Clinical review: the meaning of acid-base abnormalities in the intensive care unit part I - epidemiology.

Abstract:

:Acid-base abnormalities are common in critically ill patients. Our ability to describe acid-base disorders must be precise. Small differences in corrections for anion gap, different types of analytical processes, and the basic approach used to diagnose acid-base aberrations can lead to markedly different interpretations and treatment strategies for the same disorder. By applying a quantitive acid-base approach, clinicians are able to account for small changes in ion distribution that may have gone unrecognized with traditional techniques of acid-base analysis. Outcome prediction based on the quantitative approach remains controversial. This is in part due to use of various technologies to measure acid-base variables, administration of fluid or medication that can alter acid-base results, and lack of standardized nomenclature. Without controlling for these factors it is difficult to appreciate the full effect that acid-base disorders have on patient outcomes, ultimately making results of outcome studies hard to compare.

journal_name

Crit Care

authors

Gunnerson KJ

doi

10.1186/cc3796

keywords:

subject

Has Abstract

pub_date

2005-10-05 00:00:00

pages

508-16

issue

5

eissn

1364-8535

issn

1466-609X

pii

cc3796

journal_volume

9

pub_type

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