Clinical review: Intensive care follow-up--what has it told us?


:The majority of intensive care practitioners, until comparatively recently, was content to discharge surviving patients to the care of referring primary specialty colleagues who would undertake subsequent inpatient and outpatient care. With the exception of mortality statistics from clinical studies, the practitioners were thus denied the opportunity of understanding the full impact of critical illness on a patient and their family. The concept of the intensive care follow-up clinic has developed more recently, and is run commonly on multidisciplinary lines. These clinics serve a number of purposes, but importantly have drawn attention to broader patient-centred outcomes after intensive care. Investigators are just beginning to identify, and in some cases quantify, the postdischarge burden on patient and family; additional useful data have also come from follow-up of specific disease states. The purpose of the present review is to highlight some of the important issues that impact on recovery from critical illness towards an acceptable quality of postdischarge life. We have concentrated on the adult literature, and specifically on studies that inform us about the more general effects of critical illness. Head and spinal injury are thus largely ignored, as the effects of the primary injury overwhelm the effects of 'general' critical illness.


Crit Care


Broomhead LR,Brett SJ





Has Abstract


2002-10-01 00:00:00












  • The epidemiology of septic shock in French intensive care units: the prospective multicenter cohort EPISS study.

    abstract:INTRODUCTION:To provide up-to-date information on the prognostic factors associated with 28-day mortality in a cohort of septic shock patients in intensive care units (ICUs). METHODS:Prospective, multicenter, observational cohort study in ICUs from 14 French general (non-academic) and university teaching hospitals. Al...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Quenot JP,Binquet C,Kara F,Martinet O,Ganster F,Navellou JC,Castelain V,Barraud D,Cousson J,Louis G,Perez P,Kuteifan K,Noirot A,Badie J,Mezher C,Lessire H,Pavon A

    更新日期:2013-04-25 00:00:00

  • Potential confounders for the effect of high-flow nasal cannula oxygen therapy.

    abstract:: ...

    journal_title:Critical care (London, England)

    pub_type: 评论,信件


    authors: Yamaga S,Ohshimo S,Shime N

    更新日期:2019-01-17 00:00:00

  • Muscle regeneration after sepsis.

    abstract::Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but m...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Bouglé A,Rocheteau P,Sharshar T,Chrétien F

    更新日期:2016-05-19 00:00:00

  • Bending the cost curve in the United States: the role of comparative effectiveness research.

    abstract::Owing to an increasing focus on the rising cost of medical care in the United States, bending the cost curve has become the central tenet of healthcare reform. The exact definition of this phrase, however, remains elusive. In order to affect change in the cost and quality of healthcare, the importance of comparative e...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Ghaferi AA

    更新日期:2010-01-01 00:00:00

  • Use of machine learning to analyse routinely collected intensive care unit data: a systematic review.

    abstract:BACKGROUND:Intensive care units (ICUs) face financial, bed management, and staffing constraints. Detailed data covering all aspects of patients' journeys into and through intensive care are now collected and stored in electronic health records: machine learning has been used to analyse such data in order to provide dec...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Shillan D,Sterne JAC,Champneys A,Gibbison B

    更新日期:2019-08-22 00:00:00

  • Critical illness-induced dysglycaemia: diabetes and beyond.

    abstract::Type 2 diabetes has reached epidemic proportions in many parts of the world. The disease is projected to continue to increase and double within the foreseeable future. Dysglycaemia develops in the form of hyperglycaemia, hypoglycaemia and marked glucose variability in critically ill adults whether they are known to ha...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Smith FG,Sheehy AM,Vincent JL,Coursin DB

    更新日期:2010-01-01 00:00:00

  • Transpulmonary thermodilution for hemodynamic measurements in severely burned children.

    abstract:INTRODUCTION:Monitoring of hemodynamic and volumetric parameters after severe burns is of critical importance. Pulmonary artery catheters, however, have been associated with many risks. Our aim was to show the feasibility of continuous monitoring with minimally invasive transpulmonary thermodilution (TPTD) in severely ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Branski LK,Herndon DN,Byrd JF,Kinsky MP,Lee JO,Fagan SP,Jeschke MG

    更新日期:2011-01-01 00:00:00

  • Evaluation of pathogen detection from clinical samples by real-time polymerase chain reaction using a sepsis pathogen DNA detection kit.

    abstract:INTRODUCTION:Sepsis is a serious medical condition that requires rapidly administered, appropriate antibiotic treatment. Conventional methods take three or more days for final pathogen identification and antimicrobial susceptibility testing. We organized a prospective observational multicenter study in three study site...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Yanagihara K,Kitagawa Y,Tomonaga M,Tsukasaki K,Kohno S,Seki M,Sugimoto H,Shimazu T,Tasaki O,Matsushima A,Ikeda Y,Okamoto S,Aikawa N,Hori S,Obara H,Ishizaka A,Hasegawa N,Takeda J,Kamihira S,Sugahara K,Asari S,Mur

    更新日期:2010-01-01 00:00:00

  • Critically ill patients with Middle East respiratory syndrome coronavirus infection.

    abstract::This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at Further information about the Annual Update in Intensive Care and Emergency Medicine is available f...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Al-Dorzi HM,Alsolamy S,Arabi YM

    更新日期:2016-03-16 00:00:00

  • Value of arterial blood gas analysis in patients with acute dyspnea: an observational study.

    abstract:INTRODUCTION:The diagnostic and prognostic value of arterial blood gas analysis (ABGA) parameters in unselected patients presenting with acute dyspnea to the Emergency Department (ED) is largely unknown. METHODS:We performed a post-hoc analysis of two different prospective studies to investigate the diagnostic and pro...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Burri E,Potocki M,Drexler B,Schuetz P,Mebazaa A,Ahlfeld U,Balmelli C,Heinisch C,Noveanu M,Breidthardt T,Schaub N,Reichlin T,Mueller C

    更新日期:2011-01-01 00:00:00

  • Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity.

    abstract:BACKGROUND:In order to improve assessment and outcome prediction in patients suffering from traumatic brain injury (TBI), cerebral protein levels in serum have been suggested as biomarkers of injury. However, despite much investigation, biomarkers have yet to reach broad clinical utility in TBI. This study is a 9-year ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Thelin EP,Jeppsson E,Frostell A,Svensson M,Mondello S,Bellander BM,Nelson DW

    更新日期:2016-09-08 00:00:00

  • Partial pressure of end-tidal carbon dioxide successful predicts cardiopulmonary resuscitation in the field: a prospective observational study.

    abstract:INTRODUCTION:Prognosis in patients suffering out-of-hospital cardiac arrest is poor. Higher survival rates have been observed only in patients with ventricular fibrillation who were fortunate enough to have basic and advanced life support initiated soon after cardiac arrest. An ability to predict cardiac arrest outcome...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Kolar M,Krizmaric M,Klemen P,Grmec S

    更新日期:2008-01-01 00:00:00

  • Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus.

    abstract::COVID-19 has caused great devastation in the past year. Multi-organ point-of-care ultrasound (PoCUS) including lung ultrasound (LUS) and focused cardiac ultrasound (FoCUS) as a clinical adjunct has played a significant role in triaging, diagnosis and medical management of COVID-19 patients. The expert panel from 27 co...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Hussain A,Via G,Melniker L,Goffi A,Tavazzi G,Neri L,Villen T,Hoppmann R,Mojoli F,Noble V,Zieleskiewicz L,Blanco P,Ma IWY,Wahab MA,Alsaawi A,Al Salamah M,Balik M,Barca D,Bendjelid K,Bouhemad B,Bravo-Figueroa P,Br

    更新日期:2020-12-24 00:00:00

  • Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.

    abstract:BACKGROUND:Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARD...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Boyle AJ,Madotto F,Laffey JG,Bellani G,Pham T,Pesenti A,Thompson BT,O'Kane CM,Deane AM,McAuley DF,LUNG SAFE Investigators.,ESICM Trials Group.

    更新日期:2018-10-27 00:00:00

  • The World Trade Center attack. Lessons for all aspects of health care.

    abstract::The attack on the World Trade Center had the potential to overwhelm New York's health services. Sadly, however, the predicted thousands of treatable patients failed to materialize. Horror and sadness has now been replaced by anger, fear, and the determination to be better prepared next time. This determination not onl...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Tamber PS,Vincent JL

    更新日期:2001-12-01 00:00:00

  • Use of ultrasound guidance to improve the safety of percutaneous dilatational tracheostomy: a literature review.

    abstract::Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Alansari M,Alotair H,Al Aseri Z,Elhoseny MA

    更新日期:2015-05-18 00:00:00

  • Physiology of the Respiratory Drive in ICU Patients: Implications for Diagnosis and Treatment.

    abstract::This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at Further information about the Annual Update in Intensive Care and Emergency Medicine is available ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Jonkman AH,de Vries HJ,Heunks LMA

    更新日期:2020-03-24 00:00:00

  • Multimorbidity states associated with higher mortality rates in organ dysfunction and sepsis: a data-driven analysis in critical care.

    abstract:BACKGROUND:Sepsis remains a complex medical problem and a major challenge in healthcare. Diagnostics and outcome predictions are focused on physiological parameters with less consideration given to patients' medical background. Given the aging population, not only are diseases becoming increasingly prevalent but occur ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Zador Z,Landry A,Cusimano MD,Geifman N

    更新日期:2019-07-08 00:00:00

  • Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China.

    abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) is a newly emerging infectious disease and rapidly escalating epidemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of COVID-19 remains to be elucidated. We aimed to clarify correlation of systemic inflammation with disease s...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Zeng Z,Yu H,Chen H,Qi W,Chen L,Chen G,Yan W,Chen T,Ning Q,Han M,Wu D

    更新日期:2020-08-27 00:00:00

  • Prehospital identification of trauma patients with early acute coagulopathy and massive bleeding: results of a prospective non-interventional clinical trial evaluating the Trauma Induced Coagulopathy Clinical Score (TICCS).

    abstract:INTRODUCTION:Identifying patients who need damage control resuscitation (DCR) early after trauma is pivotal for adequate management of their critical condition. Several trauma-scoring systems have been developed to identify such patients, but most of them are not simple enough to be used in prehospital settings in the ...

    journal_title:Critical care (London, England)

    pub_type: 临床试验,杂志文章


    authors: Tonglet ML,Minon JM,Seidel L,Poplavsky JL,Vergnion M

    更新日期:2014-11-26 00:00:00

  • Pre-existing atrial fibrillation and risk of arterial thromboembolism and death in intensive care unit patients: a population-based cohort study.

    abstract:INTRODUCTION:Pre-existing atrial fibrillation (AF) may worsen prognosis in patients admitted to the intensive care unit (ICU). METHODS:In a cohort study (2005-2011) including all patients with first-time ICU admissions in Denmark (n=57,110), we compared patients with and without pre-existing AF and estimated absolute ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Gamst J,Christiansen CF,Rasmussen BS,Rasmussen LH,Thomsen RW

    更新日期:2015-08-19 00:00:00

  • Association between time of discharge from ICU and hospital mortality: a systematic review and meta-analysis.

    abstract:BACKGROUND:Epidemiological studies have provided inconsistent results on whether intensive care unit (ICU) discharge at night and on weekends is associated with an increased risk of mortality. This systematic review and meta-analysis aimed to determine whether ICU discharge time was associated with hospital mortality. ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,meta分析,评审


    authors: Yang S,Wang Z,Liu Z,Wang J,Ma L

    更新日期:2016-12-01 00:00:00

  • Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial.

    abstract:BACKGROUND:Simvastatin therapy for patients with acute respiratory distress syndrome (ARDS) has been shown to be safe and associated with minimal adverse effects, but it does not improve clinical outcomes. The aim of this research was to report on mortality and cost-effectiveness of simvastatin in patients with ARDS at...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Agus A,Hulme C,Verghis RM,McDowell C,Jackson C,O'Kane CM,Laffey JG,McAuley DF

    更新日期:2017-05-17 00:00:00

  • The effect of glutamine infusion on the inflammatory response and HSP70 during human experimental endotoxaemia.

    abstract:INTRODUCTION:Glutamine supplementation has beneficial effects on morbidity and mortality in critically ill patients, possibly in part through an attenuation of the proinflammatory cytokine response and a stimulation of heat shock protein (HSP)70. We infused either alanine-glutamine or saline during endotoxin challenge ...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,随机对照试验


    authors: Andreasen AS,Pedersen-Skovsgaard T,Mortensen OH,van Hall G,Moseley PL,Pedersen BK

    更新日期:2009-01-01 00:00:00

  • Vasopressin improves outcome in out-of-hospital cardiopulmonary resuscitation of ventricular fibrillation and pulseless ventricular tachycardia: a observational cohort study.

    abstract:INTRODUCTION:An increasing body of evidence from laboratory and clinical studies suggests that vasopressin may represent a promising alternative vasopressor for use during cardiac arrest and resuscitation. Current guidelines for cardiopulmonary resuscitation recommend the use of adrenaline (epinephrine), with vasopress...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Grmec S,Mally S

    更新日期:2006-02-01 00:00:00

  • Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha.

    abstract::A progressive rise of oxidative stress due to altered reduction-oxidation (redox) homeostasis appears to be one of the hallmarks of the processes that regulate gene transcription in physiology and pathophysiology. Reactive oxygen species and reactive nitrogen species serve as signaling messengers for the evolution and...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Haddad JJ

    更新日期:2003-02-01 00:00:00

  • In vivo validation of the adequacy calculator for continuous renal replacement therapies.

    abstract:INTRODUCTION:The study was conducted to validate in vivo the Adequacy Calculator, a Microsoft Excel-based program, designed to assess the prescription and delivery of renal replacement therapy in the critical care setting. METHODS:The design was a prospective cohort study, set in two intensive care units of teaching h...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,多中心研究


    authors: Ricci Z,Salvatori G,Bonello M,Pisitkun T,Bolgan I,D'Amico G,Dan M,Piccinni P,Ronco C

    更新日期:2005-06-01 00:00:00

  • Effect of glomerular filtration rate impairment on diagnostic performance of neutrophil gelatinase-associated lipocalin and B-type natriuretic peptide as markers of acute cardiac and renal failure in chronic kidney disease patients.

    abstract:INTRODUCTION:Cardio-renal syndromes are characterized by the impairment of cardiac and renal functions. Plasma and urinary neutrophil gelatinase-associated lipocalin (NGAL), and plasma B-type natriuretic peptide (BNP) are markers of acute kidney injury (AKI) and heart failure (HF), respectively. METHODS:GFR (99mTc-DTP...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章


    authors: Donadio C

    更新日期:2014-02-28 00:00:00

  • Clinical review: Drug metabolism and nonrenal clearance in acute kidney injury.

    abstract::Decreased renal drug clearance is an obvious consequence of acute kidney injury (AKI). However, there is growing evidence to suggest that nonrenal drug clearance is also affected. Data derived from human and animal studies suggest that hepatic drug metabolism and transporter function are components of nonrenal clearan...

    journal_title:Critical care (London, England)

    pub_type: 杂志文章,评审


    authors: Vilay AM,Churchwell MD,Mueller BA

    更新日期:2008-01-01 00:00:00

  • The diagnosis of adrenal insufficiency in the critically ill patient: does it really matter?

    abstract::The definition of what constitutes a 'normal' adrenal response to critical illness is unclear. Consequently, published studies have used a variety of biochemical criteria to define 'adrenal insufficiency'. These criteria have been based on the baseline cortisol level or the increment in cortisol following corticotropi...

    journal_title:Critical care (London, England)

    pub_type: 评论,杂志文章


    authors: Marik PE

    更新日期:2006-01-01 00:00:00