Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent?


:Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, its role in the pathogenesis of intradialytic hypotension may be overestimated.


Crit Care


Berger D,Takala J




Has Abstract


2016-06-09 00:00:00














  • Short-term outcomes of cadaveric lung transplantation in ventilator-dependent patients.

    abstract:INTRODUCTION:Survival after cadaveric lung transplantation (LTx) in respiratory failure recipients who were already dependent on ventilation support prior to transplantation is poor, with a relatively high rate of surgical mortality and morbidity. In this study, we sought to describe the short-term outcomes of bilatera...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Hsu HH,Chen JS,Ko WJ,Huang SC,Kuo SW,Huang PM,Chi NH,Chang CC,Chen RJ,Lee YC

    更新日期:2009-01-01 00:00:00

  • Acute pancreatitis: a possible role for activated protein C?

    abstract::Acute pancreatitis results from a sequence of events that involve the systemic inflammatory response. Activated C has multiple anti-inflammatory activities and may attenuate the degree of pancreatic injury and systemic organ dysfunction when infused early in pancreatitis. ...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Kirschenbaum L,Astiz M

    更新日期:2005-06-01 00:00:00

  • First evidence of a pro-inflammatory response to severe infection with influenza virus H1N1.

    abstract::The great majority of infections caused by the pandemic variant of the influenza virus (nvH1N1) are self-limited, but a small percentage of patients develop severe symptoms requiring hospitalization. Bermejo-Martin and colleagues have presented a pilot study describing the differences in the early immune response for ...

    journal_title:Critical care (London, England)

    pub_type: 评论,信件


    authors: de Castro IF,Guzmán-Fulgencio M,García-Alvarez M,Resino S

    更新日期:2010-01-01 00:00:00

  • Monocyte deactivation in neutropenic acute respiratory distress syndrome patients treated with granulocyte colony-stimulating factor.

    abstract:INTRODUCTION:In severely neutropenic septic acute respiratory distress syndrome (ARDS) patients, macrophages and monocytes are the last potentially remaining innate immune cells. We have previously shown, however, a deactivation of the alveolar macrophage in neutropenic septic ARDS patients. In the present study, we tr...

    journal_title:Critical care (London, England)

    pub_type: 临床试验,杂志文章


    authors: Mokart D,Kipnis E,Guerre-Berthelot P,Vey N,Capo C,Sannini A,Brun JP,Blache JL,Mege JL,Blaise D,Guery BP

    更新日期:2008-01-01 00:00:00

  • Hyperoncotic colloids and acute kidney injury: a meta-analysis of randomized trials.

    abstract:INTRODUCTION:It has been hypothesized that hyperoncotic colloids might contribute to acute kidney injury (AKI). However, the validity of this hypothesis remains unclear. METHODS:A meta-analysis was conducted of randomized controlled trials evaluating AKI after infusion of hyperoncotic albumin and hydroxyethyl starch (...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析


    authors: Wiedermann CJ,Dunzendorfer S,Gaioni LU,Zaraca F,Joannidis M

    更新日期:2010-01-01 00:00:00

  • Eubaric hyperoxia: controversies in the management of acute traumatic brain injury.

    abstract::Controversy exists on the role of hyperoxia in major trauma with brain injury. Hyperoxia on arterial blood gas has been associated with acute lung injury and pulmonary complications, impacting clinical outcome. The hyperoxia could be reflective of the physiological interventions following major systemic trauma. Despit...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Narotam PK

    更新日期:2013-10-16 00:00:00

  • In-vivo validation of a new non-invasive continuous ventricular stroke volume monitoring system in an animal model.

    abstract:INTRODUCTION:Recently, a non-invasive, continuous ventricular stroke volume monitoring system using skin electrodes has been developed. In contrast to impedance-based methods, the new technique (ventricular field recognition) enables measurement of changes in ventricular volume. A prototype using this new method was bu...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Konings MK,Grundeman PF,Goovaerts HG,Roosendaal MR,Hoefer IE,Doevendans PA,Rademakers FE,Buhre WF

    更新日期:2011-07-11 00:00:00

  • Pre-admission functional status impacts the performance of the APACHE IV model of mortality prediction in critically ill patients.

    abstract:BACKGROUND:Functional status (FS) before intensive care unit (ICU) admission is associated with short-term and long-term outcomes among critically ill patients. However, measures of FS are generally not integrated into ICU-specific mortality prediction models. METHODS:This retrospective cohort study used prospectively...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Krinsley JS,Wasser T,Kang G,Bagshaw SM

    更新日期:2017-05-15 00:00:00

  • Immune derangement occurs in patients with H7N9 avian influenza.

    abstract:INTRODUCTION:Currently, little is known about the immunological characteristics of patients with avian influenza A (H7N9) virus infection. METHODS:The numbers and percentages of peripheral blood immune cells were measured in 27 patients with laboratory-confirmed H7N9 virus infection and 30 healthy controls (HCs). The ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Wu W,Shi Y,Gao H,Liang W,Sheng J,Li L

    更新日期:2014-03-24 00:00:00

  • Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial.

    abstract:BACKGROUND:There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen concentrate, which may have advantages of more rapid administrati...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Curry N,Foley C,Wong H,Mora A,Curnow E,Zarankaite A,Hodge R,Hopkins V,Deary A,Ray J,Moss P,Reed MJ,Kellett S,Davenport R,Stanworth S

    更新日期:2018-06-18 00:00:00

  • Protective reactive thymus hyperplasia in COVID-19 acute respiratory distress syndrome.

    abstract:BACKGROUND:Patients with COVID-19 (COVID) may develop acute respiratory distress syndrome with or without sepsis, coagulopathy and visceral damage. While chest CT scans are routinely performed in the initial assessment of patients with severe pulmonary forms, thymus involvement and reactivation have not been investigat...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Cuvelier P,Roux H,Couëdel-Courteille A,Dutrieux J,Naudin C,Charmeteau de Muylder B,Cheynier R,Squara P,Marullo S

    更新日期:2021-01-04 00:00:00

  • Changes in stroke volume induced by passive leg raising in spontaneously breathing patients: comparison between echocardiography and Vigileo/FloTrac device.

    abstract:INTRODUCTION:Passive leg raising (PLR) is a simple reversible maneuver that mimics rapid fluid loading and increases cardiac preload. The effects of this endogenous volume expansion on stroke volume enable the testing of fluid responsiveness with accuracy in spontaneously breathing patients. However, this maneuver requ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Biais M,Vidil L,Sarrabay P,Cottenceau V,Revel P,Sztark F

    更新日期:2009-01-01 00:00:00

  • Transcranial Doppler combined with quantitative EEG brain function monitoring and outcome prediction in patients with severe acute intracerebral hemorrhage.

    abstract:BACKGROUND:Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related to increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) is increasingly used as an indirect measure of ICP, and quantitative EEG (QEEG) can ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Chen Y,Xu W,Wang L,Yin X,Cao J,Deng F,Xing Y,Feng J

    更新日期:2018-02-20 00:00:00

  • Circulating pro-apoptotic mediators in burn septic acute renal failure.

    abstract::The pathogenesis of septic acute kidney injury (AKI) is not well understood. In the present issue of Critical Care, the combined clinical and experimental study from Mariano's group provides new insight into the disease. The study shows that plasma from septic burn patients with acute renal failure initiated pro-apopt...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Oudemans-van Straaten HM

    更新日期:2008-01-01 00:00:00

  • Preserving spontaneous breathing during mechanical ventilatory support: an old yet fascinating story.

    abstract::Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthe...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Calzia E,Dembinski R

    更新日期:2013-11-19 00:00:00

  • Hippocrates is alive and weaning in Brazil.

    abstract::In a group of postoperative patients, Taniguchi and coworkers compared the effect of a computerized system for weaning against 'manual care'. The computerized system involved automatic adjustments to the level of pressure support to achieve a target respiratory rate. Manual care involved adjustments to the level of pr...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Adigüzel N,Güngör G,Tobin MJ

    更新日期:2009-01-01 00:00:00

  • Role of selective V2-receptor-antagonism in septic shock: a randomized, controlled, experimental study.

    abstract:INTRODUCTION:V(2)-receptor (V(2)R) stimulation potentially aggravates sepsis-induced vasodilation, fluid accumulation and microvascular thrombosis. Therefore, the present study was performed to determine the effects of a first-line therapy with the selective V(2)R-antagonist (Propionyl(1)-D-Tyr(Et)(2)-Val(4)-Abu(6)-Arg...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Rehberg S,Ertmer C,Lange M,Morelli A,Whorton E,Dünser M,Strohhäcker AK,Lipke E,Kampmeier TG,Van Aken H,Traber DL,Westphal M

    更新日期:2010-01-01 00:00:00

  • Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study.

    abstract:INTRODUCTION:Anemia is a frequently encountered problem during inflammation. Hepcidin is an interleukin-6 (IL-6)-induced key modulator of inflammation-associated anemia. Human sepsis is a prototypical inflammatory syndrome, often complicated by the development of anemia. However, the association between inflammation, h...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: van Eijk LT,Kroot JJ,Tromp M,van der Hoeven JG,Swinkels DW,Pickkers P

    更新日期:2011-01-01 00:00:00

  • Challenging the rationale of routine vasopressor therapy for management of hypotension.

    abstract::There is persuasive evidence, including the present report by Dubin and colleagues, of a dissociation between increases in arterial pressure produced by vasopressor agents and improvement in microvascular perfusion and delivery of vital substrates. Especially in settings of septic shock, the current routine administra...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Weil MH,Tang W

    更新日期:2009-01-01 00:00:00

  • Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions.

    abstract:INTRODUCTION:Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis. METHODS:Eleven anesthetized dogs were hemorrhaged to a mean arterial press...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Bruegger D,Kemming GI,Jacob M,Meisner FG,Wojtczyk CJ,Packert KB,Keipert PE,Faithfull NS,Habler OP,Becker BF,Rehm M

    更新日期:2007-01-01 00:00:00

  • Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study.

    abstract:BACKGROUND:Effective antimicrobial treatment is key to reduce mortality associated with bacterial sepsis in patients on intensive care units (ICUs). Dose adjustments are often necessary to account for pathophysiological changes or renal replacement therapy. Extracorporeal membrane oxygenation (ECMO) is increasingly bei...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Kühn D,Metz C,Seiler F,Wehrfritz H,Roth S,Alqudrah M,Becker A,Bracht H,Wagenpfeil S,Hoffmann M,Bals R,Hübner U,Geisel J,Lepper PM,Becker SL

    更新日期:2020-11-25 00:00:00

  • Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study.

    abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors of 14-day and 28-day mortality and develop a model for predicting 14-day and 28-day survival probability among adult hospitalized patients with COVID-19. METHODS:In this multicent...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Zhang S,Guo M,Duan L,Wu F,Hu G,Wang Z,Huang Q,Liao T,Xu J,Ma Y,Lv Z,Xiao W,Zhao Z,Tan X,Meng D,Zhang S,Zhou E,Yin Z,Geng W,Wang X,Zhang J,Chen J,Zhang Y,Jin Y

    更新日期:2020-07-16 00:00:00

  • Bench-to-bedside review: Bacterial virulence and subversion of host defences.

    abstract::Bacterial pathogens possess an array of specific mechanisms that confer virulence and the capacity to avoid host defence mechanisms. Mechanisms of virulence are often mediated by the subversion of normal aspects of host biology. In this way the pathogen modifies host function so as to promote the pathogen's survival o...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Webb SA,Kahler CM

    更新日期:2008-01-01 00:00:00

  • Sepsis is a preventable public health problem.

    abstract::There is a paradigm shift happening for sepsis. Sepsis is no longer solely conceptualized as problem of individual patients treated in emergency departments and intensive care units but also as one that is addressed as public health issue with population- and systems-based solutions. We offer a conceptual framework fo...

    journal_title:Critical care (London, England)

    pub_type: 信件


    authors: Kempker JA,Wang HE,Martin GS

    更新日期:2018-05-06 00:00:00

  • Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study.

    abstract:INTRODUCTION:Recombinant human activated protein C (rhAPC) is the first drug for which a reduction of mortality in severe sepsis has been demonstrated. However, the mechanism by which this reduction in mortality is achieved is still not clearly defined. The aim of the present study was to evaluate the dynamics of the a...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: de Pont AC,Bakhtiari K,Hutten BA,de Jonge E,Vroom MB,Meijers JC,Büller HR,Levi M

    更新日期:2005-10-05 00:00:00

  • Transfusion trigger: when to transfuse?

    abstract::The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivi...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Marshall JC

    更新日期:2004-01-01 00:00:00

  • Sizing the lung of mechanically ventilated patients.

    abstract:INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

    更新日期:2011-01-01 00:00:00

  • Prevalence of post-traumatic stress disorder symptoms in adult critical care survivors: a systematic review and meta-analysis.

    abstract:BACKGROUND:As more patients are surviving intensive care, mental health concerns in survivors have become a research priority. Among these, post-traumatic stress disorder (PTSD) can have an important impact on the quality of life of critical care survivors. However, data on its burden are conflicting. Therefore, this s...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析


    authors: Righy C,Rosa RG,da Silva RTA,Kochhann R,Migliavaca CB,Robinson CC,Teche SP,Teixeira C,Bozza FA,Falavigna M

    更新日期:2019-06-11 00:00:00

  • Venous oxygen measurements in the inferior vena cava in neonates with respiratory failure.

    abstract::BACKGROUND: The present study was undertaken to examine the feasibility of venous oxygen measurements in the inferior vena cava (IVC) via a catheter through the umbilical vein. This may serve as a proxy for mixed venous oxygenation and the complications of right atrial cannulation can be avoided at the same time. It h...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Plötz FB,van Lingen RA,Bos AP

    更新日期:1998-01-01 00:00:00

  • Artificial neural networks as prediction tools in the critically ill.

    abstract::The past 25 years have witnessed the development of improved tools with which to predict short-term and long-term outcomes after critical illness. The general paradigm for constructing the best known tools has been the logistic regression model. Recently, a variety of alternative tools, such as artificial neural netwo...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Clermont G

    更新日期:2005-04-01 00:00:00