Tracheal extubation and reintubation of the critically ill--challenges coming and going.


:Tracheal reintubation is a common event in critical care. Elmer and colleagues provide the first comparison of complication rates of initial and subsequent reintubation(s) during the same hospitalization. Their work shows an increased risk of complications associated with reintubation, in particular hypoxemia and hypotension, reminding us to be cautious with patients having minimal reserve and potentially altered airway anatomy. See related research by Elmer et al.,


Crit Care


Parotto M,Cooper RM




Has Abstract


2015-03-27 00:00:00












  • Hyperglycaemia in critically ill patients: marker or mediator of mortality?

    abstract::Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of h...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Corstjens AM,van der Horst IC,Zijlstra JG,Groeneveld AB,Zijlstra F,Tulleken JE,Ligtenberg JJ

    更新日期:2006-01-01 00:00:00

  • Long term effect of a medical emergency team on cardiac arrests in a teaching hospital.

    abstract:INTRODUCTION:It is unknown whether the reported short-term reduction in cardiac arrests associated with the introduction of the medical emergency team (MET) system can be sustained. METHOD:We conducted a prospective, controlled before-and-after examination of the effect of a MET system on the long-term incidence of ca...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Jones D,Bellomo R,Bates S,Warrillow S,Goldsmith D,Hart G,Opdam H,Gutteridge G

    更新日期:2005-01-01 00:00:00

  • Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study.

    abstract:INTRODUCTION:Authors of several studies have studied biomarkers and computed tomography (CT) findings in the acute phase after severe traumatic brain injury (TBI). However, the correlation between structural damage as assessed by neuroimaging and biomarkers has not been elucidated. The aim of this study was to investig...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Mondello S,Papa L,Buki A,Bullock MR,Czeiter E,Tortella FC,Wang KK,Hayes RL

    更新日期:2011-06-24 00:00:00

  • Respiratory support withdrawal in intensive care units: families, physicians and nurses views on two hypothetical clinical scenarios.

    abstract:INTRODUCTION:Evidence suggests that dying patients' physical and emotional suffering is inadequately treated in intensive care units. Although there are recommendations regarding decisions to forgo life-sustaining therapy, deciding on withdrawal of life support is difficult, and it is also difficult to decide who shoul...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Fumis RR,Deheinzelin D

    更新日期:2010-01-01 00:00:00

  • Blood glucose measurements in the critically ill: more than just a blood draw.

    abstract::A crucial determinant for the success of intensive insulin therapy in critically ill patients is the frequent and accurate measurement of blood glucose values with immediate feedback of results. In general, therefore, this is achieved by point-of-care testing, raising the question of the best way of monitoring blood g...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Brunkhorst FM,Wahl HG

    更新日期:2006-01-01 00:00:00

  • Noninvasive ventilation and the upper airway: should we pay more attention?

    abstract::In an effort to reduce the complications related to invasive ventilation, the use of noninvasive ventilation (NIV) has increased over the last years in patients with acute respiratory failure. However, failure rates for NIV remain high in specific patient categories. Several studies have identified factors that contri...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Oppersma E,Doorduin J,van der Heijden EH,van der Hoeven JG,Heunks LM

    更新日期:2013-12-05 00:00:00

  • How the relationships between general practitioners and intensivists can be improved: the general practitioners' point of view.

    abstract:INTRODUCTION:The present study assessed the opinion of general practitioners (GPs) concerning their relationships with intensivists. METHODS:An anonymous questionnaire was mailed to 7,239 GPs. GPs were asked about their professional activities, postgraduate intensive care unit (ICU) training, the rate of patient admit...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Etesse B,Jaber S,Mura T,Leone M,Constantin JM,Michelet P,Zoric L,Capdevila X,Malavielle F,Allaouchiche B,Orban JC,Fabbro-Peray P,Lefrant JY,AzuRéa Group.

    更新日期:2010-01-01 00:00:00

  • Alternative protocol to initiate high-frequency oscillatory ventilation: an experimental study.

    abstract:INTRODUCTION:The objective was to study the effects of a novel lung volume optimization procedure (LVOP) using high-frequency oscillatory ventilation (HFOV) upon gas exchange, the transpulmonary pressure (TPP), and hemodynamics in a porcine model of surfactant depletion. METHODS:With institutional review board approva...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Karmrodt J,David M,Yuan S,Markstaller K

    更新日期:2006-01-01 00:00:00

  • Erythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial.

    abstract:INTRODUCTION:Mortality and disability following ischemic stroke (IS) remains unacceptably high with respect to the conventional therapies. This study tested the effect of erythropoietin (EPO) on long-term neurological outcome in patients after acute IS. This study aimed to evaluate the safety and efficacy of two consec...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Tsai TH,Lu CH,Wallace CG,Chang WN,Chen SF,Huang CR,Tsai NW,Lan MY,Sung PH,Liu CF,Yip HK

    更新日期:2015-02-25 00:00:00

  • Central venous pressure measurement is associated with improved outcomes in septic patients: an analysis of the MIMIC-III database.

    abstract:PURPOSE:Measurement of central venous pressure (CVP) can be a useful clinical tool. However, the formal utility of CVP measurement in preventing mortality in septic patients has never been proven. METHODS:The Medical Information Mart for Intensive Care III (MIMIC-III) database was searched to identify septic patients ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Chen H,Zhu Z,Zhao C,Guo Y,Chen D,Wei Y,Jin J

    更新日期:2020-07-14 00:00:00

  • Imposed work of breathing during high-frequency oscillatory ventilation: a bench study.

    abstract:INTRODUCTION:The ventilator and the endotracheal tube impose additional workload in mechanically ventilated patients breathing spontaneously. The total work of breathing (WOB) includes elastic and resistive work. In a bench test we assessed the imposed WOB using 3100 A/3100 B SensorMedics high-frequency oscillatory ven...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: van Heerde M,van Genderingen HR,Leenhoven T,Roubik K,Plötz FB,Markhorst DG

    更新日期:2006-02-01 00:00:00

  • A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock.

    abstract:BACKGROUND:Septic shock (SS) and cardiogenic shock (CS) are two types of circulatory shock with a different etiology. Several studies have described the molecular alterations in SS patients, whereas the molecular factors involved in CS have been poorly investigated. We aimed to assess in the whole blood of CS and SS pa...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Braga D,Barcella M,Herpain A,Aletti F,Kistler EB,Bollen Pinto B,Bendjelid K,Barlassina C

    更新日期:2019-12-19 00:00:00

  • Safety and efficacy of noninvasive ventilation in patients with blunt chest trauma: a systematic review.

    abstract:INTRODUCTION:This systematic review looks at the use of noninvasive ventilation (NIV), inclusive of noninvasive positive pressure ventilation (NPPV) and continuous positive pressure ventilation (CPAP), in patients with chest trauma to determine its safety and clinical efficacy in patients with blunt chest trauma who ar...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Duggal A,Perez P,Golan E,Tremblay L,Sinuff T

    更新日期:2013-07-22 00:00:00

  • Daily urinary urea excretion to guide intermittent hemodialysis weaning in critically ill patients.

    abstract:BACKGROUND:There are no easily available markers of renal recovery to guide intermittent hemodialysis (IHD) weaning. The aim of this study was to identify markers for IHD weaning in critically ill patients with acute kidney injury (AKI). METHODS:We performed a retrospective single-center cohort study of patients treat...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Aniort J,Ait Hssain A,Pereira B,Coupez E,Pioche PA,Leroy C,Heng AE,Souweine B,Lautrette A

    更新日期:2016-02-19 00:00:00

  • Pituitary-adrenal function in patients with acute subarachnoid haemorrhage: a prospective cohort study.

    abstract:INTRODUCTION:Subarachnoid haemorrhage (SAH) may damage the hypothalamo-pituitary-adrenal gland (HPA) axis and disturb cortisol metabolism. There are no available data that relates to the response of the HPA axis in the acute phase of SAH. We aimed to characterise the behavior of serum adrenocorticotropic hormone (ACTH)...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Bendel S,Koivisto T,Ruokonen E,Rinne J,Romppanen J,Vauhkonen I,Kiviniemi V,Uusaro A

    更新日期:2008-01-01 00:00:00

  • In-vivo validation of a new non-invasive continuous ventricular stroke volume monitoring system in an animal model.

    abstract:INTRODUCTION:Recently, a non-invasive, continuous ventricular stroke volume monitoring system using skin electrodes has been developed. In contrast to impedance-based methods, the new technique (ventricular field recognition) enables measurement of changes in ventricular volume. A prototype using this new method was bu...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Konings MK,Grundeman PF,Goovaerts HG,Roosendaal MR,Hoefer IE,Doevendans PA,Rademakers FE,Buhre WF

    更新日期:2011-07-11 00:00:00

  • B-type natriuretic peptide release and left ventricular filling pressure assessed by echocardiographic study after subarachnoid hemorrhage: a prospective study in non-cardiac patients.

    abstract:INTRODUCTION:Serum B-type natriuretic peptide (BNP) is frequently elevated after subarachnoid hemorrhage (SAH), but whether this high BNP level is related to transient elevation of left ventricular filling pressure (LVFP) is unknown. However, in patients with preexistent cardiac pathologies, it is impossible to differe...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Meaudre E,Jego C,Kenane N,Montcriol A,Boret H,Goutorbe P,Habib G,Palmier B

    更新日期:2009-01-01 00:00:00

  • Impact of a computerized decision support tool deployed in two intensive care units on acute kidney injury progression and guideline compliance: a prospective observational study.

    abstract:BACKGROUND:Acute kidney injury (AKI) affects a large proportion of the critically ill and is associated with worse patient outcomes. Early identification of AKI can lead to earlier initiation of supportive therapy and better management. In this study, we evaluate the impact of computerized AKI decision support tool int...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Bourdeaux C,Ghosh E,Atallah L,Palanisamy K,Patel P,Thomas M,Gould T,Warburton J,Rivers J,Hadfield J

    更新日期:2020-11-23 00:00:00

  • Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death.

    abstract:BACKGROUND:Acute kidney injury (AKI) is common among intensive care unit (ICU) patients. AKI is highly heterogeneous, with variable links to poor outcomes. Current approaches to classify AKI severity and identify patients at highest risk for poor outcomes focus on the maximum change in serum creatinine (SCr) values. Ho...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Bhatraju PK,Mukherjee P,Robinson-Cohen C,O'Keefe GE,Frank AJ,Christie JD,Meyer NJ,Liu KD,Matthay MA,Calfee CS,Christiani DC,Himmelfarb J,Wurfel MM

    更新日期:2016-11-17 00:00:00

  • Correction to: Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study.

    abstract::In the publication of this article [1], there are 4 collaborating authors missing from the 'MARS consortium'. This has now been included in this correction article. ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,已发布勘误


    authors: Klein Klouwenberg PMC,Spitoni C,van der Poll T,Bonten MJ,Cremer OL,MARS consortium.

    更新日期:2020-02-06 00:00:00

  • Prehospital point of care testing of blood gases and electrolytes - an evaluation of IRMA.

    abstract::BACKGROUND: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. RESULTS: A portable, battery-powered blood analyzer was used on patients in life threatening conditions to determine pH, pCO2, pO2, sodium, potassium and ionized c...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Prause G,Ratzenhofer-Komenda B,Offner A,Lauda P,Voit H,Pojer H

    更新日期:1997-01-01 00:00:00

  • Epidemiology of critically ill patients in intensive care units: a population-based observational study.

    abstract:INTRODUCTION:Epidemiologic assessment of critically ill people in Intensive Care Units (ICUs) is needed to ensure the health care system can meet current and future needs. However, few such studies have been published. METHODS:Population-based analysis of all adult ICU care in the Canadian province of Manitoba, 1999 t...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Garland A,Olafson K,Ramsey CD,Yogendran M,Fransoo R

    更新日期:2013-09-30 00:00:00

  • A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes.

    abstract:INTRODUCTION:Critical illness is commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycaemia, but not all severely ill develop hyperglycemia and some do even in mild disease. We hypothesised that acute disease only ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Gornik I,Vujaklija-Brajkovic A,Renar IP,Gasparovic V

    更新日期:2010-01-01 00:00:00

  • Medical emergencies on board commercial airlines: is documentation as expected?

    abstract:INTRODUCTION:The purpose of this study was to perform a descriptive, content-based analysis on the different forms of documentation for in-flight medical emergencies that are currently provided in the emergency medical kits on board commercial airlines. METHODS:Passenger airlines in the World Airline Directory were co...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Sand M,Morrosch S,Sand D,Altmeyer P,Bechara FG

    更新日期:2012-12-12 00:00:00

  • Metformin-associated lactic acidosis in an intensive care unit.

    abstract:INTRODUCTION:Metformin-associated lactic acidosis (MALA) is a classic side effect of metformin and is known to be a severe disease with a high mortality rate. The treatment of MALA with dialysis is controversial and is the subject of many case reports in the literature. We aimed to assess the prevalence of MALA in a 16...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Peters N,Jay N,Barraud D,Cravoisy A,Nace L,Bollaert PE,Gibot S

    更新日期:2008-01-01 00:00:00

  • A positive fluid balance is an independent prognostic factor in patients with sepsis.

    abstract:INTRODUCTION:Intravenous fluid administration is an essential component of sepsis management, but a positive fluid balance has been associated with worse prognosis. We analyzed whether a positive fluid balance and its persistence over time was an independent prognostic factor in septic patients. METHODS:We prospective...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Acheampong A,Vincent JL

    更新日期:2015-06-15 00:00:00

  • Point accuracy and reliability of an interstitial continuous glucose-monitoring device in critically ill patients: a prospective study.

    abstract:INTRODUCTION:There is a need for continuous glucose monitoring in critically ill patients. The objective of this trial was to determine the point accuracy and reliability of a device designed for continuous monitoring of interstitial glucose levels in intensive care unit patients. METHODS:We evaluated point accuracy b...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: van Hooijdonk RT,Leopold JH,Winters T,Binnekade JM,Juffermans NP,Horn J,Fischer JC,van Dongen-Lases EC,Schultz MJ

    更新日期:2015-02-05 00:00:00

  • Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials.

    abstract:INTRODUCTION:Due to resource limitations, few critical care interventions have been rigorously evaluated with adequately powered randomized clinical trials (RCTs). There is a need to improve the efficiency of RCTs in critical care so that more definitive high quality RCTs can be completed with the available resources. ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Heyland DK,Muscedere J,Drover J,Jiang X,Day AG,Canadian Critical Care Trials Group.

    更新日期:2011-01-01 00:00:00

  • Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China.

    abstract:BACKGROUND:In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. METHODS:Retrospective case series of COVID-19 patien...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Wang D,Yin Y,Hu C,Liu X,Zhang X,Zhou S,Jian M,Xu H,Prowle J,Hu B,Li Y,Peng Z

    更新日期:2020-04-30 00:00:00

  • Blocking IL-1 to prevent respiratory failure in COVID-19.

    abstract::COVID-19 is an emerging disease that can manifest itself as asymptomatic or mild respiratory tract infection in the majority of individuals, but in some, it can progress into severe pneumonia and acute respiratory distress syndrome (ARDS). Inflammation is known to play a crucial role in the pathogenesis of severe infe...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: van de Veerdonk FL,Netea MG

    更新日期:2020-07-18 00:00:00