals have expanded their scope of specialized services, which has led to the development and staffing of rural intensive care units (ICUs). There is little information about the breadth, quality or outcomes of these services. This is particularly true for specialized ICU service...

journal_title：Critical care (London, England)

authors： Fieselmann JF,Bock MJ,Hendryx MS,Wakefield D,Helms CM,Bentler SE

更新日期：1999-01-01 00:00:00

abstract：:Determine the effectiveness of decontamination, and perform thorough dry or wet decontamination, depending on the circumstances. Always remain cognizant of the fact that, even after decontamination has been completed, contamination may not have been completely eliminated. Perform periodic monitoring to determine wheth...

journal_title：Critical care (London, England)

authors： Okumura S,Okumura T,Ishimatsu S,Miura K,Maekawa H,Naito T

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function and the association with microcircula...

journal_title：Critical care (London, England)

authors： Dekker NAM,van Leeuwen ALI,van Strien WWJ,Majolée J,Szulcek R,Vonk ABA,Hordijk PL,Boer C,van den Brom CE

更新日期：2019-04-11 00:00:00

abstract：BACKGROUND:Calcium release-activated calcium (CRAC) channel inhibitors stabilize the pulmonary endothelium and block proinflammatory cytokine release, potentially mitigating respiratory complications observed in patients with COVID-19. This study aimed to investigate the safety and efficacy of Auxora, a novel, intraven...

journal_title：Critical care (London, England)

authors： Miller J,Bruen C,Schnaus M,Zhang J,Ali S,Lind A,Stoecker Z,Stauderman K,Hebbar S

更新日期：2020-08-14 00:00:00

abstract：INTRODUCTION:Evidence suggests that dying patients' physical and emotional suffering is inadequately treated in intensive care units. Although there are recommendations regarding decisions to forgo life-sustaining therapy, deciding on withdrawal of life support is difficult, and it is also difficult to decide who shoul...

journal_title：Critical care (London, England)

authors： Fumis RR,Deheinzelin D

更新日期：2010-01-01 00:00:00

abstract：:Investigations on the relationship between sepsis, brain dysfunction, and cerebral perfusion are methodologically very difficult to perform. It is important to interpret the results of such studies in view of our limited ability to diagnose and quantify brain dysfunction and to consider our limited understanding of th...

journal_title：Critical care (London, England)

authors： Steiner LA

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Some types of antimicrobial-coated central venous catheters (A-CVC) have been shown to be cost effective in preventing catheter-related bloodstream infection (CR-BSI). However, not all types have been evaluated, and there are concerns over the quality and usefulness of these earlier studies. There is uncer...

journal_title：Critical care (London, England)

authors： Halton KA,Cook DA,Whitby M,Paterson DL,Graves N

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:There are no easily available markers of renal recovery to guide intermittent hemodialysis (IHD) weaning. The aim of this study was to identify markers for IHD weaning in critically ill patients with acute kidney injury (AKI). METHODS:We performed a retrospective single-center cohort study of patients treat...

journal_title：Critical care (London, England)

authors： Aniort J,Ait Hssain A,Pereira B,Coupez E,Pioche PA,Leroy C,Heng AE,Souweine B,Lautrette A

更新日期：2016-02-19 00:00:00

abstract：INTRODUCTION:The aim of the present study was to investigate the relationship between the blood IL-6 level, the blood glucose level, and glucose control in septic patients. METHODS:This retrospective observational study in a general ICU of a university hospital included a total of 153 patients with sepsis, severe seps...

journal_title：Critical care (London, England)

authors： Nakamura M,Oda S,Sadahiro T,Watanabe E,Abe R,Nakada TA,Morita Y,Hirasawa H

更新日期：2012-12-12 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2020. Further information about the Annual Update in Intensive Care and Emergency Medicine is available ...

journal_title：Critical care (London, England)

authors： Bassetti M,Bandera A,Gori A

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:(1,3)-β-D-Glucan has been widely used in clinical practice for the diagnosis of invasive Candida infections. However, such serum biomarker showed potential to guide antimicrobial therapy in order to reduce the duration of empirical antifungal treatment in critically ill septic patients with suspected invasiv...

journal_title：Critical care (London, England)

authors： De Pascale G,Posteraro B,D'Arrigo S,Spinazzola G,Gaspari R,Bello G,Montini LM,Cutuli SL,Grieco DL,Di Gravio V,De Angelis G,Torelli R,De Carolis E,Tumbarello M,Sanguinetti M,Antonelli M

更新日期：2020-09-05 00:00:00

abstract：INTRODUCTION:The appropriate strategy for trauma-induced coagulopathy management is under debate. We report the treatment of major trauma using mainly coagulation factor concentrates. METHODS:This retrospective analysis included trauma patients who received >or= 5 units of red blood cell concentrate within 24 hours. C...

journal_title：Critical care (London, England)

authors： Schöchl H,Nienaber U,Hofer G,Voelckel W,Jambor C,Scharbert G,Kozek-Langenecker S,Solomon C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Accurate prediction of delirium in the intensive care unit (ICU) may facilitate efficient use of early preventive strategies and stratification of ICU patients by delirium risk in clinical research, but the optimal delirium prediction model to use is unclear. We compared the predictive performance and user c...

journal_title：Critical care (London, England)

authors： Wassenaar A,Schoonhoven L,Devlin JW,van Haren FMP,Slooter AJC,Jorens PG,van der Jagt M,Simons KS,Egerod I,Burry LD,Beishuizen A,Matos J,Donders ART,Pickkers P,van den Boogaard M

更新日期：2018-05-05 00:00:00

abstract：INTRODUCTION:Sepsis is the leading cause of acute kidney injury (AKI) in critical patients. The optimal timing of initiating renal replacement therapy (RRT) in septic AKI patients remains controversial. The objective of this study is to determine the impact of early or late initiation of RRT, as defined using the simpl...

journal_title：Critical care (London, England)

authors： Chou YH,Huang TM,Wu VC,Wang CY,Shiao CC,Lai CF,Tsai HB,Chao CT,Young GH,Wang WJ,Kao TW,Lin SL,Han YY,Chou A,Lin TH,Yang YW,Chen YM,Tsai PR,Lin YF,Huang JW,Chiang WC,Chou NK,Ko WJ,Wu KD,Tsai TJ,NSARF Stud

更新日期：2011-01-01 00:00:00

abstract：:There is persuasive evidence, including the present report by Dubin and colleagues, of a dissociation between increases in arterial pressure produced by vasopressor agents and improvement in microvascular perfusion and delivery of vital substrates. Especially in settings of septic shock, the current routine administra...

journal_title：Critical care (London, England)

authors： Weil MH,Tang W

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Continuous renal replacement therapy (CRRT) has been widely used in critically ill acute kidney injury (AKI) patients. Moreover, some centers operate a specialized CRRT team (SCT) composed of physicians and nurses, but few studies have yet determined the superiority of SCT control. METHODS:A total of 334 ...

journal_title：Critical care (London, England)

authors： Oh HJ,Lee MJ,Kim CH,Kim DY,Lee HS,Park JT,Na S,Han SH,Kang SW,Koh SO,Yoo TH

更新日期：2014-08-13 00:00:00

abstract：:The first part of this review addresses the diagnosis and differential diagnosis of the primary vasculitides Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa. Prompt diagnosis and treatment of these conditions ensures an optimal prognosis. The development of assays fo...

journal_title：Critical care (London, England)

authors： Semple D,Keogh J,Forni L,Venn R

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Despite recent interest in measurement of central venous oxygen saturation (ScvO2), there are no published data describing the pattern of ScvO2 changes after major general surgery or any relationship with outcome. METHODS:ScvO2 and other biochemical, physiological and demographic data were prospectively m...

journal_title：Critical care (London, England)

authors： Pearse R,Dawson D,Fawcett J,Rhodes A,Grounds RM,Bennett ED

更新日期：2005-01-01 00:00:00