Pre-emptive antibiotic therapy to reduce ventilator-associated pneumonia: "thinking outside the box".

abstract：:Recent studies challenge the utility of central venous pressure monitoring as a surrogate for cardiac preload. Starting with Starling's original studies on the regulation of cardiac output, this review traces the history of the experiments that elucidated the role of central venous pressure in circulatory physiology. ...

journal_title：Critical care (London, England)

authors： Berlin DA,Bakker J

更新日期：2015-02-16 00:00:00

abstract：BACKGROUND:Hypernatraemia is common in inpatients and is associated with substantial morbidity. Its differential diagnosis is challenging, and delayed treatment may have devastating consequences. The most important hormone for the regulation of water homeostasis is arginine vasopressin, and copeptin, the C-terminal por...

journal_title：Critical care (London, England)

authors： Nigro N,Winzeler B,Suter-Widmer I,Schuetz P,Arici B,Bally M,Refardt J,Betz M,Gashi G,Urwyler SA,Burget L,Blum CA,Bock A,Huber A,Müller B,Christ-Crain M

更新日期：2018-02-09 00:00:00

abstract：INTRODUCTION:It is unknown whether the reported short-term reduction in cardiac arrests associated with the introduction of the medical emergency team (MET) system can be sustained. METHOD:We conducted a prospective, controlled before-and-after examination of the effect of a MET system on the long-term incidence of ca...

journal_title：Critical care (London, England)

authors： Jones D,Bellomo R,Bates S,Warrillow S,Goldsmith D,Hart G,Opdam H,Gutteridge G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy in acute respiratory distress syndrome (ARDS) patients but is associated with complications and costs. Here, we validate various scores supposed to predict mortality and develop an optimized categorical model. METHODS:In a derivation cohort...

journal_title：Critical care (London, England)

authors： Hilder M,Herbstreit F,Adamzik M,Beiderlinden M,Bürschen M,Peters J,Frey UH

更新日期：2017-12-12 00:00:00

abstract：:Despite continuous advances in technologic and pharmacologic management, the mortality rate from septic shock remains high. Care of patients with sepsis includes measures to support the circulatory system and treat the underlying infection. There is a substantial body of knowledge indicating that fluid resuscitation, ...

journal_title：Critical care (London, England)

authors： Waxman AB,Ward N,Thompson T,Lilly CM,Lisbon A,Hill N,Nasraway SA,Heard S,Corwin H,Levy M

更新日期：2005-08-20 00:00:00

abstract：:Ventilator-induced lung injury (VILI) consists of tissue damage and a biological response resulting from the application of inappropriate mechanical forces to the lung parenchyma. The current paradigm attributes VILI to overstretching due to very high-volume ventilation (volutrauma) and cyclic changes in aeration due ...

journal_title：Critical care (London, England)

authors： Albaiceta GM,Blanch L

更新日期：2011-04-07 00:00:00

abstract：INTRODUCTION:Procalcitonin (PCT) and C-reactive protein (CRP) are established markers of infection in the general population. In contrast, several studies reported falsely increased PCT levels in patients receiving T-cell antibodies. We evaluated the validity of these markers in patients scheduled for hemopoietic stem ...

journal_title：Critical care (London, England)

authors： Brodska H,Drabek T,Malickova K,Kazda A,Vitek A,Zima T,Markova M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Pre-hospital triage is a key element in a trauma system that aims to admit patients to the most suitable trauma center, and may decrease intra-hospital mortality. We evaluated the performance of a pre-hospital procedure in a regional trauma system through measurements of the quality of pre-hospital medical...

journal_title：Critical care (London, England)

authors： Bouzat P,Ageron FX,Brun J,Levrat A,Berthet M,Rancurel E,Thouret JM,Thony F,Arvieux C,Payen JF,TRENAU group.

更新日期：2015-03-18 00:00:00

abstract：:Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular re...

journal_title：Critical care (London, England)

authors： Tomlinson LA,Forni LG

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Recurrent delivery of tidal mechanical energy (ME) inflicts ventilator-induced lung injury (VILI) when stress and strain exceed the limits of tissue tolerance. Mechanical power (MP) is the mathematical description of the ME delivered to the respiratory system over time. It is unknown how ME relates to underl...

journal_title：Critical care (London, England)

authors： Kneyber MCJ,Ilia S,Koopman AA,van Schelven P,van Dijk J,Burgerhof JGM,Markhorst DG,Blokpoel RGT

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Esophageal pressure (Pes) can provide information to guide mechanical ventilation in acute respiratory failure. However, both relative changes and absolute values of Pes can be affected by inappropriate filling of the esophageal balloon and by the elastance of the esophagus wall. We evaluated the feasibility...

journal_title：Critical care (London, England)

authors： Mojoli F,Iotti GA,Torriglia F,Pozzi M,Volta CA,Bianzina S,Braschi A,Brochard L

更新日期：2016-04-11 00:00:00

abstract：:Organ failure in the heart or kidney can initiate various complex metabolic, cell-mediated and humoral pathways affecting distant organs, contributing to the high therapeutic costs and significantly higher morbidity and mortality. The universal outreach of cells in an injured state has myriad consequences to distant o...

journal_title：Critical care (London, England)

authors： Virzì G,Day S,de Cal M,Vescovo G,Ronco C

更新日期：2014-01-06 00:00:00

abstract：INTRODUCTION:Continuous renal replacement therapy (CRRT) has been widely used in critically ill acute kidney injury (AKI) patients. Moreover, some centers operate a specialized CRRT team (SCT) composed of physicians and nurses, but few studies have yet determined the superiority of SCT control. METHODS:A total of 334 ...

journal_title：Critical care (London, England)

authors： Oh HJ,Lee MJ,Kim CH,Kim DY,Lee HS,Park JT,Na S,Han SH,Kang SW,Koh SO,Yoo TH

更新日期：2014-08-13 00:00:00

abstract：:Lobar atelectasis is a common problem caused by a variety of mechanisms including resorption atelectasis due to airway obstruction, passive atelectasis from hypoventilation, compressive atelectsis from abdominal distension and adhesive atelectasis due to increased surface tension. However, evidence-based studies on th...

journal_title：Critical care (London, England)

authors： Schindler MB

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen concentrate, which may have advantages of more rapid administrati...

journal_title：Critical care (London, England)

authors： Curry N,Foley C,Wong H,Mora A,Curnow E,Zarankaite A,Hodge R,Hopkins V,Deary A,Ray J,Moss P,Reed MJ,Kellett S,Davenport R,Stanworth S

更新日期：2018-06-18 00:00:00

abstract：INTRODUCTION:Pulse-pressure variation (PPV) due to increased right ventricular afterload and dysfunction may misleadingly suggest volume responsiveness. We aimed to assess prediction of volume responsiveness with PPV in patients with increased pulmonary artery pressure. METHODS:Fifteen cardiac surgery patients with a ...

journal_title：Critical care (London, England)

authors： Wyler von Ballmoos M,Takala J,Roeck M,Porta F,Tueller D,Ganter CC,Schröder R,Bracht H,Baenziger B,Jakob SM

更新日期：2010-01-01 00:00:00

abstract：:The future of critical care medicine will be shaped not only by the evidence-validated foundations of science, but also by innovations based on unproven and, in many cases, untested concepts and thoughtful visions of scientists and clinicians familiar with the complex problems actually faced in clinical practice. Clin...

journal_title：Critical care (London, England)

authors： Marini JJ,Vincent JL,Wischmeyer P,Singer M,Gattinoni L,Ince C,Gan TJ

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Contrast-enhanced ultrasound (CEUS) is a new technique that might enable portable and non-invasive organ perfusion quantification at the bedside. However, it has not yet been tested in critically ill patients. We sought to establish CEUS's feasibility, safety, reproducibility and potential diagnostic value...

journal_title：Critical care (London, England)

authors： Schneider AG,Goodwin MD,Schelleman A,Bailey M,Johnson L,Bellomo R

更新日期：2013-07-12 00:00:00

abstract：:The recent bus crash in Switzerland involving many children provides several lessons for the pre-hospital care community. The use of multiple helicopters that are capable of flying at night and that carry advanced medical pre-hospital teams undoubtedly saved lives following the tragedy. We describe the medical respons...

journal_title：Critical care (London, England)

authors： Lyon RM,Sanders J

更新日期：2012-07-11 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the critically ill and is associated with adverse outcomes. Although there are plausible benefits from conversion and maintenance of sinus rhythm (the so-called 'rhythm-control' strategy), recent randomized trials have failed to demonstrate th...

journal_title：Critical care (London, England)

authors： Lim HS,Hamaad A,Lip GY

更新日期：2004-08-01 00:00:00

abstract：:Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is an increasingly adopted life-saving mechanical circulatory support for a number of potentially reversible or treatable cardiac diseases. It is also started as a bridge-to-transplantation/ventricular assist device in the case of unrecoverable cardiac or ca...

journal_title：Critical care (London, England)

authors： Bonicolini E,Martucci G,Simons J,Raffa GM,Spina C,Coco VL,Arcadipane A,Pilato M,Lorusso R

更新日期：2019-07-30 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether the degree of fluid responsiveness in critically ill septic patients is related to baseline mixed venous oxygen saturation (SvO2) levels. We also sought to define whether fluid responsiveness would be less likely in the presence of a high SvO2 (>70%). METHODS...

journal_title：Critical care (London, England)

authors： Velissaris D,Pierrakos C,Scolletta S,De Backer D,Vincent JL

更新日期：2011-07-26 00:00:00

abstract：:In the publication of this article [1], there are 4 collaborating authors missing from the 'MARS consortium'. This has now been included in this correction article. ...

journal_title：Critical care (London, England)

authors： Klein Klouwenberg PMC,Spitoni C,van der Poll T,Bonten MJ,Cremer OL,MARS consortium.

更新日期：2020-02-06 00:00:00

abstract：:The past 15 years have seen major advances in our understanding of severity assessment in community-acquired pneumonia (CAP). Prognostic tools have been promoted to guide all major management decisions in CAP, including admission to the critical care unit. Several recent studies, including the study by Renaud and coll...

journal_title：Critical care (London, England)

authors： Chalmers JD

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats. METHODS:This prospective, randomized, controlled laboratory study was conducted in...

journal_title：Critical care (London, England)

authors： Birnbaum J,Klotz E,Spies CD,Lorenz B,Stuebs P,Hein OV,Grundling M,Pavlovic D,Usichenko T,Wendt M,Kox WJ,Lehmann C

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Delayed gastric emptying occurs frequently in critically ill patients and has the potential to adversely affect both the rate, and extent, of nutrient absorption. However, there is limited information about nutrient absorption in the critically ill, and the relationship between gastric emptying (GE) and ab...

journal_title：Critical care (London, England)

authors： Chapman MJ,Fraser RJ,Matthews G,Russo A,Bellon M,Besanko LK,Jones KL,Butler R,Chatterton B,Horowitz M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Management of daily activities in ICUs is challenging. ICU shift leaders, charge nurses and intensivists have to make several immediate ad hoc decisions to enable the fluent flow of ICU activities. Even though the management of ICU activities is quite well delineated by international consensus guidelines, ...

journal_title：Critical care (London, England)

authors： Lundgrén-Laine H,Kontio E,Perttilä J,Korvenranta H,Forsström J,Salanterä S

更新日期：2011-08-08 00:00:00

abstract：INTRODUCTION:Some types of antimicrobial-coated central venous catheters (A-CVC) have been shown to be cost effective in preventing catheter-related bloodstream infection (CR-BSI). However, not all types have been evaluated, and there are concerns over the quality and usefulness of these earlier studies. There is uncer...

journal_title：Critical care (London, England)

authors： Halton KA,Cook DA,Whitby M,Paterson DL,Graves N

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Subarachnoid haemorrhage (SAH) may damage the hypothalamo-pituitary-adrenal gland (HPA) axis and disturb cortisol metabolism. There are no available data that relates to the response of the HPA axis in the acute phase of SAH. We aimed to characterise the behavior of serum adrenocorticotropic hormone (ACTH)...

journal_title：Critical care (London, England)

authors： Bendel S,Koivisto T,Ruokonen E,Rinne J,Romppanen J,Vauhkonen I,Kiviniemi V,Uusaro A

更新日期：2008-01-01 00:00:00

abstract：:Mechanical ventilation associated lung injury (VALI) negatively impacts the outcomes of critically ill patients. Research during the past two decades has led to a better understanding of key physiologic mechanisms of injury, yet uncertainty over the topographical distribution of these mechanisms continues to fuel cont...

journal_title：Critical care (London, England)

authors： Oeckler RA,Hubmayr RD

更新日期：2007-01-01 00:00:00