Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure.

abstract：INTRODUCTION:Ventilation according to the open lung concept (OLC) consists of recruitment maneuvers, followed by low tidal volume and high positive end-expiratory pressure, aiming at minimizing atelectasis. The minimization of atelectasis reduces the right ventricular (RV) afterload, but the increased intrathoracic pre...

journal_title：Critical care (London, England)

authors： Miranda DR,Klompe L,Cademartiri F,Haitsma JJ,Palumbo A,Takkenberg JJ,Lachmann B,Bogers AJ,Gommers D

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Exposure to hyperoxemia and hypoxemia is common in out-of-hospital cardiac arrest (OHCA) patients following return of spontaneous circulation (ROSC), but its effects on neurological outcome are uncertain, and study results are inconsistent. METHODS:Exploratory post hoc substudy of the Target Temperature Mana...

journal_title：Critical care (London, England)

authors： Ebner F,Ullén S,Åneman A,Cronberg T,Mattsson N,Friberg H,Hassager C,Kjærgaard J,Kuiper M,Pelosi P,Undén J,Wise MP,Wetterslev J,Nielsen N

更新日期：2019-01-28 00:00:00

abstract：:Critical care medicine in China has made great advances in recent decades. This has led to an unavoidable issue: end-of-life ethics. With advances in medical technology and therapeutics allowing the seemingly limitless maintenance of life, the exact time of death of an individual patient is often determined by the dec...

journal_title：Critical care (London, England)

authors： Li LB

更新日期：2013-12-04 00:00:00

abstract：INTRODUCTION:Sedation overuse is frequent and possibly associated with poor outcomes in the intensive care unit (ICU) patients. However, the association of early oversedation with clinical outcomes has not been thoroughly evaluated. The aim of this study was to assess the association of early sedation strategies with o...

journal_title：Critical care (London, England)

authors： Tanaka LM,Azevedo LC,Park M,Schettino G,Nassar AP,Réa-Neto A,Tannous L,de Souza-Dantas VC,Torelly A,Lisboa T,Piras C,Carvalho FB,Maia Mde O,Giannini FP,Machado FR,Dal-Pizzol F,de Carvalho AG,dos Santos RB,Tierno PF,

更新日期：2014-07-21 00:00:00

abstract：INTRODUCTION:The goal of the current study was to investigate the effect of aging on the development of endothelial dysfunction in a murine model of sepsis, and to compare it with the effect of genetic deficiency of the endothelial isoform of nitric oxide synthase (eNOS). METHODS:Cecal ligation and puncture (CLP) was ...

journal_title：Critical care (London, England)

authors： Coletta C,Módis K,Oláh G,Brunyánszki A,Herzig DS,Sherwood ER,Ungvári Z,Szabo C

更新日期：2014-09-16 00:00:00

abstract：BACKGROUND:Improving timeliness of pathogen identification is crucial to allow early adaptation of antibiotic therapy and improve prognosis in patients with pneumonia. We evaluated the relevance of a new syndromic rapid multiplex PCR test (rm-PCR) on respiratory samples to guide empirical antimicrobial therapy in adult...

journal_title：Critical care (London, England)

authors： Monard C,Pehlivan J,Auger G,Alviset S,Tran Dinh A,Duquaire P,Gastli N,d'Humières C,Maamar A,Boibieux A,Baldeyrou M,Loubinoux J,Dauwalder O,Cattoir V,Armand-Lefèvre L,Kernéis S,ADAPT study group.

更新日期：2020-07-14 00:00:00

abstract：: ...

journal_title：Critical care (London, England)

authors： Honore PM,De Bels D,Kugener L,Redant S,Attou R,Gallerani A,Spapen HD

更新日期：2019-01-09 00:00:00

abstract：:There is a paradigm shift happening for sepsis. Sepsis is no longer solely conceptualized as problem of individual patients treated in emergency departments and intensive care units but also as one that is addressed as public health issue with population- and systems-based solutions. We offer a conceptual framework fo...

journal_title：Critical care (London, England)

authors： Kempker JA,Wang HE,Martin GS

更新日期：2018-05-06 00:00:00

abstract：INTRODUCTION:Our understanding of septic acute kidney injury (AKI) remains incomplete. A fundamental step is the use of animal models designed to meet the criteria of human sepsis. Therefore, we dynamically assessed renal haemodynamic, microvascular and metabolic responses to, and ultrastructural sequelae of, sepsis in...

journal_title：Critical care (London, England)

authors： Chvojka J,Sykora R,Krouzecky A,Radej J,Varnerova V,Karvunidis T,Hes O,Novak I,Radermacher P,Matejovic M

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Identifying patients who need damage control resuscitation (DCR) early after trauma is pivotal for adequate management of their critical condition. Several trauma-scoring systems have been developed to identify such patients, but most of them are not simple enough to be used in prehospital settings in the ...

journal_title：Critical care (London, England)

authors： Tonglet ML,Minon JM,Seidel L,Poplavsky JL,Vergnion M

更新日期：2014-11-26 00:00:00

abstract：BACKGROUND:Microcirculatory dysfunction develops in both septic and cardiogenic shock patients, and it is associated with poor prognosis in patients with septic shock. Information on the association between microcirculatory dysfunction and prognosis in cardiogenic shock patients with venoarterial extracorporeal membran...

journal_title：Critical care (London, England)

authors： Yeh YC,Lee CT,Wang CH,Tu YK,Lai CH,Wang YC,Chao A,Huang CH,Cheng YJ,Chen YS,NTUH Center of Microcirculation Medical Research (NCMMR).

更新日期：2018-08-19 00:00:00

abstract：:Cardiogenic shock is a lethal condition. Physicians are searching for hemodynamic markers which could help risk-stratification of patients in this picture. Torgersen and coworkers present an hourly time integral of the cardiac power index and cardiac index drops to predict outcomes in the setting of cardiogenic shock....

journal_title：Critical care (London, England)

authors： Yilmaz MB,Mebazaa A

更新日期：2009-01-01 00:00:00

abstract：:Until relatively recently, critical illness was considered as a separate entity and the intensive care unit (ICU), often a little cut-off from other areas of the hospital, was in many cases used as a last resort for patients so severely ill that it was no longer possible to care for them on the general ward. However, ...

journal_title：Critical care (London, England)

authors： Vincent JL

更新日期：2019-06-14 00:00:00

abstract：BACKGROUND:The first FDA-approved test to assess risk for acute kidney injury (AKI), [TIMP-2]•[IGFBP7], is clinically available in many parts of the world, including the USA and Europe. We sought to understand how the test is currently being used clinically. METHODS:We invited a group of experts knowledgeable on the u...

journal_title：Critical care (London, England)

authors： Guzzi LM,Bergler T,Binnall B,Engelman DT,Forni L,Germain MJ,Gluck E,Göcze I,Joannidis M,Koyner JL,Reddy VS,Rimmelé T,Ronco C,Textoris J,Zarbock A,Kellum JA

更新日期：2019-06-20 00:00:00

abstract：INTRODUCTION:This study aimed to examine the long-term outcome for patients with end-stage renal failure (ESRF) who survived multiple-organ failure. METHODS:We performed a review of databases from the renal medicine service and intensive care units (ICU) of the participating hospitals within Imperial College Healthcar...

journal_title：Critical care (London, England)

authors： Chapman RJ,Templeton M,Ashworth S,Broomhead R,McLean A,Brett SJ

更新日期：2009-01-01 00:00:00

abstract：:Large quantitaties of inflammatory mediators are released during the course of endotoxaemia. These mediators in turn can stimulate the sympathetic nervous system (SNS) to release catecholamines, which ultimately regulate inflammation-associated impairment in tissue perfusion, myocardial impairment and vasodilatation. ...

journal_title：Critical care (London, England)

authors： Beck GCh,Brinkkoetter P,Hanusch C,Schulte J,van Ackern K,van der Woude FJ,Yard BA

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Optimal glycaemic targets in traumatic brain injury (TBI) remain unclear. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs) comparing intensive with conventional glycaemic control in TBI requiring admission to an intensive care unit (ICU). METHODS:We systematically se...

journal_title：Critical care (London, England)

authors： Hermanides J,Plummer MP,Finnis M,Deane AM,Coles JP,Menon DK

更新日期：2018-01-19 00:00:00

abstract：:Climate change and environmental stewardship are phrases that have been defining the past few decades and promoting change in our societies. The sensitivities of intensive care as a specialty make the process of greening an intensive care unit a challenge, but not one that is insurmountable. This paper discusses oppor...

journal_title：Critical care (London, England)

authors： Chapman M,Chapman A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We sought to determine the effects of alternative resuscitation strategies on microcirculatory perfusion and examine any association between microcirculatory perfusion and mortality in sepsis. METHODS:This was a prospective, formally designed substudy of participants in the Protocolized Care in Early Septic...

journal_title：Critical care (London, England)

authors： Massey MJ,Hou PC,Filbin M,Wang H,Ngo L,Huang DT,Aird WC,Novack V,Trzeciak S,Yealy DM,Kellum JA,Angus DC,Shapiro NI,ProCESS investigators.

更新日期：2018-11-20 00:00:00

abstract：:Acid-base abnormalities are common in critically ill patients. Our ability to describe acid-base disorders must be precise. Small differences in corrections for anion gap, different types of analytical processes, and the basic approach used to diagnose acid-base aberrations can lead to markedly different interpretatio...

journal_title：Critical care (London, England)

authors： Gunnerson KJ

更新日期：2005-10-05 00:00:00

abstract：:The first part of this review addresses the diagnosis and differential diagnosis of the primary vasculitides Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa. Prompt diagnosis and treatment of these conditions ensures an optimal prognosis. The development of assays fo...

journal_title：Critical care (London, England)

authors： Semple D,Keogh J,Forni L,Venn R

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Anemia is a frequently encountered problem during inflammation. Hepcidin is an interleukin-6 (IL-6)-induced key modulator of inflammation-associated anemia. Human sepsis is a prototypical inflammatory syndrome, often complicated by the development of anemia. However, the association between inflammation, h...

journal_title：Critical care (London, England)

authors： van Eijk LT,Kroot JJ,Tromp M,van der Hoeven JG,Swinkels DW,Pickkers P

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Little is known about the development of acute lung injury outside the intensive care unit. We set out to document the following: the association between predefined clinical conditions and the development of acute lung injury by using the American-European consensus definition; the frequency of lung injury d...

journal_title：Critical care (London, England)

authors： Ferguson ND,Frutos-Vivar F,Esteban A,Gordo F,Honrubia T,Peñuelas O,Algora A,García G,Bustos A,Rodríguez I

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether using pharmacodynamic-based dosing of antimicrobials, such as extended/continuous infusions, in critically ill patients is associated with improved outcomes as compared with traditional dosing methods. METHODS:We searched Medline, HealthStar, EMBASE, Cochrane...

journal_title：Critical care (London, England)

authors： Chant C,Leung A,Friedrich JO

更新日期：2013-11-29 00:00:00

abstract：:This narrative review summarizes the role of vitamin C in mitigating oxidative injury-induced microcirculatory impairment and associated organ failure in ischemia/reperfusion or sepsis. Preclinical studies show that high-dose vitamin C can prevent or restore microcirculatory flow impairment by inhibiting activation of...

journal_title：Critical care (London, England)

authors： Oudemans-van Straaten HM,Spoelstra-de Man AM,de Waard MC

更新日期：2014-08-06 00:00:00

abstract：BACKGROUND:Kidney congestion is a common pathophysiologic pathway of acute kidney injury (AKI) in sepsis and heart failure. There is no noninvasive tool to measure kidney intracapsular pressure (KIP) directly. METHODS:We evaluated the correlation of KIP with kidney elasticity measured by ultrasound surface wave elasto...

journal_title：Critical care (London, England)

authors： Kashani KB,Mao SA,Safadi S,Amiot BP,Glorioso JM,Lieske JC,Nyberg SL,Zhang X

更新日期：2017-10-19 00:00:00

abstract：:The great majority of infections caused by the pandemic variant of the influenza virus (nvH1N1) are self-limited, but a small percentage of patients develop severe symptoms requiring hospitalization. Bermejo-Martin and colleagues have presented a pilot study describing the differences in the early immune response for ...

journal_title：Critical care (London, England)

authors： de Castro IF,Guzmán-Fulgencio M,García-Alvarez M,Resino S

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The analysis of flow and pressure waveforms generated by ventilators can be useful in the optimization of patient-ventilator interactions, notably in chronic obstructive pulmonary disease (COPD) patients. To date, however, a real clinical benefit of this approach has not been proven. METHODS:The aim of th...

journal_title：Critical care (London, England)

authors： Di Marco F,Centanni S,Bellone A,Messinesi G,Pesci A,Scala R,Perren A,Nava S

更新日期：2011-01-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) has a substantial mortality rate and annually affects more than 140,000 people in the USA alone. Standard management includes lung protective ventilation but this impairs carbon dioxide clearance and may lead to right heart dysfunction or increased intracranial pressure. Extr...

journal_title：Critical care (London, England)

authors： Cove ME,MacLaren G,Federspiel WJ,Kellum JA

更新日期：2012-09-21 00:00:00

abstract：:Thromboelastography and thromboelastometry represent viscoelastic diagnostic methodologies with promising application to diseases of altered coagulation. Their use in trauma-induced coagulopathy as a means of assessing the real-time status of the patient's functional coagulation profile in addition to its impact on ef...

journal_title：Critical care (London, England)

authors： Bluth MH,Kashuk JL

更新日期：2011-01-01 00:00:00