Abstract:
:A relative immunosuppression is observed in patients after sepsis, trauma, burns, or any severe insults. It is currently proposed that selected patients will benefit from treatment aimed at boosting their immune systems. However, the host immune response needs to be considered in context with pathogen-type, timing,and mainly tissue specificity. Indeed, the immune status of leukocytes is not universally decreased and their activated status in tissues contributes to organ failure. Accordingly, any new immune-stimulatory therapeutic intervention should take into consideration potentially deleterious effects in some situations.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Cavaillon JM,Eisen D,Annane Ddoi
10.1186/cc13787subject
Has Abstractpub_date
2014-03-24 00:00:00pages
216issue
2eissn
1364-8535issn
1466-609Xpii
cc13787journal_volume
18pub_type
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