Transfusion trigger: when to transfuse?

Abstract:

:The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivists' transfusion practices. Conventional transfusion triggers of 100 g/l have been challenged by reports indicating that aerobic metabolism is supported by hemoglobin levels of 50 g/l or less. Evidence from randomized trials also indicates that withholding transfusions may result in improved outcomes. Arbitrary numeric hemoglobin triggers, however, cannot supercede intervention based on individual physiologic need and clinical circumstances.

journal_name

Crit Care

authors

Marshall JC

doi

10.1186/cc2846

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

S31-3

eissn

1364-8535

issn

1466-609X

pii

cc2846

journal_volume

8 Suppl 2

pub_type

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