Changes in central venous saturation after major surgery, and association with outcome.

abstract：INTRODUCTION:We compared the effects of mechanical ventilation with a lower tidal volume (V(T)) strategy versus those of greater V(T) in patients with or without acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) on the use of opioids and sedatives. METHODS:This is a secondary analysis of a previously ...

journal_title：Critical care (London, England)

authors： Wolthuis EK,Veelo DP,Choi G,Determann RM,Korevaar JC,Spronk PE,Kuiper MA,Schultz MJ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related to increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) is increasingly used as an indirect measure of ICP, and quantitative EEG (QEEG) can ...

journal_title：Critical care (London, England)

authors： Chen Y,Xu W,Wang L,Yin X,Cao J,Deng F,Xing Y,Feng J

更新日期：2018-02-20 00:00:00

abstract：BACKGROUND:Effective antimicrobial treatment is key to reduce mortality associated with bacterial sepsis in patients on intensive care units (ICUs). Dose adjustments are often necessary to account for pathophysiological changes or renal replacement therapy. Extracorporeal membrane oxygenation (ECMO) is increasingly bei...

journal_title：Critical care (London, England)

authors： Kühn D,Metz C,Seiler F,Wehrfritz H,Roth S,Alqudrah M,Becker A,Bracht H,Wagenpfeil S,Hoffmann M,Bals R,Hübner U,Geisel J,Lepper PM,Becker SL

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:Herpes simplex virus (HSV) is frequently detected in the respiratory tract of mechanically ventilated patients. The aim of this study was to assess current evidence to determine whether antiviral therapy is associated with better outcomes in these patients. METHODS:MEDLINE, ISI Web of Science, Cochrane Data...

journal_title：Critical care (London, England)

authors： Hagel S,Scherag A,Schuierer L,Hoffmann R,Luyt CE,Pletz MW,Kesselmeier M,Weis S

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:In patients intubated for mechanical ventilation, prolonged diaphragm inactivity could lead to weakness and poor outcome. Time to resume a minimal diaphragm activity may be related to sedation practice and patient severity. METHODS:Prospective observational study in critically ill patients. Diaphragm electr...

journal_title：Critical care (London, England)

authors： Sklar MC,Madotto F,Jonkman A,Rauseo M,Soliman I,Damiani LF,Telias I,Dubo S,Chen L,Rittayamai N,Chen GQ,Goligher EC,Dres M,Coudroy R,Pham T,Artigas RM,Friedrich JO,Sinderby C,Heunks L,Brochard L

更新日期：2021-01-11 00:00:00

abstract：INTRODUCTION:Recent evidence suggests a link between excess lipid peroxidation and specific organ failures in sepsis. No study has been performed in sepsis by multidrug-resistant (MDR) Gram-negative bacteria. METHODS:Lethal sepsis was induced in rats by the intraperitoneal injection of one MDR isolate of Pseudomonas a...

journal_title：Critical care (London, England)

authors： Toufekoula C,Papadakis V,Tsaganos T,Routsi C,Orfanos SE,Kotanidou A,Carrer DP,Raftogiannis M,Baziaka F,Giamarellos-Bourboulis EJ

更新日期：2013-01-16 00:00:00

abstract：:Acute pancreatitis is an inflammatory disease process which may present with clinical manifestations ranging from benign self-limited disease to overwhelming sepsis. The ability to predict outcome would be helpful in developing treatment plans, and possibly in stratifying patients for clinical trials. ...

journal_title：Critical care (London, England)

authors： Rotstein OD

更新日期：2014-10-20 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether the provision of corticosteroids improves time to shock reversal and outcomes in patients with post-cardiac arrest shock. METHODS:We conducted a randomized, double-blind trial of post-cardiac arrest patients in shock, defined as vasopressor support for a mi...

journal_title：Critical care (London, England)

authors： Donnino MW,Andersen LW,Berg KM,Chase M,Sherwin R,Smithline H,Carney E,Ngo L,Patel PV,Liu X,Cutlip D,Zimetbaum P,Cocchi MN,Collaborating Authors from the Beth Israel Deaconess Medical Center’s Center for Resuscitation Science Re

更新日期：2016-04-03 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is a frequent complication after cardiac surgery with cardiopulmonary bypass in infants. Renal near-infrared spectroscopy (NIRS) is used to evaluate regional oximetry in a non-invasive continuous real-time fashion, and reflects tissue perfusion. The aim of this study was to evalua...

journal_title：Critical care (London, England)

authors： Ruf B,Bonelli V,Balling G,Hörer J,Nagdyman N,Braun SL,Ewert P,Reiter K

更新日期：2015-01-29 00:00:00

abstract：INTRODUCTION AND METHODS:Dynamic fluorescence quenching is a technique that may overcome some of the limitations associated with measurement of tissue partial oxygen tension (PO2). We compared this technique with a polarographic Eppendorf needle electrode method using a saline tonometer in which the PO2 could be contro...

journal_title：Critical care (London, England)

authors： Shaw AD,Li Z,Thomas Z,Stevens CW

更新日期：2002-02-01 00:00:00

abstract：INTRODUCTION:The pathophysiology of acute kidney injury (AKI) in sepsis is ill defined. We investigated parameters associated with low glomerular filtration, and their predictive value to discriminate transient from intrinsic septic AKI. METHODS:In 107 sepsis patients, AKI was defined by the Risk, Injury, Failure, Los...

journal_title：Critical care (London, England)

authors： Vanmassenhove J,Glorieux G,Hoste E,Dhondt A,Vanholder R,Van Biesen W

更新日期：2013-10-13 00:00:00

abstract：INTRODUCTION:The aetiology of lower respiratory tract infections in young children admitted to the paediatric intensive care unit (PICU) is often difficult to establish. However, most infections are believed to be caused by respiratory viruses. A diagnostic study was performed to compare conventional viral tests with t...

journal_title：Critical care (London, England)

authors： van de Pol AC,Wolfs TF,Jansen NJ,van Loon AM,Rossen JW

更新日期：2006-01-01 00:00:00

abstract：:The epidemiology of severe acute renal failure has dramatically changed in the past decade. Its leading cause is sepsis and the syndrome develops mostly in the intensive care unit as part of multiple organ dysfunction syndrome. After the significant improvements obtained from the mid 1970s to the mid 1990s, the past d...

journal_title：Critical care (London, England)

authors： Ronco C

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Frequency-dependent acceleration of relaxation (FDAR) ensures appropriate ventricular filling at high heart rates and results from accelerated sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) activity independent of calcium removal from the cell. Because lipopolysaccharide (LPS) challenge may indu...

journal_title：Critical care (London, England)

authors： Joulin O,Marechaux S,Hassoun S,Montaigne D,Lancel S,Neviere R

更新日期：2009-01-01 00:00:00

abstract：:Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...

journal_title：Critical care (London, England)

authors： Alansari M,Alotair H,Al Aseri Z,Elhoseny MA

更新日期：2015-05-18 00:00:00

abstract：INTRODUCTION:The ventilator and the endotracheal tube impose additional workload in mechanically ventilated patients breathing spontaneously. The total work of breathing (WOB) includes elastic and resistive work. In a bench test we assessed the imposed WOB using 3100 A/3100 B SensorMedics high-frequency oscillatory ven...

journal_title：Critical care (London, England)

authors： van Heerde M,van Genderingen HR,Leenhoven T,Roubik K,Plötz FB,Markhorst DG

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:As more patients are surviving intensive care, mental health concerns in survivors have become a research priority. Among these, post-traumatic stress disorder (PTSD) can have an important impact on the quality of life of critical care survivors. However, data on its burden are conflicting. Therefore, this s...

journal_title：Critical care (London, England)

authors： Righy C,Rosa RG,da Silva RTA,Kochhann R,Migliavaca CB,Robinson CC,Teche SP,Teixeira C,Bozza FA,Falavigna M

更新日期：2019-06-11 00:00:00

abstract：INTRODUCTION:Prothrombin complex concentrates (PCC) are haemostatic blood preparations indicated for urgent anticoagulation reversal, though the optimal dose for effective reversal is still under debate. The latest generation of PCCs include four coagulation factors, the so-called 4-factor PCC. The aim of this study wa...

journal_title：Critical care (London, England)

authors： Kerebel D,Joly LM,Honnart D,Schmidt J,Galanaud D,Negrier C,Kursten F,Coriat P,Lex206 Investigator Group.

更新日期：2013-01-10 00:00:00

abstract：INTRODUCTION:Patients admitted to the intensive care unit often develop hyperglycaemia, but the underlying mechanisms have not been fully described. The incretin effect is reduced in patients with type 2 diabetes. Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resis...

journal_title：Critical care (London, England)

authors： Nielsen ST,Janum S,Krogh-Madsen R,Solomon TP,Møller K

更新日期：2015-11-16 00:00:00

abstract：INTRODUCTION:Although activation of A3 adenosine receptors attenuates reperfusion lung injury and associated apoptosis, the signaling pathway that mediates this protection remains unclear. Adenosine agonists activate mitogen-activated protein kinases, and these kinases have been implicated in ischemia/reperfusion injur...

journal_title：Critical care (London, England)

authors： Matot I,Weiniger CF,Zeira E,Galun E,Joshi BV,Jacobson KA

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:There has been dramatic improvement in survival for patients with HIV/AIDS; however, some studies on patients with HIV/AIDS and serious illness have reported continued low rates of intensive care. The purpose of this study was to examine patterns of care and outcomes for patients with severe sepsis and HIV...

journal_title：Critical care (London, England)

authors： Mrus JM,Braun L,Yi MS,Linde-Zwirble WT,Johnston JA

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:The present study examined the median survival, life expectancies, and cumulative incidence rate (CIR) of patients undergoing prolonged mechanical ventilation (PMV) stratified by different underlying diseases. METHODS:According to the National Health Insurance Research Database of Taiwan, there were 8,906...

journal_title：Critical care (London, England)

authors： Hung MC,Lu HM,Chen L,Hu FC,Chan SY,Yan YH,Fan PS,Lin MS,Chen CR,Kuo LC,Yu CJ,Wang JD

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The intestinal microbiota plays a crucial role in human health, which could affect host immunity and the susceptibility to infectious diseases. However, the role of intestinal microbiota in the immunopathology of invasive candidiasis remains unknown. METHODS:In this work, an antibiotic cocktail was used to ...

journal_title：Critical care (London, England)

authors： Li M,Li C,Wu X,Chen T,Ren L,Xu B,Cao J

更新日期：2020-05-27 00:00:00

abstract：:Many advances in medicine have been achieved through challenging established dogma with revolutionary thought and novel practices. Each and every specialty is reinvigorated by regular re-evaluation of processes and practices in the light of new evidence and fresh conceptualization. Challenge can galvanize fresh thinki...

journal_title：Critical care (London, England)

authors： Singer M,Matthay MA

更新日期：2011-07-26 00:00:00

abstract：INTRODUCTION:The frequency and clinical significance of polymicrobial aetiology in community-acquired pneumonia (CAP) patients admitted to the ICU have been poorly studied. The aim of the present study was to describe the prevalence, clinical characteristics and outcomes of severe CAP of polymicrobial aetiology in pati...

journal_title：Critical care (London, England)

authors： Cillóniz C,Ewig S,Ferrer M,Polverino E,Gabarrús A,Puig de la Bellacasa J,Mensa J,Torres A

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Appropriate care for patients with tracheostomies in hospital settings is an important issue. Each year more than 7000 patients receive tracheostomies in Australia and New Zealand alone. Many of these tracheostomy patients commence their care in the intensive care unit (ICU) and once stabilised are then tr...

journal_title：Critical care (London, England)

authors： Garrubba M,Turner T,Grieveson C

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Ventilation according to the open lung concept (OLC) consists of recruitment maneuvers, followed by low tidal volume and high positive end-expiratory pressure, aiming at minimizing atelectasis. The minimization of atelectasis reduces the right ventricular (RV) afterload, but the increased intrathoracic pre...

journal_title：Critical care (London, England)

authors： Miranda DR,Klompe L,Cademartiri F,Haitsma JJ,Palumbo A,Takkenberg JJ,Lachmann B,Bogers AJ,Gommers D

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Delirium occurs in most ventilated patients and is independently associated with more deaths, longer stay, and higher cost. Guidelines recommend monitoring of delirium in all intensive care unit (ICU) patients, though few data exist in non-ventilated patients. The study objective was to determine the relat...

journal_title：Critical care (London, England)

authors： Thomason JW,Shintani A,Peterson JF,Pun BT,Jackson JC,Ely EW

更新日期：2005-08-01 00:00:00

abstract：:Carbon dioxide is a waste product of aerobic cellular respiration in all aerobic life forms. PaCO2 represents the balance between the carbon dioxide produced and that eliminated. Hypocapnia remains a common - and generally underappreciated - component of many disease states, including early asthma, high-altitude pulmo...

journal_title：Critical care (London, England)

authors： Curley G,Laffey JG,Kavanagh BP

更新日期：2010-01-01 00:00:00

abstract：:In the previous issue of Critical Care, Ma and colleagues perform a meta-analysis of five randomized, clinical trials of endothelin antagonists in patients with aneurysmal subarachnoid hemorrhage. There are four trials using clazosentan and one trial with TAK-044. These studies show that endothelin plays an important ...

journal_title：Critical care (London, England)

authors： Macdonald RL

更新日期：2012-11-09 00:00:00