Abstract:
:The majority of intensive care practitioners, until comparatively recently, was content to discharge surviving patients to the care of referring primary specialty colleagues who would undertake subsequent inpatient and outpatient care. With the exception of mortality statistics from clinical studies, the practitioners were thus denied the opportunity of understanding the full impact of critical illness on a patient and their family. The concept of the intensive care follow-up clinic has developed more recently, and is run commonly on multidisciplinary lines. These clinics serve a number of purposes, but importantly have drawn attention to broader patient-centred outcomes after intensive care. Investigators are just beginning to identify, and in some cases quantify, the postdischarge burden on patient and family; additional useful data have also come from follow-up of specific disease states. The purpose of the present review is to highlight some of the important issues that impact on recovery from critical illness towards an acceptable quality of postdischarge life. We have concentrated on the adult literature, and specifically on studies that inform us about the more general effects of critical illness. Head and spinal injury are thus largely ignored, as the effects of the primary injury overwhelm the effects of 'general' critical illness.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Broomhead LR,Brett SJdoi
10.1186/cc1532keywords:
subject
Has Abstractpub_date
2002-10-01 00:00:00pages
411-7issue
5eissn
1364-8535issn
1466-609Xjournal_volume
6pub_type
杂志文章,评审相关文献
CRITICAL CARE文献大全abstract::Certain noble gases, though inert, exhibit remarkable biological properties. Notably, xenon and argon provide neuroprotection in animal models of central nervous system injury. In the previous issue of Critical Care, Loetscher and colleagues provided further evidence that argon may have therapeutic properties for neur...
journal_title:Critical care (London, England)
pub_type: 评论,信件
doi:10.1186/cc8847
更新日期:2010-01-01 00:00:00
abstract::Several prognostic markers have been identified for patients admitted with acute cardiogenic pulmonary edema. Most of the markers are based on clinical risk scores. Unlike hypercapnic respiratory failure, acidosis is not an adverse predictor in these patients. Hemodynamic variables that assess pathophysiological mecha...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章,评审
doi:10.1186/cc9325
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Intensive care medicine is a relatively young discipline that has rapidly grown into a full-fledged medical subspecialty. Intensivists are responsible for managing an ever-increasing number of patients with complex, life-threatening diseases. Several factors may influence their performance, including age, tr...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-018-1956-6
更新日期:2018-02-21 00:00:00
abstract:INTRODUCTION:Impaired skeletal muscle function has important clinical outcome implications for survivors of critical illness. Previous studies employing volitional manual muscle testing for diagnosing intensive care unit-acquired weakness (ICU-AW) during the early stages of critical illness have only provided limited d...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13052
更新日期:2013-10-10 00:00:00
abstract::Patients in ICUs frequently require tracheostomy for long-term ventilator support, and the percutaneous dilatational tracheostomy (PDT) method is preferred over surgical tracheostomy. The use of ultrasound (US) imaging to guide ICU procedures and interventions has recently emerged as a simple and noninvasive tool. The...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-015-0942-5
更新日期:2015-05-18 00:00:00
abstract:INTRODUCTION:The aim of this study was to determine whether using pharmacodynamic-based dosing of antimicrobials, such as extended/continuous infusions, in critically ill patients is associated with improved outcomes as compared with traditional dosing methods. METHODS:We searched Medline, HealthStar, EMBASE, Cochrane...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析,评审
doi:10.1186/cc13134
更新日期:2013-11-29 00:00:00
abstract:BACKGROUND:Atrial fibrillation occurs frequently in patients following cardiac surgery and can be a cause of increased morbidity and mortality. The use of dexmedetomidine to prevent atrial fibrillation is unclear. The present study was designed to evaluate the effect of dexmedetomidine sedation on the incidence of atri...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-016-1480-5
更新日期:2016-09-21 00:00:00
abstract::Considerable progress has been made recently in the understanding of how best to accomplish safe and effective ventilation of patients with acute lung injury. Mechanical and nonmechanical factors contribute to causation of ventilator-associated lung injury. Intervention timing helps determine the therapeutic efficacy ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc14722
更新日期:2015-01-01 00:00:00
abstract::Institutionally based research ethics review is a form of peer review that has - for better or worse - become the norm throughout the world. The vast majority of research ethics review takes the form of protocol review alone, conducted in advance of the research. Although oversight and monitoring in clinical research ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc2964
更新日期:2004-12-01 00:00:00
abstract:INTRODUCTION:The main objective was to determine risk factors for presence of multidrug resistant bacteria (MDR) in postoperative peritonitis (PP) and optimal empirical antibiotic therapy (EA) among options proposed by Infectious Disease Society of America and the Surgical Infection Society guidelines. METHODS:One hun...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc8877
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:The endothelial specific angiopoietin (Ang)-Tie2 ligand-receptor system has been identified as a non-redundant mediator of endothelial activation in experimental sepsis. Binding of circulating Ang-1 to the Tie2 receptor protects the vasculature from inflammation and leakage, whereas binding of Ang-2 antago...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc7130
更新日期:2008-01-01 00:00:00
abstract::In the publication of this article [1], there are 4 collaborating authors missing from the 'MARS consortium'. This has now been included in this correction article. ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,已发布勘误
doi:10.1186/s13054-020-2758-1
更新日期:2020-02-06 00:00:00
abstract:INTRODUCTION:Data on the epidemiology and management of anorexia nervosa (AN) in the intensive care unit (ICU) are scarce. The aim of this study was to evaluate the prevalence and associated morbidity and mortality of AN in French ICUs. METHODS:We randomly selected 30 ICUs throughout France. Thereafter, we retrospecti...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/cc9274
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Microcirculatory dysfunction develops in both septic and cardiogenic shock patients, and it is associated with poor prognosis in patients with septic shock. Information on the association between microcirculatory dysfunction and prognosis in cardiogenic shock patients with venoarterial extracorporeal membran...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-018-2081-2
更新日期:2018-08-19 00:00:00
abstract:BACKGROUND:Functional status (FS) before intensive care unit (ICU) admission is associated with short-term and long-term outcomes among critically ill patients. However, measures of FS are generally not integrated into ICU-specific mortality prediction models. METHODS:This retrospective cohort study used prospectively...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1688-z
更新日期:2017-05-15 00:00:00
abstract:INTRODUCTION:Following trauma, patients may suffer an overwhelming pro-inflammatory response and immune paralysis resulting in infection and multiple organ failure (MOF). Various potentially immunomodulative interventions have been tested. The objective of this study is to systematically review the randomized controlle...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc9218
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Data on prehospital and trauma-room fluid management of multiple trauma patients with pelvic disruptions are rarely reported. Present trauma algorithms recommend early hemorrhage control and massive fluid resuscitation. By matching the German Pelvic Injury Register (PIR) with the TraumaRegister DGU (TR) fo...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc11487
更新日期:2012-08-22 00:00:00
abstract::Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of h...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc4957
更新日期:2006-01-01 00:00:00
abstract::Owing to an increasing focus on the rising cost of medical care in the United States, bending the cost curve has become the central tenet of healthcare reform. The exact definition of this phrase, however, remains elusive. In order to affect change in the cost and quality of healthcare, the importance of comparative e...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc9045
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to determine whether the degree of fluid responsiveness in critically ill septic patients is related to baseline mixed venous oxygen saturation (SvO2) levels. We also sought to define whether fluid responsiveness would be less likely in the presence of a high SvO2 (>70%). METHODS...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10326
更新日期:2011-07-26 00:00:00
abstract:BACKGROUND:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1855-2
更新日期:2017-10-26 00:00:00
abstract:BACKGROUND:Diaphragm dysfunction develops frequently in ventilated intensive care unit (ICU) patients. Both disuse atrophy (ventilator over-assist) and high respiratory muscle effort (ventilator under-assist) seem to be involved. A strong rationale exists to monitor diaphragm effort and titrate support to maintain resp...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-018-2172-0
更新日期:2018-09-27 00:00:00
abstract:INTRODUCTION:Currently, little is known about the immunological characteristics of patients with avian influenza A (H7N9) virus infection. METHODS:The numbers and percentages of peripheral blood immune cells were measured in 27 patients with laboratory-confirmed H7N9 virus infection and 30 healthy controls (HCs). The ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13788
更新日期:2014-03-24 00:00:00
abstract:BACKGROUND:The incidence of seizures in intensive care units ranges from 3.3% to 34%. It is therefore often necessary to initiate or continue anticonvulsant drugs in this setting. When a new anticonvulsant is initiated, drug factors, such as onset of action and side effects, and patient factors, such as age, renal, and...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-018-2066-1
更新日期:2018-06-07 00:00:00
abstract:BACKGROUND:Our objective was to evaluate the impact of gastric versus post-pyloric feeding on the incidence of pneumonia, caloric intake, intensive care unit (ICU) length of stay (LOS), and mortality in critically ill and injured ICU patients. METHOD:Data sources were Medline, Embase, Healthstar, citation review of re...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析,评审
doi:10.1186/cc2190
更新日期:2003-06-01 00:00:00
abstract:INTRODUCTION:Takotsubo cardiomyopathy (TCM) is a life-threatening systemic consequence early after subarachnoid hemorrhage (SAH), but precise hemodynamics and related outcome have not been studied. The purpose of this study was to investigate the TCM-induced cardiac function by transpulmonary thermodilution and its imp...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-014-0482-4
更新日期:2014-08-12 00:00:00
abstract::Over the last years, there was an increase in the number and severity of Clostridium difficile infections (CDI) in all medical settings, including the intensive care unit (ICU). The current prevalence of CDI among ICU patients is estimated at 0.4-4% and has severe impact on morbidity and mortality. An estimated 10-20%...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-017-1819-6
更新日期:2017-10-22 00:00:00
abstract:BACKGROUND:Middle East respiratory syndrome coronavirus infection is associated with high mortality rates but limited clinical data have been reported. We describe the clinical features and outcomes of patients admitted to an intensive care unit (ICU) with Middle East respiratory syndrome coronavirus (MERS-CoV) infecti...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-016-1303-8
更新日期:2016-05-07 00:00:00
abstract::Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but m...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-016-1308-3
更新日期:2016-05-19 00:00:00
abstract::Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1880-1
更新日期:2017-11-19 00:00:00