Abstract:
:During the past 50 years, caring for the critically ill has become increasingly complex and the need for an intensivist has become more evident. Management by intensivists has become a quality indicator for many ICUs. Numerous small studies have demonstrated the beneficial effect of intensivists on outcomes in the critically ill, and some clinicians have advanced the argument that a night-time intensivist is essential for the care of critically ill patients. In response, many institutions have hired full-time intensivists for both day and night coverage in the ICU. Two recent studies have been conducted that make a compelling argument for redirecting funding of night-time intensivists to areas of greater need in health care. In a retrospective analysis of a large database that involved more than 65,000 patients, no benefit of night-time intensivists could be found in ICUs where care is managed by intensivists during the day. Only in ICUs where management by intensivists is not mandated could a beneficial impact on mortality be found. The second study, a randomized controlled trial, evaluated the effect of night-time intensivists on length of stay, mortality, and other outcomes and was a negative trial. In this methodologically rigorous trial, there was no difference in outcomes between the intensivist and control group, which consisted of in-house resident coverage at night with availability by telephone of fellows and intensivists. These two robust studies clearly suggest that night-time intensivists do not improve mortality in ICUs managed by intensivists during the day. Though possibly beneficial in low-intensity environments, the widespread drive to add night-time intensivist coverage may have been premature.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Levy MMdoi
10.1186/cc13060subject
Has Abstractpub_date
2013-10-14 00:00:00pages
1008issue
5eissn
1364-8535issn
1466-609Xpii
cc13060journal_volume
17pub_type
杂志文章,评审相关文献
CRITICAL CARE文献大全abstract::In a group of postoperative patients, Taniguchi and coworkers compared the effect of a computerized system for weaning against 'manual care'. The computerized system involved automatic adjustments to the level of pressure support to achieve a target respiratory rate. Manual care involved adjustments to the level of pr...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc7746
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:The present study examined the median survival, life expectancies, and cumulative incidence rate (CIR) of patients undergoing prolonged mechanical ventilation (PMV) stratified by different underlying diseases. METHODS:According to the National Health Insurance Research Database of Taiwan, there were 8,906...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10128
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Despite recent modifications, the clinical definition of the acute respiratory distress syndrome (ARDS) remains non-specific, leading to under-diagnosis and under-treatment. This study was designed to test the hypothesis that a biomarker panel would be useful for biologic confirmation of the clinical diagn...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13080
更新日期:2013-10-24 00:00:00
abstract::The early detection and treatment of sepsis are the most important factors in improving the outcome of patients with this condition. However, many patients admitted to hospital experience a long delay in the diagnosis of sepsis. Furthermore, it is not uncommon for febrile patients to be sent home from the Emergency De...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/s13054-014-0529-6
更新日期:2014-09-27 00:00:00
abstract:INTRODUCTION:In patients with acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS), recent randomised controlled trials (RCTs) showed a consistent trend of mortality reduction with prone ventilation. We updated a meta-analysis on this topic. METHODS:RCTs that compared ventilation of adult patients...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析
doi:10.1186/cc9403
更新日期:2011-01-01 00:00:00
abstract::Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthe...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc13120
更新日期:2013-11-19 00:00:00
abstract::The attack on the World Trade Center had the potential to overwhelm New York's health services. Sadly, however, the predicted thousands of treatable patients failed to materialize. Horror and sadness has now been replaced by anger, fear, and the determination to be better prepared next time. This determination not onl...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1053
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Atherosclerotic intracranial arterial stenosis is an important cause of stroke that is increasingly being treated with percutaneous transluminal angioplasty and stenting (PTAS) to prevent recurrent stroke. However, PTAS has not been compared with medical management in a randomized trial. METHODS:Objective: ...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc11326
更新日期:2012-05-09 00:00:00
abstract:INTRODUCTION:The objective was to study the effects of a novel lung volume optimization procedure (LVOP) using high-frequency oscillatory ventilation (HFOV) upon gas exchange, the transpulmonary pressure (TPP), and hemodynamics in a porcine model of surfactant depletion. METHODS:With institutional review board approva...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5052
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Temperature management is used with increased frequency as a tool to mitigate neurological injury. Although frequently used, little is known about the optimal cooling methods for inducing and maintaining controlled normo- and hypothermia in the intensive care unit (ICU). In this study we compared the efficac...
journal_title:Critical care (London, England)
pub_type: 杂志文章,随机对照试验
doi:10.1186/cc6104
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:To provide up-to-date information on the prognostic factors associated with 28-day mortality in a cohort of septic shock patients in intensive care units (ICUs). METHODS:Prospective, multicenter, observational cohort study in ICUs from 14 French general (non-academic) and university teaching hospitals. Al...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/cc12598
更新日期:2013-04-25 00:00:00
abstract:BACKGROUND:Intensive care medicine is a relatively young discipline that has rapidly grown into a full-fledged medical subspecialty. Intensivists are responsible for managing an ever-increasing number of patients with complex, life-threatening diseases. Several factors may influence their performance, including age, tr...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-018-1956-6
更新日期:2018-02-21 00:00:00
abstract:INTRODUCTION:This systematic review looks at the use of noninvasive ventilation (NIV), inclusive of noninvasive positive pressure ventilation (NPPV) and continuous positive pressure ventilation (CPAP), in patients with chest trauma to determine its safety and clinical efficacy in patients with blunt chest trauma who ar...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc12821
更新日期:2013-07-22 00:00:00
abstract::BACKGROUND: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. RESULTS: A portable, battery-powered blood analyzer was used on patients in life threatening conditions to determine pH, pCO2, pO2, sodium, potassium and ionized c...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc108
更新日期:1997-01-01 00:00:00
abstract::The pathogenesis of septic acute kidney injury (AKI) is not well understood. In the present issue of Critical Care, the combined clinical and experimental study from Mariano's group provides new insight into the disease. The study shows that plasma from septic burn patients with acute renal failure initiated pro-apopt...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc6798
更新日期:2008-01-01 00:00:00
abstract::A relative immunosuppression is observed in patients after sepsis, trauma, burns, or any severe insults. It is currently proposed that selected patients will benefit from treatment aimed at boosting their immune systems. However, the host immune response needs to be considered in context with pathogen-type, timing,and...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc13787
更新日期:2014-03-24 00:00:00
abstract:INTRODUCTION:Protocols for the delivery of analgesia, sedation and delirium care of the critically ill, mechanically ventilated patient have been shown to improve outcomes but are not uniformly used. The extent to which elements of analgesia, sedation and delirium guidelines are incorporated into order sets at hospital...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/cc11390
更新日期:2012-06-18 00:00:00
abstract:BACKGROUND:The intestinal microbiota plays a crucial role in human health, which could affect host immunity and the susceptibility to infectious diseases. However, the role of intestinal microbiota in the immunopathology of invasive candidiasis remains unknown. METHODS:In this work, an antibiotic cocktail was used to ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-020-02977-5
更新日期:2020-05-27 00:00:00
abstract::Mechanically ventilated, intubated patients are at increased risk for tracheal colonization with bacterial pathogens that may progress to heavy bacterial colonization, ventilator-associated tracheobronchitis (VAT), and/or ventilator-associated pneumonia (VAP). Previous studies report that 10 to 30 % of patients with V...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-016-1472-5
更新日期:2016-09-29 00:00:00
abstract:BACKGROUND:Septic shock (SS) and cardiogenic shock (CS) are two types of circulatory shock with a different etiology. Several studies have described the molecular alterations in SS patients, whereas the molecular factors involved in CS have been poorly investigated. We aimed to assess in the whole blood of CS and SS pa...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/s13054-019-2670-8
更新日期:2019-12-19 00:00:00
abstract::Climate change and environmental stewardship are phrases that have been defining the past few decades and promoting change in our societies. The sensitivities of intensive care as a specialty make the process of greening an intensive care unit a challenge, but not one that is insurmountable. This paper discusses oppor...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc9409
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Patients with COVID-19 (COVID) may develop acute respiratory distress syndrome with or without sepsis, coagulopathy and visceral damage. While chest CT scans are routinely performed in the initial assessment of patients with severe pulmonary forms, thymus involvement and reactivation have not been investigat...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-020-03440-1
更新日期:2021-01-04 00:00:00
abstract::The majority of intensive care practitioners, until comparatively recently, was content to discharge surviving patients to the care of referring primary specialty colleagues who would undertake subsequent inpatient and outpatient care. With the exception of mortality statistics from clinical studies, the practitioners...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1532
更新日期:2002-10-01 00:00:00
abstract:INTRODUCTION:Multiple organ dysfunction syndrome (MODS) is a common complication of sepsis in mechanically ventilated patients with acute respiratory distress syndrome, but the links between mechanical ventilation and MODS are unclear. Our goal was to determine whether a minimally injurious mechanical ventilation strat...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5050
更新日期:2006-01-01 00:00:00
abstract::Until relatively recently, critical illness was considered as a separate entity and the intensive care unit (ICU), often a little cut-off from other areas of the hospital, was in many cases used as a last resort for patients so severely ill that it was no longer possible to care for them on the general ward. However, ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-019-2393-x
更新日期:2019-06-14 00:00:00
abstract:INTRODUCTION:Deregulated apoptosis and overshooting neutrophil functions contribute to immune and organ dysfunction in sepsis and multiple organ failure (MOF). In the present study, we determined the role of soluble Fas (sFas) in the regulation of posttraumatic neutrophil extrinsic apoptosis and the development of seps...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc9965
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Mechanical ventilation with even moderate-sized tidal volumes synergistically increases lung injury in sepsis and has been associated with proinflammatory low-molecular-weight hyaluronan production. High-molecular-weight hyaluronan (HMW HA), in contrast, has been found to be anti-inflammatory. We hypothesi...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc6982
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Severe acute pancreatitis (SAP) requiring admission to a critical care unit is associated with high mortality and long lengths of stay. We describe the case mix, outcome, and activity of admissions with SAP who were identified from a high-quality clinical database. METHODS:We conducted a secondary analysi...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5682
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:We conducted an ultrasound study to investigate echocardiographic artifacts in mechanically ventilated patients with lung pathology. METHODS:A total of 205 mechanically ventilated patients who exhibited lung atelectasis and/or pleural effusion were included in this 36-month study. The patients underwent l...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc7021
更新日期:2008-01-01 00:00:00
abstract::Respiratory tract obstruction due to a blood clot may result in life threatening ventilatory impairment. Ball valve blood clot obstructions of the airways are rare. A ball valve blood clot acts as a one-way valve, allowing (near) normal air entry into the airways, but (completely) blocking expiration. In a near fatal ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc2903
更新日期:2004-10-01 00:00:00