Abstract:
:The aim of perioperative haemodilution is to reduce loss of red blood cells during elective surgery. The oncotic and molecular characteristics of the various plasma substitutes employed determine how effectively normovolaemia is maintained, and their non-oncotic effects include alterations in microvascular perfusion. In the previous issue of Critical Care, Martini and colleagues assessed the effects of haemodilution with either polyethylene glycol (PEG)ylated albumin or a commercially available hydroxyethyl starch-based colloid in a hamster haemorrhage model. PEGylated albumin was superior to hydroxyethyl starch, as reflected by survival, haemodynamic parameters and assessment of the microcirculation using intravital microscopy.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Creagh-Brown BC,Evans TWdoi
10.1186/cc6892subject
Has Abstractpub_date
2008-01-01 00:00:00pages
147issue
3eissn
1364-8535issn
1466-609Xpii
cc6892journal_volume
12pub_type
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