Rapid response systems: are they really effective?


:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.


Crit Care


Sandroni C,D'Arrigo S,Antonelli M




Has Abstract


2015-03-16 00:00:00












  • Alarms in the intensive care unit: how can the number of false alarms be reduced?

    abstract::Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms. This paper gives an overview of the problems related to their current design and the objectives of monitoring. The current approaches used to improve the s...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Chambrin MC

    更新日期:2001-08-01 00:00:00

  • Dosing adjuvant vitamin C in critically ill patients undergoing continuous renal replacement therapy: We are not there yet!

    abstract:: ...

    journal_title:Critical care (London, England)

    pub_type: 评论,信件


    authors: Honore PM,De Bels D,Kugener L,Redant S,Attou R,Gallerani A,Spapen HD

    更新日期:2019-01-09 00:00:00

  • Tracheal extubation and reintubation of the critically ill--challenges coming and going.

    abstract::Tracheal reintubation is a common event in critical care. Elmer and colleagues provide the first comparison of complication rates of initial and subsequent reintubation(s) during the same hospitalization. Their work shows an increased risk of complications associated with reintubation, in particular hypoxemia and hypo...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Parotto M,Cooper RM

    更新日期:2015-03-27 00:00:00

  • Blood glucose measurements in the critically ill: more than just a blood draw.

    abstract::A crucial determinant for the success of intensive insulin therapy in critically ill patients is the frequent and accurate measurement of blood glucose values with immediate feedback of results. In general, therefore, this is achieved by point-of-care testing, raising the question of the best way of monitoring blood g...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Brunkhorst FM,Wahl HG

    更新日期:2006-01-01 00:00:00

  • Effect of bladder volume on measured intravesical pressure: a prospective cohort study.

    abstract:INTRODUCTION:Correct bedside measurement of intra-abdominal pressure (IAP) is important. The bladder method is considered as the gold standard for indirect IAP measurement, but the instillation volumes reported in the literature vary substantially. The aim of this study was to evaluate the effect of instillation volume...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Malbrain ML,Deeren DH

    更新日期:2006-01-01 00:00:00

  • Open the intensive care unit doors to HIV-infected patients with sepsis.

    abstract::Severe sepsis is more and more frequent, especially because of an increased rate of immunocompromised patients. Despite the improvement in the overall prognosis of HIV/AIDS patients and the improvement of global ICU care, the prognosis of HIV/ADS patients hospitalized in ICU with severe sepsis remained poor. This situ...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Timsit JF

    更新日期:2005-01-01 00:00:00

  • Pituitary-adrenal function in patients with acute subarachnoid haemorrhage: a prospective cohort study.

    abstract:INTRODUCTION:Subarachnoid haemorrhage (SAH) may damage the hypothalamo-pituitary-adrenal gland (HPA) axis and disturb cortisol metabolism. There are no available data that relates to the response of the HPA axis in the acute phase of SAH. We aimed to characterise the behavior of serum adrenocorticotropic hormone (ACTH)...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Bendel S,Koivisto T,Ruokonen E,Rinne J,Romppanen J,Vauhkonen I,Kiviniemi V,Uusaro A

    更新日期:2008-01-01 00:00:00

  • The 21st International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 20-23 March 2001.

    abstract::The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The promise of extracorporeal liver replacement therapy and noninvasive ventilation were other areas of interest. Ethical issues als...

    journal_title:Critical care (London, England)



    authors: Ball J,Venn R

    更新日期:2001-01-01 00:00:00

  • Omega-3 fatty acid-containing parenteral nutrition in ICU patients: systematic review with meta-analysis and cost-effectiveness analysis.

    abstract:BACKGROUND:Omega-3 (ω-3) fatty acid (FA)-containing parenteral nutrition (PN) is associated with significant improvements in patient outcomes compared with standard PN regimens without ω-3 FA lipid emulsions. Here, we evaluate the impact of ω-3 FA-containing PN versus standard PN on clinical outcomes and costs in adult...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Pradelli L,Klek S,Mayer K,Omar Alsaleh AJ,Rosenthal MD,Heller AR,Muscaritoli M

    更新日期:2020-11-03 00:00:00

  • Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study.

    abstract:INTRODUCTION:Recombinant human activated protein C (rhAPC) is the first drug for which a reduction of mortality in severe sepsis has been demonstrated. However, the mechanism by which this reduction in mortality is achieved is still not clearly defined. The aim of the present study was to evaluate the dynamics of the a...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: de Pont AC,Bakhtiari K,Hutten BA,de Jonge E,Vroom MB,Meijers JC,Büller HR,Levi M

    更新日期:2005-10-05 00:00:00

  • Endotoxemia and mortality prediction in ICU and other settings: underlying risk and co-detection of gram negative bacteremia are confounders.

    abstract:INTRODUCTION:The interdependence between endotoxemia, gram negative (GN) bacteremia and mortality has been extensively studied. Underlying patient risk and GN bacteremia types are possible confounders of the relationship. METHODS:Published studies with ≥ 10 patients in either ICU or non-ICU settings, endotoxemia detec...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Hurley JC,Guidet B,Offenstadt G,Maury E

    更新日期:2012-08-07 00:00:00

  • Forced oscillation assessment of respiratory mechanics in ventilated patients.

    abstract::The forced oscillation technique (FOT) is a method for non-invasively assessing respiratory mechanics that is applicable both in paralysed and non-paralysed patients. As the FOT requires a minimal modification of the conventional ventilation setting and does not interfere with the ventilation protocol, the technique i...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Navajas D,Farré R

    更新日期:2001-01-01 00:00:00

  • Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based review.

    abstract::Multiple studies have addressed deep vein thrombosis chemoprophylaxis timing in traumatic brain injuries. However, a precise time for safe and effective chemoprophylaxis is uncertain according to experts. A comprehensive literature review on brain injuries was performed to delineate temporal proportions for 1) spontan...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Abdel-Aziz H,Dunham CM,Malik RJ,Hileman BM

    更新日期:2015-03-24 00:00:00

  • Managing daily intensive care activities: an observational study concerning ad hoc decision making of charge nurses and intensivists.

    abstract:INTRODUCTION:Management of daily activities in ICUs is challenging. ICU shift leaders, charge nurses and intensivists have to make several immediate ad hoc decisions to enable the fluent flow of ICU activities. Even though the management of ICU activities is quite well delineated by international consensus guidelines, ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Lundgrén-Laine H,Kontio E,Perttilä J,Korvenranta H,Forsström J,Salanterä S

    更新日期:2011-08-08 00:00:00

  • Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial.

    abstract:BACKGROUND:There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen concentrate, which may have advantages of more rapid administrati...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Curry N,Foley C,Wong H,Mora A,Curnow E,Zarankaite A,Hodge R,Hopkins V,Deary A,Ray J,Moss P,Reed MJ,Kellett S,Davenport R,Stanworth S

    更新日期:2018-06-18 00:00:00

  • Common variants of NFE2L2 gene predisposes to acute respiratory distress syndrome in patients with severe sepsis.

    abstract:INTRODUCTION:The purpose of this study was to investigate whether common variants across the nuclear factor erythroid 2-like 2 (NFE2L2) gene contribute to the development of the acute respiratory distress syndrome (ARDS) in patients with severe sepsis. NFE2L2 is involved in the response to oxidative stress, and it has ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Acosta-Herrera M,Pino-Yanes M,Blanco J,Ballesteros JC,Ambrós A,Corrales A,Gandía F,Subirá C,Domínguez D,Baluja A,Añón JM,Adalia R,Pérez-Méndez L,Flores C,Villar J,GRECIA and GEN-SEP networks.

    更新日期:2015-06-16 00:00:00

  • Use of noninvasive ventilation in immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis.

    abstract:BACKGROUND:Acute respiratory failure (ARF) remains a common hazardous complication in immunocompromised patients and is associated with increased mortality rates when endotracheal intubation is needed. We aimed to evaluate the effect of early noninvasive ventilation (NIV) compared with oxygen therapy alone in this pati...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析,评审


    authors: Huang HB,Xu B,Liu GY,Lin JD,Du B

    更新日期:2017-01-07 00:00:00

  • Extracorporeal membrane oxygenation for severe acute respiratory failure.

    abstract::Extracorporeal membrane oxygenation (ECMO) is a technique for providing life support, in case the natural lungs are failing and are not able to maintain a sufficient oxygenation of the body's organ systems. ECMO technique was an adaptation of conventional cardiopulmonary bypass techniques and introduced into treatment...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Lewandowski K

    更新日期:2000-01-01 00:00:00

  • Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study.

    abstract:INTRODUCTION:Anemia is a frequently encountered problem during inflammation. Hepcidin is an interleukin-6 (IL-6)-induced key modulator of inflammation-associated anemia. Human sepsis is a prototypical inflammatory syndrome, often complicated by the development of anemia. However, the association between inflammation, h...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: van Eijk LT,Kroot JJ,Tromp M,van der Hoeven JG,Swinkels DW,Pickkers P

    更新日期:2011-01-01 00:00:00

  • A week seems to be weak: tailoring duration of antibiotic treatment in Gram-negative ventilator-associated pneumonia.

    abstract::The optimal length of antimicrobial therapy has not been extensively studied for a great majority of infections and, in critically ill patients affected by ventilator-associated pneumonia, is a persisting and unsolved issue confronting clinicians. The integration of biomarkers, clinical judgment, and microbiologic era...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Martin-Loeches I,Torres A

    更新日期:2013-01-21 00:00:00

  • Changes in stroke volume induced by passive leg raising in spontaneously breathing patients: comparison between echocardiography and Vigileo/FloTrac device.

    abstract:INTRODUCTION:Passive leg raising (PLR) is a simple reversible maneuver that mimics rapid fluid loading and increases cardiac preload. The effects of this endogenous volume expansion on stroke volume enable the testing of fluid responsiveness with accuracy in spontaneously breathing patients. However, this maneuver requ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Biais M,Vidil L,Sarrabay P,Cottenceau V,Revel P,Sztark F

    更新日期:2009-01-01 00:00:00

  • Clinical review: Serious adverse events associated with the use of rituximab - a critical care perspective.

    abstract::The advent of biologic agents has provided a more specific and targeted approach to the treatment of various hematological malignancies and other autoimmune disorders. Such biologic agents have been relatively well tolerated with fewer adverse events reported as compared with many other chemotherapeutic agents. Rituxi...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Kasi PM,Tawbi HA,Oddis CV,Kulkarni HS

    更新日期:2012-08-31 00:00:00

  • Colonization pressure: a critical parameter in the epidemiology of antibiotic-resistant bacteria.

    abstract::The recognition of colonization pressure as an important risk factor for acquisition of antibiotic-resistant bacteria in the ICU, including Acinetobacter species, has major consequences for our understanding of risk factor analyses. Moreover, the importance of colonization pressure underpins the role of cross-transmis...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Bonten MJ

    更新日期:2012-07-31 00:00:00

  • Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.

    abstract:BACKGROUND:Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARD...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Boyle AJ,Madotto F,Laffey JG,Bellani G,Pham T,Pesenti A,Thompson BT,O'Kane CM,Deane AM,McAuley DF,LUNG SAFE Investigators.,ESICM Trials Group.

    更新日期:2018-10-27 00:00:00

  • Variation in the PaO2/FiO2 ratio with FiO2: mathematical and experimental description, and clinical relevance.

    abstract:INTRODUCTION:Previous studies have shown through theoretical analyses that the ratio of the partial pressure of oxygen in arterial blood (PaO2) to the inspired oxygen fraction (FiO2) varies with the FiO2 level. The aim of the present study was to evaluate the relevance of this variation both theoretically and experimen...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Karbing DS,Kjaergaard S,Smith BW,Espersen K,Allerød C,Andreassen S,Rees SE

    更新日期:2007-01-01 00:00:00

  • Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial.

    abstract:BACKGROUND:Severe traumatic brain injury (TBI) has been increasing with greater incidence of injuries from traffic or sporting accidents. Although there are a number of animal models of TBI using progesterone for head injury, the effects of progesterone on neurologic outcome of acute TBI patients remain unclear. The ai...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Xiao G,Wei J,Yan W,Wang W,Lu Z

    更新日期:2008-01-01 00:00:00

  • Infections of respiratory or abdominal origin in ICU patients: what are the differences?

    abstract:INTRODUCTION:There are few data related to the effects of different sources of infection on outcome. We used the Sepsis Occurrence in Acutely ill Patients (SOAP) database to investigate differences in the impact of respiratory tract and abdominal sites of infection on organ failure and survival. METHODS:The SOAP study...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Volakli E,Spies C,Michalopoulos A,Groeneveld AB,Sakr Y,Vincent JL

    更新日期:2010-01-01 00:00:00

  • The incretin effect in critically ill patients: a case-control study.

    abstract:INTRODUCTION:Patients admitted to the intensive care unit often develop hyperglycaemia, but the underlying mechanisms have not been fully described. The incretin effect is reduced in patients with type 2 diabetes. Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resis...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Nielsen ST,Janum S,Krogh-Madsen R,Solomon TP,Møller K

    更新日期:2015-11-16 00:00:00

  • Prevalence of burnout among intensivists in mainland China: a nationwide cross-sectional survey.

    abstract:BACKGROUND:Burnout has gained increasing attention worldwide; however, there is a lack of relevant research in China. This study investigated the prevalence and factors associated with burnout in physicians of the intensive care unit (ICU) in mainland China. METHODS:This cross-sectional multicenter study included crit...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Wang J,Hu B,Peng Z,Song H,Cai S,Rao X,Li L,Li J

    更新日期:2021-01-05 00:00:00

  • Hyperbilirubinaemia after major thoracic surgery: comparison between open-heart surgery and oesophagectomy.

    abstract:BACKGROUND:Hyperbilirubinaemia is a common occurrence in patients who are admitted to intensive care units (ICUs) after major surgery, and it is associated with high mortality. We investigated the incidence of hyperbilirubinaemia after two major types of thoracic surgery: open-heart surgery and oesophagectomy. In order...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Hosotsubo KK,Nishimura M,Nishimura S

    更新日期:2000-01-01 00:00:00