Is there more to glycaemic control than meets the eye?

abstract：:Base deficit has frequently been utilized as an informal adjunct in the initial evaluation of trauma patients to assess the extent of their physiologic derangements. However, the current Advanced Trauma Life Support (ATLS) classification system for hypovolemic shock does not include base-deficit measurements and relie...

journal_title：Critical care (London, England)

authors： Privette AR,Dicker RA

更新日期：2013-03-13 00:00:00

abstract：:The rate of oxygen consumption by certain tissues is impaired when mice or rats are injected with lipopolysaccharide. A similar change in the rate of oxygen consumption is observed when Caco-2 human enterocyte-like cells are incubated in vitro with cytomix, a cocktail of cytokines containing tumor necrosis factor, IL-...

journal_title：Critical care (London, England)

authors： Fink MP

更新日期：2002-12-01 00:00:00

abstract：INTRODUCTION:Leukocyte infiltration is central to the development of acute lung injury, but it is not known how mechanical ventilation strategy alters the distribution or activation of inflammatory cells. We explored how protective (vs. injurious) ventilation alters the magnitude and distribution of lung leukocyte acti...

journal_title：Critical care (London, England)

authors： de Prost N,Costa EL,Wellman T,Musch G,Tucci MR,Winkler T,Harris R,Venegas JG,Kavanagh BP,Vidal Melo MF

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome coronavirus infection is associated with high mortality rates but limited clinical data have been reported. We describe the clinical features and outcomes of patients admitted to an intensive care unit (ICU) with Middle East respiratory syndrome coronavirus (MERS-CoV) infecti...

journal_title：Critical care (London, England)

authors： Almekhlafi GA,Albarrak MM,Mandourah Y,Hassan S,Alwan A,Abudayah A,Altayyar S,Mustafa M,Aldaghestani T,Alghamedi A,Talag A,Malik MK,Omrani AS,Sakr Y

更新日期：2016-05-07 00:00:00

abstract：INTRODUCTION:Resuscitation with saline is a standard initial response to hypotension or shock of almost any cause. Saline resuscitation is thought to generate an increase in cardiac output through a preload-dependent (increased end-diastolic volume) augmentation of stroke volume. We sought to confirm this to be the mec...

journal_title：Critical care (London, England)

authors： Kumar A,Anel R,Bunnell E,Zanotti S,Habet K,Haery C,Marshall S,Cheang M,Neumann A,Ali A,Kavinsky C,Parrillo JE

更新日期：2004-06-01 00:00:00

abstract：INTRODUCTION:Epidemiologic assessment of critically ill people in Intensive Care Units (ICUs) is needed to ensure the health care system can meet current and future needs. However, few such studies have been published. METHODS:Population-based analysis of all adult ICU care in the Canadian province of Manitoba, 1999 t...

journal_title：Critical care (London, England)

authors： Garland A,Olafson K,Ramsey CD,Yogendran M,Fransoo R

更新日期：2013-09-30 00:00:00

abstract：BACKGROUND:Kidney congestion is a common pathophysiologic pathway of acute kidney injury (AKI) in sepsis and heart failure. There is no noninvasive tool to measure kidney intracapsular pressure (KIP) directly. METHODS:We evaluated the correlation of KIP with kidney elasticity measured by ultrasound surface wave elasto...

journal_title：Critical care (London, England)

authors： Kashani KB,Mao SA,Safadi S,Amiot BP,Glorioso JM,Lieske JC,Nyberg SL,Zhang X

更新日期：2017-10-19 00:00:00

abstract：:Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...

journal_title：Critical care (London, England)

authors： Alansari M,Alotair H,Al Aseri Z,Elhoseny MA

更新日期：2015-05-18 00:00:00

abstract：INTRODUCTION:The purpose of this study was to perform a descriptive, content-based analysis on the different forms of documentation for in-flight medical emergencies that are currently provided in the emergency medical kits on board commercial airlines. METHODS:Passenger airlines in the World Airline Directory were co...

journal_title：Critical care (London, England)

authors： Sand M,Morrosch S,Sand D,Altmeyer P,Bechara FG

更新日期：2012-12-12 00:00:00

abstract：:Great variability exists in data collection and coding of variables in studies on traumatic brain injury (TBI). This confounds comparison of results and analysis of data across studies. The difficulties in performing a meta-analysis of individual patient data were recently illustrated in the IMPACT project (Internatio...

journal_title：Critical care (London, England)

authors： Maas AI

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Myocardial dysfunction is a well-known complication in septic shock but its characteristics and frequency remains elusive. Here, we evaluate global longitudinal peak strain (GLPS) of the left ventricle as a diagnostic and prognostic tool in septic shock. METHODS:Fifty adult patients with septic shock admi...

journal_title：Critical care (London, England)

authors： De Geer L,Engvall J,Oscarsson A

更新日期：2015-03-26 00:00:00

abstract：BACKGROUND:The dysregulated host immune response that defines sepsis varies as a function of both the immune status of the host and the distinct nature of the pathogen. The degree to which immunocompromising comorbidities or immunosuppressive medications affect the immune response to infection is poorly understood beca...

journal_title：Critical care (London, England)

authors： Greenberg JA,Hrusch CL,Jaffery MR,David MZ,Daum RS,Hall JB,Kress JP,Sperling AI,Verhoef PA

更新日期：2018-04-25 00:00:00

abstract：BACKGROUND:The shock index (SI), defined as heart rate (HR) divided by systolic blood pressure (SBP), is reported to be a more sensitive marker of shock than traditional vital signs alone. In previous literature, use of the reverse shock index (rSI), taken as SBP divided by HR, is recommended instead of SI for hospital...

journal_title：Critical care (London, England)

authors： Kimura A,Tanaka N

更新日期：2018-04-11 00:00:00

abstract：:Percutaneous dilatation tracheostomy in the intensive care setting presents an increasingly important concept for establishing a large-bore tracheal airway with minimal surgical intervention. Over the last years, different technical solutions have been studied to assess their respective risks and benefits to determine...

journal_title：Critical care (London, England)

authors： Brambrink A

更新日期：2004-10-01 00:00:00

abstract：:Since most common diseases have been shown to be influenced by inherited variations in our genes, completion of the Human Genome Project and mapping of the human genome single-nucleotide polymorphisms will have a tremendous impact on our approach to medicine. New developments in genotyping techniques and bioinformatic...

journal_title：Critical care (London, England)

authors： Chiche JD,Cariou A,Mira JP

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:N-acetylcysteine (NAC) has been shown to improve splanchnic blood flow in experimental studies. This report evaluates the effects of NAC on liver perfusion and lactate signal intensities in the liver tissue of septic shock patients using proton magnetic resonance imaging and spectroscopy. Furthermore, the mo...

journal_title：Critical care (London, England)

authors： Hein OV,Ohring R,Schilling A,Oellerich M,Armstrong VW,Kox WJ,Spies C

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the clinical usefulness of open lung biopsy (OLB) in patients undergoing mechanical ventilation for diffuse pulmonary infiltrates of unknown etiology. METHODS:This was a 10-year retrospective study in a 10-bed medical intensive care unit. The medical records of 36 v...

journal_title：Critical care (London, England)

authors： Lim SY,Suh GY,Choi JC,Koh WJ,Lim SY,Han J,Lee KS,Shim YM,Chung MP,Kim H,Kwon OJ

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Mechanical ventilators are increasingly used in critical care units. However, they can cause lung injury, including pulmonary edema. Our previous studies indicated that γ-aminobutyric acid (GABA) receptors are involved in alveolar-fluid homeostasis. The present study investigated the role of GABA receptors...

journal_title：Critical care (London, England)

authors： Chintagari NR,Liu L

更新日期：2012-12-12 00:00:00

abstract：INTRODUCTION:Sedation overuse is frequent and possibly associated with poor outcomes in the intensive care unit (ICU) patients. However, the association of early oversedation with clinical outcomes has not been thoroughly evaluated. The aim of this study was to assess the association of early sedation strategies with o...

journal_title：Critical care (London, England)

authors： Tanaka LM,Azevedo LC,Park M,Schettino G,Nassar AP,Réa-Neto A,Tannous L,de Souza-Dantas VC,Torelly A,Lisboa T,Piras C,Carvalho FB,Maia Mde O,Giannini FP,Machado FR,Dal-Pizzol F,de Carvalho AG,dos Santos RB,Tierno PF,

更新日期：2014-07-21 00:00:00

abstract：BACKGROUND:For patients who survive a critical illness and have their oral endotracheal tube removed, dysphagia is highly prevalent, and without intervention, it may persist far beyond hospital discharge. This pre- and post-intervention study with historical controls tested the effects of a swallowing and oral care (SO...

journal_title：Critical care (London, England)

authors： Wu CP,Xu YJ,Wang TG,Ku SC,Chan DC,Lee JJ,Wei YC,Hsiao TY,Chen CC

更新日期：2019-11-09 00:00:00

abstract：BACKGROUND:Early survival following severe injury has been improved with refined resuscitation strategies. Multiple organ dysfunction syndrome (MODS) is common among this fragile group of patients leading to prolonged hospital stay and late mortality. MODS after trauma is widely attributed to dysregulated inflammation ...

journal_title：Critical care (London, England)

authors： Manson J,Cole E,De'Ath HD,Vulliamy P,Meier U,Pennington D,Brohi K

更新日期：2016-06-07 00:00:00

abstract：INTRODUCTION AND METHODS:Dynamic fluorescence quenching is a technique that may overcome some of the limitations associated with measurement of tissue partial oxygen tension (PO2). We compared this technique with a polarographic Eppendorf needle electrode method using a saline tonometer in which the PO2 could be contro...

journal_title：Critical care (London, England)

authors： Shaw AD,Li Z,Thomas Z,Stevens CW

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Little is known about the development of acute lung injury outside the intensive care unit. We set out to document the following: the association between predefined clinical conditions and the development of acute lung injury by using the American-European consensus definition; the frequency of lung injury d...

journal_title：Critical care (London, England)

authors： Ferguson ND,Frutos-Vivar F,Esteban A,Gordo F,Honrubia T,Peñuelas O,Algora A,García G,Bustos A,Rodríguez I

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Ventilator-associated pneumonia (VAP) remains a common hazardous complication in mechanically ventilated patients and is associated with increased morbidity and mortality. We undertook a systematic review and meta-analysis of randomized controlled trials to assess the effect of toothbrushing as a component...

journal_title：Critical care (London, England)

authors： Gu WJ,Gong YZ,Pan L,Ni YX,Liu JC

更新日期：2012-10-12 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors of 14-day and 28-day mortality and develop a model for predicting 14-day and 28-day survival probability among adult hospitalized patients with COVID-19. METHODS:In this multicent...

journal_title：Critical care (London, England)

authors： Zhang S,Guo M,Duan L,Wu F,Hu G,Wang Z,Huang Q,Liao T,Xu J,Ma Y,Lv Z,Xiao W,Zhao Z,Tan X,Meng D,Zhang S,Zhou E,Yin Z,Geng W,Wang X,Zhang J,Chen J,Zhang Y,Jin Y

更新日期：2020-07-16 00:00:00

abstract：BACKGROUND:Oliguria is one of the leading triggers of fluid loading in patients in the intensive care unit (ICU). The purpose of this study was to assess the predictive value of urine Na(+) (uNa(+)) and other routine urine biomarkers for cardiac fluid responsiveness in oliguric ICU patients. METHODS:We conducted a pro...

journal_title：Critical care (London, England)

authors： Legrand M,Le Cam B,Perbet S,Roger C,Darmon M,Guerci P,Ferry A,Maurel V,Soussi S,Constantin JM,Gayat E,Lefrant JY,Leone M,support of the AZUREA network.

更新日期：2016-05-29 00:00:00

abstract：INTRODUCTION:Inter-hospital transport of critically ill patients is increasing. When performed by specialized retrieval teams there are less adverse events compared to transport by ambulance. These transports are performed with technical equipment also used in an Intensive Care Unit (ICU). As a consequence technical pr...

journal_title：Critical care (London, England)

authors： Droogh JM,Smit M,Hut J,de Vos R,Ligtenberg JJ,Zijlstra JG

更新日期：2012-02-12 00:00:00

abstract：INTRODUCTION:The study was conducted to validate in vivo the Adequacy Calculator, a Microsoft Excel-based program, designed to assess the prescription and delivery of renal replacement therapy in the critical care setting. METHODS:The design was a prospective cohort study, set in two intensive care units of teaching h...

journal_title：Critical care (London, England)

authors： Ricci Z,Salvatori G,Bonello M,Pisitkun T,Bolgan I,D'Amico G,Dan M,Piccinni P,Ronco C

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:Critical illness is commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycaemia, but not all severely ill develop hyperglycemia and some do even in mild disease. We hypothesised that acute disease only ...

journal_title：Critical care (London, England)

authors： Gornik I,Vujaklija-Brajkovic A,Renar IP,Gasparovic V

更新日期：2010-01-01 00:00:00

abstract：:SARS (severe acute respiratory syndrome) proved an enormous physical and emotional challenge to frontline health care workers throughout the world in late 2002 through to mid 2003. A large percentage of patients (many being health care workers themselves) became critically ill. Unfortunately, clinicians caring for the...

journal_title：Critical care (London, England)

authors： Gomersall CD

更新日期：2004-04-01 00:00:00