Standardisation of data collection in traumatic brain injury: key to the future?

abstract：INTRODUCTION:The objective was to study the effects of a novel lung volume optimization procedure (LVOP) using high-frequency oscillatory ventilation (HFOV) upon gas exchange, the transpulmonary pressure (TPP), and hemodynamics in a porcine model of surfactant depletion. METHODS:With institutional review board approva...

journal_title：Critical care (London, England)

authors： Karmrodt J,David M,Yuan S,Markstaller K

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Dysbiosis of intestinal microbiota likely plays an important role in the development of gut-derived infections, making it a potential therapeutic target against sepsis. However, experience with fecal microbiota transplantation (FMT) in the treatment of sepsis and knowledge of the underlying mechanisms are ...

journal_title：Critical care (London, England)

authors： Li Q,Wang C,Tang C,He Q,Zhao X,Li N,Li J

更新日期：2015-02-09 00:00:00

abstract：:Adverse events affect approximately 3% to 12% of hospitalized patients. At least a third, but as many as half, of such events are considered preventable. Detection of these events requires investments of time and money. A report in a recent issue of Critical Care used the medical emergency team activation as a trigger...

journal_title：Critical care (London, England)

authors： Amaral AC,Shojania KG

更新日期：2009-01-01 00:00:00

abstract：:Vasopressin (antidiuretic hormone) is emerging as a potentially major advance in the treatment of septic shock. Terlipressin (tricyl-lysine-vasopressin) is the synthetic, long-acting analogue of vasopressin, and has comparable pharmacodynamic but different pharmacokinetic properties. Vasopressin mediates vasoconstrict...

journal_title：Critical care (London, England)

authors： Delmas A,Leone M,Rousseau S,Albanèse J,Martin C

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Delivery of bronchodilators with a metered-dose inhaler (MDI) and a spacer device in mechanically ventilated patients has become a widespread practice. However, except for the short-acting beta2-agonist salbutamol, the duration of action of other bronchodilators, including long-acting beta2-agonists, deliv...

journal_title：Critical care (London, England)

authors： Malliotakis P,Linardakis M,Gavriilidis G,Georgopoulos D

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Mechanical ventilation (MV) with high tidal volumes may induce or aggravate lung injury in critical ill patients. We compared the effects of a protective versus a conventional ventilatory strategy, on systemic and lung production of tumor necrosis factor-alpha (TNF-alpha) and interleukin-8 (IL-8) in patien...

journal_title：Critical care (London, England)

authors： Pinheiro de Oliveira R,Hetzel MP,dos Anjos Silva M,Dallegrave D,Friedman G

更新日期：2010-01-01 00:00:00

abstract：:Bacterial pathogens possess an array of specific mechanisms that confer virulence and the capacity to avoid host defence mechanisms. Mechanisms of virulence are often mediated by the subversion of normal aspects of host biology. In this way the pathogen modifies host function so as to promote the pathogen's survival o...

journal_title：Critical care (London, England)

authors： Webb SA,Kahler CM

更新日期：2008-01-01 00:00:00

abstract：:Antithrombotic prophylaxis in critically ill patients frequently fails. Venous thromboembolism is associated with adverse clinical outcomes, including a prolonged intensive care unit stay and death. A potential mechanism by which critically ill patients may be predisposed to antithrombotic failure is the inability to ...

journal_title：Critical care (London, England)

authors： Crowther M,Lim W

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Hyperbilirubinaemia is a common occurrence in patients who are admitted to intensive care units (ICUs) after major surgery, and it is associated with high mortality. We investigated the incidence of hyperbilirubinaemia after two major types of thoracic surgery: open-heart surgery and oesophagectomy. In order...

journal_title：Critical care (London, England)

authors： Hosotsubo KK,Nishimura M,Nishimura S

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:The endothelial specific angiopoietin (Ang)-Tie2 ligand-receptor system has been identified as a non-redundant mediator of endothelial activation in experimental sepsis. Binding of circulating Ang-1 to the Tie2 receptor protects the vasculature from inflammation and leakage, whereas binding of Ang-2 antago...

journal_title：Critical care (London, England)

authors： Kümpers P,Lukasz A,David S,Horn R,Hafer C,Faulhaber-Walter R,Fliser D,Haller H,Kielstein JT

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION AND METHODS:Dynamic fluorescence quenching is a technique that may overcome some of the limitations associated with measurement of tissue partial oxygen tension (PO2). We compared this technique with a polarographic Eppendorf needle electrode method using a saline tonometer in which the PO2 could be contro...

journal_title：Critical care (London, England)

authors： Shaw AD,Li Z,Thomas Z,Stevens CW

更新日期：2002-02-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2020. Further information about the Annual Update in Intensive Care and Emergency Medicine is available ...

journal_title：Critical care (London, England)

authors： Jonkman AH,de Vries HJ,Heunks LMA

更新日期：2020-03-24 00:00:00

abstract：INTRODUCTION:Early multimodal treatment of severe sepsis, including the use of drotrecogin alfa (activated) (DrotAA) when indicated, is considered essential for optimum outcome. However, predicting which infected patients will progress to severe sepsis and the need for aggressive intervention continues to be problemati...

journal_title：Critical care (London, England)

authors： Hodder RV,Hall R,Russell JA,Fisher HN,Lee B

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. METHODS:A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal...

journal_title：Critical care (London, England)

authors： Bassetti M,Giacobbe DR,Vena A,Trucchi C,Ansaldi F,Antonelli M,Adamkova V,Alicino C,Almyroudi MP,Atchade E,Azzini AM,Carannante N,Carnelutti A,Corcione S,Cortegiani A,Dimopoulos G,Dubler S,García-Garmendia JL,Girardis

更新日期：2019-06-14 00:00:00

abstract：INTRODUCTION:Blood transfusion in the perioperative period has frequently been associated with an excess of nosocomial infections. Whilst transfused whole blood induces specific host immune alteration that may predispose to nosocomial infections, the immunomodulating properties associated with leukodepleted blood remai...

journal_title：Critical care (London, England)

authors： Fragkou PC,Torrance HD,Pearse RM,Ackland GL,Prowle JR,Owen HC,Hinds CJ,O'Dwyer MJ

更新日期：2014-10-01 00:00:00

abstract：:Prone ventilation (PV) is a ventilatory strategy that frequently improves oxygenation and lung mechanics in critical illness, yet does not consistently improve survival. While the exact physiologic mechanisms related to these benefits remain unproven, one major theoretical mechanism relates to reducing the abdominal e...

journal_title：Critical care (London, England)

authors： Kirkpatrick AW,Pelosi P,De Waele JJ,Malbrain ML,Ball CG,Meade MO,Stelfox HT,Laupland KB

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Abdominal distension is common in critical illness. There is a growing recognition that intra-abdominal hypertension (IAH) may complicate nonsurgical critical illness as well as after abdominal surgery. However, the pathophysiological basis of the injury to the intestinal mucosal barrier and its influence ...

journal_title：Critical care (London, England)

authors： Cheng J,Wei Z,Liu X,Li X,Yuan Z,Zheng J,Chen X,Xiao G,Li X

更新日期：2013-12-09 00:00:00

abstract：:Certain noble gases, though inert, exhibit remarkable biological properties. Notably, xenon and argon provide neuroprotection in animal models of central nervous system injury. In the previous issue of Critical Care, Loetscher and colleagues provided further evidence that argon may have therapeutic properties for neur...

journal_title：Critical care (London, England)

authors： Sanders RD,Ma D,Maze M

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Sepsis-induced immunosuppression may result in death. The mechanisms of immune suppression include loss of macrophage and monocyte expression of the major histocompatibility complex, increased anti-inflammatory cytokine expression and decreased expression of proinflammatory cytokines. In this study, we sou...

journal_title：Critical care (London, England)

authors： Wu HP,Shih CC,Lin CY,Hua CC,Chuang DY

更新日期：2011-01-01 00:00:00

abstract：:The recent bus crash in Switzerland involving many children provides several lessons for the pre-hospital care community. The use of multiple helicopters that are capable of flying at night and that carry advanced medical pre-hospital teams undoubtedly saved lives following the tragedy. We describe the medical respons...

journal_title：Critical care (London, England)

authors： Lyon RM,Sanders J

更新日期：2012-07-11 00:00:00

abstract：:This review presents key publications from the research field of sepsis published in Critical Care and other relevant journals during 2013. The results of these experimental studies and clinical trials are discussed in the context of current scientific and clinical background. The discussion highlights and summarises ...

journal_title：Critical care (London, England)

authors： de Montmollin E,Annane D

更新日期：2014-10-15 00:00:00

abstract：INTRODUCTION:Transthoracic echocardiography (TTE) is a useful tool for minimally invasive hemodynamic monitoring in the ICU. Dynamic indices (such as the inferior vena cava distensibility index (dIVC)) can be used to predict fluid responsiveness in mechanically ventilated patients. Although quantitative use of the dIVC...

journal_title：Critical care (London, England)

authors： Duwat A,Zogheib E,Guinot P,Levy F,Trojette F,Diouf M,Slama M,Dupont H

更新日期：2014-01-14 00:00:00

abstract：:Since most common diseases have been shown to be influenced by inherited variations in our genes, completion of the Human Genome Project and mapping of the human genome single-nucleotide polymorphisms will have a tremendous impact on our approach to medicine. New developments in genotyping techniques and bioinformatic...

journal_title：Critical care (London, England)

authors： Chiche JD,Cariou A,Mira JP

更新日期：2002-06-01 00:00:00

abstract：:Hydrogen sulfide (H2S), a gas with the characteristic odor of rotten eggs, is known for its toxicity and as an environmental hazard, inhibition of mitochondrial respiration resulting from blockade of cytochrome c oxidase being the main toxic mechanism. Recently, however, H2S has been recognized as a signaling molecule...

journal_title：Critical care (London, England)

authors： Wagner F,Asfar P,Calzia E,Radermacher P,Szabó C

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:This study aimed to examine the long-term outcome for patients with end-stage renal failure (ESRF) who survived multiple-organ failure. METHODS:We performed a review of databases from the renal medicine service and intensive care units (ICU) of the participating hospitals within Imperial College Healthcar...

journal_title：Critical care (London, England)

authors： Chapman RJ,Templeton M,Ashworth S,Broomhead R,McLean A,Brett SJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the incidence of organ failure in trauma patients treated in an intensive care unit (ICU), and to study the relationship between organ failure and long-term survival and functional status. METHODS:This is a cohort study of all adult ICU trauma patients admitted to a unive...

journal_title：Critical care (London, England)

authors： Ulvik A,Kvåle R,Wentzel-Larsen T,Flaatten H

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Metformin-associated lactic acidosis (MALA) is a classic side effect of metformin and is known to be a severe disease with a high mortality rate. The treatment of MALA with dialysis is controversial and is the subject of many case reports in the literature. We aimed to assess the prevalence of MALA in a 16...

journal_title：Critical care (London, England)

authors： Peters N,Jay N,Barraud D,Cravoisy A,Nace L,Bollaert PE,Gibot S

更新日期：2008-01-01 00:00:00

abstract：:Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. Recent work aiming to summarize the evidence assessed the effect of a procalcitonin (PCT)-guided antibiotic treatment on outcomes in acute lower respiratory trac...

journal_title：Critical care (London, England)

authors： Lisboa T,Salluh J,Povoa P

更新日期：2018-01-27 00:00:00

abstract：:The European Clinical Trials Directive requires an informed consent from the patient or a proxy in drug trials. Although informed consent is a valuable tool to protect patients' rights in clinical trials, this requirement largely impedes research in critical care settings, and if pursued in this context, it does not p...

journal_title：Critical care (London, England)

authors： Berg RM,Møller K,Rossel PJ

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Severe acute pancreatitis (SAP) requiring admission to a critical care unit is associated with high mortality and long lengths of stay. We describe the case mix, outcome, and activity of admissions with SAP who were identified from a high-quality clinical database. METHODS:We conducted a secondary analysi...

journal_title：Critical care (London, England)

authors： Harrison DA,D'Amico G,Singer M

更新日期：2007-01-01 00:00:00