Abstract:
:The impressive benefits related to the use of tight glucose control by intensive insulin therapy have not been reproduced until now in multicenter large-scale prospective randomized trials. Although the reasons for these failures are not entirely clear, we suggest the use of a stepwise approach - Safe, Effective Glucose Control - that will essentially target an intermediate blood glucose level. As compared with genuine tight glucose control, Safe, Effective Glucose Control - already used in many intensive care units worldwide - is intended to decrease the rate of hypoglycemia and the workload, while reducing the adverse effects of severe hyperglycemia.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Krinsley JS,Preiser JCdoi
10.1186/cc6889subject
Has Abstractpub_date
2008-01-01 00:00:00pages
149issue
3eissn
1364-8535issn
1466-609Xpii
cc6889journal_volume
12pub_type
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