Increased serum soluble Fas after major trauma is associated with delayed neutrophil apoptosis and development of sepsis.

abstract：:The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basic scientists and clinicians to share recent findings. Apart from the large number of free communications, several sessions of the congress were dedicated to state-of-the-art tutorials given by established speakers. The areas...

journal_title：Critical care (London, England)

authors： Preiser JC

更新日期：2001-12-01 00:00:00

abstract：:Fluid resuscitation is a cornerstone of intensive care unit patient care, but prediction of the cardiovascular response remains difficult, despite many efforts in clinical research. The concept of responders and nonresponders illustrates such a difficulty. Many techniques have been tested, from strictly non-invasive t...

journal_title：Critical care (London, England)

authors： Payen D

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Prompt diagnosis of candidaemia and invasive candidosis is crucial to the early initiation of antifungal therapy. The poor sensitivity of blood cultures (BCs) has led to the development of fungal glycan tests as a diagnostic adjunct. We analysed the performance of tests for the detection of circulating β-D...

journal_title：Critical care (London, England)

authors： Poissy J,Sendid B,Damiens S,Ichi Ishibashi K,François N,Kauv M,Favory R,Mathieu D,Poulain D

更新日期：2014-06-29 00:00:00

abstract：:High mobility group box protein 1 (HMGB1) has been shown to participate in acute inflammatory reactions, including acute lung injury and sepsis. There is also evidence that circulating levels of HMGB1 are increased after severe trauma and are associated with clinically important outcome parameters, including mortality...

journal_title：Critical care (London, England)

authors： Abraham E

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Refractory status epilepticus (RSE) secondary to traumatic brain injury (TBI) may be under-recognized and is associated with significant morbidity and mortality. METHODS:This case report describes a 20 year old previously healthy woman who suffered a severe TBI as a result of a motor vehicle collision and...

journal_title：Critical care (London, England)

authors： Peets AD,Berthiaume LR,Bagshaw SM,Federico P,Doig CJ,Zygun DA

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is common among intensive care unit (ICU) patients. AKI is highly heterogeneous, with variable links to poor outcomes. Current approaches to classify AKI severity and identify patients at highest risk for poor outcomes focus on the maximum change in serum creatinine (SCr) values. Ho...

journal_title：Critical care (London, England)

authors： Bhatraju PK,Mukherjee P,Robinson-Cohen C,O'Keefe GE,Frank AJ,Christie JD,Meyer NJ,Liu KD,Matthay MA,Calfee CS,Christiani DC,Himmelfarb J,Wurfel MM

更新日期：2016-11-17 00:00:00

abstract：BACKGROUND:Post-resuscitation hemodynamic instability following out-of-hospital cardiac arrest (OHCA) may occur from myocardial dysfunction underlying cardiogenic shock and/or inflammation-mediated distributive shock. Distinguishing the predominant shock subtype with widely available clinical metrics may have prognosti...

journal_title：Critical care (London, England)

authors： Anderson RJ,Jinadasa SP,Hsu L,Ghafouri TB,Tyagi S,Joshua J,Mueller A,Talmor D,Sell RE,Beitler JR

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:Passive leg raising (PLR) is a simple reversible maneuver that mimics rapid fluid loading and increases cardiac preload. The effects of this endogenous volume expansion on stroke volume enable the testing of fluid responsiveness with accuracy in spontaneously breathing patients. However, this maneuver requ...

journal_title：Critical care (London, England)

authors： Biais M,Vidil L,Sarrabay P,Cottenceau V,Revel P,Sztark F

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Prognosis in patients suffering out-of-hospital cardiac arrest is poor. Higher survival rates have been observed only in patients with ventricular fibrillation who were fortunate enough to have basic and advanced life support initiated soon after cardiac arrest. An ability to predict cardiac arrest outcome...

journal_title：Critical care (London, England)

authors： Kolar M,Krizmaric M,Klemen P,Grmec S

更新日期：2008-01-01 00:00:00

abstract：:Body cell mass (BCM) is the metabolically active cell mass involved in O₂ consumption, CO₂ production and energy expenditure. BCM measurement has been suggested as a tool for the evaluation of nutritional status. Since BCM is closely related to energy expenditure, it could also represent a good reference value for the...

journal_title：Critical care (London, England)

authors： Fiaccadori E,Morabito S,Cabassi A,Regolisti G

更新日期：2014-05-01 00:00:00

abstract：INTRODUCTION:ICU-acquired weakness (ICUAW) complicates the disease course of critically ill patients. Inflammation and acute-phase response occur directly within myocytes and contribute to ICUAW. We observed that tripartite motif-containing 62 (TRIM62), an E3 ubiquitin ligase and modifier of inflammation, is increased ...

journal_title：Critical care (London, England)

authors： Schmidt F,Kny M,Zhu X,Wollersheim T,Persicke K,Langhans C,Lodka D,Kleber C,Weber-Carstens S,Fielitz J

更新日期：2014-09-29 00:00:00

abstract：:There are many controversial issues surrounding ethics in study design and conduct of human subjects research. In this review we briefly touch on the origin of ethics in clinical research and how the current regulations and standards came into practice. We then discuss current controversies regarding informed consent,...

journal_title：Critical care (London, England)

authors： Huang DT,Hadian M

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Delayed patient admission to the intensive care unit (ICU) due to lack of bed availability is a common problem, but the effect on patient outcome is not fully known. METHODS:A retrospective study was performed using departmental computerised records to determine the effect of delayed ICU admission and tem...

journal_title：Critical care (London, England)

authors： O'Callaghan DJ,Jayia P,Vaughan-Huxley E,Gribbon M,Templeton M,Skipworth JR,Gordon AC

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:A paucity of literature exists regarding delays in transfer out of the intensive care unit. We sought to analyze the incidence, causes, and costs of delayed transfer from a surgical intensive care unit (SICU). METHODS:An IRB-approved prospective observational study was conducted from January 24, 2010, to ...

journal_title：Critical care (London, England)

authors： Johnson DW,Schmidt UH,Bittner EA,Christensen B,Levi R,Pino RM

更新日期：2013-07-04 00:00:00

abstract：:There has been a lot of debate about the concept of relative adrenocortical insufficiency (often defined as a reduced response to corticotropin) as a pathophysiological explanation of steroid effects in septic shock. Less is known about the prevalence of absolute adrenocortical insufficiency based on more usual defini...

journal_title：Critical care (London, England)

authors： Bollaert PE

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The short-term and long-term consequences of the most frequent painful procedures performed in the ICU are unclear. This study aimed to identify the risk factors associated with pain-related discomfort perceived by critically ill patients during the whole ICU stay as self-reported by patients at the end of t...

journal_title：Critical care (London, England)

authors： Kalfon P,Boucekine M,Estagnasie P,Geantot MA,Berric A,Simon G,Floccard B,Signouret T,Fromentin M,Nyunga M,Audibert J,Ben Salah A,Mauchien B,Sossou A,Venot M,Robert R,Follin A,Renault A,Garrouste-Orgeas M,Collange O

更新日期：2020-12-07 00:00:00

abstract：INTRODUCTION:A lack of data exists in the literature evaluating acidemia on admission as a favorable or negative prognostic factor in patients with acute cardiogenic pulmonary edema (ACPE) treated with non-invasive continuous positive airway pressure (CPAP). The objective of the present study was to investigate the imp...

journal_title：Critical care (London, England)

authors： Aliberti S,Piffer F,Brambilla AM,Bignamini AA,Rosti VD,Maraffi T,Monzani V,Cosentini R

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:In ARDS patients, changes in respiratory mechanical properties and ventilatory settings can cause incomplete lung deflation at end-expiration. Both can promote dynamic hyperinflation and intrinsic positive end-expiratory pressure (PEEP). The aim of this study was to investigate, in a large population of ARDS...

journal_title：Critical care (London, England)

authors： Coppola S,Caccioppola A,Froio S,Ferrari E,Gotti M,Formenti P,Chiumello D

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Electrical impedance tomography (EIT) is a non-invasive bedside tool which allows an individualized ventilator strategy by monitoring tidal ventilation and lung aeration. EIT can be performed at different cranio-caudal thoracic levels, but data are missing about the optimal belt position. The main goal of th...

journal_title：Critical care (London, England)

authors： Karsten J,Stueber T,Voigt N,Teschner E,Heinze H

更新日期：2016-01-08 00:00:00

abstract：INTRODUCTION:Angiopoietin-2 (ang-2), an angiogenic peptide released by endothelial cell Weibel-Palade bodies (WPBs), increases endothelial activation and vascular permeability. Ang-2 is raised in severe sepsis but the mechanisms underlying this are not known. Nitric oxide (NO) inhibits WPB exocytosis, and bioavailabili...

journal_title：Critical care (London, England)

authors： Davis JS,Yeo TW,Piera KA,Woodberry T,Celermajer DS,Stephens DP,Anstey NM

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The main objective was to determine risk factors for presence of multidrug resistant bacteria (MDR) in postoperative peritonitis (PP) and optimal empirical antibiotic therapy (EA) among options proposed by Infectious Disease Society of America and the Surgical Infection Society guidelines. METHODS:One hun...

journal_title：Critical care (London, England)

authors： Augustin P,Kermarrec N,Muller-Serieys C,Lasocki S,Chosidow D,Marmuse JP,Valin N,Desmonts JM,Montravers P

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The pathophysiology of postoperative delirium remains poorly understood. The purpose of this study was to examine the relationship between serum cortisol level and occurrence of early postoperative delirium in patients undergoing coronary artery bypass graft (CABG) surgery. METHODS:A total of 243 patients...

journal_title：Critical care (London, England)

authors： Mu DL,Wang DX,Li LH,Shan GJ,Li J,Yu QJ,Shi CX

更新日期：2010-01-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available f...

journal_title：Critical care (London, England)

authors： Al-Dorzi HM,Alsolamy S,Arabi YM

更新日期：2016-03-16 00:00:00

abstract：:Certain noble gases, though inert, exhibit remarkable biological properties. Notably, xenon and argon provide neuroprotection in animal models of central nervous system injury. In the previous issue of Critical Care, Loetscher and colleagues provided further evidence that argon may have therapeutic properties for neur...

journal_title：Critical care (London, England)

authors： Sanders RD,Ma D,Maze M

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Functional assessment of arterial load by dynamic arterial elastance (Eadyn), defined as the ratio between pulse pressure variation (PPV) and stroke volume variation (SVV), has recently been shown to predict the arterial pressure response to volume expansion (VE) in hypotensive, preload-dependent patients....

journal_title：Critical care (London, England)

authors： García MI,Romero MG,Cano AG,Aya HD,Rhodes A,Grounds RM,Cecconi M

更新日期：2014-11-19 00:00:00

abstract：INTRODUCTION:New technology using partial carbon dioxide rebreathing has been developed to measure cardiac output. Because rebreathing increases respiratory effort, we investigated whether a newly developed system with 35 s rebreathing causes a lesser increase in respiratory effort under partial ventilatory support tha...

journal_title：Critical care (London, England)

authors： Tachibana K,Imanaka H,Takeuchi M,Nishida T,Takauchi Y,Nishimura M

更新日期：2005-10-05 00:00:00

abstract：INTRODUCTION:To systematically review studies evaluating the performance of Sequential Organ Failure Assessment (SOFA)-based models for predicting mortality in patients in the intensive care unit (ICU). METHODS:Medline, EMBASE and other databases were searched for English-language articles with the major objective of ...

journal_title：Critical care (London, England)

authors： Minne L,Abu-Hanna A,de Jonge E

更新日期：2008-01-01 00:00:00

abstract：:Percutaneous dilatation tracheostomy in the intensive care setting presents an increasingly important concept for establishing a large-bore tracheal airway with minimal surgical intervention. Over the last years, different technical solutions have been studied to assess their respective risks and benefits to determine...

journal_title：Critical care (London, England)

authors： Brambrink A

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen concentrate, which may have advantages of more rapid administrati...

journal_title：Critical care (London, England)

authors： Curry N,Foley C,Wong H,Mora A,Curnow E,Zarankaite A,Hodge R,Hopkins V,Deary A,Ray J,Moss P,Reed MJ,Kellett S,Davenport R,Stanworth S

更新日期：2018-06-18 00:00:00

abstract：:Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...

journal_title：Critical care (London, England)

authors： Schneider AG,Journois D,Rimmelé T

更新日期：2017-11-19 00:00:00