Recognition of hypovolemic shock: using base deficit to think outside of the ATLS box.

abstract：INTRODUCTION:The choice of invasive systemic haemodynamic monitoring in critically ill patients remains controversial as no multicentre comparative clinical data exist. Accordingly, we sought to study and compare the features and outcomes of patients who receive haemodynamic monitoring with either the pulmonary artery ...

journal_title：Critical care (London, England)

authors： Uchino S,Bellomo R,Morimatsu H,Sugihara M,French C,Stephens D,Wendon J,Honore P,Mulder J,Turner A,PAC\/PiCCO Use and Likelihood of Success Evaluation PULSE Study Group.

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Improving timeliness of pathogen identification is crucial to allow early adaptation of antibiotic therapy and improve prognosis in patients with pneumonia. We evaluated the relevance of a new syndromic rapid multiplex PCR test (rm-PCR) on respiratory samples to guide empirical antimicrobial therapy in adult...

journal_title：Critical care (London, England)

authors： Monard C,Pehlivan J,Auger G,Alviset S,Tran Dinh A,Duquaire P,Gastli N,d'Humières C,Maamar A,Boibieux A,Baldeyrou M,Loubinoux J,Dauwalder O,Cattoir V,Armand-Lefèvre L,Kernéis S,ADAPT study group.

更新日期：2020-07-14 00:00:00

abstract：INTRODUCTION:Circulatory failure during brain death organ donor resuscitation is a problem that compromises recovery of organs. Combined administration of steroid, thyroxine and vasopressin has been proposed to optimize the management of brain deceased donors before recovery of organs. However the single administration...

journal_title：Critical care (London, England)

authors： Pinsard M,Ragot S,Mertes PM,Bleichner JP,Zitouni S,Cook F,Pierrot M,Dube L,Menguy E,Lefèvre LM,Escaravage L,Dequin PF,Vignon P,Pichon N

更新日期：2014-07-23 00:00:00

abstract：INTRODUCTION:The ventilator and the endotracheal tube impose additional workload in mechanically ventilated patients breathing spontaneously. The total work of breathing (WOB) includes elastic and resistive work. In a bench test we assessed the imposed WOB using 3100 A/3100 B SensorMedics high-frequency oscillatory ven...

journal_title：Critical care (London, England)

authors： van Heerde M,van Genderingen HR,Leenhoven T,Roubik K,Plötz FB,Markhorst DG

更新日期：2006-02-01 00:00:00

abstract：:The burden of chronic obstructive pulmonary disease on intensive care is heavy, but newer modalities of treatment are now available to improve outcomes. Cardiac-based research continues to generate new drugs and tests to better outcome and aid in early diagnosis. And how do various intensive care interventions compare...

journal_title：Critical care (London, England)

authors： Bandarupalli UM,Williams GD

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Glial fibrillary acidic protein (GFAP) may serve as a serum marker of traumatic brain injury (TBI) that can be used to monitor biochemical changes in patients and gauge the response to treatment. However, the temporal profile of serum GFAP in the acute period of brain injury and the associated utility for ...

journal_title：Critical care (London, England)

authors： Lei J,Gao G,Feng J,Jin Y,Wang C,Mao Q,Jiang J

更新日期：2015-10-12 00:00:00

abstract：INTRODUCTION:The FloTrac/Vigileo (Edwards Lifesciences, Irvine, CA, USA) allows pulse pressure-derived cardiac output measurement without external calibration. Software modifications were performed in order to eliminate initially observed deficits. The aim of this study was to assess changes in cardiac output determine...

journal_title：Critical care (London, England)

authors： Senn A,Button D,Zollinger A,Hofer CK

更新日期：2009-01-01 00:00:00

abstract：:In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflammatory effects afte...

journal_title：Critical care (London, England)

authors： Zhang H

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The dysregulated host immune response that defines sepsis varies as a function of both the immune status of the host and the distinct nature of the pathogen. The degree to which immunocompromising comorbidities or immunosuppressive medications affect the immune response to infection is poorly understood beca...

journal_title：Critical care (London, England)

authors： Greenberg JA,Hrusch CL,Jaffery MR,David MZ,Daum RS,Hall JB,Kress JP,Sperling AI,Verhoef PA

更新日期：2018-04-25 00:00:00

abstract：INTRODUCTION:Blood transfusion is associated with increased morbidity and mortality in cardiac surgery patients, but cause-and-effect relations remain unknown. We hypothesized that blood transfusion is associated with changes in pulmonary and systemic inflammation and coagulation occurring in patients who do not meet t...

journal_title：Critical care (London, England)

authors： Tuinman PR,Vlaar AP,Cornet AD,Hofstra JJ,Levi M,Meijers JC,Beishuizen A,Schultz MJ,Groeneveld AJ,Juffermans NP

更新日期：2011-01-01 00:00:00

abstract：:Primary or secondary infection of necrotized areas by enteral bacteria is considered a primary cause of mortality in patients with severe acute pancreatitis (SAP). Indeed, 20-30% of patients die during the course of the disease from multiple organ dysfunction after infection. This is why strategies such as antibiotic ...

journal_title：Critical care (London, England)

authors： Gerlach H

更新日期：2004-12-01 00:00:00

abstract：:Body cell mass (BCM) is the metabolically active cell mass involved in O₂ consumption, CO₂ production and energy expenditure. BCM measurement has been suggested as a tool for the evaluation of nutritional status. Since BCM is closely related to energy expenditure, it could also represent a good reference value for the...

journal_title：Critical care (London, England)

authors： Fiaccadori E,Morabito S,Cabassi A,Regolisti G

更新日期：2014-05-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) has a substantial mortality rate and annually affects more than 140,000 people in the USA alone. Standard management includes lung protective ventilation but this impairs carbon dioxide clearance and may lead to right heart dysfunction or increased intracranial pressure. Extr...

journal_title：Critical care (London, England)

authors： Cove ME,MacLaren G,Federspiel WJ,Kellum JA

更新日期：2012-09-21 00:00:00

abstract：INTRODUCTION:Economic evaluations of interventions in the hospital setting often rely on the estimated long-term impact on patient survival. Estimates of mortality rates and long-term outcomes among patients discharged alive from the intensive care unit (ICU) are lacking from lower- and middle-income countries. This st...

journal_title：Critical care (London, England)

authors： Luangasanatip N,Hongsuwan M,Lubell Y,Limmathurotsakul D,Teparrukkul P,Chaowarat S,Day NP,Graves N,Cooper BS

更新日期：2013-10-03 00:00:00

abstract：INTRODUCTION:Metformin-associated lactic acidosis (MALA) is a classic side effect of metformin and is known to be a severe disease with a high mortality rate. The treatment of MALA with dialysis is controversial and is the subject of many case reports in the literature. We aimed to assess the prevalence of MALA in a 16...

journal_title：Critical care (London, England)

authors： Peters N,Jay N,Barraud D,Cravoisy A,Nace L,Bollaert PE,Gibot S

更新日期：2008-01-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015. Further information about the Annual Update in Intensive Care a...

journal_title：Critical care (London, England)

authors： Sandroni C,D'Arrigo S,Antonelli M

更新日期：2015-03-16 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2019. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2019 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available...

journal_title：Critical care (London, England)

authors： Milford EM,Reade MC

更新日期：2019-03-09 00:00:00

abstract：:Coronavirus disease (COVID-19) is an emerging viral infection that is rapidly spreading across the globe. SARS-CoV-2 belongs to the same coronavirus class that caused respiratory illnesses such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). During the SARS and MERS outbreaks, ...

journal_title：Critical care (London, England)

authors： Kaur R,Weiss TT,Perez A,Fink JB,Chen R,Luo F,Liang Z,Mirza S,Li J

更新日期：2020-09-23 00:00:00

abstract：:Glucocorticoid use in sepsis is controversial. In contrast to other extracellular signaling molecules, glucocorticoid receptors (GRs) are intra-cytoplasmic. Several GR isoforms have been identified. A study in Critical Care Forum suggests that sepsis alters the abundance of the dominant negative GRβ. Here we discuss G...

journal_title：Critical care (London, England)

authors： Deutschman CS

更新日期：2013-06-27 00:00:00

abstract：INTRODUCTION:Patients admitted to the intensive care unit often develop hyperglycaemia, but the underlying mechanisms have not been fully described. The incretin effect is reduced in patients with type 2 diabetes. Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resis...

journal_title：Critical care (London, England)

authors： Nielsen ST,Janum S,Krogh-Madsen R,Solomon TP,Møller K

更新日期：2015-11-16 00:00:00

abstract：:Refractory cardiac shock in the cardiac surgical intensive care unit confers significant morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) has become a common intervention for refractory cardiogenic shock when other therapies have failed. However, it is difficult to predict who will benefit from this...

journal_title：Critical care (London, England)

authors： Stephens R,Fan E

更新日期：2014-02-20 00:00:00

abstract：:Venovenous extracorporeal membrane oxygenation (vv-ECMO) has been classically employed as a rescue therapy for patients with respiratory failure not treatable with conventional mechanical ventilation alone. In recent years, however, the timing of ECMO initiation has been readdressed and ECMO is often started earlier i...

journal_title：Critical care (London, England)

authors： Langer T,Santini A,Bottino N,Crotti S,Batchinsky AI,Pesenti A,Gattinoni L

更新日期：2016-06-30 00:00:00

abstract：BACKGROUND:Severe traumatic brain injury (TBI) has been increasing with greater incidence of injuries from traffic or sporting accidents. Although there are a number of animal models of TBI using progesterone for head injury, the effects of progesterone on neurologic outcome of acute TBI patients remain unclear. The ai...

journal_title：Critical care (London, England)

authors： Xiao G,Wei J,Yan W,Wang W,Lu Z

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Blood transfusion in the perioperative period has frequently been associated with an excess of nosocomial infections. Whilst transfused whole blood induces specific host immune alteration that may predispose to nosocomial infections, the immunomodulating properties associated with leukodepleted blood remai...

journal_title：Critical care (London, England)

authors： Fragkou PC,Torrance HD,Pearse RM,Ackland GL,Prowle JR,Owen HC,Hinds CJ,O'Dwyer MJ

更新日期：2014-10-01 00:00:00

abstract：:In the publication of this article [1], there are 4 collaborating authors missing from the 'MARS consortium'. This has now been included in this correction article. ...

journal_title：Critical care (London, England)

authors： Klein Klouwenberg PMC,Spitoni C,van der Poll T,Bonten MJ,Cremer OL,MARS consortium.

更新日期：2020-02-06 00:00:00

abstract：:Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, i...

journal_title：Critical care (London, England)

authors： Berger D,Takala J

更新日期：2016-06-09 00:00:00

abstract：:In a group of postoperative patients, Taniguchi and coworkers compared the effect of a computerized system for weaning against 'manual care'. The computerized system involved automatic adjustments to the level of pressure support to achieve a target respiratory rate. Manual care involved adjustments to the level of pr...

journal_title：Critical care (London, England)

authors： Adigüzel N,Güngör G,Tobin MJ

更新日期：2009-01-01 00:00:00

abstract：:The use of extracorporeal cardiopulmonary resuscitation (ECPR) to restore circulation during cardiac arrest is a time-critical, resource-intensive intervention of unproven efficacy. The current COVID-19 pandemic has brought additional complexity and significant barriers to the ongoing provision and implementation of E...

journal_title：Critical care (London, England)

authors： Worku E,Gill D,Brodie D,Lorusso R,Combes A,Shekar K

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:There is growing interest in patient outcomes following critical illness, with an increasing number and different types of studies conducted, and a need for synthesis of existing findings to help inform the field. For this purpose we conducted a systematic review of qualitative studies evaluating patient out...

journal_title：Critical care (London, England)

authors： Hashem MD,Nallagangula A,Nalamalapu S,Nunna K,Nausran U,Robinson KA,Dinglas VD,Needham DM,Eakin MN

更新日期：2016-10-26 00:00:00

abstract：:Mechanically ventilated, intubated patients are at increased risk for tracheal colonization with bacterial pathogens that may progress to heavy bacterial colonization, ventilator-associated tracheobronchitis (VAT), and/or ventilator-associated pneumonia (VAP). Previous studies report that 10 to 30 % of patients with V...

journal_title：Critical care (London, England)

authors： Craven DE,Hudcova J,Lei Y,Craven KA,Waqas A

更新日期：2016-09-29 00:00:00