Abstract:
INTRODUCTION:Data on the epidemiology and management of anorexia nervosa (AN) in the intensive care unit (ICU) are scarce. The aim of this study was to evaluate the prevalence and associated morbidity and mortality of AN in French ICUs. METHODS:We randomly selected 30 ICUs throughout France. Thereafter, we retrospectively analyzed all patients with AN admitted to any of these 30 ICUs between May 2006 and May 2008. We considered demographic data, diagnosis at admission and complications occurring during the stay, focusing on refeeding syndrome and management of refeeding. RESULTS:Eleven of the 30 ICUs participated in the retrospective study, featuring 68 patients, including 62 women. Average body mass index at the admission was 12 ± 3 kg/m2. Twenty one were mechanically ventilated, mainly for neurological reasons. The reported average calorie intake was 22.3 ± 13 kcal/kg/24 h. Major diagnoses at admission were metabolic problems, refeeding survey and voluntary drug intoxication and infection. The most common complications were metabolic, hematological, hepatic, and infectious events, of which 10% occurred during refeeding. Seven patients developed refeeding syndrome. At day one, the average calorie intake was higher for patients who developed refeeding syndrome (23.2 ± 5 Kcal/kg/j; n = 7) versus patients without refeeding syndrome (14.1 ± 3 Kcal/kg/j; n = 61) P = 0.02. Seven patients died, two from acute respiratory distress syndrome and five from multiorgan-failure associated with major hydroelectrolytic problems. CONCLUSIONS:The frequency of AN in ICU patients is very low and the crude mortality in this group is about 10%. Prevention and early-detection of refeeding syndrome is the key point.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Vignaud M,Constantin JM,Ruivard M,Villemeyre-Plane M,Futier E,Bazin JE,Annane D,AZUREA group (AnorexieRea Study Group).doi
10.1186/cc9274subject
Has Abstractpub_date
2010-01-01 00:00:00pages
R172issue
5eissn
1364-8535issn
1466-609Xpii
cc9274journal_volume
14pub_type
杂志文章,多中心研究,随机对照试验相关文献
CRITICAL CARE文献大全abstract::Platelet transfusions carry greater risks of infection, sepsis, and death than any other blood product, owing primarily to bacterial contamination. Many patients may be at particular risk, including critically ill patients in the intensive care unit. This narrative review provides an overview of the problem and an upd...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-018-2212-9
更新日期:2018-10-27 00:00:00
abstract:INTRODUCTION:Improved methods to optimize drug dosing in the critically ill are urgently needed. Traditional prescribing culture involves recognition of factors that mandate dose reduction (such as renal impairment), although optimizing drug exposure, through more frequent or augmented dosing, represents an evolving st...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc12544
更新日期:2013-02-28 00:00:00
abstract::Mechanical ventilation associated lung injury (VALI) negatively impacts the outcomes of critically ill patients. Research during the past two decades has led to a better understanding of key physiologic mechanisms of injury, yet uncertainty over the topographical distribution of these mechanisms continues to fuel cont...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章,评审
doi:10.1186/cc6160
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Impaired skeletal muscle function has important clinical outcome implications for survivors of critical illness. Previous studies employing volitional manual muscle testing for diagnosing intensive care unit-acquired weakness (ICU-AW) during the early stages of critical illness have only provided limited d...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13052
更新日期:2013-10-10 00:00:00
abstract:: ...
journal_title:Critical care (London, England)
pub_type: 社论
doi:10.1186/s13054-018-2203-x
更新日期:2018-11-03 00:00:00
abstract:INTRODUCTION:Uncalibrated arterial pulse power analysis has been recently introduced for continuous monitoring of cardiac index (CI). The aim of the present study was to compare the accuracy of arterial pulse power analysis with intermittent transpulmonary thermodilution (TPTD) before and after cardiopulmonary bypass (...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10065
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The timing of initiation of renal replacement therapy (RRT) in severe acute kidney injury (AKI) remains controversial, with early initiation resulting in unnecessary therapy for some patients while expectant therapy may delay RRT for other patients. The furosemide stress test (FST) has been shown to predict ...
journal_title:Critical care (London, England)
pub_type: 临床试验,杂志文章
doi:10.1186/s13054-018-2021-1
更新日期:2018-04-19 00:00:00
abstract::Fluid resuscitation is a cornerstone of intensive care unit patient care, but prediction of the cardiovascular response remains difficult, despite many efforts in clinical research. The concept of responders and nonresponders illustrates such a difficulty. Many techniques have been tested, from strictly non-invasive t...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc10067
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The goal of the current study was to investigate the effect of aging on the development of endothelial dysfunction in a murine model of sepsis, and to compare it with the effect of genetic deficiency of the endothelial isoform of nitric oxide synthase (eNOS). METHODS:Cecal ligation and puncture (CLP) was ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-014-0511-3
更新日期:2014-09-16 00:00:00
abstract:: ...
journal_title:Critical care (London, England)
pub_type: 评论,信件
doi:10.1186/s13054-018-2297-1
更新日期:2019-01-09 00:00:00
abstract::This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2019. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2019 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-019-2369-x
更新日期:2019-03-09 00:00:00
abstract::Circulating cell-free DNA (cf-DNA) mainly comes from apoptotic cells and can reflect the extent of cellular damage. Increased plasma levels of cf-DNA have been found in many acute disorders, including septic and clinically ill patients, and usually correlate well with clinical outcome. Acute respiratory failure, the m...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc10365
更新日期:2011-01-01 00:00:00
abstract::Severe burn injury remains a major burden on patients and healthcare systems. Following severe burns, the injured tissues mount a local inflammatory response aiming to restore homeostasis. With excessive burn load, the immune response becomes disproportionate and patients may develop an overshooting systemic inflammat...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc7794
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Critically ill patients and families rely upon physicians to provide estimates of prognosis and recommendations for care. Little is known about patient and clinician factors which influence these predictions. The association between these predictions and recommendations for continued aggressive care is als...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc7926
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Serum concentrations of adhesion molecules may be connected to the pathogenesis of secondary brain injury after spontaneous intracerebral hemorrhage (ICH). This study posits the hypothesis that levels of adhesion molecules substantially increase after ICH and are decreased thereafter, and that they can pre...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10568
更新日期:2011-01-01 00:00:00
abstract::Sepsis and septic shock are the leading causes of acute renal failure, multiple organ system dysfunction, and death in the intensive care unit. The pathogenesis of sepsis is complex and comprises a mosaic of interconnected pathways. Several attempts to improve patient outcomes by targeting specific components of this ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1889
更新日期:2003-04-01 00:00:00
abstract:INTRODUCTION:The present study was conducted to assess the value of serum concentration of lipopolysaccharide-binding protein (LBP) in patients with systemic inflammatory response syndrome (SIRS), sepsis and septic shock with respect to its ability to differentiate between infectious and noninfectious etiologies in SIR...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc2386
更新日期:2003-12-01 00:00:00
abstract::The burden of chronic obstructive pulmonary disease on intensive care is heavy, but newer modalities of treatment are now available to improve outcomes. Cardiac-based research continues to generate new drugs and tests to better outcome and aid in early diagnosis. And how do various intensive care interventions compare...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc8130
更新日期:2009-01-01 00:00:00
abstract::Severe sepsis is more and more frequent, especially because of an increased rate of immunocompromised patients. Despite the improvement in the overall prognosis of HIV/AIDS patients and the improvement of global ICU care, the prognosis of HIV/ADS patients hospitalized in ICU with severe sepsis remained poor. This situ...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc3923
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:The pathophysiology of acute kidney injury (AKI) in sepsis is ill defined. We investigated parameters associated with low glomerular filtration, and their predictive value to discriminate transient from intrinsic septic AKI. METHODS:In 107 sepsis patients, AKI was defined by the Risk, Injury, Failure, Los...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13057
更新日期:2013-10-13 00:00:00
abstract::Despite progress in the diagnosis, prevention and therapy for hospital-acquired infections, ventilator-associated pneumonia (VAP) continues to complicate the course of a significant proportion of patients receiving mechanical ventilation. Mortality rates among patients with VAP have been reported to be as high as 72%,...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc3014
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Acute respiratory failure (ARF) remains a common hazardous complication in immunocompromised patients and is associated with increased mortality rates when endotracheal intubation is needed. We aimed to evaluate the effect of early noninvasive ventilation (NIV) compared with oxygen therapy alone in this pati...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s13054-016-1586-9
更新日期:2017-01-07 00:00:00
abstract:IMPORTANCE:The optimal approach to airway management during in-hospital cardiac arrest is unknown. OBJECTIVE:To describe hospital-level variation in endotracheal intubation during cardiopulmonary resuscitation (CPR) for in-hospital cardiac arrest and the association between hospital use of endotracheal intubation and ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-019-2426-5
更新日期:2019-05-06 00:00:00
abstract:BACKGROUND:(1,3)-β-D-Glucan has been widely used in clinical practice for the diagnosis of invasive Candida infections. However, such serum biomarker showed potential to guide antimicrobial therapy in order to reduce the duration of empirical antifungal treatment in critically ill septic patients with suspected invasiv...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-020-03265-y
更新日期:2020-09-05 00:00:00
abstract::COVID-19 has caused great devastation in the past year. Multi-organ point-of-care ultrasound (PoCUS) including lung ultrasound (LUS) and focused cardiac ultrasound (FoCUS) as a clinical adjunct has played a significant role in triaging, diagnosis and medical management of COVID-19 patients. The expert panel from 27 co...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/s13054-020-03369-5
更新日期:2020-12-24 00:00:00
abstract::The early recognition and management of sepsis remain the greatest challenges in the field of critical care medicine. Endothelial injury is one of the hallmarks of sepsis, leading to capillary leak, microcirculatory dysfunction, organ failure, and eventual death in many critically ill patients. The angiogenic growth f...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章,评审
doi:10.1186/cc7685
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Despite quick implementation of reperfusion therapies, a few patients with high-risk, acute, massive, pulmonary embolism (PE) remain highly hemodynamically unstable. Others have absolute contraindication to receive reperfusion therapies. Venoarterial-extracorporeal membrane oxygenation (VA-ECMO) might lower ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1655-8
更新日期:2017-03-28 00:00:00
abstract:INTRODUCTION:Data on the incidence of a hypercoagulable state in trauma, as measured by thromboelastometry (ROTEM), is limited and the prognostic value of hypercoagulability after trauma on outcome is unclear. We aimed to determine the incidence of hypercoagulability after trauma, and to assess whether early hypercoagu...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/s13054-014-0687-6
更新日期:2014-12-25 00:00:00
abstract:BACKGROUND:Critically ill patients in the intensive care unit (ICU) are at high risk for developing Clostridioides difficile infections (CDI). Risk factors predicting their mortality or standardized treatment recommendations have not been defined for this cohort. Our goal is to determine outcome and mortality associate...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-019-2648-6
更新日期:2019-12-09 00:00:00
abstract::Despite continuous advances in technologic and pharmacologic management, the mortality rate from septic shock remains high. Care of patients with sepsis includes measures to support the circulatory system and treat the underlying infection. There is a substantial body of knowledge indicating that fluid resuscitation, ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc2940
更新日期:2005-08-20 00:00:00