Assessment of tissue oxygen tension: comparison of dynamic fluorescence quenching and polarographic electrode technique.

abstract：INTRODUCTION:The main objective was to determine risk factors for presence of multidrug resistant bacteria (MDR) in postoperative peritonitis (PP) and optimal empirical antibiotic therapy (EA) among options proposed by Infectious Disease Society of America and the Surgical Infection Society guidelines. METHODS:One hun...

journal_title：Critical care (London, England)

authors： Augustin P,Kermarrec N,Muller-Serieys C,Lasocki S,Chosidow D,Marmuse JP,Valin N,Desmonts JM,Montravers P

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The respiratory variation in pulse pressure (PP) has been established as a dynamic variable of cardiac preload which indicates fluid responsiveness in mechanically ventilated patients. The impact of acute changes in cardiac performance on respiratory fluctuations in PP has not been evaluated until now. We ...

journal_title：Critical care (London, England)

authors： Keyl C,Stockinger J,Laule S,Staier K,Schiebeling-Römer J,Wiesenack C

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Extracorporeal lung assist, an extreme resource in patients with acute respiratory failure (ARF), is expanding its indications since knowledge about ventilator-induced lung injury has increased and protective ventilation has become the standard in ARF. METHODS:A prospective study on seven adult sheep was ...

journal_title：Critical care (London, England)

authors： Livigni S,Maio M,Ferretti E,Longobardo A,Potenza R,Rivalta L,Selvaggi P,Vergano M,Bertolini G

更新日期：2006-01-01 00:00:00

abstract：:Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables--events in the causal pathway between the exposure and the outcome--when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the an...

journal_title：Critical care (London, England)

authors： Schwaber MJ,Carmeli Y

更新日期：2006-01-01 00:00:00

abstract：:High-mobility group box 1 (HMGB1) is a DNA-binding protein that also exhibits proinflammatory cytokine-like activity. HMGB1 is passively released by necrotic cells and also is actively secreted by immunostimulated macrophages, dendritic cells, and enterocytes. Although circulating HMGB1 levels are increased relative t...

journal_title：Critical care (London, England)

authors： Fink MP

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Little is known about mortality rates following general surgical procedures in the United Kingdom. Deaths are most common in the 'high-risk' surgical population consisting mainly of older patients, with coexisting medical disease, who undergo major surgery. Only limited data are presently available to desc...

journal_title：Critical care (London, England)

authors： Pearse RM,Harrison DA,James P,Watson D,Hinds C,Rhodes A,Grounds RM,Bennett ED

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:In critically ill patients, delirium is a serious and frequent disorder that is associated with a prolonged intensive care and hospital stay and an increased morbidity and mortality. Without the use of a delirium screening instrument, delirium is often missed by ICU nurses and physicians. The effects of im...

journal_title：Critical care (London, England)

authors： van den Boogaard M,Pickkers P,van der Hoeven H,Roodbol G,van Achterberg T,Schoonhoven L

更新日期：2009-01-01 00:00:00

abstract：:Type 2 diabetes has reached epidemic proportions in many parts of the world. The disease is projected to continue to increase and double within the foreseeable future. Dysglycaemia develops in the form of hyperglycaemia, hypoglycaemia and marked glucose variability in critically ill adults whether they are known to ha...

journal_title：Critical care (London, England)

authors： Smith FG,Sheehy AM,Vincent JL,Coursin DB

更新日期：2010-01-01 00:00:00

abstract：:The forced oscillation technique (FOT) is a method for non-invasively assessing respiratory mechanics that is applicable both in paralysed and non-paralysed patients. As the FOT requires a minimal modification of the conventional ventilation setting and does not interfere with the ventilation protocol, the technique i...

journal_title：Critical care (London, England)

authors： Navajas D,Farré R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Critical illness following head injury is associated with a hypermetabolic state but there are insufficient epidemiological data describing acute nutrition delivery to this group of patients. Furthermore, there is little information describing relationships between nutrition and clinical outcomes in this pop...

journal_title：Critical care (London, England)

authors： Chapple LA,Chapman MJ,Lange K,Deane AM,Heyland DK

更新日期：2016-01-07 00:00:00

abstract：INTRODUCTION:Neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys-C), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic biomarkers of acute kidney injury (AKI). We aimed to determine the diagnostic properties of these biomarkers for detecting AKI in critically ill...

journal_title：Critical care (London, England)

authors： Dai X,Zeng Z,Fu C,Zhang S,Cai Y,Chen Z

更新日期：2015-05-06 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the clinical usefulness of open lung biopsy (OLB) in patients undergoing mechanical ventilation for diffuse pulmonary infiltrates of unknown etiology. METHODS:This was a 10-year retrospective study in a 10-bed medical intensive care unit. The medical records of 36 v...

journal_title：Critical care (London, England)

authors： Lim SY,Suh GY,Choi JC,Koh WJ,Lim SY,Han J,Lee KS,Shim YM,Chung MP,Kim H,Kwon OJ

更新日期：2007-01-01 00:00:00

abstract：:Considerable progress has been made in the past few years in the development of therapeutic interventions that can reduce mortality in sepsis. However, encouraging physicians to put the results of new studies into practice is not always simple. A roundtable was thus convened to provide guidance for clinicians on the i...

journal_title：Critical care (London, England)

authors： Vincent JL,Abraham E,Annane D,Bernard G,Rivers E,Van den Berghe G

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Hypernatraemia is common in inpatients and is associated with substantial morbidity. Its differential diagnosis is challenging, and delayed treatment may have devastating consequences. The most important hormone for the regulation of water homeostasis is arginine vasopressin, and copeptin, the C-terminal por...

journal_title：Critical care (London, England)

authors： Nigro N,Winzeler B,Suter-Widmer I,Schuetz P,Arici B,Bally M,Refardt J,Betz M,Gashi G,Urwyler SA,Burget L,Blum CA,Bock A,Huber A,Müller B,Christ-Crain M

更新日期：2018-02-09 00:00:00

abstract：INTRODUCTION:Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described. METHODS:Experimental endotoxemia (2 ng/kg Escherichia coli lipopolysaccharide [LPS]) was induced in 15 subjects, whereas 10 ser...

journal_title：Critical care (London, England)

authors： van den Boogaard M,Ramakers BP,van Alfen N,van der Werf SP,Fick WF,Hoedemaekers CW,Verbeek MM,Schoonhoven L,van der Hoeven JG,Pickkers P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Improving timeliness of pathogen identification is crucial to allow early adaptation of antibiotic therapy and improve prognosis in patients with pneumonia. We evaluated the relevance of a new syndromic rapid multiplex PCR test (rm-PCR) on respiratory samples to guide empirical antimicrobial therapy in adult...

journal_title：Critical care (London, England)

authors： Monard C,Pehlivan J,Auger G,Alviset S,Tran Dinh A,Duquaire P,Gastli N,d'Humières C,Maamar A,Boibieux A,Baldeyrou M,Loubinoux J,Dauwalder O,Cattoir V,Armand-Lefèvre L,Kernéis S,ADAPT study group.

更新日期：2020-07-14 00:00:00

abstract：:Stress hyperglycaemia is a common event in acute critical illness. There is increasing evidence that maintaining normoglycaemia and treatment with insulin (or with glucose-insulin-potassium [GIK]), even in non-diabetic persons, is helpful in limiting organ damage after myocardial infarction, stroke, traumatic brain in...

journal_title：Critical care (London, England)

authors： Johan Groeneveld AB,Beishuizen A,Visser FC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The properties of semi-elemental enteral nutrition might theoretically improve gastrointestinal tolerance in brain-injured patients, known to suffer gastroparesis. The purpose of this study was to compare the efficacy and tolerance of a semi-elemental versus a polymeric formula for enteral nutrition (EN) in ...

journal_title：Critical care (London, England)

authors： Carteron L,Samain E,Winiszewski H,Blasco G,Balon AS,Gilli C,Piton G,Capellier G,Pili-Floury S,Besch G

更新日期：2021-01-20 00:00:00

abstract：INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

journal_title：Critical care (London, England)

authors： Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Although less invasive than pulmonary artery catheters (PACs), arterial pulse pressure analysis techniques for estimating cardiac output (CO) have not been simultaneously compared to PAC bolus thermodilution CO (COtd) or continuous CO (CCO) devices. METHODS:We compared the accuracy, bias and trending abil...

journal_title：Critical care (London, England)

authors： Hadian M,Kim HK,Severyn DA,Pinsky MR

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:To systematically review studies evaluating the performance of Sequential Organ Failure Assessment (SOFA)-based models for predicting mortality in patients in the intensive care unit (ICU). METHODS:Medline, EMBASE and other databases were searched for English-language articles with the major objective of ...

journal_title：Critical care (London, England)

authors： Minne L,Abu-Hanna A,de Jonge E

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is a frequent complication after cardiac surgery with cardiopulmonary bypass in infants. Renal near-infrared spectroscopy (NIRS) is used to evaluate regional oximetry in a non-invasive continuous real-time fashion, and reflects tissue perfusion. The aim of this study was to evalua...

journal_title：Critical care (London, England)

authors： Ruf B,Bonelli V,Balling G,Hörer J,Nagdyman N,Braun SL,Ewert P,Reiter K

更新日期：2015-01-29 00:00:00

abstract：:Platelet transfusions carry greater risks of infection, sepsis, and death than any other blood product, owing primarily to bacterial contamination. Many patients may be at particular risk, including critically ill patients in the intensive care unit. This narrative review provides an overview of the problem and an upd...

journal_title：Critical care (London, England)

authors： Levy JH,Neal MD,Herman JH

更新日期：2018-10-27 00:00:00

abstract：:In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest...

journal_title：Critical care (London, England)

authors： Walker PF,Buehner MF,Wood LA,Boyer NL,Driscoll IR,Lundy JB,Cancio LC,Chung KK

更新日期：2015-10-28 00:00:00

abstract：INTRODUCTION:The mortality benefit of whole-body computed tomography (CT) in early trauma management remains controversial and poorly understood. The objective of this study was to assess the impact of whole-body CT compared with selective CT on mortality and management of patients with severe blunt trauma. METHODS:Th...

journal_title：Critical care (London, England)

authors： Yeguiayan JM,Yap A,Freysz M,Garrigue D,Jacquot C,Martin C,Binquet C,Riou B,Bonithon-Kopp C,FIRST Study Group.

更新日期：2012-06-11 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether using pharmacodynamic-based dosing of antimicrobials, such as extended/continuous infusions, in critically ill patients is associated with improved outcomes as compared with traditional dosing methods. METHODS:We searched Medline, HealthStar, EMBASE, Cochrane...

journal_title：Critical care (London, England)

authors： Chant C,Leung A,Friedrich JO

更新日期：2013-11-29 00:00:00

abstract：INTRODUCTION:Diclofenac, a nonsteroidal antiinflammatory drug, is commonly used as antipyretic therapy in intensive care. The purpose of this study was to investigate the effects of parenteral diclofenac infusion on brain homeostasis, including brain-tissue oxygen tension (PbtO2) and brain metabolism after aneurysmal s...

journal_title：Critical care (London, England)

authors： Schiefecker AJ,Pfausler B,Beer R,Sohm F,Sabo J,Knauseder V,Fischer M,Dietmann A,Hackl WO,Thomé C,Schmutzhard E,Helbok R

更新日期：2013-05-12 00:00:00

abstract：INTRODUCTION:Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to evaluate a four-region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care unit. METHODS:Fift...

journal_title：Critical care (London, England)

authors： Enghard P,Rademacher S,Nee J,Hasper D,Engert U,Jörres A,Kruse JM

更新日期：2015-02-06 00:00:00

abstract：:Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. Recent work aiming to summarize the evidence assessed the effect of a procalcitonin (PCT)-guided antibiotic treatment on outcomes in acute lower respiratory trac...

journal_title：Critical care (London, England)

authors： Lisboa T,Salluh J,Povoa P

更新日期：2018-01-27 00:00:00

abstract：BACKGROUND:Higher inspiratory airway pressures are associated with worse outcomes in mechanically ventilated patients with the acute respiratory distress syndrome (ARDS). This relationship, however, has not been well investigated in patients without ARDS. We hypothesized that higher driving pressures (ΔP) and plateau p...

journal_title：Critical care (London, England)

authors： Sahetya SK,Mallow C,Sevransky JE,Martin GS,Girard TD,Brower RG,Checkley W,Society of Critical Care Medicine Discovery Network Critical Illness Outcomes Study Investigators.

更新日期：2019-11-21 00:00:00