Carbon dioxide monitoring and evidence-based practice - now you see it, now you don't.

abstract：INTRODUCTION:In critically ill patients, delirium is a serious and frequent disorder that is associated with a prolonged intensive care and hospital stay and an increased morbidity and mortality. Without the use of a delirium screening instrument, delirium is often missed by ICU nurses and physicians. The effects of im...

journal_title：Critical care (London, England)

authors： van den Boogaard M,Pickkers P,van der Hoeven H,Roodbol G,van Achterberg T,Schoonhoven L

更新日期：2009-01-01 00:00:00

abstract：IMPORTANCE:The optimal approach to airway management during in-hospital cardiac arrest is unknown. OBJECTIVE:To describe hospital-level variation in endotracheal intubation during cardiopulmonary resuscitation (CPR) for in-hospital cardiac arrest and the association between hospital use of endotracheal intubation and ...

journal_title：Critical care (London, England)

authors： Bradley SM,Zhou Y,Ramachandran SK,Engoren M,Donnino M,Girotra S

更新日期：2019-05-06 00:00:00

abstract：:Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but m...

journal_title：Critical care (London, England)

authors： Bouglé A,Rocheteau P,Sharshar T,Chrétien F

更新日期：2016-05-19 00:00:00

abstract：:There is a paradigm shift happening for sepsis. Sepsis is no longer solely conceptualized as problem of individual patients treated in emergency departments and intensive care units but also as one that is addressed as public health issue with population- and systems-based solutions. We offer a conceptual framework fo...

journal_title：Critical care (London, England)

authors： Kempker JA,Wang HE,Martin GS

更新日期：2018-05-06 00:00:00

abstract：:In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest...

journal_title：Critical care (London, England)

authors： Walker PF,Buehner MF,Wood LA,Boyer NL,Driscoll IR,Lundy JB,Cancio LC,Chung KK

更新日期：2015-10-28 00:00:00

abstract：:Heart rate variability in the frequency domain can now be obtained at the bedside in the ICU. Promising data suggest that it may help to characterize a patient response to a spontaneous breathing trial. Refinement of the analysis could even help to predict the outcome of extubation or at least help to detect early pat...

journal_title：Critical care (London, England)

authors： Brochard L

更新日期：2014-03-31 00:00:00

abstract：:Cardiogenic shock is a lethal condition. Physicians are searching for hemodynamic markers which could help risk-stratification of patients in this picture. Torgersen and coworkers present an hourly time integral of the cardiac power index and cardiac index drops to predict outcomes in the setting of cardiogenic shock....

journal_title：Critical care (London, England)

authors： Yilmaz MB,Mebazaa A

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats. METHODS:This prospective, randomized, controlled laboratory study was conducted in...

journal_title：Critical care (London, England)

authors： Birnbaum J,Klotz E,Spies CD,Lorenz B,Stuebs P,Hein OV,Grundling M,Pavlovic D,Usichenko T,Wendt M,Kox WJ,Lehmann C

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Correct bedside measurement of intra-abdominal pressure (IAP) is important. The bladder method is considered as the gold standard for indirect IAP measurement, but the instillation volumes reported in the literature vary substantially. The aim of this study was to evaluate the effect of instillation volume...

journal_title：Critical care (London, England)

authors： Malbrain ML,Deeren DH

更新日期：2006-01-01 00:00:00

abstract：:The optimal length of antimicrobial therapy has not been extensively studied for a great majority of infections and, in critically ill patients affected by ventilator-associated pneumonia, is a persisting and unsolved issue confronting clinicians. The integration of biomarkers, clinical judgment, and microbiologic era...

journal_title：Critical care (London, England)

authors： Martin-Loeches I,Torres A

更新日期：2013-01-21 00:00:00

abstract：INTRODUCTION:It is unknown whether the reported short-term reduction in cardiac arrests associated with the introduction of the medical emergency team (MET) system can be sustained. METHOD:We conducted a prospective, controlled before-and-after examination of the effect of a MET system on the long-term incidence of ca...

journal_title：Critical care (London, England)

authors： Jones D,Bellomo R,Bates S,Warrillow S,Goldsmith D,Hart G,Opdam H,Gutteridge G

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:Hemorrhagic shock induced O2 deficit triggers inflammation and multiple organ failure (MOF). Endogenous H2S has been proposed to be involved in MOF since plasma H2S concentration appears to increase in various types of shocks and to predict mortality. We tested the hypothesis that H2S increases during hemo...

journal_title：Critical care (London, England)

authors： Van de Louw A,Haouzi P

更新日期：2012-10-02 00:00:00

abstract：INTRODUCTION:Delayed gastric emptying occurs frequently in critically ill patients and has the potential to adversely affect both the rate, and extent, of nutrient absorption. However, there is limited information about nutrient absorption in the critically ill, and the relationship between gastric emptying (GE) and ab...

journal_title：Critical care (London, England)

authors： Chapman MJ,Fraser RJ,Matthews G,Russo A,Bellon M,Besanko LK,Jones KL,Butler R,Chatterton B,Horowitz M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Some guidelines to prevent ventilator-associated pneumonia (VAP) do not establish a recommendation for the preferential use of either heat and moisture exchangers (HMEs) or heated humidifiers (HHs), while other guidelines clearly advocate the use of HMEs. The aim of this study was to determine the incidenc...

journal_title：Critical care (London, England)

authors： Lorente L,Lecuona M,Jiménez A,Mora ML,Sierra A

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Frailty is a state of vulnerability to poor resolution of homeostasis after a stressor event and is strongly associated with adverse outcomes. Therefore, the assessment of frailty may be an essential part of evaluation in any healthcare encounter that might result in an escalation of care. The purpose of the...

journal_title：Critical care (London, England)

authors： So RKL,Bannard-Smith J,Subbe CP,Jones DA,van Rosmalen J,Lighthall GK,METHOD study investigators.

更新日期：2018-09-22 00:00:00

abstract：INTRODUCTION:The present study was conducted to assess the value of serum concentration of lipopolysaccharide-binding protein (LBP) in patients with systemic inflammatory response syndrome (SIRS), sepsis and septic shock with respect to its ability to differentiate between infectious and noninfectious etiologies in SIR...

journal_title：Critical care (London, England)

authors： Prucha M,Herold I,Zazula R,Dubska L,Dostal M,Hildebrand T,Hyanek J

更新日期：2003-12-01 00:00:00

abstract：INTRODUCTION:Following trauma, patients may suffer an overwhelming pro-inflammatory response and immune paralysis resulting in infection and multiple organ failure (MOF). Various potentially immunomodulative interventions have been tested. The objective of this study is to systematically review the randomized controlle...

journal_title：Critical care (London, England)

authors： Spruijt NE,Visser T,Leenen LP

更新日期：2010-01-01 00:00:00

abstract：:Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, i...

journal_title：Critical care (London, England)

authors： Berger D,Takala J

更新日期：2016-06-09 00:00:00

abstract：INTRODUCTION:This study hypothesised that a reduction of sound during the night using earplugs could be beneficial in the prevention of intensive care delirium. Two research questions were formulated. First, does the use of earplugs during the night reduce the onset of delirium or confusion in the ICU? Second, does the...

journal_title：Critical care (London, England)

authors： Van Rompaey B,Elseviers MM,Van Drom W,Fromont V,Jorens PG

更新日期：2012-05-04 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www...

journal_title：Critical care (London, England)

authors： Tagami T,Yasunaga H,Yokota H

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) is a newly emerging infectious disease and rapidly escalating epidemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of COVID-19 remains to be elucidated. We aimed to clarify correlation of systemic inflammation with disease s...

journal_title：Critical care (London, England)

authors： Zeng Z,Yu H,Chen H,Qi W,Chen L,Chen G,Yan W,Chen T,Ning Q,Han M,Wu D

更新日期：2020-08-27 00:00:00

abstract：INTRODUCTION:Patients after out-of-hospital cardiac arrest (OHCA) benefit from therapeutic hypothermia for 24 hours. The time needed to reach hypothermia (target temperature of 32 degrees C to 34 degrees C) varies widely. In this study, we explore the relation between measures of body composition and the time needed to...

journal_title：Critical care (London, England)

authors： Jimmink JJ,Binnekade JM,Paulus F,Mathus-Vliegen EM,Schultz MJ,Vroom MB

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Abdominal distension is common in critical illness. There is a growing recognition that intra-abdominal hypertension (IAH) may complicate nonsurgical critical illness as well as after abdominal surgery. However, the pathophysiological basis of the injury to the intestinal mucosal barrier and its influence ...

journal_title：Critical care (London, England)

authors： Cheng J,Wei Z,Liu X,Li X,Yuan Z,Zheng J,Chen X,Xiao G,Li X

更新日期：2013-12-09 00:00:00

abstract：:This review presents key publications from the research field of sepsis published in Critical Care and other relevant journals during 2013. The results of these experimental studies and clinical trials are discussed in the context of current scientific and clinical background. The discussion highlights and summarises ...

journal_title：Critical care (London, England)

authors： de Montmollin E,Annane D

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:The aim of life-support measures in brain-dead donors is to preserve the functional value of their organs. In renal transplantation, serum creatinine level is one of the criteria for graft harvest. The aim of this study was to assess the impact of intensive care on donor renal function through two criteria: ...

journal_title：Critical care (London, England)

authors： Blasco V,Leone M,Bouvenot J,Geissler A,Albanèse J,Martin C

更新日期：2007-01-01 00:00:00

abstract：:In a group of postoperative patients, Taniguchi and coworkers compared the effect of a computerized system for weaning against 'manual care'. The computerized system involved automatic adjustments to the level of pressure support to achieve a target respiratory rate. Manual care involved adjustments to the level of pr...

journal_title：Critical care (London, England)

authors： Adigüzel N,Güngör G,Tobin MJ

更新日期：2009-01-01 00:00:00

abstract：:In the previous issue of Critical Care, Ma and colleagues perform a meta-analysis of five randomized, clinical trials of endothelin antagonists in patients with aneurysmal subarachnoid hemorrhage. There are four trials using clazosentan and one trial with TAK-044. These studies show that endothelin plays an important ...

journal_title：Critical care (London, England)

authors： Macdonald RL

更新日期：2012-11-09 00:00:00

abstract：:The pathogenesis of sepsis-induced multiple organ failure may crucially depend on the development of mitochondrial dysfunction and consequent cellular energetic failure. According to this hypothesis, interventions aimed at preventing or reversing mitochondrial damage may have major clinical relevance, although the tim...

journal_title：Critical care (London, England)

authors： Protti A,Singer M

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Delirium occurs in most ventilated patients and is independently associated with more deaths, longer stay, and higher cost. Guidelines recommend monitoring of delirium in all intensive care unit (ICU) patients, though few data exist in non-ventilated patients. The study objective was to determine the relat...

journal_title：Critical care (London, England)

authors： Thomason JW,Shintani A,Peterson JF,Pun BT,Jackson JC,Ely EW

更新日期：2005-08-01 00:00:00

abstract：INTRODUCTION:Tight glucose control therapy (TGC) has been implemented to control hyperglycemia in ICU patients. TGC may also influence serum potassium concentrations. We therefore investigated the influence of TGC on both serum glucose and serum potassium concentrations and associated mortality. METHOD:We performed a ...

journal_title：Critical care (London, England)

authors： Uijtendaal EV,Zwart-van Rijkom JE,de Lange DW,Lalmohamed A,van Solinge WW,Egberts TC

更新日期：2015-06-22 00:00:00