ICU admission and severity assessment in community-acquired pneumonia.

abstract：:Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...

journal_title：Critical care (London, England)

authors： Schneider AG,Journois D,Rimmelé T

更新日期：2017-11-19 00:00:00

abstract：:The rationale for the provision of nitrogen from proteins given via the enteral route or from intravenous amino acids is to boost the synthesis of muscle proteins, and thereby to limit the severity of intensive care unit-acquired weakness by the prevention of muscle loss. However, the optimal timing for supplemental n...

journal_title：Critical care (London, England)

authors： Preiser JC

更新日期：2018-10-25 00:00:00

abstract：BACKGROUND:Neurocritical illness is a growing healthcare problem with profound socioeconomic effects. We assessed differences in healthcare costs and long-term outcome for different forms of neurocritical illnesses treated in the intensive care unit (ICU). METHODS:We used the prospective Finnish Intensive Care Consort...

journal_title：Critical care (London, England)

authors： Raj R,Bendel S,Reinikainen M,Hoppu S,Laitio R,Ala-Kokko T,Curtze S,Skrifvars MB

更新日期：2018-09-20 00:00:00

abstract：:Carbon dioxide has been monitored in the body using a variety of technologies with a multitude of applications. The monitoring of this common physiologic variable in medicine is an illustrative example of the different levels of evidence that are required before any new health technology should establish itself in cli...

journal_title：Critical care (London, England)

authors： Gattas D,Ayer R,Suntharalingam G,Chapman M

更新日期：2004-08-01 00:00:00

abstract：:Activation of nuclear factor kappa-B (NF-κB) results in its translocation from the cytoplasm to the nucleus and binding to the promoters of a large number of genes, including those encoding proinflammatory cytokines and other mediators that can contribute to organ system dysfunction in severe infection. While inhibiti...

journal_title：Critical care (London, England)

authors： Abraham E

更新日期：2013-06-11 00:00:00

abstract：BACKGROUND:The safety of perioperative hyperoxia is currently unclear. Previous studies in patients undergoing coronary artery bypass surgery suggest reduced myocardial damage when avoiding extreme perioperative hyperoxia (>400 mmHg). In this study we investigated whether an oxygenation strategy from moderate hyperoxia...

journal_title：Critical care (London, England)

authors： Smit B,Smulders YM,de Waard MC,Boer C,Vonk AB,Veerhoek D,Kamminga S,de Grooth HJ,García-Vallejo JJ,Musters RJ,Girbes AR,Oudemans-van Straaten HM,Spoelstra-de Man AM

更新日期：2016-03-10 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www...

journal_title：Critical care (London, England)

authors： Tagami T,Yasunaga H,Yokota H

更新日期：2017-03-21 00:00:00

abstract：:Vasopressin (antidiuretic hormone) is emerging as a potentially major advance in the treatment of septic shock. Terlipressin (tricyl-lysine-vasopressin) is the synthetic, long-acting analogue of vasopressin, and has comparable pharmacodynamic but different pharmacokinetic properties. Vasopressin mediates vasoconstrict...

journal_title：Critical care (London, England)

authors： Delmas A,Leone M,Rousseau S,Albanèse J,Martin C

更新日期：2005-04-01 00:00:00

abstract：:There is persuasive evidence, including the present report by Dubin and colleagues, of a dissociation between increases in arterial pressure produced by vasopressor agents and improvement in microvascular perfusion and delivery of vital substrates. Especially in settings of septic shock, the current routine administra...

journal_title：Critical care (London, England)

authors： Weil MH,Tang W

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Although less invasive than pulmonary artery catheters (PACs), arterial pulse pressure analysis techniques for estimating cardiac output (CO) have not been simultaneously compared to PAC bolus thermodilution CO (COtd) or continuous CO (CCO) devices. METHODS:We compared the accuracy, bias and trending abil...

journal_title：Critical care (London, England)

authors： Hadian M,Kim HK,Severyn DA,Pinsky MR

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Deregulated apoptosis and overshooting neutrophil functions contribute to immune and organ dysfunction in sepsis and multiple organ failure (MOF). In the present study, we determined the role of soluble Fas (sFas) in the regulation of posttraumatic neutrophil extrinsic apoptosis and the development of seps...

journal_title：Critical care (London, England)

authors： Paunel-Görgülü A,Flohé S,Scholz M,Windolf J,Lögters T

更新日期：2011-01-01 00:00:00

abstract：:The diagnosis of patients presenting to the emergency department with acute heart failure (AHF) is challenging due to the similarity of AHF symptoms to other conditions such as chronic obstructive pulmonary disease and pneumonia. Additionally, because AHF is most common in an older population, the presentation of coex...

journal_title：Critical care (London, England)

authors： Peacock WF,Cannon CM,Singer AJ,Hiestand BC

更新日期：2015-11-10 00:00:00

abstract：INTRODUCTION:Sepsis is the leading cause of acute kidney injury (AKI) in critical patients. The optimal timing of initiating renal replacement therapy (RRT) in septic AKI patients remains controversial. The objective of this study is to determine the impact of early or late initiation of RRT, as defined using the simpl...

journal_title：Critical care (London, England)

authors： Chou YH,Huang TM,Wu VC,Wang CY,Shiao CC,Lai CF,Tsai HB,Chao CT,Young GH,Wang WJ,Kao TW,Lin SL,Han YY,Chou A,Lin TH,Yang YW,Chen YM,Tsai PR,Lin YF,Huang JW,Chiang WC,Chou NK,Ko WJ,Wu KD,Tsai TJ,NSARF Stud

更新日期：2011-01-01 00:00:00

abstract：:Microcirculatory dysfunction plays a pivotal role in the development of the clinical manifestations of severe sepsis. Prior to the advent of new imaging technologies, clinicians had been limited in their ability to assess the microcirculation at the bedside. Clinical evidence of microcirculatory perfusion has historic...

journal_title：Critical care (London, England)

authors： Trzeciak S,Rivers EP

更新日期：2005-01-01 00:00:00

abstract：:This review documents important progress made in 2013 in the field of critical care respirology, in particular with regard to acute respiratory failure and acute respiratory distress syndrome. Twenty-five original articles published in the respirology and critical care sections of Critical Care are discussed in the fo...

journal_title：Critical care (London, England)

authors： Curley GF,Slutsky AS

更新日期：2014-10-15 00:00:00

abstract：INTRODUCTION:Delivery of bronchodilators with a metered-dose inhaler (MDI) and a spacer device in mechanically ventilated patients has become a widespread practice. However, except for the short-acting beta2-agonist salbutamol, the duration of action of other bronchodilators, including long-acting beta2-agonists, deliv...

journal_title：Critical care (London, England)

authors： Malliotakis P,Linardakis M,Gavriilidis G,Georgopoulos D

更新日期：2008-01-01 00:00:00

abstract：:The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivi...

journal_title：Critical care (London, England)

authors： Marshall JC

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:Severe hypoglycemia (blood glucose concentration (BG) < 40 mg/dL) is independently associated with an increased risk of mortality in critically ill patients. The association of milder hypoglycemia (BG < 70 mg/dL) with mortality is less clear. METHODS:Prospectively collected data from two observational coh...

journal_title：Critical care (London, England)

authors： Krinsley JS,Schultz MJ,Spronk PE,Harmsen RE,van Braam Houckgeest F,van der Sluijs JP,Mélot C,Preiser JC

更新日期：2011-07-25 00:00:00

abstract：INTRODUCTION:Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis. METHODS:Eleven anesthetized dogs were hemorrhaged to a mean arterial press...

journal_title：Critical care (London, England)

authors： Bruegger D,Kemming GI,Jacob M,Meisner FG,Wojtczyk CJ,Packert KB,Keipert PE,Faithfull NS,Habler OP,Becker BF,Rehm M

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Pulse-pressure variation (PPV) due to increased right ventricular afterload and dysfunction may misleadingly suggest volume responsiveness. We aimed to assess prediction of volume responsiveness with PPV in patients with increased pulmonary artery pressure. METHODS:Fifteen cardiac surgery patients with a ...

journal_title：Critical care (London, England)

authors： Wyler von Ballmoos M,Takala J,Roeck M,Porta F,Tueller D,Ganter CC,Schröder R,Bracht H,Baenziger B,Jakob SM

更新日期：2010-01-01 00:00:00

abstract：:The early recognition and management of sepsis remain the greatest challenges in the field of critical care medicine. Endothelial injury is one of the hallmarks of sepsis, leading to capillary leak, microcirculatory dysfunction, organ failure, and eventual death in many critically ill patients. The angiogenic growth f...

journal_title：Critical care (London, England)

authors： Giuliano JS Jr,Wheeler DS

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:As a result of drug sequestration and increased volume of distribution, the extracorporeal membrane oxygenation (ECMO) procedure might lead to a decrease in drug concentrations during a patient's treatment. The aim of this study was to evaluate sedative, antibiotic and immunosuppressive drug loss in ECMO c...

journal_title：Critical care (London, England)

authors： Lemaitre F,Hasni N,Leprince P,Corvol E,Belhabib G,Fillâtre P,Luyt CE,Leven C,Farinotti R,Fernandez C,Combes A

更新日期：2015-02-12 00:00:00

abstract：INTRODUCTION:Despite experimental evidence, clinical demonstration of acute state of oxidative stress and inflammation during post-cardiac arrest syndrome is lacking. Plasma level of thioredoxin (TRX), a redox-active protein induced under conditions of oxidative stress and inflammation, is increased in various critical...

journal_title：Critical care (London, England)

authors： Mongardon N,Lemiale V,Borderie D,Burke-Gaffney A,Perbet S,Marin N,Charpentier J,Pène F,Chiche JD,Mira JP,Cariou A

更新日期：2013-01-29 00:00:00

abstract：INTRODUCTION:The purpose of the present study was to critically review the existing body of evidence on ventilation modes for infants and children up to the age of 18 years. METHODS:The PubMed and EMBASE databases were searched using the search terms 'artificial respiration', 'instrumentation', 'device', 'devices', 'm...

journal_title：Critical care (London, England)

authors： Duyndam A,Ista E,Houmes RJ,van Driel B,Reiss I,Tibboel D

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Survivors of an acute critical illness with continuing organ dysfunction and uncontrolled inflammatory responses are prone to become chronically critically ill. As mental sequelae, a post-traumatic stress disorder and an associated decrease in the health-related quality of life (QoL) may occur, not only in t...

journal_title：Critical care (London, England)

authors： Wintermann GB,Petrowski K,Weidner K,Strauß B,Rosendahl J

更新日期：2019-02-08 00:00:00

abstract：: ...

journal_title：Critical care (London, England)

authors： Yamaga S,Ohshimo S,Shime N

更新日期：2019-01-17 00:00:00

abstract：INTRODUCTION:Elevated serum levels of S100beta, an astrocyte-derived protein, correlate with unfavourable neurological outcomes following cardiac surgery, neurotrauma, and resuscitation. This study evaluated whether pre-/postoperative serum S100beta levels correlate with unfavourable clinical and radiological findings ...

journal_title：Critical care (London, England)

authors： Einav S,Shoshan Y,Ovadia H,Matot I,Hersch M,Itshayek E

更新日期：2006-01-01 00:00:00

abstract：:In a group of postoperative patients, Taniguchi and coworkers compared the effect of a computerized system for weaning against 'manual care'. The computerized system involved automatic adjustments to the level of pressure support to achieve a target respiratory rate. Manual care involved adjustments to the level of pr...

journal_title：Critical care (London, England)

authors： Adigüzel N,Güngör G,Tobin MJ

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Following trauma, patients may suffer an overwhelming pro-inflammatory response and immune paralysis resulting in infection and multiple organ failure (MOF). Various potentially immunomodulative interventions have been tested. The objective of this study is to systematically review the randomized controlle...

journal_title：Critical care (London, England)

authors： Spruijt NE,Visser T,Leenen LP

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Critically ill patients and families rely upon physicians to provide estimates of prognosis and recommendations for care. Little is known about patient and clinician factors which influence these predictions. The association between these predictions and recommendations for continued aggressive care is als...

journal_title：Critical care (London, England)

authors： O'Brien JM Jr,Aberegg SK,Ali NA,Diette GB,Lemeshow S

更新日期：2009-01-01 00:00:00