European Society of Intensive Care Medicine 14th annual congress, 30 September-3 October 2001, Geneva, Switzerland.


:The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basic scientists and clinicians to share recent findings. Apart from the large number of free communications, several sessions of the congress were dedicated to state-of-the-art tutorials given by established speakers. The areas of interest of the attendees were widely distributed as usual, a reflection of the large array of so-called 'critical illnesses'. The results of clinical trials and experimental findings using recently developed drugs were presented, essentially in the fields of inflammation, sepsis, and acute lung injury. The benefits of several new compounds observed experimentally need to be confirmed clinically. The European Society of Intensive Care Medicine Congress is well established as a unique opportunity to implement and to promote a collaboration between European basic scientists and clinicians.


Crit Care


Preiser JC





Has Abstract


2001-12-01 00:00:00












  • Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses.

    abstract:BACKGROUND:Crystalloids and different component colloids, used for volume resuscitation, are sometimes associated with various adverse effects. Clinical trial findings for such fluid types in different patients' conditions are conflicting. Whether the mortality benefit of balanced crystalloid than saline can be inferre...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Tseng CH,Chen TT,Wu MY,Chan MC,Shih MC,Tu YK

    更新日期:2020-12-14 00:00:00

  • Acute management and outcome of multiple trauma patients with pelvic disruptions.

    abstract:INTRODUCTION:Data on prehospital and trauma-room fluid management of multiple trauma patients with pelvic disruptions are rarely reported. Present trauma algorithms recommend early hemorrhage control and massive fluid resuscitation. By matching the German Pelvic Injury Register (PIR) with the TraumaRegister DGU (TR) fo...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Burkhardt M,Nienaber U,Pizanis A,Maegele M,Culemann U,Bouillon B,Flohé S,Pohlemann T,Paffrath T,TraumaRegister DGU.,German Pelvic Injury Register of the Deutsche Gesellschaft für Unfallchirurgie.

    更新日期:2012-08-22 00:00:00

  • Long-term survival after intensive care unit discharge in Thailand: a retrospective study.

    abstract:INTRODUCTION:Economic evaluations of interventions in the hospital setting often rely on the estimated long-term impact on patient survival. Estimates of mortality rates and long-term outcomes among patients discharged alive from the intensive care unit (ICU) are lacking from lower- and middle-income countries. This st...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Luangasanatip N,Hongsuwan M,Lubell Y,Limmathurotsakul D,Teparrukkul P,Chaowarat S,Day NP,Graves N,Cooper BS

    更新日期:2013-10-03 00:00:00

  • Bench-to-bedside review: circulating microparticles--a new player in sepsis?

    abstract::In sepsis, inflammation and thrombosis are both the cause and the result of interactions between circulating (for example, leukocytes and platelets), endothelial and smooth muscle cells. Microparticles are proinflammatory and procoagulant fragments originating from plasma membrane generated after cellular activation a...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Meziani F,Delabranche X,Asfar P,Toti F

    更新日期:2010-01-01 00:00:00

  • The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients.

    abstract:INTRODUCTION:This study hypothesised that a reduction of sound during the night using earplugs could be beneficial in the prevention of intensive care delirium. Two research questions were formulated. First, does the use of earplugs during the night reduce the onset of delirium or confusion in the ICU? Second, does the...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Van Rompaey B,Elseviers MM,Van Drom W,Fromont V,Jorens PG

    更新日期:2012-05-04 00:00:00

  • Auxora versus standard of care for the treatment of severe or critical COVID-19 pneumonia: results from a randomized controlled trial.

    abstract:BACKGROUND:Calcium release-activated calcium (CRAC) channel inhibitors stabilize the pulmonary endothelium and block proinflammatory cytokine release, potentially mitigating respiratory complications observed in patients with COVID-19. This study aimed to investigate the safety and efficacy of Auxora, a novel, intraven...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Miller J,Bruen C,Schnaus M,Zhang J,Ali S,Lind A,Stoecker Z,Stauderman K,Hebbar S

    更新日期:2020-08-14 00:00:00

  • Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis.

    abstract:INTRODUCTION:The frequency and clinical significance of polymicrobial aetiology in community-acquired pneumonia (CAP) patients admitted to the ICU have been poorly studied. The aim of the present study was to describe the prevalence, clinical characteristics and outcomes of severe CAP of polymicrobial aetiology in pati...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Cillóniz C,Ewig S,Ferrer M,Polverino E,Gabarrús A,Puig de la Bellacasa J,Mensa J,Torres A

    更新日期:2011-01-01 00:00:00

  • Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives.

    abstract:INTRODUCTION:We compared the effects of mechanical ventilation with a lower tidal volume (V(T)) strategy versus those of greater V(T) in patients with or without acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) on the use of opioids and sedatives. METHODS:This is a secondary analysis of a previously ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Wolthuis EK,Veelo DP,Choi G,Determann RM,Korevaar JC,Spronk PE,Kuiper MA,Schultz MJ

    更新日期:2007-01-01 00:00:00

  • Feasibility and reliability of an automated controller of inspired oxygen concentration during mechanical ventilation.

    abstract:INTRODUCTION:Hypoxemia and high fractions of inspired oxygen (FiO2) are concerns in critically ill patients. An automated FiO2 controller based on continuous oxygen saturation (SpO2) measurement was tested. Two different SpO2-FiO2 feedback open loops, designed to react differently based on the level of hypoxemia, were ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Saihi K,Richard JC,Gonin X,Krüger T,Dojat M,Brochard L

    更新日期:2014-02-19 00:00:00

  • Risk management in patients with severe acute pancreatitis.

    abstract::Primary or secondary infection of necrotized areas by enteral bacteria is considered a primary cause of mortality in patients with severe acute pancreatitis (SAP). Indeed, 20-30% of patients die during the course of the disease from multiple organ dysfunction after infection. This is why strategies such as antibiotic ...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Gerlach H

    更新日期:2004-12-01 00:00:00

  • Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective.

    abstract::Sepsis represents a dysregulated host response to infection, the extent of which determines the severity of organ dysfunction and subsequent outcome. All trialled immunomodulatory strategies to date have resulted in either outright failure or inconsistent degrees of success. Intravenous immunoglobulin (IVIg) therapy f...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Shankar-Hari M,Spencer J,Sewell WA,Rowan KM,Singer M

    更新日期:2012-12-12 00:00:00

  • Value of arterial blood gas analysis in patients with acute dyspnea: an observational study.

    abstract:INTRODUCTION:The diagnostic and prognostic value of arterial blood gas analysis (ABGA) parameters in unselected patients presenting with acute dyspnea to the Emergency Department (ED) is largely unknown. METHODS:We performed a post-hoc analysis of two different prospective studies to investigate the diagnostic and pro...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Burri E,Potocki M,Drexler B,Schuetz P,Mebazaa A,Ahlfeld U,Balmelli C,Heinisch C,Noveanu M,Breidthardt T,Schaub N,Reichlin T,Mueller C

    更新日期:2011-01-01 00:00:00

  • Treatment of central line-associated bloodstream infections.

    abstract:: ...

    journal_title:Critical care (London, England)

    pub_type: 社论


    authors: Guenezan J,Drugeon B,Marjanovic N,Mimoz O

    更新日期:2018-11-16 00:00:00

  • Recently published papers: from superbugs to superbowl.

    abstract::Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular re...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Tomlinson LA,Forni LG

    更新日期:2005-04-01 00:00:00

  • Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients.

    abstract:INTRODUCTION:Improved methods to optimize drug dosing in the critically ill are urgently needed. Traditional prescribing culture involves recognition of factors that mandate dose reduction (such as renal impairment), although optimizing drug exposure, through more frequent or augmented dosing, represents an evolving st...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Udy AA,Roberts JA,Shorr AF,Boots RJ,Lipman J

    更新日期:2013-02-28 00:00:00

  • Simplified lung ultrasound protocol shows excellent prediction of extravascular lung water in ventilated intensive care patients.

    abstract:INTRODUCTION:Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to evaluate a four-region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care unit. METHODS:Fift...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Enghard P,Rademacher S,Nee J,Hasper D,Engert U,Jörres A,Kruse JM

    更新日期:2015-02-06 00:00:00

  • Diagnosis and management of inhalation injury: an updated review.

    abstract::In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Walker PF,Buehner MF,Wood LA,Boyer NL,Driscoll IR,Lundy JB,Cancio LC,Chung KK

    更新日期:2015-10-28 00:00:00

  • Intensive care unit acquired muscle weakness: when should we consider rehabilitation?

    abstract::Muscle weakness is highly prevalent during acute critical illness, with the poor exercise performance that occurs after critical illness being recognized as a consequence of skeletal muscles weakness. Advanced techniques to measure peripheral muscle strength are available, but they have limited use in the clinical set...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Puthucheary Z,Hart N

    更新日期:2009-01-01 00:00:00

  • Early vs late start of dialysis: it's all about timing.

    abstract::Acute kidney injury (AKI) is now well recognized as an independent risk factor for increased morbidity and mortality, particularly when dialysis is needed. The wide variation in dialysis utilization contributes to a lack of consensus on what parameters should guide the decision to start dialysis. While the association...

    journal_title:Critical care (London, England)

    pub_type: 评论,信件


    authors: Macedo E,Mehta RL

    更新日期:2010-01-01 00:00:00

  • Clinical manifestations of disordered microcirculatory perfusion in severe sepsis.

    abstract::Microcirculatory dysfunction plays a pivotal role in the development of the clinical manifestations of severe sepsis. Prior to the advent of new imaging technologies, clinicians had been limited in their ability to assess the microcirculation at the bedside. Clinical evidence of microcirculatory perfusion has historic...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Trzeciak S,Rivers EP

    更新日期:2005-01-01 00:00:00

  • Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study.

    abstract:INTRODUCTION:Expanding the criteria for deceased organ donors increases the risk of delayed graft function (DGF) and complicates kidney transplant outcome. We studied whether donor neutrophil gelatinase-associated lipocalin (NGAL), a novel biomarker for acute kidney injury, could predict DGF after transplantation. MET...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Hollmen ME,Kyllönen LE,Inkinen KA,Lalla ML,Merenmies J,Salmela KT

    更新日期:2011-01-01 00:00:00

  • Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury.

    abstract:BACKGROUND:Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI). However, evidence regarding the prognostic effect of the platelet-to-lymphocyte ratio (PLR), a novel systemic inflammation marker, among patients with AKI is scarce. In this study, we investigated the value o...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Zheng CF,Liu WY,Zeng FF,Zheng MH,Shi HY,Zhou Y,Pan JY

    更新日期:2017-09-08 00:00:00

  • Bench-to-bedside review: weaning failure--should we rest the respiratory muscles with controlled mechanical ventilation?

    abstract::The use of controlled mechanical ventilation (CMV) in patients who experience weaning failure after a spontaneous breathing trial or after extubation is a strategy based on the premise that respiratory muscle fatigue (requiring rest to recover) is the cause of weaning failure. Recent evidence, however, does not suppor...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Vassilakopoulos T,Zakynthinos S,Roussos C

    更新日期:2006-02-01 00:00:00

  • Beyond volutrauma in ARDS: the critical role of lung tissue deformation.

    abstract::Ventilator-induced lung injury (VILI) consists of tissue damage and a biological response resulting from the application of inappropriate mechanical forces to the lung parenchyma. The current paradigm attributes VILI to overstretching due to very high-volume ventilation (volutrauma) and cyclic changes in aeration due ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Albaiceta GM,Blanch L

    更新日期:2011-04-07 00:00:00

  • Risk factors and events in the adult intensive care unit associated with pain as self-reported at the end of the intensive care unit stay.

    abstract:BACKGROUND:The short-term and long-term consequences of the most frequent painful procedures performed in the ICU are unclear. This study aimed to identify the risk factors associated with pain-related discomfort perceived by critically ill patients during the whole ICU stay as self-reported by patients at the end of t...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Kalfon P,Boucekine M,Estagnasie P,Geantot MA,Berric A,Simon G,Floccard B,Signouret T,Fromentin M,Nyunga M,Audibert J,Ben Salah A,Mauchien B,Sossou A,Venot M,Robert R,Follin A,Renault A,Garrouste-Orgeas M,Collange O

    更新日期:2020-12-07 00:00:00

  • Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture.

    abstract:INTRODUCTION:The goal of the current study was to investigate the effect of aging on the development of endothelial dysfunction in a murine model of sepsis, and to compare it with the effect of genetic deficiency of the endothelial isoform of nitric oxide synthase (eNOS). METHODS:Cecal ligation and puncture (CLP) was ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Coletta C,Módis K,Oláh G,Brunyánszki A,Herzig DS,Sherwood ER,Ungvári Z,Szabo C

    更新日期:2014-09-16 00:00:00

  • Increased β-Lactams dosing regimens improve clinical outcome in critically ill patients with augmented renal clearance treated for a first episode of hospital or ventilator-acquired pneumonia: a before and after study.

    abstract:BACKGROUND:Augmented renal clearance (ARC) is recognized as a leading cause of β-lactam subexposure when conventional dosing regimens are used. The main objective was to compare the clinical outcome of ARC patients treated by conventional or increased β-lactam dosing regimens for a first episode of hospital or ventilat...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Carrié C,Chadefaux G,Sauvage N,de Courson H,Petit L,Nouette-Gaulain K,Pereira B,Biais M

    更新日期:2019-11-27 00:00:00

  • Is acute respiratory distress syndrome an iatrogenic disease?

    abstract::In this month's issue of Critical Care, Determann and colleagues report the results of a randomized controlled trial comparing the effects of mechanical ventilation (MV) with two tidal volumes (6 versus 10 ml/kg predicted body weight) on cytokine levels in lung lavage fluid and plasma as a surrogate for early identifi...

    journal_title:Critical care (London, England)

    pub_type: 社论


    authors: Villar J,Slutsky AS

    更新日期:2010-01-01 00:00:00

  • New versus old blood - the debate continues.

    abstract::Since the inception of blood banking, refinements in laboratory processes have allowed for progressively longer storage times of red blood cells. Whilst advantageous for the logistics of stock management, the clinical impact of the duration of red blood cell storage prior to transfusion remains uncertain, and a topic ...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Laurie J,Wyncoll D,Harrison C

    更新日期:2010-01-01 00:00:00

  • Is there more to glycaemic control than meets the eye?

    abstract::Tight glycaemic control has emerged as a major focus in critical care. However, the struggle to repeat, improve and standardize the results of the initial landmark studies is ongoing. The prospective computerized glycaemic control study by Shulman et al. highlights two emerging and often overlooked aspects of intensiv...

    journal_title:Critical care (London, England)

    pub_type: 评论,社论


    authors: Chase JG,Shaw GM

    更新日期:2007-01-01 00:00:00