Alarms in the intensive care unit: how can the number of false alarms be reduced?


:Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms. This paper gives an overview of the problems related to their current design and the objectives of monitoring. The current approaches used to improve the situation are then presented from two main standpoints: organizational and behavioural on the one hand, and technical on the other.


Crit Care


Chambrin MC





Has Abstract


2001-08-01 00:00:00












  • Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study.

    abstract:INTRODUCTION:Blood transfusion in the perioperative period has frequently been associated with an excess of nosocomial infections. Whilst transfused whole blood induces specific host immune alteration that may predispose to nosocomial infections, the immunomodulating properties associated with leukodepleted blood remai...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Fragkou PC,Torrance HD,Pearse RM,Ackland GL,Prowle JR,Owen HC,Hinds CJ,O'Dwyer MJ

    更新日期:2014-10-01 00:00:00

  • Usefulness of N-terminal pro-brain natriuretic peptide and C-reactive protein to predict ICU mortality in unselected medical ICU patients: a prospective, observational study.

    abstract:INTRODUCTION:The performance of N-terminal pro-brain natriuretic peptide (NT-proBNP) and C-reactive protein (CRP) to predict clinical outcomes in ICU patients is unimpressive. We aimed to assess the prognostic value of NT-proBNP, CRP or the combination of both in unselected medical ICU patients. METHODS:A total of 576...

    journal_title:Critical care (London, England)

    pub_type: 临床试验,杂志文章


    authors: Wang F,Pan W,Pan S,Wang S,Ge Q,Ge J

    更新日期:2011-01-01 00:00:00

  • Hyperoncotic colloids and acute kidney injury: a meta-analysis of randomized trials.

    abstract:INTRODUCTION:It has been hypothesized that hyperoncotic colloids might contribute to acute kidney injury (AKI). However, the validity of this hypothesis remains unclear. METHODS:A meta-analysis was conducted of randomized controlled trials evaluating AKI after infusion of hyperoncotic albumin and hydroxyethyl starch (...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析


    authors: Wiedermann CJ,Dunzendorfer S,Gaioni LU,Zaraca F,Joannidis M

    更新日期:2010-01-01 00:00:00

  • Recently published papers: from superbugs to superbowl.

    abstract::Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular re...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Tomlinson LA,Forni LG

    更新日期:2005-04-01 00:00:00

  • The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest.

    abstract:INTRODUCTION:Patients after out-of-hospital cardiac arrest (OHCA) benefit from therapeutic hypothermia for 24 hours. The time needed to reach hypothermia (target temperature of 32 degrees C to 34 degrees C) varies widely. In this study, we explore the relation between measures of body composition and the time needed to...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Jimmink JJ,Binnekade JM,Paulus F,Mathus-Vliegen EM,Schultz MJ,Vroom MB

    更新日期:2008-01-01 00:00:00

  • Effects of selective β1-adrenoceptor blockade on cardiovascular and renal function and circulating cytokines in ovine hyperdynamic sepsis.

    abstract:INTRODUCTION:Activation of the sympathetic nervous system has beneficial cardiovascular effects in sepsis, but there is also evidence that sympatholytics have beneficial actions in sepsis. We therefore determined the effect of selective β1-adrenoceptor blockade on cardiac and renal function and cytokine release in ovin...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Calzavacca P,Lankadeva YR,Bailey SR,Bailey M,Bellomo R,May CN

    更新日期:2014-11-21 00:00:00

  • The subxiphoid view cannot replace the apical view for transthoracic echocardiographic assessment of hemodynamic status.

    abstract:INTRODUCTION:This prospective study aimed to assess whether use of the subxiphoid acoustic window in transthoracic echocardiography (TTE) can be an accurate alternative in the absence of an apical view to assess hemodynamic parameters. METHODS:This prospective study took place in a teaching hospital medical ICU. Over ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Maizel J,Salhi A,Tribouilloy C,Massy ZA,Choukroun G,Slama M

    更新日期:2013-09-03 00:00:00

  • Intensive insulin treatment improves forearm blood flow in critically ill patients: a randomized parallel design clinical trial.

    abstract:INTRODUCTION:Intensive insulin treatment of critically ill patients was seen as a promising method of treatment, though recent studies showed that reducing the blood glucose level below 6 mmol/l had a detrimental outcome. The mechanisms of the effects of insulin in the critically ill are not completely understood. The ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Žuran I,Poredos P,Skale R,Voga G,Gabrscek L,Pareznik R

    更新日期:2009-01-01 00:00:00

  • Beyond volutrauma in ARDS: the critical role of lung tissue deformation.

    abstract::Ventilator-induced lung injury (VILI) consists of tissue damage and a biological response resulting from the application of inappropriate mechanical forces to the lung parenchyma. The current paradigm attributes VILI to overstretching due to very high-volume ventilation (volutrauma) and cyclic changes in aeration due ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Albaiceta GM,Blanch L

    更新日期:2011-04-07 00:00:00

  • Rapid response systems: are they really effective?

    abstract::This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at Further information about the Annual Update in Intensive Care a...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Sandroni C,D'Arrigo S,Antonelli M

    更新日期:2015-03-16 00:00:00

  • Cardiac force-frequency relationship and frequency-dependent acceleration of relaxation are impaired in LPS-treated rats.

    abstract:INTRODUCTION:Frequency-dependent acceleration of relaxation (FDAR) ensures appropriate ventricular filling at high heart rates and results from accelerated sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) activity independent of calcium removal from the cell. Because lipopolysaccharide (LPS) challenge may indu...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Joulin O,Marechaux S,Hassoun S,Montaigne D,Lancel S,Neviere R

    更新日期:2009-01-01 00:00:00

  • Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses.

    abstract:BACKGROUND:Crystalloids and different component colloids, used for volume resuscitation, are sometimes associated with various adverse effects. Clinical trial findings for such fluid types in different patients' conditions are conflicting. Whether the mortality benefit of balanced crystalloid than saline can be inferre...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Tseng CH,Chen TT,Wu MY,Chan MC,Shih MC,Tu YK

    更新日期:2020-12-14 00:00:00

  • Associations between single nucleotide polymorphisms in the FAS pathway and acute kidney injury.

    abstract:INTRODUCTION:To determine whether single nucleotide polymorphisms (SNPs) in FAS and related genes are associated with acute kidney injury (AKI) in patients with acute respiratory distress syndrome (ARDS). METHODS:We studied 401 (Caucasian N = 310 and African-American N = 91) patients aged ≥ 13 years with ALI who enrol...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Bhatraju P,Hsu C,Mukherjee P,Glavan BJ,Burt A,Mikacenic C,Himmelfarb J,Wurfel M

    更新日期:2015-10-19 00:00:00

  • Nutrition of the COVID-19 patient in the intensive care unit (ICU): a practical guidance.

    abstract::Five to 10% of the coronavirus SARS-CoV-2-infected patients, i.e., with new coronavirus disease 2019 (COVID-19), are presenting with an acute respiratory distress syndrome (ARDS) requiring urgent respiratory and hemodynamic support in the intensive care unit (ICU). However, nutrition is an important element of care. T...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Thibault R,Seguin P,Tamion F,Pichard C,Singer P

    更新日期:2020-07-19 00:00:00

  • Association between hospital volume and network membership and an analgesia, sedation and delirium order set quality score: a cohort study.

    abstract:INTRODUCTION:Protocols for the delivery of analgesia, sedation and delirium care of the critically ill, mechanically ventilated patient have been shown to improve outcomes but are not uniformly used. The extent to which elements of analgesia, sedation and delirium guidelines are incorporated into order sets at hospital...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Dale CR,Hayden SJ,Treggiari MM,Curtis JR,Seymour CW,Yanez ND 3rd,Fan VS

    更新日期:2012-06-18 00:00:00

  • Complex systems and the technology of variability analysis.

    abstract::Characteristic patterns of variation over time, namely rhythms, represent a defining feature of complex systems, one that is synonymous with life. Despite the intrinsic dynamic, interdependent and nonlinear relationships of their parts, complex biological systems exhibit robust systemic stability. Applied to critical ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Seely AJ,Macklem PT

    更新日期:2004-12-01 00:00:00

  • Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial.

    abstract:INTRODUCTION:Experimental research has demonstrated that the level of neuroprotection conferred by the various barbiturates is not equal. Until now no controlled studies have been conducted to compare their effectiveness, even though the Brain Trauma Foundation Guidelines recommend that such studies be undertaken. The ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Pérez-Bárcena J,Llompart-Pou JA,Homar J,Abadal JM,Raurich JM,Frontera G,Brell M,Ibáñez J,Ibáñez J

    更新日期:2008-01-01 00:00:00

  • DHEA-dependent and organ-specific regulation of TNF-alpha mRNA expression in a murine polymicrobial sepsis and trauma model.

    abstract:INTRODUCTION:Dehydroepiandrosterone (DHEA) improves survival after trauma and sepsis, while mechanisms of action are not yet fully understood. Therefore, we investigated the influence of DHEA on local cytokine expression in a two-hit model. METHODS:Male NMRI mice were subjected to femur fracture/hemorrhagic shock and ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Barkhausen T,Hildebrand F,Krettek C,van Griensven M

    更新日期:2009-01-01 00:00:00

  • Effect of glomerular filtration rate impairment on diagnostic performance of neutrophil gelatinase-associated lipocalin and B-type natriuretic peptide as markers of acute cardiac and renal failure in chronic kidney disease patients.

    abstract:INTRODUCTION:Cardio-renal syndromes are characterized by the impairment of cardiac and renal functions. Plasma and urinary neutrophil gelatinase-associated lipocalin (NGAL), and plasma B-type natriuretic peptide (BNP) are markers of acute kidney injury (AKI) and heart failure (HF), respectively. METHODS:GFR (99mTc-DTP...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Donadio C

    更新日期:2014-02-28 00:00:00

  • Use of ultrasound guidance to improve the safety of percutaneous dilatational tracheostomy: a literature review.

    abstract::Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Alansari M,Alotair H,Al Aseri Z,Elhoseny MA

    更新日期:2015-05-18 00:00:00

  • Functional evaluation of sublingual microcirculation indicates successful weaning from VA-ECMO in cardiogenic shock.

    abstract:BACKGROUND:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Akin S,Dos Reis Miranda D,Caliskan K,Soliman OI,Guven G,Struijs A,van Thiel RJ,Jewbali LS,Lima A,Gommers D,Zijlstra F,Ince C

    更新日期:2017-10-26 00:00:00

  • Does pulse pressure variation predict fluid responsiveness in critically ill patients? A systematic review and meta-analysis.

    abstract:INTRODUCTION:Fluid resuscitation is crucial in managing hemodynamically unstable patients. The last decade witnessed the use of pulse pressure variation (PPV) to predict fluid responsiveness. However, as far as we know, no systematic review and meta-analysis has been carried out to evaluate the value of PPV in predicti...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析,评审


    authors: Yang X,Du B

    更新日期:2014-11-27 00:00:00

  • Pulse contour analysis: is it able to reliably detect changes in cardiac output in the haemodynamically unstable patient?

    abstract::Three pulse contour systems for monitoring cardiac output - LiDCO Plus™, PiCCO Plus™ and FloTrac™ - were compared in postcardiac surgery patients. None of the three methods demonstrated good trending ability according to concordance analysis. Pulse contour systems remain unreliable in the haemodynamically unstable pat...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Critchley LA

    更新日期:2011-01-19 00:00:00

  • Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia.

    abstract::Despite progress in the diagnosis, prevention and therapy for hospital-acquired infections, ventilator-associated pneumonia (VAP) continues to complicate the course of a significant proportion of patients receiving mechanical ventilation. Mortality rates among patients with VAP have been reported to be as high as 72%,...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Rello J

    更新日期:2005-06-01 00:00:00

  • Decreased CX3CR1 messenger RNA expression is an independent molecular biomarker of early and late mortality in critically ill patients.

    abstract:BACKGROUND:Chemokine (C-X3-C motif) receptor 1 (CX3CR1) was identified as the most differentially expressed gene between survivors and non-survivors in two independent cohorts of septic shock patients and was proposed as a marker of sepsis-induced immunosuppression. Whether such a biomarker is associated with mortality...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Friggeri A,Cazalis MA,Pachot A,Cour M,Argaud L,Allaouchiche B,Floccard B,Schmitt Z,Martin O,Rimmelé T,Fontaine-Kesteloot O,Page M,Piriou V,Bohé J,Monneret G,Morisset S,Textoris J,Vallin H,Blein S,Maucort-Boulch D,

    更新日期:2016-06-30 00:00:00

  • High protein intake during the early phase of critical illness: yes or no?

    abstract::The rationale for the provision of nitrogen from proteins given via the enteral route or from intravenous amino acids is to boost the synthesis of muscle proteins, and thereby to limit the severity of intensive care unit-acquired weakness by the prevention of muscle loss. However, the optimal timing for supplemental n...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Preiser JC

    更新日期:2018-10-25 00:00:00

  • Influence of different electrode belt positions on electrical impedance tomography imaging of regional ventilation: a prospective observational study.

    abstract:BACKGROUND:Electrical impedance tomography (EIT) is a non-invasive bedside tool which allows an individualized ventilator strategy by monitoring tidal ventilation and lung aeration. EIT can be performed at different cranio-caudal thoracic levels, but data are missing about the optimal belt position. The main goal of th...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Karsten J,Stueber T,Voigt N,Teschner E,Heinze H

    更新日期:2016-01-08 00:00:00

  • Colonization pressure: a critical parameter in the epidemiology of antibiotic-resistant bacteria.

    abstract::The recognition of colonization pressure as an important risk factor for acquisition of antibiotic-resistant bacteria in the ICU, including Acinetobacter species, has major consequences for our understanding of risk factor analyses. Moreover, the importance of colonization pressure underpins the role of cross-transmis...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Bonten MJ

    更新日期:2012-07-31 00:00:00

  • Intraoperative renal near-infrared spectroscopy indicates developing acute kidney injury in infants undergoing cardiac surgery with cardiopulmonary bypass: a case-control study.

    abstract:INTRODUCTION:Acute kidney injury (AKI) is a frequent complication after cardiac surgery with cardiopulmonary bypass in infants. Renal near-infrared spectroscopy (NIRS) is used to evaluate regional oximetry in a non-invasive continuous real-time fashion, and reflects tissue perfusion. The aim of this study was to evalua...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Ruf B,Bonelli V,Balling G,Hörer J,Nagdyman N,Braun SL,Ewert P,Reiter K

    更新日期:2015-01-29 00:00:00

  • Vasopressin in vasodilatory shock: hemodynamic stabilization at the cost of the liver and the kidney?

    abstract::Infusing arginine vasopressin (AVP) in advanced vasodilatory shock is usually accompanied by a decrease in cardiac index and systemic oxygen transport. Whether or not such a vasoconstriction impedes regional blood flow and thus visceral organ function, even when low AVP is used, is still a matter of debate. Krejci and...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章,评审


    authors: Bracht H,Asfar P,Radermacher P,Calzia E

    更新日期:2007-01-01 00:00:00